236 research outputs found

    A Study on Awareness Levels and Adaptation Strategies for Climate Variability among Farmers

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    Climate change has become a severe threat to the development and communities around the globe are already experiencing the sudden impacts. It is also being assumed that climate change will have significant negative impacts on agricultural productivity .In this respect 120 farmers were interviewed as respondents to explore the climate variability/change awareness and farmers mitigation strategies. This study was conducted in Rangareddy district of Telangana .Three mandals were selected randomly .From each mandal two villages and from each village 20 farmers were selected randomly .Total number of respondents are 120 Findings of the study indicated that farmers\u27 awareness regarding climate variability was very poor they were just having knowledge on behalf of their farming experience. Varied response was seen regarding causes of climate change. In addition, adaptations of mitigation strategies such as natural resource management, water harvesting, crop diversification migration to less weather prone area and USAge of weather resistant varieties were almost negligible. Results showed that out of 15 adaptation strategies, micro irrigation ranked first among farm adaptive measures, while crop insurance has ranked as least utilized. Conservation agriculture could be the most viable strategy. Farmers have to utilize their existing resources in judicious ways. It is suggested on the basis of findings that role of extension field staff should be diversified. Farmers need capacity building regarding conservation agriculture. Moreover, it is dire need to popularize climate change and its adaptation through effective media campaign

    Degradation of crude oil using the indigenous isolate Bacillus sp SEA18

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    Hydrocarbon contamination in the environment today is gaining more importance as they are carcinogenic and neurotoxic. Methods to degrade these hydrocarbons are rightfully demanding and researchers are on a lookout for new and indigenous species as they are sustained in that niche by utilizing the resources available. Because of the capabilities exhibited by bacteria in environmental remediation, this study, focuses on isolating an indigenous bacterium from oil-contaminated site and evaluate its potential in degrading oils. The isolate obtained was identified as Bacillus sp and was found to show the degradation of crude oil to an extent of 80% after 60 days of incubation. The analysis was confirmed by GC-MS analysis that showed a significant reduction in the number of hydrocarbons. This capability of this bacterium to produce biosurfactants promises this species to play a role in degradation as biosurfactants would enhance the degradation process. This study, therefore, reinforces the fact that indigenous species are potential hydrocarbon degraders due to their adaptability and endurance

    Degradation of crude oil using the indigenous isolate Bacillus sp SEA18

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    317-326Hydrocarbon contamination in the environment today is gaining more importance as they are carcinogenic and neurotoxic. Methods to degrade these hydrocarbons are rightfully demanding and researchers are on a lookout for new and indigenous species as they are sustained in that niche by utilizing the resources available. Because of the capabilities exhibited by bacteria in environmental remediation, this study, focuses on isolating an indigenous bacterium from oil-contaminated site and evaluate its potential in degrading oils. The isolate obtained was identified as Bacillus sp and was found to show the degradation of crude oil to an extent of 80% after 60 days of incubation. The analysis was confirmed by GC-MS analysis that showed a significant reduction in the number of hydrocarbons. This capability of this bacterium to produce biosurfactants promises this species to play a role in degradation as biosurfactants would enhance the degradation process. This study, therefore, reinforces the fact that indigenous species are potential hydrocarbon degraders due to their adaptability and endurance

    Efficacy of lysine versus mupirocin in the treatment of non-diabetic foot ulcer: the sessing scale for assessment of pressure ulcer

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    Background: This present studies intended to evaluate the wound healing ability, efficacy and tolerability of lysine cream (15%) in non- diabetic foot ulcer assessed by way of sessing scale.Methods: A randomized, open-label, interventional study was directed on 20 subjects (participants) non-diabetic ulcers. Participants were grouped into two groups, control (n=10) and case (n=10). The control was treated with standard treatment with mupirocin and the test group was treated with standard treatment alongside lysine cream (15%) twice every day. Wound healing in the participants was assessed by the sessing scales.Results: A total of 20 participants were allotted into two groups. The results expressed as mean±standard deviation values imply the size and depth of the foot ulcer from the first week to the 8th week. Both the groups showed a significant increase the ulcer healing and decrease the pressure of foot ulcer of over a period of 8 weeks. Assessment of the first week showed no significant ulcer healing and its pressure. The overall outcome indicated that the lysine-treated group extensively reduced each of the parameters favouring wound healing than the standard therapy with mupirocin (control group).Conclusions: Results concluded that, lysine cream is better efficacious in the repair of wound and additionally well tolerated compared to mupirocin

    Neuropathology of HIV/AIDS with an overview of the Indian scene

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    Neurological manifestations of HIV infection and AIDS are being recognized with a frequency that parallels the increasing number of AIDS cases. Next to sub-Saharan Africa, India has the second largest burden of HIV related pathology, essentially caused by HIV-1 clade C in both the geographic locales, in contrast to USA and Europe. But the true prevalence of HIV related neuroinfections and pathology is not available due to inadequate medical facilities, social stigma and ignorance that lead to underdiagnosis. Neurotuberculosis, followed by cryptococcosis and toxoplasmosis in various combinations are the major neuropathologies reflecting the endemicity and manifesting clinically by reactivation of latent infection. Discordance in the clinical prevalence of various infections, when compared to pathological studies highlight similarities in clinical, radiological modalities of diagnosis and inherent problems in establishing definitive diagnosis. Viral infections appear to be relatively rare. Inspite of heavy burden of HIV/AIDS, HIV associated neoplasia is infrequent, including primary CNS lymphomas. HIV encephalitis and HIV associated dementia are considered infrequent, though systematic studies have just been initiated in various centres. Peripheral neuropathy characteristically manifests with vasculitic neuropathy while diffuse infiltrative lymphocytosis syndrome (DILS) involving nerves has not been reported from India. Spinal cord pathology including vacuolar myelopathy is rare, even in asymptomatic cases. Till now the AIDS cases in India were drug naĂŹve but a new cohort of cases following initiation of HAART therapy as a national policy is soon emerging, altering the biology and evolution of HIV/AIDS in India. Lacunae in the epidemiology, diagnosis and study of biology of HIV/AIDS are outlined for future research

    A novel approach to improve GNSS Precise Point Positioning during strong ionospheric scintillation: theory and demonstration

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    At equatorial latitudes, ionospheric scintillation is the major limitation in achieving high-accuracy GNSS positioning. This is because scintillation affects the tracking ability of GNSS receivers causing losses of lock and degradation on code pseudorange and carrier phase measurements, thus degrading accuracy. During strong ionospheric scintillation, such effects are more severe and GNSS users cannot rely on the integrity, reliability, and availability required for safety-critical applications. In this paper, we propose a novel approach able to greatly reduce these effects of scintillation on precise point positioning (PPP). Our new approach consists of three steps: 1) a new functional model that corrects the effects of range errors in the observables; 2) a new stochastic model that uses these corrections to generate more accurate positioning; and 3) a new strategy to attenuate the effects of losses of lock and consequent ambiguities re-initializations that are caused by the need to re-initialize the tracking. We demonstrate the effectiveness of our method in an experiment using a 30-day static dataset affected by different levels of scintillation in the Brazilian southeastern region. Even with limitations imposed by data gaps, our results demonstrate improvements of up to 80% in the positioning accuracy. We show that, in the best cases, our method can completely negate the effects of ionospheric scintillation and can recover the original PPP accuracy that would have existed without any scintillation. The significance of this paper lies in the improvement it offers in the integrity, reliability, and availability of GNSS services and applications.</p

    Increasing outdoor host-seeking in Anopheles gambiae over 6 years of vector control on Bioko Island.

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    BACKGROUND: Vector control through indoor residual spraying (IRS) has been employed on Bioko Island, Equatorial Guinea, under the Bioko Island Malaria Control Project (BIMCP) since 2004. This study analyses the change in mosquito abundance, species composition and outdoor host-seeking proportions from 2009 to 2014, after 11 years of vector control on Bioko Island. METHODS: All-night indoor and outdoor human landing catches were performed monthly in the Bioko Island villages of Mongola, Arena Blanca, Biabia and Balboa from 2009 to 2014. Collected mosquitoes were morphologically identified and a subset of Anopheles gambiae sensu lato (s.l.) were later identified molecularly to their sibling species. Mosquito collection rates, species composition and indoor/outdoor host-seeking sites were analysed using generalized linear mixed models to assess changes in mosquito abundance and behaviour. RESULTS: The overall mosquito collection rate declined in each of the four Bioko Island villages. Anopheles coluzzii and Anopheles melas comprised the An. gambiae s.l. mosquito vector population, with a range of species proportions across the four villages. The proportion of outdoor host-seeking An. gambiae s.l. mosquitoes increased significantly in all four villages with an average increase of 58.8 % [57.9, 59.64 %] in 2009 to 70.0 % [67.8, 72.0 %] in 2014. Outdoor host-seeking rates did not increase in the month after an IRS spray round compared to the month before, suggesting that insecticide repellency has little impact on host-seeking behaviour. CONCLUSION: While vector control on Bioko Island has succeeded in substantial reduction in overall vector biting rates, populations of An. coluzzii and An. melas persist. Host-seeking behaviour has changed in these An. gambiae s.l. populations, with a shift towards outdoor host-seeking. During this study period, the proportion of host-seeking An. gambiae s.l. caught outdoors observed on Bioko Island increased to high levels, exceeding 80 % in some locations. It is possible that there may be a genetic basis underlying this large shift in host-seeking behaviour, in which case outdoor feeding could pose a serious threat to current vector control programmes. Currently, the BIMCP is preparing for this potential challenge by testing source reduction as a complementary control effort that also targets outdoor transmission

    TLR 9 Activation in Dendritic Cells Enhances Salmonella Killing and Antigen Presentation via Involvement of the Reactive Oxygen Species

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    Synthetic CpG containing oligodeoxynucleotide Toll like receptor-9 agonist (CpG DNA) activates innate immunity and can stimulate antigen presentation against numerous intracellular pathogens. It was observed that Salmonella Typhimurium growth can be inhibited by the CpG DNA treatment in the murine dendritic cells. This inhibitory effect was mediated by an increased reactive oxygen species production. In addition, it was noted that CpG DNA treatment of dendritic cells during Salmonella infection leads to an increased antigen presentation. Further this increased antigen presentation was dependent on the enhanced reactive oxygen species production elicited by Toll like receptor-9 activation. With the help of an exogenous antigen it was shown that Salmonella antigen could also be cross-presented in a better way by CpG induction. These data collectively indicate that CpG DNA enhance the ability of murine dendritic cells to contain the growth of virulent Salmonella through reactive oxygen species dependent killing
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