Neural Entrainment is Associated with Subjective Groove and Complexity for Performed but not Mechanical Musical Rhythms

Both movement and neural activity in humans can be entrained by the regularities of an external stimulus, such as the beat of musical rhythms. Neural entrainment to auditory rhythms supports temporal perception, and is enhanced by selective attention and by hierarchical temporal structure imposed on rhythms. However, it is not known how neural entrainment to rhythms is related to the subjective experience of groove (the desire to move along with music or rhythm), the perception of a regular beat, the perception of complexity, and the experience of pleasure. In two experiments, we used musical rhythms (from Steve Reich’s Clapping Music) to investigate whether rhythms that are performed by humans (with naturally variable timing) and rhythms that are mechanical (with precise timing), elicit differences in 1) neural entrainment, as measured by inter-trial phase coherence, and 2) subjective ratings of the complexity, preference, groove, and beat strength of rhythms. We also combined results from the two experiments to investigate relationships between neural entrainment and subjective perception of musical rhythms. We found that mechanical rhythms elicited a greater degree of neural entrainment than performed rhythms, likely due to the greater temporal precision in the stimulus, and the two types only elicited different ratings for some individual rhythms. Neural entrainment to performed rhythms, but not to mechanical ones, correlated with subjective desire to move and subjective complexity. These data therefore suggest multiple interacting influences on neural entrainment to rhythms, from low-level stimulus properties to high-level cognition and perception

Enheduanna – A Manifesto of Falling: first demonstration of a live brain-computer cinema performance with multi-brain BCI interaction for one performer and two audience members

The new commercial-grade Electroencephalography (EEG)-based Brain-Computer Interfaces (BCIs) have led to a phenomenal development of applications across health, entertainment and the arts, while an increasing interest in multi-brain interaction has emerged. In the arts, there is already a number of works that involve the interaction of more than one participants with the use of EEG-based BCIs. However, the field of live brain-computer cinema and mixed-media performances is rather new, compared to installations and music performances that involve multi-brain BCIs. In this context, we present the particular challenges involved. We discuss Enheduanna – A Manifesto of Falling, the first demonstration of a live brain-computer cinema performance that enables the real-time brain-activity interaction of one performer and two audience members; and we take a cognitive perspective on the implementation of a new passive multi-brain EEG-based BCI system to realise our creative concept. This article also presents the preliminary results and future work

In need of mediation: The relation between syntax and information structure

This paper defends the view that syntax does not directly interact with information structure. Rather, information structure affects prosody, and only the latter has an interface with syntax. We illustrate this point by discussing scrambling, focus preposing, and topicalization. The position entertained here implies that syntax is not very informative when one wants to narrow down the interpretation of terms such as “focus”, “topic”, etc

The German Music@Home: Validation of a questionnaire measuring at home musical exposure and interaction of young children.

The present study introduces the German version of the original version of the Music@Home questionnaire developed in the UK, which systematically evaluates musical engagement in the home environment of young children. Two versions are available, an Infant version for children aged three to 23 months and a Preschool version for children aged two to five and a half years. For the present study, the original Music@Home questionnaire was translated from English into German and 656 caregivers completed the questionnaire online. A confirmatory factor analysis showed moderate to high fit indices for both versions, confirming the factor structure of the original questionnaire. Also, the reliability coefficients for the subscales (Parental beliefs, Child engagement with music, Parent initiation of singing, Parent initiation of music-making for the Infant version and Parental beliefs, Child engagement with music, Parent initiation of music behavior and Breadth of musical exposure for the Preschool version) ranged from moderate to high fits. Furthermore, the test-retest analysis (N = 392) revealed high correlations for the general factor and all subscales confirming their internal reliability. Additionally, we included language questionnaires for children of two and three years of age. Results showed that higher scores on the Music@Home questionnaire were moderately associated with better language skills in two-year-olds (N = 118). In sum, the study presents the validated German Music@Home questionnaire, which shows good psychometric properties. The two versions of the questionnaire are available for use in order to assess home musical engagement of young children, which could be of interest in many areas of developmental research

Principles of optimally placing data in tertiary storage libraries

Recently, technological advances have resulted in the wide availability of commercial products offering near-line, robot-based, tertiary storage libraries. Thus, such libraries have become a crucial component of modern largescale storage servers, given the very large storage requirements of modern applications. Although the subject of optimal data placement (ODP) strategies has received considerable attention for other storage devices (such as magnetic and optical disks and disk arrays), the issue of optimal data placement in tertiary libraries has been neglected. The latter issue is more critical since tertiary storage remains three orders of magnitude slower than secondary storage. In this paper, we address this issue by deriving such optimal placement algorithms. First, we study the ODP problem in disk libraries (jukeboxes) and subsequently, in tape libraries. In our studies, we consider different scheduling algorithms, different configurations of disk libraries and different tape l..

lmmunohistochemical expression of the p53, mdm2, p21/Waf-1, Rb, p16, Ki67, Cyclin DI, Cyclin A and Cyclin B1 proteins and apoptotic index in T-cell lymphomas

Fifty-seven cases of T-cell lymphomas (TCL) including 5 lymphoblastic (T-LBL) and 52 peripheral TCL (PTCL) were analyzed by immunohistochemistry for the expression of p53, mdm2, p21, Rb, cyclin DI, cyclin A, cyclin B1, and Ki67IMIB1 proteins and 39/52 PTCL were also analyzed for the expression of p16 protein and for the presence of apoptotic cells by the TUNEL method. The aim was to search for abnormal immunoprofiles of p53 and Rb growth control pathways and to determine the proliferative activity and the apoptotic index of TCL. Abnormal overexpression of p53, p21 and mdm2, in comparison to normal lymph nodes, was found in 12/57,10/57 and 2/57 cases of TCL, respectively. Abnormal loss of Rb and p16 expression was found in 1/57 and 2/39 cases, respectively, whereas abnormal overexpression of cyclin D1 was not detected in any of the 57 cases. Our data revealed entity-related p53/p21/mdm2 phenotypes. Indeed, most nodal and cutaneous CD30+ anaplastic large cell lymphomas (ALCL) showed concomitant overexpression of p53 and p21 proteins (718 cases), and mdm2 was overexpressed in 2 p53-positive nodal ALCL. In contrast, overexpression of p53 was found in 3/17 cases of nodal peripheral TCL unspecified (PTCL-UC) and 217 non- ALCL cutaneous pleomorphic TCL. Overexpression of p21 protein was detected in 213 p53-positive PTCLUC and in 112 p53-positive non-ALCL cutaneous pleomorphic TCL. Finally, al1 the remaining 25 cases of TCL did not show p53 and p21 overexpression. Overali, the p53+/p21+ phenotype in 10157 TCL suggests wildtype p53 capable of inducing p21 expression. The highest apoptotic index (Al) was found in ALCL and a positive correlation between apoptotic index and Ki67 index (p<0.001) was detected. Ki67, cyclin A and cyclin B1 expression was found in al1 57 TCL and on the basis of the combined use of these 3 variables, 3 groups of proliferative activity,.could be determined: a) high in ALCL and T-LBL, b) low in mycosis fungoides (MF) and γδ hepatosplenic TCL, and c) intermediate in the remaining TCL entities. The proliferative activity in the 12 p53 overexpressing cases was higher in comparison to the 45 p53-negative cases. Ki67 expresion in more than 25% of tumour cells showed significant correlation with p53 overexpression (p<0.001). Rb expression tended to be parallel to Ki67, cyclin A and cyclin B1 expression in al1 but one case of nodal PTCL-UC which displayed loss of RB expression. Interestingly, this case was p53-negative, whereas the p53-positive cases were Rb-positive. These findings suggest that different pathogenetic routes may function in some TCL, involving either the p53 or, less frequently, the Rb pathways