259 research outputs found

    Spin Motion in Electron Transmission through Ultrathin Ferromagnetic Films Accessed by Photoelectron Spectroscopy

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    Ab initio and model calculations demonstrate that the spin motion of electrons transmitted through ferromagnetic films can be analyzed in detail by means of angle- and spin-resolved core-level photoelectron spectroscopy. The spin motion appears as precession of the photoelectron spin polarization around and as relaxation towards the magnetization direction. In a systematic study for ultrathin Fe films on Pd(001) we elucidate its dependence on the Fe film thickness and on the Fe electronic structure. In addition to elastic and inelastic scattering, the effect of band gaps on the spin motion is addressed in particular.Comment: 4 pages, 5 figure

    Systematic Review: Controlled Trials of Interventions to Improve Communication in Intensive Care

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    Background: Communication between families and providers in the intensive care unit (ICU) affects patient and family outcomes, and healthcare utilization. Recent research has tested interventions designed to improve communication quality and outcomes between providers and families of ICU patients. We conducted a systematic review of these studies. Methods: We searched MEDLINE, PsychInfo, Cochrane, and CINAHL from 1995 to July 2010. Included studies reported controlled clinical interventions designed to improve communication between providers and families of ICU patients aged 18 years or older. Investigators abstracted all selected studies to a standardized data collection instrument and completed a quality checklist based on recommendations from the CONSORT investigators. Results: 2841 titles were identified. 180 met criteria for full review and 21 articles of 16 distinct interventions met full inclusion criteria, of which 5 were randomized. Interventions studied included printed information, or structured family conferences with or without additional family support. Conferences aimed to communicate diagnosis and prognosis, elicit patient values, assess family understanding, and clarify goals of treatment. Printed information, palliative care or ethics consultation, or regular, structured communication by the usual ICU team reduced family distress, improved comprehension, and decreased use of intensive treatments. Conclusions: Moderate quality evidence supports printed information and structured communication by the usual ICU team, ethics consultation, or palliative care consultation to improve family emotional outcomes, and reduce ICU lengths of stay and treatment intensity. Evidence that these interventions reduce total costs is inconclusive. A comprehensive research agenda should ensure future study of a full range of patient-centered outcomes.Master of Public Healt

    Clean thermal decomposition of tertiary-alkyl metal thiolates to metal sulfides: Environmentally-benign, non-polar inks for solution-processed chalcopyrite solar cells

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    We report the preparation of Cu2S, In2S3, CuInS2 and Cu(In,Ga)S2 semiconducting films via the spin coating and annealing of soluble tertiary-alkyl thiolate complexes. The thiolate compounds are readily prepared via the reaction of metal bases and tertiary-alkyl thiols. The thiolate complexes are soluble in common organic solvents and can be solution processed by spin coating to yield thin films. Upon thermal annealing in the range of 200-400 ??C, the tertiary-alkyl thiolates decompose cleanly to yield volatile dialkyl sulfides and metal sulfide films which are free of organic residue. Analysis of the reaction byproducts strongly suggests that the decomposition proceeds via an SN1 mechanism. The composition of the films can be controlled by adjusting the amount of each metal thiolate used in the precursor solution yielding bandgaps in the range of 1.2 to 3.3 eV. The films form functioning p-n junctions when deposited in contact with CdS films prepared by the same method. Functioning solar cells are observed when such p-n junctions are prepared on transparent conducting substrates and finished by depositing electrodes with appropriate work functions. This method enables the fabrication of metal chalcogenide films on a large scale via a simple and chemically clear process.ope

    AKAPS act in a two-step mechanism of memory acquisition

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    Defining the molecular and neuronal basis of associative memories is based upon behavioral preparations that yield high performance due to selection of salient stimuli, strong reinforcement, and repeated conditioning trials. One of those preparations is the Drosophila aversive olfactory conditioning procedure where animals initiate multiple memory components after experience of a single cycle training procedure. Here, we explored the analysis of acquisition dynamics as a means to define memory components and revealed strong correlations between particular chronologies of shock impact and number experienced during the associative training situation and subsequent performance of conditioned avoidance. Analyzing acquisition dynamics in Drosophila memory mutants revealed that rutabaga (rut)-dependent cAMP signals couple in a divergent fashion for support of different memory components. In case of anesthesia-sensitive memory (ASM) we identified a characteristic two-step mechanism that links rut-AC1 to A-kinase anchoring proteins (AKAP)-sequestered protein kinase A at the level of Kenyon cells, a recognized center of olfactory learning within the fly brain. We propose that integration of rut-derived cAMP signals at level of AKAPs might serve as counting register that accounts for the two-step mechanism of ASM acquisition

    Delayed Hemolytic Transfusion Reaction in Sickle Cell Disease

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    Delayed hemolytic transfusion reactions (DHTR) are potentially life-threatening complications observed in patients with sickle cell disease. We review the clinical features, pathophysiology, laboratory evaluation, and management of this complication. It is important that DHTR be included in the differential diagnosis of acute pain episodes following a red blood cell transfusion in a patient with sickle cell disease

    Aging and Post-Intensive Care Syndrome–Family (PICS-F): A Critical Need for Geriatric Psychiatry

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    Postintensive care syndrome–family (PICS-F) describes the psychological symptoms that affect the family members of patients hospitalized in the intensive care unit (ICU) or recently discharged from the ICU. Geriatric psychiatrists should be concerned about PICS-F for several reasons. First, ICU hospitalization in older adults is associated with higher rates of cognitive and physical impairment compared with older adults hospitalized in non-ICU settings or dwelling in the community. This confers a special burden on the caregivers of these older ICU survivors compared with other geriatric populations. Second, as caregivers themselves age, caring for this unique burden can be more challenging compared with other geriatric populations. Third, evidence for models of care centered on patients with multimorbidity and their caregivers is limited. A deeper understanding of how to care for PICS and PICS-F may inform clinical practice for other geriatric populations with multimorbidity and their caregivers. Geriatric psychiatrists may play a key role in delivering coordinated care for PICS-F by facilitating timely diagnosis and interdisciplinary collaboration, advocating for the healthcare needs of family members suffering from PICS-F, and leading efforts within healthcare systems to increase awareness and treatment of PICS-F. This clinical review will appraise the current literature about the impact of critical illness on the family members of ICU survivors and identify crucial gaps in our knowledge about PICS-F among aging patients and caregivers

    Trichopria anastrephae as a Biological Control Agent of Drosophila suzukii in Strawberries.

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    Abstract: In South America, the resident pupal parasitoid Trichopria anastrephae Costa Lima (Hymenoptera: Diapriidae) is a potential biological control agent of the pest Drosophila suzukii Matsumura (Diptera: Drosophilidae). In the present study, we (1) examined the behavior of T. anastrephae towards diferent host (D. suzukii) and host-substrate (strawberry) cues in choice and non-choice bioassays in laboratory, and (2) examined the density-dependent parasitism of T. anastrephae in D. suzukiiinfested strawberries in a greenhouse. When given a choice, female parasitoids walked longer over chambers with fruits infested with eggs, larvae, or pupae of D. suzukii, when compared to healthy uninfested strawberries, and over overripe fruits when compared to unripe or ripe fruits. In the greenhouse assay, we observed an increase in parasitism and a decrease in the number of D. suzukii emerging per fruit with an increase in the number of parasitoids released. Our results allow a better understanding of the behavior and parasitism of T. anastrephae in D. suzukii-infested strawberries and provide useful data for potential biological control programs using this parasitoid

    Prolonged rather than hasty decision-making in schizophrenia using the box task. Must we rethink the jumping to conclusions account of paranoia?

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    Accepted manuscript version, licensed CC BY-NC-ND 4.0. Jumping to conclusions (JTC) is the best established cognitive bias in schizophrenia and is increasingly targeted in interventions aimed to improve positive symptoms. To address shortcomings of the standard measure to capture JTC, the beads task, we developed a new variant—the box task—which was subsequently validated in people with elevated psychotic-like experiences. For the first time, the box task was administered in a sample of individuals with manifest schizophrenia. We hypothesized that patients with schizophrenia would display an elevated JTC bias relative to controls. Method - We recruited a large sample of 101 patients with schizophrenia and matched them to an online sample recruited from the general population. In the box task, participants must decide which of two kinds of colored balls are presented more often. Participants are told that the task may end prematurely, and that task performance will be counted as an error if no decision had been made before that point. The primary measure was the number of draws to decision (DTD), where fewer DTD corresponds to greater JTC. Results - In contrast to expectations, participants with schizophrenia showed significantly higher DTD (i.e., reduced JTC). Consistent with our previous findings, patients also displayed a lowered decision threshold compared to controls. Response confidence for the final decision was lower in patients and correlated with self-esteem and positive symptoms. While there was evidence that previous knowledge of the box task lowered DTD, exclusion of participants with experience on the box task did not substantially change results. Discussion - The study fits a growing body of experiments casting doubt on the generalizability of the JTC effect in schizophrenia across different tasks. While the study tentatively supports a liberal acceptance account of psychosis, caution is warranted and we recommend that research should explore and control for potentially important mediators (e.g., task difficulty, stress, test-taking attitudes)

    Reproductive Biology of Trichopria anastrephae (Hymenoptera: Diapriidae), a Biological Control Agent of Drosophila suzukii (Matsumura) (Diptera: Drosophilidae).

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    Abstract: Hymenopteran parasitoids, like any other insect, employ strategies to ensure their reproduction. Understanding these strategies is important for ecological purposes, but also to improve mass rearing of biological control agents. Here, we describe mating strategies used by the pupal parasitoid Trichopria anastrephae Lima (Hymenoptera: Diapriidae), a potential biocontrol agent, that has been considered for augmentative releases for management of the invasive pest species Drosophila suzukii (Matsumura) (Diptera: Drosophilidae). We studied the emergence pattern of males and females of T. anastrephae and the efects of parental ae on ofspring number and sex ratio. Polygamy was also studied and its efects on parasitism and ofspring production were described. Adults from this species emerge in the frst hours of photophase, and males emerge before females, demonstrating that T. anastrephae is a protandrous species. Parasitoid age when frst mated infuences the parasitism and sex ratio. Younger females result in a higher number of ofspring (8.16 parasitoids/day), while older males result in a more female-biased sex ratio of ofspring (64% females). Both males and females are polygamic, and the order in which a female is mated by the male afects parasitism, viability of parasitized pupae, and sex ratio of ofspring, with the frst female performing the highest parasitism and sex ratio (63.83 and 61% of females, respectively), but the lowest viability (92.92%). Females that are allowed to mate multiple times generate lower numbers of ofspring (113.05 parasitoids) when compared to virgin or single-mated females (135.20 and 130.70 parasitoids, respectively), but the highest sex ratio (49% of females). Data present in this study and how it can be used to improve parasitoid rearing and feld releases of T. anastrephae, in biological control programs for D. suzukii are discussed

    The Facilitated Values History: Helping Surrogates Make Authentic Decisions for Incapacitated Patients with Advanced Illness

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    Many patients who develop incapacitating illness have not expressed clear treatment preferences. Therefore, surrogate decision makers are asked to make judgments about what treatment pathway is most consistent with the patient’s values. Surrogates often struggle with such decisions. The difficulty arises because answering the seemingly straightforward question, “What do you think the patient would choose?” is emotionally, cognitively, and morally complex. There is little guidance for clinicians to assist families in constructing an authentic picture of the patient’s values and applying them to medical decisions, in part because current models of medical decision making treat the surrogate as the expert on the patient’s values and the physician as the expert on technical medical considerations. However, many surrogates need assistance in identifying and working through the sometimes conflicting values relevant to medical decisions near the end of life. We present a framework for clinicians to help surrogates overcome the emotional, cognitive, and moral barriers to high-quality surrogate decision making for incapacitated patients
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