Trapped Ar isotopes in meteorite ALH 84001 indicate Mars did not have a thick ancient atmosphere

Water is not currently stable in liquid form on the martian surface due to the present mean atmospheric pressure of ∼7 mbar and mean global temperature of ∼220 K. However, geomorphic features and hydrated mineral assemblages suggest that Mars’ climate was once warmer and liquid water flowed on the surface. These observations may indicate a substantially more massive atmosphere in the past, but there have been few observational constraints on paleoatmospheric pressures. Here we show how the [superscript 40]Ar/[superscript 36]Ar ratios of trapped gases within martian meteorite ALH 84001 constrain paleoatmospheric pressure on Mars during the Noachian era [∼4.56–3.8 billion years (Ga)]. Our model indicates that atmospheric pressures did not exceed ∼1.5 bar during the first 400 million years (Ma) of the Noachian era, and were <400 mbar by 4.16 Ga. Such pressures of CO[subscript 2] are only sufficient to stabilize liquid water on Mars’ surface at low latitudes during seasonally warm periods. Other greenhouse gases like SO[superscript 2] and water vapor may have played an important role in intermittently stabilizing liquid water at higher latitudes following major volcanic eruptions or impact events.United States. National Aeronautics and Space Administration. Mars Fundamental Research Program (Grant MFRP05-0108)Ann and Gordon Getty Foundatio

Radiometric age constraints for glacial terminations IX and VII

Buried sedimentary aggradational sections deposited between 800 ka and 600 ka in the Tiber River coastal alluvial plain have been studied using borecores from around Rome. 40Ar/39Ar ages on sanidine and/or leucite from intercalated tephra layers and paleomagnetic investigation of clay sections provide geochronological constraints on the timing of aggradation of two of these alluvial sections, and demonstrate that they were deposited in response to eustatic sea level rise caused by glacial terminations IX and VII. 40Ar/39Ar age data indicate ages of 802 ± 8 ka and 649 ± 3 ka for glacial terminations IX, and VII, respectively, providing a rare test, beyond the range of U-series dating for corals and speleothems (~500 ka), of the astronomically calibrated timescale developed for oxygen isotope records from deep sea cores

Tephrochronology in faulted Middle Pleistocene tephra layer in the Val d’Agri area (Southern Italy)

The High Agri River Valley is a Quaternary Basin located along the hinge of the Southern Apennines fold-andthrust belt. The inner margin of the orogen has been affected by intense transtensional and normal faulting, which accompanied vigorous volcanism during the Quaternary. Marker tephra layers are distributed across the whole of Southern Italy and provide a powerful tool to constrain both the size of eruptions and the regional activity of extensional faults controlling basin evolution. Paleoseismological trenching within the Monti della Maddalena range, that borders the Agri River Valley to the south-west, has exposed a faulted stratigraphic sequence and recovered a 10 cm thick tephra layer involved in deformation. This is the first tephra horizon recognized in the high Agri Valley, which, based on the stratigraphic study of the trench, lies in a primary position. 40Ar/39Ar dating constrain its age to 266 ka and provide an important marker for the Middle Pleistocene tephrochronology of the region. Together with dating, geochemical analysis suggests a possible volcanic source in the Campanian region

40Ar/39Ar and 14C geochronology of the Albano maar deposits: Implications for 2 defining the age and eruptive style of the most recent explosive activity at Colli 3 Albani Volcanic District, Central Italy

New 40Ar/39Ar and 14C ages have been found for the Albano multiple maar pyroclastic units and underlying 25 paleosols to document the most recent explosive activity in the Colli Albani Volcanic District (CAVD) near 26 Rome, Italy, consisting of seven eruptions (Albano 1 27 ^ = ^ oldest). Both dating methodologies have been applied on several proximal units and on four mid-distal fall/surge deposits, the latter correlated, according to two 28 current different views, to either the Albano or the Campi di Annibale hydromagmatic center. The 40Ar/39Ar 29 ages on leucite phenocrysts from the mid-distal units yielded ages of ca. 72 ka, 73 ka, 41 ka and 36 ka BP, 30 which are indistinguishable from the previously determined 40Ar/39Ar ages of the proximal Albano units 1, 2, 31 5 and 7, thus confirming their stratigraphic correspondence. 32 Twenty-one 14C ages of the paleosols beneath Albano units 3, 5, 6 and 7 were found for samples collected 33 from 13 proximal and distal sections, some of which were the same sections sampled for 40Ar/39Ar 34 measurements. The 14C ages were found to be stratigraphically inconsistent and highly scattered, and were 35 systematically younger than the 40Ar/39Ar ages, ranging 36 ^ from 35 ka ^ to 3 ka. Considering the significant consistence of the 40Ar/39Ar chronological framework, we interpret the scattered and contradictory 14C ages 37 to be the result of a variable contamination of the paleosols by younger organic carbon deriving from the 38 superficial soil horizons. 39 These results suggest that multiple isotopic systems anchored to a robust stratigraphic framework may need 40 to be employed to determine accurately the geochronology of the CAVD as well as other volcanic districts. 4

Voltage rectification by a SQUID ratchet

We argue that the phase across an asymmetric dc SQUID threaded by a magnetic flux can experience an effective ratchet (periodic and asymmetric) potential. Under an external ac current, a rocking ratchet mechanism operates whereby one sign of the time derivative of the phase is favored. We show that there exists a range of parameters in which a fixed sign (and, in a narrower range, even a fixed value) of the average voltage across the ring occurs, regardless of the sign of the external current dc component.Comment: 4 pages, 4 EPS figures, uses psfig.sty. Revised version, to appear in Physical Review Letters (26 August 1996

Structural Evolution of a Composite Middle to Lower Crustal Section: The Sierra de Pie de Palo, Northwest Argentina

The Sierra de Pie de Palo of northwest Argentina preserves middle to lower crustal metamorphic rocks that were penetratively deformed during Ordovician accretion of the Precordillera terrane to the Gondwana margin. New structural, petrologic, and geochronologic data from a 40 km structural transect reveals that the Sierra de Pie de Palo preserves a middle to lower crustal ductile thrust complex consisting of individual structural units and not an intact ophiolite and cover sequence. Top-to-the-west thrusting occurred intermittently on discrete ductile shear zones from ∼515 to ∼417 Ma and generally propagated toward the foreland with progressive deformation. Ordovician crustal shortening and peak metamorphic temperatures in the central portion of the Sierra de Pie de Palo were synchronous with retro-arc shortening and magmatic flare-up within the Famatina arc. Accretion of the Precordillera terrane resulted in the end of arc flare-up and the onset of synconvergent extension by ∼439 Ma. Continued synextensional to postextensional convergence was accommodated along progressively lower grade shear zones following terrane accretion and the establishment of a new plate margin west of the Precordillera terrane. The results support models of Cordilleran orogens that link voluminous arc magmatism to periods of regional shortening. The deformation, metamorphic, and magmatic history within the Sierra de Pie de Palo is consistent with models placing the region adjacent to the Famatina margin in the middle Cambrian and not as basement to the Precordillera terrane

40Ar/39Ar ages of CAMP in North America: implications for the Triassic-Jurassic boundary and the 40K decay constant bias

The Central Atlantic magmatic province (CAMP) is one of the largest igneous provinces on Earth (>107 km²) and spanning four continents. Recent high-precision 40Ar/39Ar dating of mineral separates has provided important constraints on the age, duration, and geodynamic history of CAMP. Yet, the North American CAMP is strikingly under-represented in this dating effort. Here we present 13 new statistically robust plateau, mini-plateau and isochron ages obtained on plagioclase and sericite separates from lava flows from the Fundy (n = 10; Nova Scotia, Canada) and Hartford and Deerfield (n = 3; U.S.A.) basins. Ages mostly range from 198.6 ± 1.1 to 200.1 ± 1.4 Ma (2σ), with 1 date substantially younger at 190.6 ± 1.0 Ma. Careful statistical regression shows that ages from the upper (199.7.0 ± 1.5 Ma) and bottom (200.1 ± 0.9 Ma) units of the lava pile in the Fundy basin are statistically indistinguishable, confirming a short duration emplacement (<< 1.8 Ma; ≤1 Ma). Three ages obtained on the Hartford (198.6 ± 2.0 Ma and 199.8 ± 1.1 Ma) and Deerfield (199.3 ± 1.2 Ma) basins were measured on sericite from the upper lava flow units. We interpret these dates as reflecting synemplacement hydrothermal activity within these units. Collectively, CAMP ages gathered so far suggest a short duration of the main magmatic activity (2-3 Ma), but also suggest the possibility of a temporal migration of the active magmatic centers from north to south. Such a migration challenges a plume model that would postulate a radial outward migration of the magmatism and is more compatible with other models such as the supercontinent global warming hypothesis. When compared to the age of the Triassic-Jurassic boundary, the filtered CAMP age database suggests that the onset of the magmatic activity precedes the limit by at least few hundred thousand years, therefore suggesting a causal relationship between CAMP and the end of Triassic mass extinction. An age at 191 Ma possibly suggests a minor CAMP late tailing activity (190-194 Ma) which has already observed for dykes and sills in Africa and Brazil. We speculate that, if real, this late activity can be due to a major extensional event, possibly heralding the oceanisation process at ~190 Ma. Comparison between high quality U/Pb and 40Ar/39Ar ages of pegmatite lenses from the North Mountain basalts confirms a ~1% bias between the two chronometers. This discrepancy is likely attributed to the miscalibration of the 40K decay constants, in particular the electron capture branch

Castration-induced downregulation of SPARC in stromal cells drives neuroendocrine differentiation of prostate cancer

Fatal neuroendocrine differentiation (NED) of castration-resistant prostate cancer is a recurrent mechanism of resistance to androgen deprivation therapies (ADT) and antiandrogen receptor pathway inhibitors (ARPI) in patients. The design of effective therapies for neuroendocrine prostate cancer (NEPC) is complicated by limited knowledge of the molecular mechanisms governing NED. The paucity of acquired genomic alterations and the deregulation of epigenetic and transcription factors suggest a potential contribution from the microenvironment. In this context, whether ADT/ARPI induces stromal cells to release NED-promoting molecules and the underlying molecular networks are unestablished. Here, we utilized transgenic and transplantable mouse models and coculture experiments to unveil a novel tumor-stroma cross-talk that is able to induce NED under the pressure of androgen deprivation. Castration induced upregulation of GRP78 in tumor cells, which triggers miR29-b-mediated downregulation of the matricellular protein SPARC in the nearby stroma. SPARC downregulation enabled stromal cells to release IL6, a known inducer of NED. A drug that targets GRP78 blocked NED in castrated mice. A public, human NEPC gene expression dataset showed that Hspa5 (encoding for GRP78) positively correlates with hallmarks of NED. Finally, prostate cancer specimens from patients developing local NED after ADT showed GRP78 upregulation in tumor cells and SPARC downregulation in the stroma. These results point to GRP78 as a potential therapeutic target and to SPARC downregulation in stromal cells as a potential early biomarker of tumors undergoing NED

The Volsci Volcanic Field (central Italy). Eruptive history, magma system and implications on continental subduction processes.

Here, we report on the Quaternary Volsci Volcanic Field (VVF, central Italy). In light of new 40Ar/39Ar geochronological data and compositional characterization of juvenile eruptive products, we refine the history of VVF activity, and outline the implications on the pre-eruptive magma system and the continental subduction processes involved. Different from the nearby volcanic districts of the Roman and Campanian Provinces, the VVF was characterized by small-volume (0.01–0.1 km3) eruptions from a network of monogenetic centers (mostly tuff rings and scoria cones, with subordinate lava occurrences), clustered along high-angle faults of lithospheric depth. Leucite-bearing, high-K (HKS) magmas (for which we report for the first time the phlogopite phenocryst compositions) mostly fed the early phase of activity (∼761–539 ka), then primitive, plagioclase-bearing (KS) magmas appeared during the climactic phase (∼424–349 ka), partially overlapping with HKS ones, and then prevailed during the late phase of activity (∼300–231 ka). The fast ascent of primitive magma batches is typical of a tectonically controlled volcanic field, where the very low magma flux is a passive byproduct of regional tectonic strain. We suggest that the dominant compressive stress field acting at depth was accompanied by an extensional regime in the upper crust, associated with the gravity spreading of the Apennine chain, allowing the fast ascent of magma from the mantle source with limited stationing in shallow reservoirs

Dynamic ordering and frustration of confined vortex rows studied by mode-locking experiments

The flow properties of confined vortex matter driven through disordered mesoscopic channels are investigated by mode locking (ML) experiments. The observed ML effects allow to trace the evolution of both the structure and the number of confined rows and their match to the channel width as function of magnetic field. From a detailed analysis of the ML behavior for the case of 3-rows we obtain ({\it i}) the pinning frequency $f_p$, ({\it ii}) the onset frequency $f_c$ for ML ($\propto$ ordering velocity) and ({\it iii}) the fraction $L_{ML}/L$ of coherently moving 3-row regions in the channel. The field dependence of these quantities shows that, at matching, where $L_{ML}$ is maximum, the pinning strength is small and the ordering velocity is low, while at mismatch, where $L_{ML}$ is small, both the pinning force and the ordering velocity are enhanced. Further, we find that $f_c \propto f_p^2$, consistent with the dynamic ordering theory of Koshelev and Vinokur. The microscopic nature of the flow and the ordering phenomena will also be discussed.Comment: 10 pages, 7 figure, submitted to PRB. Discussion has been improved and a figure has been adde