678 research outputs found

    Finite-temperature properties of frustrated classical spins coupled to the lattice

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    We present extensive Monte Carlo simulations for a classical antiferromagnetic Heisenberg model with both nearest (J1J_1) and next-nearest (J2J_2) exchange couplings on the square lattice coupled to the lattice degrees of freedom. The Ising-like phase transition, that appears for J2/J1>1/2J_2/J_1>1/2 in the pure spin model, is strengthened by the spin-lattice coupling, and is accompanied by a lattice deformation from a tetragonal symmetry to an orthorhombic one. Evidences that the universality class of the transition does not change with the inclusion of the spin-lattice coupling are reported. Implications for Li2VOSiO4{\rm Li_2VOSiO_4}, the prototype for a layered J1J2J_1{-}J_2 model in the collinear regime, are also discussed.Comment: 6 pages and 8 figure

    Ising transition driven by frustration in a 2D classical model with SU(2) symmetry

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    We study the thermal properties of the classical antiferromagnetic Heisenberg model with both nearest (J1J_1) and next-nearest (J2J_2) exchange couplings on the square lattice by extensive Monte Carlo simulations. We show that, for J2/J1>1/2J_2/J_1 > 1/2 , thermal fluctuations give rise to an effective Z2Z_2 symmetry leading to a {\it finite-temperature} phase transition. We provide strong numerical evidence that this transition is in the 2D Ising universality class, and that Tc0T_c\to 0 with an infinite slope when J2/J11/2J_2/J_1\to 1/2.Comment: 4 pages with 4 figure

    Os jovens na "era do jazz" ou "os belos e os malditos"

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    Os anos vinte foram anos de grande bulício e agitação em todas as esferas da vida social, cultural, económica e política. Porém, nenhum aspecto foi tão comentado e tratado com auras de maior sensacionalismo do que a dita revolta dos jovens: uma simples alusão aos anos 20 tem o efeito de evocar a primeira visita ao "speakeasy" (bar secreto escondido no subsolo); a primeira experiência sexual - que a privacidade e intimidade do automóvel proporcionavam -; a procura de uma felicidade concreta e imediata, etc. Contudo, a revolta dos jovens constituiu simplesmente o corolário de um desdém pelas condições económico - sociais vigentes, e não se confinou aos Estados Unidos da América, mas atingiu todo o mundo ocidental, em resultado da primeira grande guerra do século. Dado o "boom" na indústria americana, com as suas fábricas gigantescas e ruidosas e a resultante agressividade em larga escala, o culto da elegância nos modos e no porte (que a época anterior favorecera) foi progressivamente abandonado: com guerra ou sem guerra, cada vez se tornava mais difícil para os jovens adoptarem padrões de comportamento que não se ajustassem ao mundo de negócios em que teriam de competir

    Predominant factors of institutionalization in the elderly: a comparative study between home nursing and community dwelling

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    Purpose: The purpose of this paper was to detect the most significant factors associated with each living alternative to improve socialization and mental health of the elderly. The measurements included affective evaluation, cognitive assessment, anxiety level, physical functionality, quality of life and social relationships. Individuals in home nursing residences were older and had worse affective status, functionality, cognitive state and quality of life. Social relationships in community people were better than in the institutionalized condition, particularly for less aged people. Design/methodology/approach: Comparative descriptive study realized in 200 people older than 70 years in home nursing placement versus community dwelling conditions. Findings: Multivariate analysis and logistic regression indicated that greater disability and poorer quality of social relationships were the main factors influencing the institutionalization process. Specifically, the Sociotype Questionnaire appeared as an efficient tool concerning the detection of social isolation effects as well as an acceptable integrator of prosocial information about home nursing placement. Originality/value: The Geriatric Sociotype survey has shown usefulness in the evaluation of the social network of elderly people, both from the point of view of assessment and prognosis. In this sense it is considered that one of the main contributions of this study is to have included the qualitative evaluation of social relations, and to observe the differences according to the place of residence

    Nonsingular and accelerated expanding universe from effective Yang-Mills theory

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    The energy-momentum tensor coming from one-parameter effective Yang- Mills theory is here used to describe the matter-energy content of the homogeneous and isotropic Friedmann cosmology in its early stages. The behavior of all solutions is examined. Particularly, it is shown that only solutions corresponding to an open model allow the universe to evolve into an accelerated expansion. This result appears as a possible mechanism for an inflationary phase produced by a vector field. Further, depending on the value of some parameters characterizing the system, the resulting models are classified as singular or nonsingular.Comment: 15 pages, 7 figures, some discussions were simplified and new remarks were introduce

    Frustration - how it can be measured

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    A misfit parameter is used to characterize the degree of frustration of ordered and disordered systems. It measures the increase of the ground-state energy due to frustration in comparison with that of a relevant reference state. The misfit parameter is calculated for various spin-glass models. It allows one to compare these models with each other. The extension of this concept to other combinatorial optimization problems with frustration, e.g. p-state Potts glasses, graph-partitioning problems and coloring problems is given.Comment: 10 pages, 1 table, no figures, uses revtex.st

    Dynamical decoupling of unbounded Hamiltonians

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    We investigate the possibility to suppress interactions between a finite dimensional system and an infinite dimensional environment through a fast sequence of unitary kicks on the finite dimensional system. This method, called dynamical decoupling, is known to work for bounded interactions, but physical environments such as bosonic heat baths are usually modelled with unbounded interactions, whence here we initiate a systematic study of dynamical decoupling for unbounded operators. We develop a sufficient decoupling criterion for arbitrary Hamiltonians and a necessary decoupling criterion for semibounded Hamiltonians. We give examples for unbounded Hamiltonians where decoupling works and the limiting evolution as well as the convergence speed can be explicitly computed. We show that decoupling does not always work for unbounded interactions and provide both physically and mathematically motivated examples.Comment: 18 pages, 3 figure

    Sphingosine 1-phosphate modulates antigen capture by murine langerhans cells via the S1P2 receptor subtype

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    Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs. Recently, it has been indicated that a topical application of the sphingolipid sphingosine 1-phosphate (S1P) prevents the inflammatory response in CHS, but the molecular mechanism is not fully elucidated. Here we indicate that treatment of mice with S1P is connected with an impaired antigen uptake by Langerhans cells (LCs), the initial step of CHS. Most of the known actions of S1P are mediated by a family of five specific G protein-coupled receptors. Our results indicate that S1P inhibits macropinocytosis of the murine LC line XS52 via S1P2 receptor stimulation followed by a reduced phosphatidylinositol 3-kinase (PI3K) activity. As down-regulation of S1P2 not only diminished S1P-mediated action but also enhanced the basal activity of LCs on antigen capture, an autocrine action of S1P has been assumed. Actually, S1P is continuously produced by LCs and secreted via the ATP binding cassette transporter ABCC1 to the extracellular environment. Consequently, inhibition of ABCC1, which decreased extracellular S1P levels, markedly increased the antigen uptake by LCs. Moreover, stimulation of sphingosine kinase activity, the crucial enzyme for S1P formation, is connected not only with enhanced S1P levels but also with diminished antigen capture. These results indicate that S1P is essential in LC homeostasis and influences skin immunity. This is of importance as previous reports suggested an alteration of S1P levels in atopic skin lesions

    Characterization of the Conus bullatus genome and its venom-duct transcriptome

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    <p>Abstract</p> <p>Background</p> <p>The venomous marine gastropods, cone snails (genus <it>Conus</it>), inject prey with a lethal cocktail of conopeptides, small cysteine-rich peptides, each with a high affinity for its molecular target, generally an ion channel, receptor or transporter. Over the last decade, conopeptides have proven indispensable reagents for the study of vertebrate neurotransmission. <it>Conus bullatus </it>belongs to a clade of <it>Conus </it>species called <it>Textilia</it>, whose pharmacology is still poorly characterized. Thus the genomics analyses presented here provide the first step toward a better understanding the enigmatic <it>Textilia </it>clade.</p> <p>Results</p> <p>We have carried out a sequencing survey of the <it>Conus bullatus </it>genome and venom-duct transcriptome. We find that conopeptides are highly expressed within the venom-duct, and describe an <it>in silico </it>pipeline for their discovery and characterization using RNA-seq data. We have also carried out low-coverage shotgun sequencing of the genome, and have used these data to determine its size, genome-wide base composition, simple repeat, and mobile element densities.</p> <p>Conclusions</p> <p>Our results provide the first global view of venom-duct transcription in any cone snail. A notable feature of <it>Conus bullatus </it>venoms is the breadth of A-superfamily peptides expressed in the venom duct, which are unprecedented in their structural diversity. We also find SNP rates within conopeptides are higher compared to the remainder of <it>C. bullatus </it>transcriptome, consistent with the hypothesis that conopeptides are under diversifying selection.</p
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