Primary radiotherapy in progressive optic nerve sheath meningiomas: a long-term follow-up study

Background/aims: To report the outcome of primary radiotherapy in patients with progressive optic nerve sheath meningioma (ONSM). Methods: The clinical records of all patients were reviewed in a retrospective, observational, multicentre study. Results: Thirty-four consecutive patients were included. Twenty-six women and eight men received conventional or stereotactic fractionated radiotherapy, and were followed for a median 58 (range 51–156) months. Fourteen eyes (41%) showed improved visual acuity of at least two lines on the Snellen chart. In 17 (50%) eyes, the vision stabilised, while deterioration was noted in three eyes (9%). The visual outcome was not associated with age at the time of radiotherapy (p=0.83), sex (p=0.43), visual acuity at the time of presentation (p=0.22) or type of radiotherapy (p=0.35). Optic disc swelling was associated with improved visual acuity (p<0.01) and 4/11 patients with optic atrophy also showed improvement. Long-term complications were dry eyes in five patients, cataracts in three, and mild radiation retinopathy in four. Conclusion: Primary radiotherapy for patients with ONSM is associated with long-term improvement of visual acuity and few adverse effects.Peerooz Saeed, Leo Blank, Dinesh Selva, John G. Wolbers, Peter J.C.M. Nowak, Ronald B. Geskus, Ezekiel Weis, Maarten P. Mourits, Jack Rootma

Automated assembly of large double-sided microstrip detector modules of the CBM Silicon Tracking System at FAIR

The detector modules of the Silicon Tracking System of the Compressed Baryonic Matter experiment at FAIR comprise double-sided silicon microstrip sensors with a size of up to 124 mm x 62 mm. Due to tight material budget constraints, the sensors are connected to the read-out electronics by long flexible microcables. As manual assembly of the modules is time-consuming and difficult, a fully customized in-house bonder machine has been developed which allows for a highly automated detector module assembly. We present the requirements and the setup of the bonder machine together with the achieved alignment accuracy and first assemblies

Critical thickness and orbital ordering in ultrathin La0.7Sr0.3MnO3 films

Detailed analysis of transport, magnetism and x-ray absorption spectroscopy measurements on ultrathin La0.7Sr0.3MnO3 films with thicknesses from 3 to 70 unit cells resulted in the identification of a lower critical thickness for a non-metallic, non-ferromagnetic layer at the interface with the SrTiO3 (001) substrate of only 3 unit cells (~12 Angstrom). Furthermore, linear dichroism measurements demonstrate the presence of a preferred (x2-y2) in-plane orbital ordering for all layer thicknesses without any orbital reconstruction at the interface. A crucial requirement for the accurate study of these ultrathin films is a controlled growth process, offering the coexistence of layer-by-layer growth and bulk-like magnetic/transport properties.Comment: 22 pages, 6 figures, accepted for publication in Physical Review

Chaotic Cascades with Kolmogorov 1941 Scaling

We define a (chaotic) deterministic variant of random multiplicative cascade models of turbulence. It preserves the hierarchical tree structure, thanks to the addition of infinitesimal noise. The zero-noise limit can be handled by Perron-Frobenius theory, just as the zero-diffusivity limit for the fast dynamo problem. Random multiplicative models do not possess Kolmogorov 1941 (K41) scaling because of a large-deviations effect. Our numerical studies indicate that deterministic multiplicative models can be chaotic and still have exact K41 scaling. A mechanism is suggested for avoiding large deviations, which is present in maps with a neutrally unstable fixed point.Comment: 14 pages, plain LaTex, 6 figures available upon request as hard copy (no local report #

On the discovery of doubly-magic 48^{48}Ni

The paper reports on the first observation of doubly-magic Nickel-48 in an experimental at the SISSI/LISE3 facility of GANIL. Four Nickel-48 isotopes were identified. In addition, roughly 100 Nickel-49, 50 Iron-45, and 290 Chromium-42 isotopes were observed. This opens the possibility to search for two-proton emission from these nuclei.Comment: 4 pages, 3 figures, accepted for publication in Phys. Rev. Let

The non-self-adjointness of the radial momentum operator in n dimensions

The non self-adjointness of the radial momentum operator has been noted before by several authors, but the various proofs are incorrect. We give a rigorous proof that the $n$-dimensional radial momentum operator is not self- adjoint and has no self-adjoint extensions. The main idea of the proof is to show that this operator is unitarily equivalent to the momentum operator on $L^{2}[(0,\infty),dr]$ which is not self-adjoint and has no self-adjoint extensions.Comment: Some text and a reference adde