Comparision of Severity of Non-Cystic Fibrosis Bronchietasis Patients by the Two Prognostic Scores- Faced and BSI and Exacerbation Frequency over One Year Follow Up

BACK GROUND: Bronchiectasis is chronic respiratory disease defined pathologically by irreversible progressive dilatation and destruction of bronchi, so it requires a multidimensional scoring system to properly assess the severity. AIM OF THE STUDY: To compare the results of the assessment of the Non Cystic fibrosis Bronchiectasis (NCFB) severity by two validated scores, FACED score and the Bronchiectasis Severity Index (BSI) and Exacerbation frequency over follow up of one year METHODS: A Prospective observational study including 100 patients with NCFB was done. After exclusion and inclusion criteria underwent severity scoring by both FACED(five variables) and BSI(9variables), the same patients were followed up for a period of one year,in which exacerbations leading to hospitalisation noted. RESULTS: In FACED score,out of 100, we found 44 with mild,37 with moderate and 19 with severe bronchiectasis. The mean was 2.71;BSI reveals, the frequency of patients with low, intermediate and high BSI score was 33, 26 and 41 respectively. The mean was 7.18. The mean score of BSI was more than FACED which is found statistically significant with P value of 3 exacerbations have high BSI score. CONCLUSION: Prior excerbations was considered to be strongest predictor of morbidity which explains, this study found BSI as better predictor of bronchiectasis severity than FACED and those with high BSI score had more exacerbations leading to hospitalisation during one year follow up

ROLE BASED SECURED ACCESS OF DATA IN CLOUDS

In mobile wireless sensor network, coverage and energyCloud computing is a type of internet-based computing that provides shared computer processing resources and data to computers and other devices on demand. It is a model for enabling ubiquitous, on-demand access to a shared pool of configurable computing resources e.g., computer networks, servers, storage, applications and services, which can be rapidly provisioned and released with minimal management effort. Attribute-based access control defines an access control paradigm whereby access rights are granted to users through the use of policies which combine attributes together. The policies can use any type of attributes such as user attributes, resource attributes, object and environment attributes etc. This model supports Boolean logic, in which rules contain "if-then" statements about who is making the request, the resource and the action. The main problem in attribute–based access control is not having user-centric approach for authorization rules. In ABAC model role hierarchy and object hierarchy is not achieved and restriction in level of expressiveness in access control rules.Secured role-based access control allows managing authorization based on rule-based approach where rules are under the control of data owner and provides enriched role-based expressiveness including role and object hierarchies. Data user without the knowledge of data owner cannot use the cloud server where privilege is provided to data user by data owner. Access control computations are delegated to the cloud service provider, being this not only unable to access the data, but also unable to release it to unauthorized parties. A identity-based proxy re-encryption scheme has been used in order to provide a comprehensive and feasible solution for data centric-approach. Semantic web technologies have been exposed for the representation and evaluation of the authorization model

Modified Pipelining Hybridization of Job Shop Scheduling

Hybridization involves generally genetic algorithm in a stage .Here instead of genetic algorithm,metaheuristics method Local search method, is applied as primary search routine, for tacklingcombinatorial search and optimization problems.The dispatching rule LPT is applied first, servingas a preprocessor. The local search methods are works on the iterative exploration of a solutionspace: at each iteration a local search algorithm start search from one solution to one of itsneighbor. The method is analysis the job shop bench mark problems. The comparison of theperformance measure is evaluated

Comparative In-vitro Anthelmintic Activity of the Latex of Ficus religinosa, Ficus elastica and Ficus bengalensis

The World Health Organization estimates that a staggering two billion people harbor parasitic worm infections. Parasitic worms also infect livestock and crops, affecting food production with a resultant economic impact. The three plants present in the study are Ficus religinosa, Ficus elastica and Ficus bengalensis. They belong to the family Moraceae and are traditionally used for various diseases. Our aim was to investigate the anthelmintic activity of the latex of three plants. The latex of the plants was taken for anthelmintic activity against Indian earthworm Pheritima posthuma. Various species of the ficus latex was tested and results were expressed in terms of time for paralysis and time for death of worms. Metronidazole (10mg/ml) was used as a reference standard and distilled water as a control group. From the results of this study found that the three plants possess anthelmintic activity but Ficus religinosa shows more activities compared to others.Key words: F.religinosa, F.elastica, F.bengalensis, Metronidazole, Anthelmintic activity, latex B.N. Vedha Hari et al. Comparative In-vitro Anthelmintic Activity of the Latex of Ficus religinosa, Ficus elastica and Ficus bengalensis. J Phytol 3/3 (2011) 26-30

Evaluation of Antiproliferative Activity of Red Sorghum Bran Anthocyanin on a Human Breast Cancer Cell Line (MCF-7)

Breast cancer is a leading cause of death in women worldwide both in the developed and developing countries. Thus effective treatment of breast cancer with potential antitumour drugs is important. In this paper, human breast cancer cell line MCF-7 has been employed to evaluate the antiproliferative activity of red sorghum bran anthocyanin. The present investigation showed that red sorghum bran anthocyanin induced growth inhibition of MCF-7 cells at significant level. The growth inhibition is dose dependent and irreversible in nature. When MCF-7 cells were treated with red sorghum bran anthocyanins due to activity of anthocyanin morphological changes were observed. The morphological changes were identified through the formation of apoptopic bodies. The fragmentation by these anthocyanins on DNA to oligonuleosomal-sized fragments, is a characteristic of apoptosis, and it was observed as concentration-dependent. Thus, this paper clearly demonstrates that human breast cancer cell MCF-7 is highly responsive by red sorghum bran anthocyanins result from the induction of apoptosis in MCF-7 cells

Evaluation of the effect of magnesium in combination with organic manures on the growth and yield attributes and yield of cotton (Gossypium hirsutum L.) inTypic Ustropept

Cotton is India's most significant commercial crop and has a significant role in the agricultural economics of the nation. A field experiment was conducted in a farmer’s field located in Achchandavilthan village of Srivillipudhur block, Virudhunager District, from 28-Aug 2019 to Jan, 2020 to evaluate the response of cotton to foliar and soil application of magnesium combination with organic manures on the growth and yield attributes and yield of cotton in magnesium deficient soil. The soil was categorized as “Moderately deep clay Typic Ustropept, and medium N, P and high K content, in a randomized block design with fifteen treatments and three replications. The results revealed that the application of MgSO4 at a rate of 50 kg ha-1 along with 250 kg vermicompost for 30 days (1:5 ratio) at critical stages of crop growth along with the Soil Test Crop Response (STCR) based N,P2O5 and K2O RDF registered the maximum plant height at all three stages (40,70 and harvest) of crop growth (94.7, 122.3 and 222.2 cm), number of monopodial branches plant-1 (33.4), number of sympodial branches plant-1(73.1), numbers of boll plant-1 (48.3), boll weight (3.9 g), and seed cotton yield (26.2 q ha-1). This was followed by treatment (T9) MgSO4 at a rate of 50 kg ha-1 incubated with 500 kg FYM for 30 days (1:10 ratio) along with STCR) based N,P2O5 and K2O RDF and the lowest treatment receiving the recommended dose of N, P2O5 and K2O alone (80:40:40 kg ha1). It was revealed that natural chelated fertilizer prepared from MgSO4 incubated with organic manures for 30 days significantly improved the growth and yield of cotton

Broad thumb-hallux syndrome: A rare congenital disorder

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Agricultural bio-waste recycling through efficient microbial consortia

In India and other countries, rice straw, a byproduct of rice production, is burned in enormous amounts, which contributes to environmental pollution and climate change by releasing greenhouse gases viz., CO2, N2O, CH4, into the atmosphere. This study aimed to accelerate the degradation of this enormous amount of agricultural biomass via microbial inoculants. Four treatments—rice straw (RS), rice straw plus water (RSW), rice straw plus water plus Pusa decomposer (RSWF), and rice straw plus water plus Tamil Nadu Agricultural University (TNAU) biomineralizer (RSWB) were used in the current investigation. The study's findings demonstrated that rice straw treated with microorganisms decomposed more quickly than RS and RSW treatments. According to EDAX spectra of elemental composition, the carbon content of rice straw in the RS, RSW, RSWF, and RSWB treatments was 33.66%, 29.75%, 13.33%, and 20.65% w/w, respectively. The RSWF treatment of rice straw was found to have the highest nitrogen concentration (0.64% w/w), followed by RSWB (0.61% w/w), RSW (0.45%) w/w, and RS (0.43% w/w). Treatments RSWF and RSWB had lower C/N ratios 20.83, and 33.85, respectively, than that RSW (66.11) and RS (78.28). The RSWF and RSWB treatments' porous, distorted, and rough surface structures provided further evidence that both microbial consortia could decompose rice straw more quickly than the RSW and RS treatments. Therefore, the results of this study imply that rice straw could be added to the soil to improve soil fertility for sustainable crop production rather than being burned

Incidence of respiratory infections and its correlation with smoke exposure among infants from an urban field practice area in Tamil Nadu

Background: Children’s acute lower respiratory infections are most prevalent among new-born. Clinical evaluation and symptoms help to establish the connection between smoke exposure and acute respiratory tract infection (ARTI). Furthermore, there is proof that exposing children to coal smoke considerably increases their risk of developing ARTI. Aims and Objectives: This study was designed to estimate the incidence of respiratory tract infection (RTI) among selected cohort of infants in urban field practice area of Tamil Nadu and to correlate the incidence of RTIs with smoke practices. Materials and Methods: In Tamil Nadu’s urban field practice area, a cohort study of infants was done. A house-to-house survey was conducted and information was gathered among 150 newborns who were tracked after being selected as a period sample based on inclusion criteria at a 15* visit. Numerous data on ARI episodes, housing circumstances, and smoke exposure were gathered and correlated. Software such as Epi info and SPSS version 22 were used to analye data. Results: The incidence of TI was calculated to be 1.7 episodes per 100 person days and 4.7 on average among the 150 newborns chosen. Nearly 48% of people lived in huts, 84% had indoor kitchens, and 75% cooked with gas. Infants who appeared to regularly be exposed to passive smoking have a little increase in the incidence of mean RTI bouts. Conclusion: The additional hospital admissions, which are entirely preventable, place a heavy load on the public health system. It is evident that new initiatives are required to stop infants from being exposed to passive smoke during and after pregnancy. Improving international Electrotechnical commission activities play an active role is reducing incidence of RTIs among infants. Intensified educational interventions on ill effects of indoor and outdoor smoke, passive smoking helps in addressing the issue