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Laboratory capture, isolation and analysis of microparticles in aerogel: Preparation for the return of Stardust
We present observations from the laboratory capture of particles in aerogel. The paper focuses on a possible extraction technique and the bulk mineral characterization of the captured material using non-destructive analytical techniques
Constraints on Jupiters from Observations of Galactic bulge microlensing events during 2000
Peer reviewe
Dielectronic Recombination in Li+ Ions
This research was sponsored by the National Science Foundation Grant NSF PHY-931478
Geochemical analysis of bulk marine sediment by Inductively Coupled Plasma–Atomic Emission Spectroscopy on board the JOIDES Resolution
Geochemical analyses on board the JOIDES Resolution have been enhanced with the addition of a Jobin-Yvon Ultrace inductively coupled plasma-atomic emission spectrometer (ICP-AES) as an upgrade from the previous X-ray fluorescence facility. During Leg 199, we sought to both challenge and utilize the capabilities of the ICP-AES in order to provide an extensive bulk-sediment geochemical database during the cruise. These near real-time analyses were then used to help characterize the recovered sedimentary sequences, calculate mass accumulation rates of the different sedimentary components, and assist with cruise and postcruise sampling requests. The general procedures, sample preparation techniques, and basic protocol for ICP-AES analyses on board ship are outlined by Murray et al. (2000) in Ocean Drilling Program Tech Note, 29. We expand on those concepts and offer suggestions for ICP-AES methodology, calibration by standard reference materials, data reduction procedures, and challenges that are specific to the analysis of bulk-sediment samples. During Leg 199, we employed an extensive bulk-sediment analytical program of ~600 samples of varying lithologies, thereby providing several opportunities for refinement of techniques. We also discuss some difficulties and challenges that were faced and suggest how to alleviate such occurrences for sedimentary chemical analyses during future legs
Exploring the Quality of Life of People in North Eastern and Southern Thailand.
The assumption that development brings not only material prosperity but also a better overall quality of life lies at the heart of the development project. Against this, critics assert that development can undermine social cohesion and threaten cultural integrity. Rarely, however, is the impact of development on wellbeing rigourously analysed using empirical data. This is what the Wellbeing in Developing Countries Group at the University of Bath aims to do drawing on fieldwork carried out in four developing countries, which addresses the themes of resources, needs, agency and structure, and subjective Quality of life (QoL). The first phase of the QoL research in Thailand aimed to explore the categories and components of quality of life for people from different backgrounds and locations with the aim of developing methods for QoL assessment in the third phase of the WeD QoL research. The study presents data obtained from rural and peri-urban sites in Southern and Northeastern Thailand (two villages in Songkhla and three in Khon Kaen, Mukdaharn, and Roi-et). Participants were divided into six groups by gender and age, and were divided again by religion (Buddhist and Muslim) and wealth status in the South. Data collection was conducted between October and December 2004 using focus group discussions, semi-structured interviews, and the Person Generated Index. Content analysis was used for data analysis. The use of a qualitative approach enabled the gathering of empirical data that reflects the sources of difficulty and happiness in the lives of participants. Respondents identified 26 aspects to their quality of life, including family relations, health and longevity, income and having money, jobs, housing, education, debt, and so on. The results reveal clear similarities and differences in the role of traditions, religious beliefs, and values in the lives of people living in remote rural or peri-urban areas in Northeastern and Southern Thailand. These results, together with the findings from Peru, Ethiopia, and Bangladesh, will inform the rest of the WeD research and be used to develop measures to assess the quality of life of people living in developing countries
Barrier effects on the collective excitations of split Bose-Einstein condensates
We investigate the collective excitations of a single-species Bose gas at T=0
in a harmonic trap where the confinement undergoes some splitting along one
spatial direction. We mostly consider onedimensional potentials consisting of
two harmonic wells separated a distance 2 z_0, since they essentially contain
all the barrier effects that one may visualize in the 3D situation. We find,
within a hydrodynamic approximation, that regardless the dimensionality of the
system, pairs of levels in the excitation spectrum, corresponding to
neighbouring even and odd excitations, merge together as one increases the
barrier height up to the current value of the chemical potential. The
excitation spectra computed in the hydrodynamical or Thomas-Fermi limit are
compared with the results of exactly solving the time-dependent
Gross-Pitaevskii equation. We analyze as well the characteristics of the
spatial pattern of excitations of threedimensional boson systems according to
the amount of splitting of the condensate.Comment: RevTeX, 12 pages, 13 ps figure
Breakdown of correspondence in chaotic systems: Ehrenfest versus localization times
Breakdown of quantum-classical correspondence is studied on an experimentally
realizable example of one-dimensional periodically driven system. Two relevant
time scales are identified in this system: the short Ehrenfest time t_h and the
typically much longer localization time scale T_L. It is shown that
surprisingly weak modification of the Hamiltonian may eliminate the more
dramatic symptoms of localization without effecting the more subtle but
ubiquitous and rapid loss of correspondence at t_h.Comment: 4 pages, 5 figures, replaced with a version submitted to PR
Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals.
BACKGROUND: Recombinant adenovirus serotype 5 (rAd5)-vectored HIV-1 vaccines have not prevented HIV-1 infection or disease and pre-existing Ad5 neutralizing antibodies may limit the clinical utility of Ad5 vectors globally. Using a rare Ad serotype vector, such as Ad35, may circumvent these issues, but there are few data on the safety and immunogenicity of rAd35 directly compared to rAd5 following human vaccination.
METHODS: HVTN 077 randomized 192 healthy, HIV-uninfected participants into one of four HIV-1 vaccine/placebo groups: rAd35/rAd5, DNA/rAd5, and DNA/rAd35 in Ad5-seronegative persons; and DNA/rAd35 in Ad5-seropositive persons. All vaccines encoded the HIV-1 EnvA antigen. Antibody and T-cell responses were measured 4 weeks post boost immunization.
RESULTS: All vaccines were generally well tolerated and similarly immunogenic. As compared to rAd5, rAd35 was equally potent in boosting HIV-1-specific humoral and cellular immunity and responses were not significantly attenuated in those with baseline Ad5 seropositivity. Like DNA, rAd35 efficiently primed rAd5 boosting. All vaccine regimens tested elicited cross-clade antibody responses, including Env V1/V2-specific IgG responses.
CONCLUSIONS: Vaccine antigen delivery by rAd35 is well-tolerated and immunogenic as a prime to rAd5 immunization and as a boost to prior DNA immunization with the homologous insert. Further development of rAd35-vectored prime-boost vaccine regimens is warranted
Vacuum local and global electromagnetic self-energies for a point-like and an extended field source
We consider the electric and magnetic energy densities (or equivalently field
fluctuations) in the space around a point-like field source in its ground
state, after having subtracted the spatially uniform zero-point energy terms,
and discuss the problem of their singular behavior at the source's position. We
show that the assumption of a point-like source leads, for a simple Hamiltonian
model of the interaction of the source with the electromagnetic radiation
field, to a divergence of the renormalized electric and magnetic energy density
at the position of the source. We analyze in detail the mathematical structure
of such singularity in terms of a delta function and its derivatives. We also
show that an appropriate consideration of these singular terms solves an
apparent inconsistency between the total field energy and the space integral of
its density. Thus the finite field energy stored in these singular terms gives
an important contribution to the self-energy of the source. We then consider
the case of an extended source, smeared out over a finite volume and described
by an appropriate form factor. We show that in this case all divergences in
local quantities such as the electric and the magnetic energy density, as well
as any inconsistency between global and space-integrated local self-energies,
disappear.Comment: 8 pages. The final publication is available at link.springer.co
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