116 research outputs found

    Modeling and Compensation of Nonlinear Distortion in Horn Loudspeakers

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    Horn loaded compression drivers are widely used in the area where high sound pressure levels together with good directivity characteristics are needed. Major disadvantage of this kind of drivers is the considerable amount of nonlinear distortion. Due to the quite high air pressures in the driver the air is driven into its nonlinear range. This paper describes a technique to reduce the distortion caused by this phenomenon. Using a Digital Signal Processor (DSP), a feedforward compensation technique, based on an equivalent lumped parameter circuit, is implemented and tested in real–time in series with the loudspeaker. Measurement and simulation results are given. The overall conclusion is that a distortion reduction is obtained in the frequency span from 600 to 1050 Hz

    On the design of an image compression scheme based upon a priori knowledge about imaging system and image statistics

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    This contribution is about the design of an image compression scheme for near loss-less image compression of a restricted class of images and a specific application. The images are digital diagnostic X-ray images of the coronary vessels of the human heart. This paper proposes a novel compression scheme with a compression ratio of 8-10 with preservation of the diagnostic image quality. Central in our approach is the amount of information a trained and highly skilled observer i.e. the cardiologist is able discern at a given exposure and thus quantum noise level. The physics of the image detection process together with the a priori knowledge of the imaging system are the basis of the image statistics. Relevant elements of the human visual system complete the stochastic characterization of imaging process whereon the compression scheme is based. 1

    Digital compensation of nonlinear distortion in loudspeakers

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    The authors present a method to compensate for loudspeaker distortion in real time by nonlinear digital signal processing implemented on a digital signal processor (i.e., the TMS320C30 DSP). Based on the literature, an electrical equivalent circuit of an electrodynamic loudspeaker is developed, resulting in a linear lumped parameter model. The parameters in this model are matched with the measurements of a selected test loudspeaker. The linear model is extended to include nonlinear effects by developing the parameters as a function of the voice coil excursion of the loudspeaker in a Taylor series expansion. The resulting nonlinear system is described by a Volterra series. On the basis of this description, an inverse circuit is designed for the second-order nonlinear distortion. This circuit was implemented in real time on the DSP, using a high-level design and code generation system. Simulations and experiments are presente

    Haemodynamics in Different Flow Lumen Configurations of Customised Aortic Repair for Infrarenal Aortic Aneurysms

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    Objective: Customised aortic repair (CAR) is a new and minimally invasive technique for the endovascular treatment of abdominal aortic aneurysms (AAAs). The aneurysm is completely sealed with a non-contained, non-cross linked polymer, while a new flow lumen is created with balloons. For CAR, the haemodynamically most favourable balloon and flow lumen configuration has not been established before; therefore, four flow parameters were assessed in an in vitro model. Methods: Three in vitro balloon configurations were implanted in an in vitro AAA model; a configuration with crossing balloons (CC) and two parallel configurations (PC1 and PC2). These three models were consecutively placed in a flow system that mimics physiological flow conditions. Laser particle imaging velocimetry (PIV) was used to resolve spatial and temporal flow patterns during the cardiac cycle. In house built algorithms were used to analyse the PIV data for the computing of (i) flow velocity; (ii) vorticity; (iii) wall shear stress (WSS); and (iv) time averaged wall shear stress (TAWSS). Results: Suprarenal flow patterns were similar in all models. The CC showed a higher infrarenal velocity than PC1 and PC2 (38 cm/s vs. 23 cm/s vs. 23 cm/s), and a higher vorticity at the crossing of the lumens (CC: 337/s; PC1 127/s; PC2: 112/s). The lowest vorticity was observed in PC2, especially in the infrarenal neck (CC: 200/s; PC1 164/s; PC2: 98/s). Although WSS and TAWSS varied between configurations, values were the within non-pathological range. Conclusion: The flow lumens created by three balloon configurations used in an in vitro model of CAR have been studied, and resulted in different haemodynamics. The differences in velocity and lower vorticity, especially at the crossing section of the two balloons, showed that PC2 has favourable haemodynamics compared with the CC and PC1. Future research will be focused on the clinical applicability of CAR based on the PC2 design

    A 3D-printed anatomical pancreas and kidney phantom for optimizing SPECT/CT reconstruction settings in beta cell imaging using 111In-exendin

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    Contains fulltext : 165641.pdf (publisher's version ) (Open Access)BACKGROUND: Quantitative single photon emission computed tomography (SPECT) is challenging, especially for pancreatic beta cell imaging with 111In-exendin due to high uptake in the kidneys versus much lower uptake in the nearby pancreas. Therefore, we designed a three-dimensionally (3D) printed phantom representing the pancreas and kidneys to mimic the human situation in beta cell imaging. The phantom was used to assess the effect of different reconstruction settings on the quantification of the pancreas uptake for two different, commercially available software packages. METHODS: 3D-printed, hollow pancreas and kidney compartments were inserted into the National Electrical Manufacturers Association (NEMA) NU2 image quality phantom casing. These organs and the background compartment were filled with activities simulating relatively high and low pancreatic 111In-exendin uptake for, respectively, healthy humans and type 1 diabetes patients. Images were reconstructed using Siemens Flash 3D and Hermes Hybrid Recon, with varying numbers of iterations and subsets and corrections. Images were visually assessed on homogeneity and artefacts, and quantitatively by the pancreas-to-kidney activity concentration ratio. RESULTS: Phantom images were similar to clinical images and showed comparable artefacts. All corrections were required to clearly visualize the pancreas. Increased numbers of subsets and iterations improved the quantitative performance but decreased homogeneity both in the pancreas and the background. Based on the phantom analyses, the Hybrid Recon reconstruction with 6 iterations and 16 subsets was found to be most suitable for clinical use. CONCLUSIONS: This work strongly contributed to quantification of pancreatic 111In-exendin uptake. It showed how clinical images of 111In-exendin can be interpreted and enabled selection of the most appropriate protocol for clinical use

    Sustainability of Individual EndoAnchor Implants in Therapeutic Use to Treat Type Ia Endoleak After Endovascular Aneurysm Repair

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    Purpose: To investigate changes in penetration depths and angles of EndoAnchor implants with initially good penetration after therapeutic use in endovascular aneurysm repair. Materials and Methods: Patients were selected from the Aneurysm Treatment Using the Heli-FX Aortic Securement System Global Registry (ANCHOR; ClinicalTrials.gov identifier NCT01534819). Inclusion criteria were (1) EndoAnchor implantation to treat intraoperative or late type Ia endoleak and (2) at least 2 postoperative computed tomography angiography (CTA) scans. Exclusion criteria were the use of adjunct procedures. Based on these criteria, 54 patients (44 men) with 360 EndoAnchor implants were eligible for this analysis. Penetration depth of each EndoAnchor implant into the aortic wall was judged as (1) good (2-mm penetration), (2) borderline (</p

    Additional value of biomechanical indices based on CTa for rupture risk assessment of abdominal aortic aneurysms

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    Objective Biomechanics for rupture risk prediction in abdominal aortic aneurysms (AAA) are gaining popularity. However, their clinical applicability is still doubtful as there is lack of standardization. This study evaluates the added value of biomechanical indices in rupture risk assessment. Methods This study included 175 asymptomatic, 11 sAAA and 45 ruptured aneurysms. 3D-geome-tries were reconstructed using computer tomography angiographies. Subsequently, finite element models were made to calculate peak wall stress (PWS), peak wall rupture index (PWRI) and the rupture risk equivalent diameter (RRED). The indices were determined with a dedicated software to facilitate standardization. Results SAAAs showed a trend towards higher PWS, PWRI and RRED compared to asymptomatic AAAs, but PWS (22.0±5.8 vs. 33.4±15.8 N/cm2), PWRI (0.52±0.2 vs. 1.01±0.64), and RRED (65±60 vs. 98±51 mm) were significantly (p = 0.001) higher in ruptured. However, after diameter-matching no significant differences were seen. The ROC-curves for the maximum diameter and all biomechanical indices were similar but it slightly increased when diameter and biomechanical indices were combined. Conclusions This study showed no added value for biomechanical indices in AAA rupture risk assessment. Additionally, the difficulty of such an assessment increases. However, as symptomatic aneurysms show a trend towards higher biomechanical indices with similar diameters the indices may provide information about aneurysm growth and development

    Improvement of phosphorus availability by microbial phytase in broilers and pigs

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    Techniques have been developed to produce microbial phytase for addition to diets for simple-stomached animals, with the aim to improve phosphorus availability from phytate-P in plant sources. The activityof the crude microbial phytase showed pH optima at pH 5-5 and 2·5. The enzyme was able to degradephytate in vitro in soya-bean meal, maize and a liquid compound feed for pigs. When microbial phytasewas added to low-P diets for broilers the availability of P increased to over 60 % and the amount of Pin the droppings decreased by 50%. The growth rate and feed conversion ratio on the low-P dietscontaining microbial phytase were comparable to or even better than those obtained on control diets.Addition of microbial phytase to diets for growing pigs increased the apparent absorbability of P by24%. The amount of P in the faeces was 35% lower
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