Design and Implementation of Position Estimator Algorithm on Voice Coil Motor

Voice Coil Motors (VCMs) have been an inevitable element in the mechanisms that have been used for precise positioning in the applications like 3D printing., micro-stereolithography., etc. These voice coil motors translate in a linear direction and require a high accuracy position sensor that amounts for a major part in the budget. In this research work., an effort has been made to design and implement an algorithm that would predict the displacement of VCM and eliminate the need of high cost sensors. VCM was integrated with dSPACE DS1104 R&D controller via linear current amplifier (LCAM) which acts as a driver circuit for VCM. Sine input was given to VCM with various amplitude and frequency and the corresponding displacement is measured by using linear variable differential transformer (LVDT). The position estimator algorithm is also implemented at the same time on VCM and its output is compared with that of LVDT. It is observed that there is 97.8 % accuracy in between algorithm output and LVDT output. Further., PID controller is used in integration with the novel algorithm to minimize the error. The estimator algorithm is tested for various amplitudes and frequencies and it is found that it has a very good agreement of 99.2% with the actual displacement measured with the help of LVDT

Smart Waste Management System using IoT

With rapid increase in population, the issues related to sanitation with respect to garbage management are degrading immensely. It creates unhygienic conditions for the citizens in the nearby surrounding, leading to the spread of infectious diseases and illness. To avoid this problem, IoT based “Smart Waste Management” is the best and trending solution. In the proposed system, public dustbins will be provided with embedded device which helps in real time monitoring of level of garbage in garbage bins. The data regarding the garbage levels will be used to provide optimized route for garbage collecting vans, which will reduce cost associated with fuel. The load sensors will increase efficiency of data related to garbage level and moisture sensors will be used to provide data of waste segregation in a dust bin. The analysis of ceaseless data gathered will help municipality and government authorities to improve plans related to smart waste management with the help of various system generated reports

Evaluation Of Thermo Hydraulic Performance Of Passive And Compound Inserts

In the present investigation, the heat transfer and pressure drop performance of a tube in tube heat exchanger fitted with Bakelite helical screw tape and aluminum hemispherical cup shape with threaded core rod insert is experimentally reported for turbulent flow in individual and compound insertion cases. Performance is evaluated using water in the Reynolds number range of 8000 to 32000. For helical screw tape, the average Nusselt number ratios for augmented tube case to plain tube case (Nua/Nup) were found to be ranging between 2.51 – 2.7 along with average friction factor ratios (fa/ fp) ranging between 4.12 – 4.13. For cup shape inserts, the average Nusselt number ratios for augmented tube case to plain tube case (Nua/Nup) were reported between 1.38 – 1.62 along with friction factor ratios (fa/ fp) ranging between 4.93 – 5.44 . The average Nusselt number ratios (Nua/Nup) and friction factor ratios (fa/ fp) for two compound insertion cases are also reported by varying the cross-section of inserts for 1/3rd length of the heat exchanger and observed in the range of 2.26 – 2.65, and 4.06 – 4.8 respectively. For equal pumping power criteria, the average performance ratios (Nua/Nuc) are reported in the range of 1.02 -1.11 for helical screw tape, 0.6 – 0.67 for cup shape insert and 0.99 – 1.22 for two compound insertion caes

Participatory women’s groups and counseling through home visits to improve child growth in rural eastern India: protocol for a cluster randomised controlled trial

Background: Childhood stunting (low height-for-age) is a marker of chronic undernutrition and predicts children’s subsequent physical and cognitive development. An estimated 52 million children in India are stunted. There is a broad consensus on determinants of child undernutrition and interventions to address it, but a lack of operational research testing strategies to increase the coverage of these interventions in high burden areas. Our study aims to assess the impact, costeffectiveness, and scalability of a community intervention involving a government-proposed community-based worker to improve growth in children under two

AN OVERVIEW ON CARBON NANOTUBES

ABSTRACT: In different fields like semiconductors, field emission, conductive plastics, energy storage, conductive adhesives and connectors, molecular electronics, thermal materials carbon nanotubes are applicable. Carbon nanotubes are generally produced by three main techniques: arc discharge, laser ablation, chemical vapour deposition. In arc discharge, a vapour is created by an arc discharge between two carbon electrodes with or without catalyst. Nanotubes self-assemble from the resulting carbon vapour. In the laser ablation technique, a high-power laser beam impinges on a volume of carbon -containing feedstock gas (methane or carbon monoxide). At the moment, laser ablation produces a small amount of clean nanotubes, whereas arc discharge methods generally produce large quantities of impure material. In general, chemical vapour deposition (CVD) results in Multi Walled Nanotubes or poor quality Single Walled Nanotubes. The SWNTs produced with CVD have a large diameter range, which can be poorly controlled. But on the other hand, this method is very easy to scale up, what favours commercial production

Multiplex polymerase chain reaction for simultaneous quantitation of human nuclear, mitochondrial, and male Y-chromosome DNA: Application in human identification

Human forensic casework requires sensitive quantitation of human nuclear (nDNA), mitochondrial (mtDNA), and male Y-chromosome DNA from complex biomaterials. Although many such systems are commercially available, no system is capable of simultaneously quantifying all three targets in a single reaction. Most available methods either are not multiplex compatible or lack human specificity. Here, we report the development of a comprehensive set of human-specific, target-specific multiplex polymerase chain reaction (PCR) assays for DNA quantitation. Using TaqMan-MGB probes, our duplex qPCR for nDNA/mtDNA had a linear quantitation range of 100 ng to 1 pg, and our triplex qPCR assay for nDNA/mtDNA/male Y DNA had a linear range of 100-0.1 ng. Human specificity was demonstrated by the accurate detection of 0.05 and 5% human DNA from a complex source of starting templates. Target specificity was confirmed by the lack of cross-amplification among targets. A high-throughput alternative for human gender determination was also developed by multiplexing the male Y primer/probe set with an X-chromosome-based system. Background cross-amplification with DNA templates derived from 14 other species was negligible aside from the male Y assay which produced spurious amplifications from other nonhuman primate templates. Mainstream application of these assays will undoubtedly benefit forensic genomics. © 2004 Elsevier Inc. All rights reserved

Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure

BACKGROUND: Accumulating evidence suggests that the failing heart reprograms fuel metabolism toward increased utilization of ketone bodies and that increasing cardiac ketone delivery ameliorates cardiac dysfunction. As an initial step toward development of ketone therapies, we investigated the effect of chronic oral ketone ester (KE) supplementation as a prevention or treatment strategy in rodent heart failure models. METHODS: Two independent rodent heart failure models were used for the studies: transverse aortic constriction/myocardial infarction (MI) in mice and post-MI remodeling in rats. Seventy-five mice underwent a prevention treatment strategy with a KE comprised of hexanoyl-hexyl-3-hydroxybutyrate KE (KE-1) diet, and 77 rats were treated in either a prevention or treatment regimen using a commercially available β-hydroxybutyrate-(R)-1,3-butanediol monoester (DeltaG; KE-2) diet. RESULTS: The KE-1 diet in mice elevated β-hydroxybutyrate levels during nocturnal feeding, whereas the KE-2 diet in rats induced ketonemia throughout a 24-hour period. The KE-1 diet preventive strategy attenuated development of left ventricular dysfunction and remodeling post-transverse aortic constriction/MI (left ventricular ejection fraction±SD, 36±8 in vehicle versus 45±11 in KE-1; P=0.016). The KE-2 diet therapeutic approach also attenuated left ventricular dysfunction and remodeling post-MI (left ventricular ejection fraction, 41±11 in MI-vehicle versus 61±7 in MI-KE-2; P<0.001). In addition, ventricular weight, cardiomyocyte cross-sectional area, and the expression of ANP (atrial natriuretic peptide) were significantly attenuated in the KE-2-treated MI group. However, treatment with KE-2 did not influence cardiac fibrosis post-MI. The myocardial expression of the ketone transporter and 2 ketolytic enzymes was significantly increased in rats fed KE-2 diet along with normalization of myocardial ATP levels to sham values. CONCLUSIONS: Chronic oral supplementation with KE was effective in both prevention and treatment of heart failure in 2 preclinical animal models. In addition, our results indicate that treatment with KE reprogrammed the expression of genes involved in ketone body utilization and normalized myocardial ATP production following MI, consistent with provision of an auxiliary fuel. These findings provide rationale for the assessment of KEs as a treatment for patients with heart failure

Preparation and characterization of superhydrophobic surfaces based on hexamethyldisilazane-modified nanoporous alumina

Superhydrophobic nanoporous anodic aluminum oxide (alumina) surfaces were prepared using treatment with vapor-phase hexamethyldisilazane (HMDS). Nanoporous alumina substrates were first made using a two-step anodization process. Subsequently, a repeated modification procedure was employed for efficient incorporation of the terminal methyl groups of HMDS to the alumina surface. Morphology of the surfaces was characterized by scanning electron microscopy, showing hexagonally ordered circular nanopores with approximately 250 nm in diameter and 300 nm of interpore distances. Fourier transform infrared spectroscopy-attenuated total reflectance analysis showed the presence of chemically bound methyl groups on the HMDS-modified nanoporous alumina surfaces. Wetting properties of these surfaces were characterized by measurements of the water contact angle which was found to reach 153.2 ± 2°. The contact angle values on HMDS-modified nanoporous alumina surfaces were found to be significantly larger than the average water contact angle of 82.9 ± 3° on smooth thin film alumina surfaces that underwent the same HMDS modification steps. The difference between the two cases was explained by the Cassie-Baxter theory of rough surface wetting

An Ultra-High Discrimination Y Chromosome Short Tandem Repeat Multiplex DNA Typing System

In forensic casework, Y chromosome short tandem repeat markers (Y-STRs) are often used to identify a male donor DNA profile in the presence of excess quantities of female DNA, such as is found in many sexual assault investigations. Commercially available Y-STR multiplexes incorporating 12–17 loci are currently used in forensic casework (Promega's PowerPlex® Y and Applied Biosystems' AmpFlSTR® Yfiler®). Despite the robustness of these commercial multiplex Y-STR systems and the ability to discriminate two male individuals in most cases, the coincidence match probabilities between unrelated males are modest compared with the standard set of autosomal STR markers. Hence there is still a need to develop new multiplex systems to supplement these for those cases where additional discriminatory power is desired or where there is a coincidental Y-STR match between potential male participants. Over 400 Y-STR loci have been identified on the Y chromosome. While these have the potential to increase the discrimination potential afforded by the commercially available kits, many have not been well characterized. In the present work, 91 loci were tested for their relative ability to increase the discrimination potential of the commonly used ‘core’ Y-STR loci. The result of this extensive evaluation was the development of an ultra high discrimination (UHD) multiplex DNA typing system that allows for the robust co-amplification of 14 non-core Y-STR loci. Population studies with a mixed African American and American Caucasian sample set (n = 572) indicated that the overall discriminatory potential of the UHD multiplex was superior to all commercial kits tested. The combined use of the UHD multiplex and the Applied Biosystems' AmpFlSTR® Yfiler® kit resulted in 100% discrimination of all individuals within the sample set, which presages its potential to maximally augment currently available forensic casework markers. It could also find applications in human evolutionary genetics and genetic genealogy