Search for charginos, neutralinos, and gravitinos at LEP

The hep-ex data base was decided not to be an appropriate place to make DELPHI notes public. Sorry for the inconvenience.Comment: the paper should not have been made publi

A machine learning approach to evaluate the influence of higher-order generalized variables on shell free vibrations

This work focuses on deriving guidelines for choosing structural theories for composite shells using Convolutional Neural Networks (CNN). The Axiomatic/Asymptotic Method (AAM) is used to evaluate higher-order structural theories’ accuracy and computational efficiency based on polynomial expansions. AAM exploits the Carrera Unified Formulation to derive the finite element matrices and obtain natural frequencies. The outcomes of AAM concerning the accuracy and computational cost are used to train CNN for various composite shell configurations. The trained network can then be used as a substitute for finite element models to estimate the accuracy of a given structural theory. The results are provided via Best Theory Diagrams (BTD), in which the set of generalized displacement variables to retain the best accuracy can be read for a given amount of nodal degrees of freedom. Verification is carried out using results from FEM. The results proved the computational efficiency of CNN and highlighted the influence of the shell thickness for the proper choice of the structural theory. Third-order terms and transverse stretching are often necessary to obtain acceptable accuracy

The high-intensity hyperon beam at CERN

A high-intensity hyperon beam was constructed at CERN to deliver Sigma- to experiment WA89 at the Omega facility and operated from 1989 to 1994. The setup allowed rapid changeover between hyperon and conventional hadron beam configurations. The beam provided a Sigma-flux of 1.4 x 10^5 per burst at mean momenta between 330 and 345 Gev/c, produced by about 3 x 10^10 protons of 450 GeV/c . At the experiment target the beam had a Sigma-/pi- ratio close to 0.4 and a size of 1.6 x 3.7 cm^2. The beam particle trajectories and their momenta were measured with a scintillating fibre hodoscope in the beam channel and a silicon microstrip detector at the exit of the channel. A fast transition radiation detector was used to identify the pion component of the beam.Comment: 20 pages, 13 figures. Submitted to Nucl. Instr. Meth.

Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia

Hepcidin is the key regulator of systemic iron homeostasis. We describe the modulation of hepcidin production induced by plasma transfusions in a patient with congenital hypotransferrinemia that offers a unique model in which to study the mechanism of hepcidin regulation by iron and erythropoiesis. Urinary hepcidin increased from zero at baseline, when hemoglobin and serum transferrin was low, to a maximum of 98 ng/mg creatinine on day 60, and subsequently decreased. Time-course of urinary hepcidin and serum transferrin concentration suggests that hepcidin production is regulated by the combination of marrow iron requirements and iron supply by transferrin

Stopping and straggling of 60-250-keV backscattered protons on nanometric Pt films

The stopping power and straggling of backscattered protons on nanometric Pt films were measured at low to medium energies (60-250 keV) by using the medium-energy ion scattering technique. The stopping power results are in good agreement with the most recent measurements by Primetzhofer Phy s. Rev. B 86, 094102 (2012) and are well described by the free electron gas model at low projectile energies. Nevertheless, the straggling results are strongly underestimated by well-established formulas up to a factor of two. Alternatively, we propose a model for the energy-loss straggling that takes into account the inhomogeneous electron-gas response, based on the electron-loss function of the material, along with bunching effects. This approach yields remarkable agreement with the experimental data, indicating that the observed enhancement in energy-loss straggling is due to bunching effects in an inhomogeneous electron system. Nonlinear effects are of minor importance for the energy-loss straggling

Hepcidin Expression in Iron Overload Diseases Is Variably Modulated by Circulating Factors

Hepcidin is a regulatory hormone that plays a major role in controlling body iron homeostasis. Circulating factors (holotransferrin, cytokines, erythroid regulators) might variably contribute to hepcidin modulation in different pathological conditions. There are few studies analysing the relationship between hepcidin transcript and related protein expression profiles in humans. Our aims were: a. to measure hepcidin expression at either hepatic, serum and urinary level in three paradigmatic iron overload conditions (hemochromatosis, thalassemia and dysmetabolic iron overload syndrome) and in controls; b. to measure mRNA hepcidin expression in two different hepatic cell lines (HepG2 and Huh-7) exposed to patients and controls sera to assess whether circulating factors could influence hepcidin transcription in different pathological conditions. Our findings suggest that hepcidin assays reflect hepatic hepcidin production, but also indicate that correlation is not ideal, likely due to methodological limits and to several post-trascriptional events. In vitro study showed that THAL sera down-regulated, HFE-HH and C-NAFLD sera up-regulated hepcidin synthesis. HAMP mRNA expression in Huh-7 cells exposed to sera form C-Donors, HFE-HH and THAL reproduced, at lower level, the results observed in HepG2, suggesting the important but not critical role of HFE in hepcidin regulation

Disponibilidade de fósforo, cobre, manganes e zinco em três solos incubados com carbonato de cálcio.

Os solos tropicais são normalmente ácidos, devido a lixiviação de bases e ausência de minerais responsáveis pela reposição dessas bases (VITTI; PROCHNOW, 1996). Além da ocorrência natural, as práticas agrícolas de manejo podem acentuar a acidez do solo, Para Gama (1998) a recomendação correta de calcário tem grande importância, principalmente para que se tenhà uma adequada correção da acidez e aumente a eficiência dos fertilizantes. Isso torna-se mais relevante no caso do fósforo e dos micronutrientes metálicos, pois a acidez do solo exerce grande influência no controle da disponibilidade destes nutrientes. Segundo Lopes (1989) além da acidez, fatores como tipo e quantidade de argila do solo também influenciam a disponibilidade de P no mesmo. De acordo com Abreu et aI. (2001), o cobre tem sua disponibilidade controlada pela reação do solo e por altos teores de matéria orgânica que pode complexa-lo. No caso do manganês baixos teores naturais e o desequilíbrio de outros metais (Ca, Fe, Mg) condicionam a sua disponibilidade no solo (BORKET et al., 2001). Para estes autores a correção da acidez dos solos sob cerrados, com elevação da saturação por bases a 70% contribuiu para o surgimento de deficiências de manganês na cultura da soja, daí a recomendação atual de considerar 50% de saturação por bases como valor mais adequado àquela cultura. Quanto ao comportamento do zinco, Abreu et al.(200 1) relacionam que além da acidez baixa, altos teores de fósforo e matéria orgânica, podem reduzir a sua disponibilidade no solo. Esse trabalho teve como objetivo avaliar a disponibilidade de fósforo, cobre, manganês e zinco em três solos incubados com CaC03