Opposite Sex Friendship Initiation: Dispositional Differences in Self-Monitoring

Based on the self-monitoring and friendship literature (Fuglestad & Snyder, 2010) it was predicted that compared to low self-monitors, high self-monitors have an unrestricted orientation to sexual liaisons and view friendships as activity-based. These two tendencies suggest high self-monitors are more likely than low self-monitors to initiate opposite sex friendships for sexual purposes whereas low self-monitors are more likely than high self-monitors to initiate opposite sex friendships for companionship purposes. To evaluate this prediction, 133 male and 135 female heterosexuals completed the 25 item Self-Monitoring Scale (Snyder, 1974), the Reasons for Friendship Initiation Scale (Bleske-Rechek & Buss, 2001), and the Sociosexual Orientation Inventory (Simpson & Gangestad, 1991; Penke & Aspendorf, 2008). While controlling for sociosexuality, high self-monitors more often than low self-monitors initiated opposite sex friendships for sexual gratification, while there was no significant relationship between self-monitoring and companionship. Limitations (e.g., nonexperimental design, self-report, unrepresentative sample), and future directions (e.g., longitudinal designs, behavioral observations, diverse samples) are discussed

hnRNP K: An HDM2 Target and Transcriptional Coactivator of p53 in Response to DNA Damage

SummaryIn response to DNA damage, mammalian cells trigger the p53-dependent transcriptional induction of factors that regulate DNA repair, cell-cycle progression, or cell survival. Through differential proteomics, we identify heterogeneous nuclear ribonucleoprotein K (hnRNP K) as being rapidly induced by DNA damage in a manner that requires the DNA-damage signaling kinases ATM or ATR. Induction of hnRNP K ensues through the inhibition of its ubiquitin-dependent proteasomal degradation mediated by the ubiquitin E3 ligase HDM2/MDM2. Strikingly, hnRNP K depletion abrogates transcriptional induction of p53 target genes and causes defects in DNA-damage-induced cell-cycle-checkpoint arrests. Furthermore, in response to DNA damage, p53 and hnRNP K are recruited to the promoters of p53-responsive genes in a mutually dependent manner. These findings establish hnRNP K as a new HDM2 target and show that, by serving as a cofactor for p53, hnRNP K plays key roles in coordinating transcriptional responses to DNA damage

Notes: Evaluation Of A Filter Bag System For NDF, ADF, And IVDMD Forage Analysis

A new method of determining in vitro dry matter digestibility (IVDMD) as recently developed in which the digestion is conducted with the forage samples in filter bags. Our objective was to compare the filter bag and conventional IVDMD analysis methods using smooth bromegrass (Bromus inermis Leyss.), switchgrass (Panicum virgatum L.), and forage sorghum [Sorghum bicolor (L.) Moench] samples. In addition, the filter bag analysis systems for determining non-sequential neutral and acid detergent fiber (NDF and ADF), respectively, were compared with the non-sequential conventional analysis systems. In the filter bag systems, the forage samples are sealed in filter bags and the analyses are conducted on a batch basis rather than on an individual basis as in the conventional IVDMD and fiber analysis procedures. The filter bag analysis methods produced results similar to the conventional methods and ranked the forage samples in the same relative order

Notes: Evaluation Of A Filter Bag System For NDF, ADF, And IVDMD Forage Analysis

A new method of determining in vitro dry matter digestibility (IVDMD) as recently developed in which the digestion is conducted with the forage samples in filter bags. Our objective was to compare the filter bag and conventional IVDMD analysis methods using smooth bromegrass (Bromus inermis Leyss.), switchgrass (Panicum virgatum L.), and forage sorghum [Sorghum bicolor (L.) Moench] samples. In addition, the filter bag analysis systems for determining non-sequential neutral and acid detergent fiber (NDF and ADF), respectively, were compared with the non-sequential conventional analysis systems. In the filter bag systems, the forage samples are sealed in filter bags and the analyses are conducted on a batch basis rather than on an individual basis as in the conventional IVDMD and fiber analysis procedures. The filter bag analysis methods produced results similar to the conventional methods and ranked the forage samples in the same relative order

The development of advanced practice roles: implications in the international nursing community

This article examined the critical elements that have been identified in the development of advanced practice roles of nurses in four countries: Brazil, Thailand, the United Kingdom and the United States of America. Several socio-political and professional forces were examined for possible insights and ways in which they may have shaped the development and evolution of the roles of advanced practice nurses (APNs). These forces were: the socio-political environment; the health needs of society; the health workforce supply and demand; governmental policy and support; intra- and interprofessional collaboration; the development of nursing education; and documentation of effectiveness of the advanced role. The development of APN roles in the four social systems was reviewed to illustrate how socio-political and professional forces may have shaped nursing roles in each health care delivery system. Commonalities and distinguishing features across the four health and social systems were analysed to assess the predictive forces that may be identified as advanced roles in nursing have evolved in the global community.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74797/1/j.1466-7657.2001.00065.x.pd

Mineral Element Analyses of Switchgrass Biomass: Comparison of the Accuracy and Precision of Laboratories

Mineral concentration of plant biomass can affect its use in thermal conversion to energy. The objective of this study was to compare the precision and accuracy of university and private laboratories that conduct mineral analyses of plant biomass on a fee basis. Accuracy and precision of the laboratories was tested by having all laboratories conduct mineral analyses on subsamples of the same set of standard switchgrass (Panicum virgatum L.) samples and a certified standard. Laboratories differed significantly in both accuracy and precision even though several used the same analysis method indicating that the differences among laboratories were due to within laboratory procedures and quality control. Laboratories should be using sample standards to monitor both precision and accuracy of their mineral analyses. It would be advisable for researchers submitting samples to service laboratories to replicate the unknown samples to determine precision and to include replicated standards among the submitted samples to determine accuracy

Modeling the Influence of a Variable Permeability Inclusion on Free-Surface Flow in an Inclined Aquifer

The interaction of sub-surface, gravity-driven flows with inclusions of different permeabilities are investigated theoretically using a model that exploits the relative shallowness of the motion. Numerically computed solutions for steady motion around cylindrical inclusions reveal a range of behaviors dependent on the ratio of the interior to exterior permeability and a dimensionless flow parameter that measures the far-field thickness to the product of the gradient of the slope down which the fluid flows and the width of the inclusion. When the inclusion is relatively narrow, the depth of the flow is little changed from its far-field value and the fluid is focused into inclusions of higher permeability and deflected around those of lower permeability. However, if the inclusion is relatively wide then three qualitatively different regimes emerge, dependent on the ratio of permeabilities. When the interior and exterior permeabilities are similar, then negligible deviation of the flow occurs apart from within thin transition layers at the boundary of the inclusion. When the permeabilities differ significantly, the flow forms deep ponds at either the upstream or downstream boundary of the inclusion for relatively low or high permeability inclusion, respectively, which arise due to deflection or focusing. In each case, asymptotic relationships are derived between the depth of the flow and the parameters. Inclusions of differing cross-section are also analyzed numerically and analytically to draw out the interplay between adjustment, deflection and focusing

Design and Test of a Deployable Radiation Cover for the REgolith X-Ray Imaging Spectrometer

The REgolith X-ray Imaging Spectrometer (REXIS) instrument contains a one-time deployable radiation cover that is opened using a shape memory alloy actuator (a "Frangibolt") from TiNi Aerospace and two torsion springs. The door will be held closed by the bolt for several years in cold storage during travel to the target asteroid, Bennu, and it is imperative to gain confidence that the door will open at predicted operational temperatures. This paper briefly covers the main design features of the radiation cover and measures taken to mitigate risks to cover deployment. As the chosen FD04 model Frangibolt actuator has minimal flight heritage, the main focus of this paper is the testing, results and conclusions with the FD04 while discussing key lessons learned with respect to the use of the FD04 actuator in this application

Bridging groundwater models and decision support with a Bayesian network

Author Posting. © American Geophysical Union, 2013. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Water Resources Research 49 (2013): 6459–6473, doi:10.1002/wrcr.20496.Resource managers need to make decisions to plan for future environmental conditions, particularly sea level rise, in the face of substantial uncertainty. Many interacting processes factor in to the decisions they face. Advances in process models and the quantification of uncertainty have made models a valuable tool for this purpose. Long-simulation runtimes and, often, numerical instability make linking process models impractical in many cases. A method for emulating the important connections between model input and forecasts, while propagating uncertainty, has the potential to provide a bridge between complicated numerical process models and the efficiency and stability needed for decision making. We explore this using a Bayesian network (BN) to emulate a groundwater flow model. We expand on previous approaches to validating a BN by calculating forecasting skill using cross validation of a groundwater model of Assateague Island in Virginia and Maryland, USA. This BN emulation was shown to capture the important groundwater-flow characteristics and uncertainty of the groundwater system because of its connection to island morphology and sea level. Forecast power metrics associated with the validation of multiple alternative BN designs guided the selection of an optimal level of BN complexity. Assateague island is an ideal test case for exploring a forecasting tool based on current conditions because the unique hydrogeomorphological variability of the island includes a range of settings indicative of past, current, and future conditions. The resulting BN is a valuable tool for exploring the response of groundwater conditions to sea level rise in decision support.This work was funded by the USGS Climate and Land Use Mission Area, Research and Development Program and the USGS Natural Hazards Mission Area, Coastal and Marine Geology Program