786 research outputs found

    Apparatus for measuring thermal conductivity Patent

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    Development of apparatus for measuring thermal conductivit

    Sustainability assessment of high voltage transmission lines

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    This work aims to contribute to the proposal of a multi-criteria based methodology for sustainability evaluation of impacts from high voltage transmission lines integrating indicators reflecting environmental and socio-economic criteria. The proposed methodology was applied to a transmission grid project in Manaus/Amazonas, Brazil, evaluating its sustainability. From the analysis, it can be observed that the implementation of the project tends to have a significant impact during the construction phase. The most important indexes come from the environmental dimension resulting from a proximity to environmental protected areas and reduction of vegetation both during implementation and operation phases, which is particularly important for the case of Amazonia forest. As for the socio-economic index, this reflects an optimistic expectation of the population towards the arrival of electricity to communities that can lead to the creation of more jobs and improvement of cities infrastructures along with the low expected impact on local protected communities, given the previous studies addressing these concerns during the design phase. Based on the results achieved, avenues for future research are proposed.This work is financed by the ERDF – European Regional Development Fund through the Oper ational Programme for Competitiveness and Internationalisation COMPETE 2020 Programme, and by National Funds through the Portuguese funding agency, FCT Fundação para a Ciência e a Tecnologia, within project SAICTPAC/0004/2015-POCI/01/0145/FEDER/016434.as well as by the ALGORITMI research Centre POCI-01-0145-FEDER-007043 and FCT – Fundação para a Ciência e Tecnologia within the Project Scope: UID/CEC/00319/2013

    Low-level gas multicounter for C-14 dating of small samples: Electronic, numerical and shielding optimisation

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    Up to 14 methane samples can be dated simultaneously in our compact gas multicounter. Sample detectors are 10 ml (NTP) in volume each. They are made of copper and linked to form two 7 detector rigid assemblies which are filled in situ. Monitoring of the counting conditions is enabled through multichannel analysis of the cosmic pulse height spectrum, which shows the changes in gas amplification due to impurities or leakage. HV is set (and adjusted) automatically using the cosmic peak. All individual events are stored on disc, including pulse height (PH), risetime (RT) (both 256 Ch), time of arrival (TA), detector identification, anticoincidence status and elapsed and live time. Software programs analyse and validate data. Numerical discrimination and manipulations of counting parameters can be performed without destroying the original data set. Statistical quality control is based on chi-square and Poisson distribution of count rates around their mean in user defined energy regions as weil as time of arrival of pulses mode. TA analysis offers the user an early means for recognizing some types of system malfunction that otherwise might remain undetected for Jong periods of time. RT analysis is used to discriminate sample beta pulses from environmental radiation pulses, resulting in a low background with compact and relat ively inexpensive shielding. The automatic high voltage setting, PH, RT and TA electronics as weil as the liquid scintillation anticoincidence systems are applicable to all existing gas counting systems. Delivery of the gas multicounter to the Australian National University is to take place at the end of the year 1984

    Manganese superoxide dismutase as a diagnostic marker for malignant pleural mesothelioma

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    Although several immunohistochemical markers are available, differential diagnosis between mesothelioma and metastatic adenocarcinoma of the pleura is difficult. We have found that the immunoreactivity of manganese superoxide dismutase (MnSOD), an important antioxidant enzyme, is high in mesothelioma compared to healthy pleural mesothelium. The aim of the present study was to investigate whether MnSOD can be used in the differential diagnosis of malignant mesothelioma and metastatic adenocarcinoma of the pleura. MnSOD expression was assessed by using immunohistochemistry in biopsies of malignant mesothelioma (n = 35) and metastatic adenocarcinoma of the pleura (n = 21). MnSOD immunoreactivity was assessed semiquantitatively with and without microwave pretreatment. Fifteen of the 35 malignant mesotheliomas showed moderate or strong MnSOD expression without and 23 with microwave pretreatment, the corresponding figures for metastatic adenocarcinoma of the pleura being 1 and 2 out of 21 (P = 0.002 and P< 0.001, respectively by Fisher's exact test). Only mesothelioma biopsies showed strong MnSOD reactivity, and it was never negative in mesothelioma, whereas one-third of the adenocarcinomas showed no MnSOD reactivity. In conclusion, MnSOD immunoreactivity can, combined with other markers, aid the differential diagnosis between malignant mesothelioma and metastatic adenocarcinoma of the pleura. © 2000Cancer Research Campaig

    Finnish Pre-Service Teachers’ Perceptions of Perceived Competence in Early Childhood Physical Education

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    Early childhood education and care (ECEC) teachers have a central role in supporting young children’s physical activity (PA) and overall development in the early years. However, the value of early childhood education teacher training (ECETT) programmes is not widely understood. This study aimed to investigate pre-service teachers’ perceptions of perceived competence when (1) supporting a child’s PA, (2) teaching PE, and (3) observing and assessing a child’s motor skills and PA. These self-evaluations were compared with a range of individual, educational, and behavioural characteristics. Final-year Bachelor degree pre-service teachers (n = 274; 54%) from seven universities in Finland participated in the self-report questionnaire. The results of the linear regression models showed that the relevant PE studies and previous experiences of pre-service teachers predicted higher perceived competence of supporting a child’s PA, teaching PE, and observing and assessing a child’s motor skills and PA. Thus, the study findings demonstrated how teacher training could positively influence perceptions and attitudes to increase a person’s perceived competence when implementing PE in the early years. Overall, results reinforce the importance of PE in ECETT, and the time devoted to this syllabus area should be maintained or increased

    Expression of inducible nitric oxide synthase in healthy pleura and in malignant mesothelioma

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    In this study we investigated the immunohistochemical expression of inducible nitric oxide synthase (iNOS) in a set of normal pleural mesothelial tissues, malignant mesotheliomas, mesothelioma cell lines and metastatic pleural adenocarcinomas. Furthermore, the expression of mRNA was assessed in four malignant mesothelioma cell lines in culture. Apoptosis and vascular density in malignant mesotheliomas was assessed by the TUNEL method and by immunohistochemistry with an antibody against FVIII-related antigen. Immunohistochemically mesothelial cells in non-neoplastic healthy pleural tissues were mostly negative for iNOS. Positivity for iNOS was observed in 28/38 (74%) and 24/25 (96%) of malignant mesotheliomas and metastatic pleural adenocarcinomas, respectively. Epithelial and mixed mesotheliomas expressed more often strong iNOS immunoreactivity compared to the sarcomatoid subtype (P = 0.023). Moreover, metastatic adenocarcinomas expressed more often iNOS positivity than mesotheliomas (P = 0.021). Experiments with the cell lines confirmed that malignant mesothelioma cells are capable of synthesizing iNOS. No significant association was found between iNOS expression and apoptosis or vascular density in malignant mesotheliomas. The higher expression of iNOS in the epithelial subtype of mesothelioma and pleural metastatic adenocarcinoma might be due to an increased sensitivity of these cell types to cytokine-mediated iNOS upregulation. The strong expression of iNOS suggests a putative role for NO in the growth and progression of these tumours. © 2000 Cancer Research Campaig
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