Underlying symmetries of realistic interactions and the nuclear many-body problem

The present study brings forward important information, within the framework of spectral distribution theory, about the types of forces that dominate three realistic interactions, CD-Bonn, CDBonn+ 3terms and GXPF1, in nuclei and their ability to account for many-particle effects such as the formation of correlated nucleon pairs and enhanced quadrupole collective modes. Like-particle and proton-neutron isovector pairing correlations are described microscopically by a model interaction with Sp(4) dynamical symmetry, which is extended to include an additional quadrupole-quadrupole interaction. The analysis of the results for the 1f7/2 level shows that both CD-Bonn+3terms and GXPF1 exhibit a well-developed pairing character compared to CD-Bonn, while the latter appears to build up more (less) rotational isovector T = 1 (isoscalar T = 0) collective features. Furthermore, the three realistic interactions are in general found to correlate strongly with the pairing+quadrupole model interaction, especially for the highest possible isospin group of states where the model interaction can be used to provide a reasonable description of the corresponding energy spectra.Comment: 12 pages, 4 figure

The development of methods for the early identification of heart disease and related job stresses Progress report, 1 Mar. - 30 Jun. 1969

Methods for early identification of heart disease and related job stresse

U(3) and Pseudo-U(3) Symmetry of the Relativistic Harmonic Oscillator

We show that a Dirac Hamiltonian with equal scalar and vector harmonic oscillator potentials has not only a spin symmetry but an U(3) symmetry and that a Dirac Hamiltonian with scalar and vector harmonic oscillator potentials equal in magnitude but opposite in sign has not only a pseudospin symmetry but a pseudo-U(3) symmetry. We derive the generators of the symmetry for each case.Comment: 8 pages, 0 figures, pusblished in Physical Review Letters 95, 252501 (2005

Photic effects on sustained performance

Research is described which evaluates manipulating environmental light intensity as a means to attenuate fatigue. A counter balanced, within-subjects design was used to compare nine male subjects exposed to dim (100 lux) and bright (3000 lux) light conditions. Oral temperature values were greater for the bright light group over the dim light condition. Melatonin levels were suppressed by bright light treatment. Also, the frequency of eye blink rate was less for subjects during bright over dim light exposure. Light exposure was without effect on subjective fatigue. However, irrespective of light condition, significant effects on confusion, fatigue, and vigor mood dimensions were found as a result of 30 hour sleep deprivation. The findings suggest that bright lights may be used to help sustain nocturnal activity otherwise susceptible to fatigue. Such findings may have implications for the lighting arrangements on space flights during the subjective night for astronauts

Clustering of equine grass sickness cases in the United Kingdom: a study considering the effect of position-dependent reporting on the space-time K-function

Equine grass sickness (EGS) is a largely fatal, pasture-associated dysautonomia. Although the aetiology of this disease is unknown, there is increasing evidence that Clostridium botulinum type C plays an important role in this condition. The disease is widespread in the United Kingdom, with the highest incidence believed to occur in Scotland. EGS also shows strong seasonal variation (most cases are reported between April and July). Data from histologically confirmed cases of EGS from England and Wales in 1999 and 2000 were collected from UK veterinary diagnostic centres. The data did not represent a complete census of cases, and the proportion of all cases reported to the centres would have varied in space and, independently, in time. We consider the variable reporting of this condition and the appropriateness of the space–time K-function when exploring the spatial-temporal properties of a ‘thinned’ point process. We conclude that such position-dependent under-reporting of EGS does not invalidate the Monte Carlo test for space–time interaction, and find strong evidence for space–time clustering of EGS cases (P<0.001). This may be attributed to contagious or other spatially and temporally localized processes such as local climate and/or pasture management practices

Semi-automatic selection of summary statistics for ABC model choice

A central statistical goal is to choose between alternative explanatory models of data. In many modern applications, such as population genetics, it is not possible to apply standard methods based on evaluating the likelihood functions of the models, as these are numerically intractable. Approximate Bayesian computation (ABC) is a commonly used alternative for such situations. ABC simulates data x for many parameter values under each model, which is compared to the observed data xobs. More weight is placed on models under which S(x) is close to S(xobs), where S maps data to a vector of summary statistics. Previous work has shown the choice of S is crucial to the efficiency and accuracy of ABC. This paper provides a method to select good summary statistics for model choice. It uses a preliminary step, simulating many x values from all models and fitting regressions to this with the model as response. The resulting model weight estimators are used as S in an ABC analysis. Theoretical results are given to justify this as approximating low dimensional sufficient statistics. A substantive application is presented: choosing between competing coalescent models of demographic growth for Campylobacter jejuni in New Zealand using multi-locus sequence typing data

Duality Between the Weak and Strong Interaction Limits for Randomly Interacting Fermions

We establish the existence of a duality transformation for generic models of interacting fermions with two-body interactions. The eigenstates at weak and strong interaction U possess similar statistical properties when expressed in the U=0 and U=infinity eigenstates bases respectively. This implies the existence of a duality point U_d where the eigenstates have the same spreading in both bases. U_d is surrounded by an interval of finite width which is characterized by a non Lorentzian spreading of the strength function in both bases. Scaling arguments predict the survival of this intermediate regime as the number of particles is increased.Comment: RevTex4, 4 pages, 4 figures. Accepted for publication at Phys. Rev. Let

Novel 3D imaging platform tracks cancer progression in vivo

Optical imaging underpins biomedical research in many respects and recent decades have seen spectacular advances, particularly in fluorescence imaging where genetic engineering approaches to labelling have been combined with new light sources, detectors and data analysis techniques to provide capabilities like super-resolution beyond the diffraction limit, exquisite spectroscopic contrast for molecular readouts and high-speed image capture for in vivo and high-throughput applications. However, the main impact of such advanced instrumentation and data analysis has been to provide unprecedented quantitative 2D and 3D information concerning samples compatible with microscopy where volumes of less than 1 mm3 are typically imaged in a single 'acquisition'. The ability to view and measure cellular processes and signalling pathways in live cells has been a significant advance for biomedical research and drug discovery. However, for conventional microscope-based assays and experiments, the samples typically comprise thin layers of cells that are not experiencing the same signals that they would in a 3D tissue context and any findings may not directly translate to live organisms. It is desirable to study disease processes in live intact organisms that can provide appropriate physiological complexity. For cancer studies, recent research from our group shows that optical tomography can be used to directly monitor in vivo changes in tumour growth and vascular development in a zebrafish cancer model over time. This technique not only improves the value of the collected data, but if used on a wider scale should result in a reduction in the number of animals used in biomedical research

Influence of American Institutions on Information Systems (IS) Research within Asia

As the world continues to globalize, business and academia have begun to take a different form of response to these changes. No longer are researchers restricted to localized education or publication outlets. Journals publications, methods used, and topics researched are heavily influenced by the training researchers receive during their doctoral program. Research conducted in Asia has displayed a strong influence from western culture resulting from top researchers at business schools in Asia obtaining their terminal degrees in the North America. However, Asian research appears entangled between developing theory in local context and international requirements for publication. The current research evaluates the educational background influencing top researchers throughout Asia. A discussion of the implications due to Western influence on Asia is provided along with recommendations for knowledge sharing and increasing diversity among from a multinational and global perspective. Available at: https://aisel.aisnet.org/pajais/vol4/iss4/4

Gamma-ray bursts and X-ray melting of material as a potential source of chondrules and planets

The intense radiation from a gamma-ray burst (GRB) is shown to be capable of melting stony material at distances up to 300 light years which subsequently cool to form chondrules. These conditions were created in the laboratory for the first time when millimeter sized pellets were placed in a vacuum chamber in the white synchrotron beam at the European Synchrotron Radiation Facility (ESRF). The pellets were rapidly heated in the X-ray and gamma-ray furnace to above 1400 C melted and cooled. This process heats from the inside unlike normal furnaces. The melted spherical samples were examined with a range of techniques and found to have microstructural properties similar to the chondrules that come from meteorites. This experiment demonstrates that GRBs can melt precursor material to form chondrules that may subsequently influence the formation of planets. This work extends the field of laboratory astrophysics to include high power synchrotron sources.Comment: 8 pages, 10 figures. Proceedings of the 5th INTEGRAL Workshop, Munich 16-20 February 2004. High resolution figures available at http://bermuda.ucd.ie/%7Esmcbreen/papers/duggan_01.pd