388 research outputs found

    Una experiencia de Inglés en la zona rural

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    Esta experiencia rural surgió en un intento de ofrecer a un grupo de personas alejadas de las ventajas del mundo urbano la posibilidad de conocer un idioma diferente al impuesto a los alumnos del colegio. Daba igual la edad: todos eran aceptados, porque en el ámbito rural la labor del enseñante va más allá de las cuatro paredes de su clase. El éxito o no de los resultados depende de lo que se evalúe: según los componentes del "Curso de Investigación e Interacción en el Aula" (ICE de la U. de Alcalá, en la Escuela de Profesorado de Guadalajara) y teniendo en cuenta el diseño que se realizó, la valoración no puede ser más que positiva

    Una experiencia de Inglés en la zona rural

    Get PDF
    Esta experiencia rural surgió en un intento de ofrecer a un grupo de personas alejadas de las ventajas del mundo urbano la posibilidad de conocer un idioma diferente al impuesto a los alumnos del colegio. Daba igual la edad: todos eran aceptados, porque en el ámbito rural la labor del enseñante va más allá de las cuatro paredes de su clase. El éxito o no de los resultados depende de lo que se evalúe: según los componentes del "Curso de Investigación e Interacción en el Aula" (ICE de la U. de Alcalá, en la Escuela de Profesorado de Guadalajara) y teniendo en cuenta el diseño que se realizó, la valoración no puede ser más que positiva

    Critical and Near-Critical Branching Processes

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    Scale-free dynamics in physical and biological systems can arise from a variety of causes. Here, we explore a branching process which leads to such dynamics. We find conditions for the appearance of power laws and study quantitatively what happens to these power laws when such conditions are violated. From a branching process model, we predict the behavior of two systems which seem to exhibit near scale-free behavior--rank-frequency distributions of number of subtaxa in biology, and abundance distributions of genotypes in an artificial life system. In the light of these, we discuss distributions of avalanche sizes in the Bak-Tang-Wiesenfeld sandpile model.Comment: 9 pages LaTex with 10 PS figures. v.1 of this paper contains results from non-critical sandpile simulations that were excised from the published versio

    Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

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    Understanding the structure-function relationships at cellular, circuit, and organ-wide scale requires 3D anatomical and phenotypical maps, currently unavailable for many organs across species. At the root of this knowledge gap is the absence of a method that enables whole-organ imaging. Herein, we present techniques for tissue clearing in which whole organs and bodies are rendered macromolecule-permeable and optically transparent, thereby exposing their cellular structure with intact connectivity. We describe PACT (passive clarity technique), a protocol for passive tissue clearing and immunostaining of intact organs; RIMS (refractive index matching solution), a mounting media for imaging thick tissue; and PARS (perfusion-assisted agent release in situ), a method for whole-body clearing and immunolabeling. We show that in rodents PACT, RIMS, and PARS are compatible with endogenous-fluorescence, immunohistochemistry, RNA single-molecule FISH, long-term storage, and microscopy with cellular and subcellular resolution. These methods are applicable for high-resolution, high-content mapping and phenotyping of normal and pathological elements within intact organs and bodies

    Universal 1/f Noise from Dissipative SOC Models

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    We introduce a model able to reproduce the main features of 1/f noise: hyper-universality (the power-law exponents are independent on the dimension of the system; we show here results in d=1,2) and apparent lack of a low-frequency cutoff in the power spectrum. Essential ingredients of this model are an activation-deactivation process and dissipation.Comment: 3 Latex pages, 2 eps Figure

    Dense transcript profiling in single cells by image correlation decoding

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    Sequential barcoded fluorescent in situ hybridization (seqFISH) allows large numbers of molecular species to be accurately detected in single cells, but multiplexing is limited by the density of barcoded objects. We present correlation FISH (corrFISH), a method to resolve dense temporal barcodes in sequential hybridization experiments. Using corrFISH, we quantified highly expressed ribosomal protein genes in single cultured cells and mouse thymus sections, revealing cell-type-specific gene expression

    Grazing incidence x ray fluorescence analysis for non destructive determination of In and Ga depth profiles in Cu In,Ga Se2 absorber films

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    Development of highly efficient thin film solar cells involves band gap engineering by tuning their elemental composition with depth. Here we show that grazing incidence X ray fluorescence GIXRF analysis using monochromatic synchrotron radiation and well characterized instrumentation is suitable for a non destructive and reference free analysis of compositional depth profiles in thin films. Variation of the incidence angle provides quantitative access to the in depth distribution of the elements, which are retrieved from measured fluorescence intensities by modeling parameterized gradients and fitting calculated to measured fluorescence intensities. Our results show that double Ga gradients in Cu In1 x,Gax Se2 can be resolved by GIXR

    Dihyperon in Chiral Colour Dielectric Model

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    The mass of dihyperon with spin, parity Jπ=0+J^{\pi}=0^{+} and isospin I=0I = 0 is calculated in the framework of Chiral colour dielectric model. The wave function of the dihyperon is expressed as a product of two colour-singlet baryon clusters. Thus the quark wave functions within the cluster are antisymmetric. Appropriate operators are then used to antisymmetrize inter-cluster quark wave functions. The radial part of the quark wavefunctions are obtained by solving the the quark and dielectric field equations of motion obtained in the Colour dielectric model. The mass of the dihyperon is computed by including the colour magnetic energy as well as the energy due to meson interaction. The recoil correction to the dihyperon mass is incorporated by Peierls-Yoccoz technique. We find that the mass of the dihyperon is smaller than the ΛΛ\Lambda-\Lambda threshold by over 100 MeV. The implications of our results on the present day relativistic heavy ion experiments is discussed.Comment: LaTeX, 13 page
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