35,717 research outputs found

    Symbolic framework for linear active circuits based on port equivalence using limit variables

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    Reply to the comment by Carmelo Anile on the paper "Complexity analysis of the cerebrospinal fluid pulse waveform during infusion studies"

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    Veterinary technology is an emerging profession within the veterinary and allied animal health fields in Australia and affords graduates the opportunity to contribute to the small but growing body of literature within this discipline. This study describes the introduction of a contextualised assessment task to develop students’ research capability, competence and confidence in professional writing, and to engage them with the academic publishing process. Students worked in self-selected dyads to author a scientific case report, of publishable standard, based on authentic cases from their clinical practicum. Intrinsic to the task, students attended a series of workshops that explored topics such as critiquing the literature, professional writing styles and oral presentation skills. Assessment was multi-staged with progressive feedback, including peer review, and culminated with students presenting their abstracts at a mock conference. Students reported the task to be an enjoyable and valuable learning experience which improved their competence and confidence in scientific writing; supported by a comparison of previously submitted work. Linking scientific writing skills to clinical practice experiences enhanced learning outcomes and may foster the professionalisation of students within this emerging discipline

    New tools in comparative political economy: The database of political institutions.

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    [Dataset available: http://hdl.handle.net/10411/15987]

    Deconfined Fermions but Confined Coherence?

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    The cuprate superconductors and certain organic conductors exhibit transport which is qualitatively anisotropic, yet at the same time other properties of these materials strongly suggest the existence of a Fermi surface and low energy excitations with substantial free electron character. The former of these features is very difficult to account for if the material possesses three dimensional coherence, while the latter is inconsistent with a description based on a two dimensional fixed point. We therefore present a new proposal for these materials in which they are categorized by a fixed point at which transport in one direction is not renormalization group irrelevant, but is intrinsically incoherent, i.e. the incoherence is present in a pure system, at zero temperature. The defining property of such a state is that single electron coherence is confined to lower dimensional subspaces (planes or chains) so that it is impossible to observe interference effects between histories which involve electrons moving between these subspaces.Comment: 31 pages, REVTEX, 3 eps figures, epsf.tex macr

    Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme.

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    Most biodiesel currently in use consists of fatty acid methyl esters (FAMEs) produced by transesterification of plant oils with methanol. To reduce competition with food supplies, it would be desirable to directly produce biodiesel in microorganisms. To date, the most effective pathway for the production of biodiesel in bacteria yields fatty acid ethyl esters (FAEEs) at up to ~1.5 g/L. A much simpler route to biodiesel produces FAMEs by direct S-adenosyl-L-methionine (SAM) dependent methylation of free fatty acids, but FAME production by this route has been limited to only ~16 mg/L. Here we employ an alternative, broad spectrum methyltransferase, Drosophila melanogaster Juvenile Hormone Acid O-Methyltransferase (DmJHAMT). By introducing DmJHAMT in E. coli engineered to produce medium chain fatty acids and overproduce SAM, we obtain medium chain FAMEs at titers of 0.56 g/L, a 35-fold increase over titers previously achieved. Although considerable improvements will be needed for viable bacterial production of FAMEs and FAEEs for biofuels, it may be easier to optimize and transport the FAME production pathway to other microorganisms because it involves fewer enzymes

    A Bioeconomic Analysis of the Northwestern Hawaiian Islands Lobster Fishery

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    Several surplus production-based bioeconomic models are applied to the Northwestern Hawaiian Islands (NWHI) commercial lobster fishery. The model which best explains the biological dynamics of the fishery is a modification of the Fox model developed by the authors. Economic costs are applied within a number of conceptual frameworks to develop the first integrated bioeconomic model of the fishery. In another development, the opportunity cost of labor based on crew share at the open access equilibrium level of fishing effort is used instead of proxy wage levels. Given the costs incurred, the fishery appears to be self-regulating in terms of long-term fishing effort for maximum sustainable yield.biological production models, fisheries economics, fisheries management, spiny lobster, slipper lobster, Environmental Economics and Policy, Resource /Energy Economics and Policy,

    Parcellation: A hard theory to test

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    Visual motion-evoked potentials in man

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    Visual motion-evoked potentials were recorded from the human scalp. The stimulus chosen for most detailed study was sudden reversal of the motion of a patterned field, on the hypothesis that this was likely to activate only mechanisms selectively sensitive to the direction of stimulus motion. A large proportion of the experiments were designed to test this hypothesis; and in fact they supported it. In addition to motion-reversal VEPs, VEPs to the onset and the offset of pattern motion, and to the appearance and disappearance of patterns were recorded and analysed. The relationships between these different types of VEP were investigated. Also, the dependence of the motion-onset, -offset end -reversal VEPs on certain stimulus parameters was studied. Are motion-reversal VEPs produced by direction-selective mechanisms? That direction-selective mechanisms were at least partly responsible for the motion-reversal VEPs was confirmed, since an adapting stimulus moving in the same direction as the motion before reversal produced an effect on the VEP different to that produced by en adapting stimulus moving in the opposite direction. Further investigation indicated that direction-selective mechanisms were probably the sole contributors to the motion-reversal VEPs, since control experiments failed to support any of the most likely alternative ways in which direction-insensitive mechanisms might theoretically have contributed to the motion-reversal VEPs. In particular, considerable attention was devoted to the possibility that mechanisms sensitive to contrast but insensitive to direction of motion might have been activated by a brief increase in the effective contrast of the stimulus pattern at the moment of reversal, and thereby have contributed to the VEP. Such an increase in the effective contrast could in theory have been caused by the brief slowing down which inevitably occurred at the moment of reversal, but several experiments refuted this interpretation. In particular, the VEPs were virtually independent of the time taken for reversal, but were very dependent on the velocity before and after reversal, reducing almost to zero at very high or very low velocities. A sudden step-displacement or change of the pattern at the moment of reversal suppressed the VEP. This effect was not caused by interference with the time-course of slow movement at reversal, since suppression occurred even when the step-displacement took place outside the period of slow movement. A psychophysical effect has been observed which may be connected with this phenomenon. Involuntary eye movements ere apparent~ not implicated in the production of the VEPs, since periodic and aperiodic stimulation yield similar results. Certain other ways in which VEP components might have arisen, even in the absence of eye movements or imperfections in the stimulus motion, have been investigated; but there has been no indication of the occurrence of such components. So the motion-reversal VEPs probably arose almost entirely from direction-selective mechanisms. Component analysis of VEPs The VEPs to the reversal and to the offset of motion apparently comprised three separate component peaks. In this respect they were similar to pattern-appearance VEPs, and the distribution over the scalp of any one of the components was the same for all three kinds of VEP (e.g. the first peak of the motion-reversal VEP had the some scalp-distribution as the first peak of the motion-offset VEP and the first peak of the pattern-appearance VEP). This implied that the corresponding components originated in the same cortical areas, and a correlation analysis of the amplitudes of the various components of motion-reversal VEPs and pattern-appearance VEPs for different subjects supported this conclusion. Now there is convincing evidence (Jeffreys, 1971) that the first component of pattern-appearance VEPs originates in striate cortex end the later components in extrastriate cortex. It is therefore concluded that the first peaks of motion-reversal and. motion-offset VEPs are likewise probably from striate cortex, and the later peaks from extrastriate. The VEP to motion-onset was very different from the above VEPs, however, and appeared to be more closely related to the pattern-disappearance VEP. It is possible that the same mechanisms underlie these two kinds of VEP. Although motion-reversal VEPs appear to be the product of direction-selective mechanisms alone, it is far from certain that this is true of motion-onset and -offset VEPs. Nevertheless, there is evidence that the latter kinds of VEP may share generating mechanisms with the former; since the motion-reversal VEP was, under many conditions though not all, a good approximation to the sum of the motion-onset and -offset VEPs recorded under similar stimulus conditions. The effects of varying stimulus parameters Motion-reversal VEPs were found to be largely independent of brightness except at the lowest levels, but the latency did tend to increase slightly as the brightness was reduced. Despite the discovery (MaCKay & Rietveld, 1968) that the proximity of a stationary reference line enhances the VEP to the onset of motion of a stimulus line,' it appears that the sharp contours comprising the edge of the visual field did not influence the VEPs to the onset, offset or reversal of pattern motion, since replacing the sharp contours by blurred ones did not affect the VEPs. The onset, offset and reversal VEPs did not depend greatly on the direction of motion. Superimposing a steady motion did, however, markedly modify the VEPs. The effects of using patterns other than visual noise were investigated. Checkerboards and visual noise produced similar results, but line rasters produced very different VEPs

    Creating citizen-consumers? Public service reform and (un)willing selves

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    About the book: Postmodern theories heralded the "death of the subject", and thereby deeply contested our intuition that we are free and willing selves. In recent times, the (free) will has come under attack yet again. Findings from the neuro- and cognitive sciences claim the concept of will to be scientifically untenable, specifying that it is our brain rather than our 'self' which decides what we want to do. In spite of these challenges however, the willing self has come to take centre stage in our society: juridical and moral practices ascribing guilt, or the organization of everyday life attributing responsibilities, for instance, can hardly be understood without taking recourse to the willing subject. In this vein, the authors address topics such as the genealogy of the concept of willing selves, the discourse on agency in neuroscience and sociology, the political debate on volition within neoliberal and neoconservative regimes, approaches toward novel forms of relational responsibility as well as moral evaluations in conceptualizing autonomy
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