660 research outputs found
Cost drivers of integrated maintenance in high-value systems
High value systems are determined by a wide structure, where operations are considered to be one structural component. Nowadays “down-time” as a major impact in the operation costs of any system. To avoid or minimize “down-time” it is essential to match the appropriate maintenance to each failure. Therefore, it is relevant to determine the cost drivers of integrated maintenance in any system, in order to minimize the overall cost. It is common to use Value Driven Maintenance (VDM) to capture the cost drivers in maintenance. VDM is a methodology which relies in four distinct areas: Asset Utilization; Resource Allocation; Control Cost and Health and Safety and Environment. Within each category it is possible to allocate different cost drivers, building a framework for each system studied. The aim of this paper is to categorize the cost drivers of rail infrastructure networks, associating them with the maintenance preformed for each case. Furthermore, analysis of which part of the track falls under each VDM category as well as the general failure causes and effects will be included in the framework presented. Finally relating the maintenance type for each effect will provide the necessary inputs towards a cost model structure. The benefit of achieving a successful model will be the optimization of the cost in integrated maintenance of the rail infrastructure
The case for new academic workspaces
Executive summary: This report draws upon the combined efforts of
a number of estates professionals, architects,
academics, designers, and senior managers
involved in the planning of new university buildings
for the 21st century. Across these perspectives,
all would agree – although perhaps for different
reasons - that this planning is difficult and that a
number of particular considerations apply in the
design of academic workspaces. Despite these
difficulties, they will also agree that when this
planning goes well, ‘good’ buildings are truly
transformational – for both the university as a
whole and the people who work and study in them.
The value of well-designed buildings goes far
beyond their material costs, and endures long after
those costs have been forgotten ..
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Integrated processes in person perception: matching novel faces and voices [oral presentation]
A series of studies investigated whether people can match novel faces and voices of the same age (20-30) and sex at a level significantly above chance. The studies also tested whether accuracy is affected by facial stimuli type: static or moving, and the order of stimuli presentation: face first or voice first. In Experiment 1 participants saw a face and heard a voice one after the other. They had to decide whether the stimuli were matching or not matching. When the correct matching stimulus was present participants consistently performed above chance level, regardless of facial stimuli type or stimuli order. When the correct matching stimulus was not present participants were either just guessing (voice first) or significantly below chance (face first). In Experiment 2 and 3 participants had to select the correct matching stimuli in a two-alternative forced choice task. The correct matching stimuli was always present in Experiment 2. It was never present in Experiment 3. Experiments 2 and 3 replicated the results of Experiment 1. Participants in Experiment 2 were more accurate when the correct matching stimulus was present in position 1. Experiment 3 showed that a response bias was operating; participants selected stimulus 1 more often than stimulus 2. However, the bias did not wholly explain the overall above-chance accuracy levels in Experiment 2. This set of results show that people can accurately match novel faces and voices, indicating that faces and voices offer concordant information. Face and voice perception appears to be an integrated process
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Earwitness memory: factors that influence voice recognition accuracy across the lifespan [poster presentation]
We aimed to explore the effect of change in frequency (F0 in Hz) and speech rate (syllables per second - SPS) on voice recognition accuracy. In part one of our experiment, participants (M=36; F=36; aged 18-30 years) were given a 2AFC voice matching task which involved hearing (binaural headphone presentation) synthesised (using NaturalReader 12) voices (uttering the phrase “spring is the season where flowers appear, summer is the warmest season of the year”). Participants had to identify whether the two voices were the ‘same’ or ‘different’ (using a key press, left/right). There were six target voices (six different identities, three male and three female) in total. In each trial the to be matched voices comprised the original voice or a modulated version (increased/decreased F0 or increased/decreased SPS) of the original voice presented in a random order. In part two of our experiment, the same participants heard the original voice and the modulated versions in a random order. After presenting each voice, participants had to decide whether the voice they heard was ‘male’ or ‘female’ (using a key press, left/right). Results from part one indicated that participants could discriminate a more subtle pitch shift than they could for speech rate. Results from part two indicated that participants correctly identified the sex of the speaker when SPS was modulated for both male and female voices, and when F0 was modulated for male voices. However, participants incorrectly identified a female voice as ‘male’ when F0 decreased. This suggests that both pitch and speech rate variations are important for accurate speaker identification and voice discrimination
An exploration of the accentuation effect: errors in memory for voice fundamental frequency (F0) and speech rate
The accentuation effect demonstrates how memory often reflects category typical representations rather than the specific features of learned items. The present study investigated the impact of manipulating fundamental frequency (F0) and speech rate (syllables per second) on immediate target matching performance (selecting a voice from a pair to match a previously heard target voice) for a range of synthesised voices. It was predicted that when participants were presented with high or low frequency target voices, voices even higher or lower in frequency would be selected. The same pattern was also predicted for speech rate. Inconsistent with the accentuation account, the results showed a general bias to select voices higher in frequency for high, moderate, and low frequency target voices. For speech rate, listeners selected voices faster in rate for slow rate target voices. Overall it seems doubtful that listeners rely solely on categorical information about voices during recognition
Challenges in cost analysis of innovative maintenance of distributed high-value assets
Condition monitoring is an increasingly important activity, but there is often little thought given to how a condition monitoring approach is going to impact the cost of operating a system. This paper seeks to detail the challenges facing such an analysis and outline the likely steps such an analysis will have to take to more completely understand the problem and provide suitable cost analysis. Adding sensors might be a relatively simple task, but those sensors come with associated cost; not only of the sensor, but of the utilities required to power them, the data gathering and processing and the eventual storage of that data for regulatory or other reasons. By adding condition monitoring sensors as a sub- system to the general system an organisation is required to perform maintenance to the new sensors sub-system. Despite these difficulties it is anticipated that for many high value assets applying condition monitoring will enable significant cost savings through elimination of maintenance activities on assets that do not need such cost and effort expended on them. Further savings should be possible through optimisation of maintenance schedules to have essential work completed at more cost efficient times
Methodological queries regarding "Exploratory quantum resonance spectrometry" (Zhang et al., 2014) [letter to the editor]
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice
5,6-dimethylxanthenone-4-acetic acid, a novel antivascular anticancer drug, has completed Phase I clinical trial. Its actions in mice include tumour necrosis factor induction, serotonin release, tumour blood flow inhibition, and the induction of tumour haemorrhagic necrosis and regression. We have used mice with a targeted disruption of the tumour necrosis factor receptor-1 gene as recipients for the colon 38 carcinoma to determine the role of tumour necrosis factor signalling in the action of 5,6-dimethylxanthenone-4-acetic acid. The pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid, as well as the degree of induced plasma and tissue tumour necrosis factor, were similar in tumour necrosis factor receptor-1−/− and wild-type mice. However, the maximum tolerated dose of 5,6-dimethylxanthenone-4-acetic acid was considerably higher in tumour necrosis factor receptor-1−/− mice (>100 mg kg−1) than in wild-type mice (27.5 mg kg−1). The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (25 mg kg−1) was strongly attenuated in tumour necrosis factor receptor-1−/− mice. However, the reduced toxicity in tumour necrosis factor receptor-1−/− mice allowed the demonstration that at a higher dose (50 mg kg−1), 5,6-dimethylxanthenone-4-acetic acid was curative and comparable in effect to that of a lower dose (25 mg kg−1) in wild-type mice. The 5,6-dimethylxanthenone-4-acetic acid -induced rise in plasma 5-hydroxyindoleacetic acid, used to reflect serotonin production in a vascular response, was larger in colon 38 tumour bearing than in non-tumour bearing tumour necrosis factor receptor-1−/− mice, but in each case the response was smaller than the corresponding response in wild-type mice. The results suggest an important role for tumour necrosis factor in mediating both the host toxicity and antitumour activity of 5,6-dimethylxanthenone-4-acetic acid, but also suggest that tumour necrosis factor can be replaced by other vasoactive factors in its antitumour action, an observation of relevance to current clinical studies
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A new measure of workplace innovation
Despite the popularity of Workplace Innovation (WI) and its demonstrable utility for supporting both organisational productivity and employee well-being, there is at present no reliable and valid measure of WI practices for use in research and workplace settings. The aim of this paper is to present the development of a measure of WI climate. The study involved 855 individuals across all levels of three organisations, and a survey of WI practices that was based on four underlying elements: jobs and teams; organisational structures, management and procedures; employee-driven improvement and innovation; and co-created leadership and employee voice. The original list of items was developed in consultation with employers and practitioners. WI was assessed as climate perceptions. A series of analyses were undertaken on the measure, demonstrating good psychometric properties, including consistency of the factor structure, internal reliability, construct validity, and criterion validity. Support for reliability and validity of the new 19-item measure with four elements is presented. Employees who experienced the four elements of WI climate more positively also enjoyed greater work engagement and job satisfaction, outlining criterion validity of the new measure. The availability of a rigorous and reliable measure of WI climate offers a tool for practitioners and researchers tasked with communicating and promoting WI in diverse workplace settings and with diverse groups of stakeholders. We hope that this new measure of WI will stimulate further research on the role of WI in promoting healthy and productive workplaces
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