Silvery Waves

Ocean waves with ship, moon, and clouds in background; Two seahorses outside of framehttps://scholarsjunction.msstate.edu/cht-sheet-music/11315/thumbnail.jp

PHOTOGRAPHING COYOTES

Wildlife photography has become an increasingly popular hobby over the last 10 years. Coyotes (Canis latrans) are among the more difficult animals to photograph under natural field conditions (i.e., in the wild ). For studying and photographing coyotes behaving routinely, I recommend the use of a draw station (i.e., cow carcass) and a blind that will all low relatively close inspection of coyote interactions

THE COYOTE IN SOUTHWESTERN FOLKLORE

Perhaps one of the first mentions of the coyote (Canis latrans) by Anglos in early-day journalism was from Mask Twain\u27s notes during his travels through the plains frontier in the early- to mid-19th century. Touring the frontier region before its inevitable subjugation to ranching and farming, Twain wrote of the coyote and its larger more infamous cousin, the wolf(C. lupus), In words which left no doubt to the reader the popular sentiments for such predators of the day Although derogatory in some respects, Twain did concede respect for Canis latrans and made mention of the tricks the coyote would play on domestic dogs as the wagons lumbered across the pristine landscape

The Alps : Marche Di Bravoura

https://digitalcommons.library.umaine.edu/mmb-ps/1765/thumbnail.jp

Woodland Echoes

https://digitalcommons.library.umaine.edu/mmb-ps/1723/thumbnail.jp

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells

Type 2 hereditary hemochromatosis (HH) or juvenile hemochromatosis is an early onset, genetically heterogeneous, autosomal recessive disorder of iron overload. Type 2A HH is caused by mutations in the recently cloned hemojuvelin gene (HJV; also called HFE2) (Papanikolaou, G., Samuels, M. E., Ludwig, E. H., MacDonald, M. L., Franchini, P. L., Dube, M. P., Andres, L., MacFarlane, J., Sakellaropoulos, N., Politou, M., Nemeth, E., Thompson, J., Risler, J. K., Zaborowska, C., Babakaiff, R., Radomski, C. C., Pape, T. D., Davidas, O., Christakis, J., Brissot, P., Lockitch, G., Ganz, T., Hayden, M. R., and Goldberg, Y. P. (2004) Nat. Genet. 36, 77–82), whereas Type 2B HH is caused by mutations in hepcidin. HJV is highly expressed in both skeletal muscle and liver. Mutations in HJV are implicated in the majority of diagnosed juvenile hemochromatosis patients. In this study, we stably transfected HJV cDNA into human embryonic kidney 293 cells and characterized the processing of HJV and its effect on iron homeostasis. Our results indicate that HJV is a glycosylphosphatidylinositol-linked protein and undergoes a partial autocatalytic cleavage during its intracellular processing. HJV co-immunoprecipitated with neogenin, a receptor involved in a variety of cellular signaling processes. It did not interact with the closely related receptor DCC (deleted in Colon Cancer). In addition, the HJV G320V mutant implicated in Type 2A HH did not co-immunoprecipitate with neogenin. Immunoblot analysis of ferritin levels and transferrin-55Fe accumulation studies indicated that the HJV-induced increase in intracellular iron levels in human embryonic kidney 293 cells is dependent on the presence of neogenin in the cells, thus linking these two proteins to intracellular iron homeostasis

Woodland Echoes / words by Addison P. Wyman

Cover: a drawing of a river flowing in the wood; Publisher: McKinley Music Co. (Chicago)https://egrove.olemiss.edu/sharris_b/1092/thumbnail.jp

Driven From Home

https://digitalcommons.library.umaine.edu/mmb-ps/1981/thumbnail.jp