Oxidation of the secondary alcohol present in some common sugar derivatives with Dess-Martin periodinane

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Influence of different storage temperatures and packing material in extending shelf life and quality attributes of palmyrah (Borassus flabellifer L.) neera

Palmyrah neera (inflorescence sap) is susceptible to natural fermentation at ambient temperature within a few hours of extraction due to enzymatic and microbial activity. Once fermented, neera becomes toddy which is unsuitable as a health drink or as a value-added product. Therefore, a study was carried out to investigate the influence of different packing materials and storage conditions on the shelf life and to keep the quality of palmyrah neera. The experiment was conducted in a completely randomised factorial design with two factors at unequal levels replicated thrice. HDPE 50 micron pouch (P1), PET bottle (P2) and glass bottle (P3) and cold storage at 2 oC (S1), cold storage at 4 oC (S2) and refrigerated storage (8-10 oC) (S3) were the packing material and storage conditions respectively used during experimentation. Physio-chemical properties viz., total soluble solids, pH and reducing sugars showed an increasing trend up to the 4th week of storage. At the same time, phenols, titrable acidity and alcohol content increased up to the 6th week of storage. Maximum total soluble solids (10.80 oBrix), reducing sugars (5.76%), minimum phenolic content (0.323 mg) and titrable acidity (1.116%) were recorded when palmyrah neera was packed in HDPE 50 micron pouch, whereas the maximum total soluble solids (10.83oBrix), reducing sugars (5.75%), minimum phenolic content (0.322 mg) and titrable acidity (1.14%) were recorded when palmyrah neera was stored at 2 oC. Among the different packing material and storage conditions, HDPE 50 micron and storage at 2 oC was effective in extending the shelf life and quality attributes of palmyrah neera

Experimental Evaluation of Strength Degradation Temperature for Carbon Epoxy Filament Wound Composite

Polymeric composites have been widely used in various structural and thermal aerospace applications. Polymeric composites having high strength and high modulus reinforcement are ideally suited for lot of critical aerospace applications as structure is designed with high specific strength and high specific modulus. In case of launch vehicles/ missile one such application is design and manufacturing of solid rocket motor casing with polymeric composites as it give high performance and reduces inert weight of propulsion system. The high specific strength and high specific modulus of composite materials makes it ideal choice for designing the composite rocket motor case (CRMC). These are manufactured with filament winding process. As per ASTM D 2290 test method, the apparent tensile strength can be evaluated by preparing ring specimens from filament wound shell which simulates the hoop winding and cylindrical geometry of composite motor case. During flight in trajectory, the temperature on external surface of rocket motor will rise due to kinetic heating as result of aerodynamic drag. The mechanical properties of FRP composites degrades beyond certain temperature, depending primarily upon resin system and its glass transition temperature (Tg). In present work, the method of ring fabrication using filament winding is used to prepare test samples to experimentally test and evaluate apparent tensile strength with temperature of Carbon Epoxy composite. The tensile test at ambient is also done on specimens made from carbon Epoxy laminate using filament winding technique and are compared with ring test results.. The Glass Transition temperature (Tg) for Carbon Epoxy is also determined with Dry Scanning Calorimetry (DSC) techniqu

Scope, Nutritional Importance and Value Addition in Palmyrah (<em>Borassus flabellifer L.</em>): An Under Exploited Crop

Palmyrah palm has great economic potential and every part of the palm is useful in one way or the other is considered as ‘kalpaga tharu’. The palm is found growing widely in southern states of India. As the value addition in palmyrah is not standardized, the palmyrah products viz. tender fruit endosperm (nungu), neera, jaggery and tuber flour are not commercialized so far. Even though palmyrah is an economically important palm for its nutritional aspects, it has not received proper attention from the agricultural research workers, probably on account of the fact that it is very slow growing palm and mostly found in the wild state. In this context, knowing the physico-chemical properties and development of value added products and popularizing the same is essential

SRF is required for maintenance of astrocytes in non-reactive state in the mammalian brain

Astrocytes play several critical roles in the normal functioning of the mammalian brain, including ion homeostasis, synapse formation, and synaptic plasticity. Following injury and infection or in the setting of neurodegeneration, astrocytes become hypertrophic and reactive, a process termed astrogliosis. Although acute reactive gliosis is beneficial in limiting further tissue damage, chronic gliosis becomes detrimental for neuronal recovery and regeneration. Several extracellular factors have been identified that generate reactive astrocytes; however, very little is known about the cell-autonomous transcriptional mechanisms that regulate the maintenance of astrocytes in the normal non-reactive state. Here, we show that conditional deletion of the stimulus-dependent transcription factor, serum response factor (SRF) in astrocytes

3-Benzyl-6-benzyl­amino-1-methyl-5-nitro-1,2,3,4-tetra­hydro­pyrimidine

In the title compound, C19H22N4O2, the tetra­hydro­pyrimidine ring adopts an envelope conformation (with the N atom connected to the benzyl group representing the flap). This benzyl group occupies a quasi-axial position. The two benzyl groups lie over the tetra­hydro­pyridimidine ring. The amino group is a hydrogen-bond donor to the nitro group

6-Meth­oxy-N-methyl-3-nitro-4-nitro­methyl-4H-chromen-2-amine

In the title compound, C12H13N3O6, the dihydro­pyran ring adopts a near screw-boat conformation. The dihedral angle between the mean planes of the benzene and dihydro­pyran rings is 6.35 (5)°. An intra­molecular N—H⋯O hydrogen bond generates an S(6) motif, which stabilizes the mol­ecular conformation. In the crystal, weak inter­molecular C—H⋯O, N—H⋯O and C—H⋯π hydrogen bonds contribute to the stabilization of the packing

4-[4-(Diethyl­amino)­phen­yl]-N-methyl-3-nitro-4H-chromen-2-amine

In the title compound, C20H23N3O3, the dihydro­pyran ring adopts half-chair conformation. The chromene system makes a dihedral angle of 87.35 (5)° with the adjacent benzene ring. An intra­molecular N—H⋯O hydrogen bond generates an S(6) motif, which stabilizes the mol­ecular conformation. In the crystal, weak inter­molecular C—H⋯O hydrogen bonds contribute to the stabilization of the packing

SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

Reactive astrogliosis is a common pathological hallmark of CNS injury, infection, and neurodegeneration, where reactive astrocytes can be protective or detrimental to normal brain functions. Currently, the mechanisms regulating neuroprotective astrocytes and the extent of neuroprotection are poorly understood. Here, we report that conditional deletion of serum response factor (SRF) in adult astrocytes causes reactive-like hypertrophic astrocytes throughout the mouse brain. Thes