Pregnancy related back pain, is it related to aerobic fitness? A longitudinal cohort study

<p>Abstract</p> <p>Background</p> <p>Low back pain with onset during pregnancy is common and approximately one out of three women have disabling pain. The pathogenesis of the pain condition is uncertain and there is no information on the role of physical fitness. Whether poorer physical conditioning is a cause or effect of back pain is also disputed and information from prospective studies needed.</p> <p>Methods</p> <p>A cohort of pregnant women, recruited from maternal health care centers in central Sweden, were examined regarding estimated peak oxygen uptake by cycle ergometer test in early pregnancy, reported physical activity prior to pregnancy, basic characteristics, back pain during pregnancy and back pain postpartum.</p> <p>Results</p> <p>Back pain during the current pregnancy was reported by nearly 80% of the women. At the postpartum appointment this prevalence was 40%. No association was displayed between estimated peak oxygen uptake and incidence of back pain during and after pregnancy, adjusted for physical activity, back pain before present pregnancy, previous deliveries, age and weight. A significant inverse association was found between estimated peak oxygen uptake and back pain intensity during pregnancy and a direct association post partum, in a fully adjusted multiple linear regression analysis.</p> <p>Conclusions</p> <p>Estimated peak oxygen uptake and reported physical activity in early pregnancy displayed no influence on the onset of subsequent back pain during or after pregnancy, where the time sequence support the hypothesis that poorer physical deconditioning is not a cause but a consequence of the back pain condition. The mechanism for the attenuating effect of increased oxygen uptake on back pain intensity is uncertain.</p

Photon capture cones and embedding diagrams of the Ernst spacetime

The differences between the character of the Schwarzschild and Ernst spacetimes are illustrated by comparing the photon capture cones, and the embedding diagrams of the $t=\mathrm{const}$ sections of the equatorial planes of both the ordinary and optical reference geometry of these spacetimes. The non-flat asymptotic character of the Ernst spacetime reflects itself in two manifest facts: the escape photon cones correspond to purely outward radial direction, and the embedding diagrams of both the ordinary and optical geometry shrink to zero radius asymptotically. Using the properties of the embedding diagrams, regions of these spacetimes which could have similar character are estimated, and it is argued that they can exist for the Ernst spacetimes with a sufficiently low strength of the magnetic field.Comment: 12 pages, 7 figure

An Exact Solution of 4D Higher-Spin Gauge Theory

We give a one-parameter family of exact solutions to four-dimensional higher-spin gauge theory invariant under a deformed higher-spin extension of SO(3,1) and parameterized by a zero-form invariant. All higher-spin gauge fields vanish, while the metric interpolates between two asymptotically AdS4 regions via a dS3-foliated domainwall and two H3-foliated Robertson-Walker spacetimes -- one in the future and one in the past -- with the scalar field playing the role of foliation parameter. All Weyl tensors vanish, including that of spin two. We furthermore discuss methods for constructing solutions, including deformation of solutions to pure AdS gravity, the gauge-function approach, the perturbative treatment of (pseudo-)singular initial data describing isometric or otherwise projected solutions, and zero-form invariants.Comment: 47 pages. v3: global properties of the solution clarified, minor corrections made, discussion and refs revise

Approximate reasoning with fuzzy-syllogistic systems

The well known Aristotelian syllogistic system consists of 256 moods. We have found earlier that 136 moods are distinct in terms of equal truth ratios that range in τ=[0,1]. The truth ratio of a particular mood is calculated by relating the number of true and false syllogistic cases the mood matches. A mood with truth ratio is a fuzzy-syllogistic mood. The introduction of (n-1) fuzzy existential quantifiers extends the system to fuzzy-syllogistic systems nS, 1<n, of which every fuzzy-syllogistic mood can be interpreted as a vague inference with a generic truth ratio that is determined by its syllogistic structure. We experimentally introduce the logic of a fuzzy-syllogistic ontology reasoner that is based on the fuzzy-syllogistic systems nS. We further introduce a new concept, the relative truth ratio rτ=[0,1] that is calculated based on the cardinalities of the syllogistic cases

Gait in Pregnancy-related Pelvic girdle Pain: amplitudes, timing, and coordination of horizontal trunk rotations

Walking is impaired in Pregnancy-related Pelvic girdle Pain (PPP). Walking velocity is reduced, and in postpartum PPP relative phase between horizontal pelvis and thorax rotations was found to be lower at higher velocities, and rotational amplitudes tended to be larger. While attempting to confirm these findings for PPP during pregnancy, we wanted to identify underlying mechanisms. We compared gait kinematics of 12 healthy pregnant women and 12 pregnant women with PPP, focusing on the amplitudes of transverse segmental rotations, the timing and relative phase of these rotations, and the amplitude of spinal rotations. In PPP during pregnancy walking velocity was lower than in controls, and negatively correlated with fear of movement. While patients’ rotational amplitudes were larger, with large inter-individual differences, spinal rotations did not differ between groups. In the patients, peak thorax rotation occurred earlier in the stride cycle at higher velocities, and relative phase was lower. The earlier results on postpartum PPP were confirmed for PPP during pregnancy. Spinal rotations remained unaffected, while at higher velocities the peak of thorax rotations occurred earlier in the stride cycle. The latter change may serve to avoid excessive spine rotations caused by the larger segmental rotations

Scalar Field Corrections to AdS_4 Gravity from Higher Spin Gauge Theory

We compute the complete contribution to the stress-energy tensor in the minimal bosonic higher spin theory in D=4 that is quadratic in the scalar field. We find arbitrarily high derivative terms, and that the total sign of the stress-energy tensor depends on the parity of the scalar field.Comment: 15 pages + appendix (30 pages

Genome-wide analysis of nuclear magnetic resonance metabolites revealed parent-of-origin effect on triglycerides in medium very low-density lipoprotein in PTPRD gene

The aim of the study was to explore the parent-of-origin effects (POEs) on a range of human nuclear magnetic resonance metabolites. Materials & methods: We search for POEs in 14,815 unrelated individuals from Estonian and Finnish cohorts using POE method for the genotype data imputed with 1000 G reference panel and 82 nuclear magnetic resonance metabolites. Results: Meta-analysis revealed the evidence of POE for the variant rs1412727 in PTPRD gene for the metabolite: triglycerides in medium very low-density lipoprotein. No POEs were detected for genetic variants that were previously known to have main effect on circulating metabolites. Conclusion: We demonstrated possibility to detect POEs for human metabolites, but the POEs are weak, and therefore it is hard to detect those using currently available sample sizes.Peer reviewe