515 research outputs found
Ultraviolet Radiation Constraints around the Circumstellar Habitable Zones
Ultraviolet radiation is known to inhibit photosynthesis, induce DNA
destruction and cause damage to a wide variety of proteins and lipids. In
particular, UV radiation between 200-300 nm becomes energetically very damaging
to most of the terrestrial biological systems. On the other hand, UV radiation
is usually considered one of the most important energy source on the primitive
Earth for the synthesis of many biochemical compounds and, therefore, essential
for several biogenesis processes. In this work, we use these properties of the
UV radiation to define the bounderies of an ultraviolet habitable zone. We also
analyze the evolution of the UV habitable zone during the main sequence stage
of the star. We apply these criteria to study the UV habitable zone for those
extrasolar planetary systems that were observed by the International
Ultraviolet Explorer (IUE). We analyze the possibility that extrasolar planets
and moons could be suitable for life, according to the UV constrains presented
in this work and other accepted criteria of habitability (liquid water, orbital
stability, etc.).Comment: 34 pages, 8 figures Accepted for publication by Icaru
Elastic fluctuations as observed in a confocal slice
Recent confocal experiments on colloidal solids motivate a fuller study of
the projection of three-dimensional fluctuations onto a two-dimensional
confocal slice. We show that the effective theory of a projected crystal
displays several exceptional features, such as non-standard exponents in the
dispersion relations. We provide analytic expressions for the effective
two-dimensional elastic properties which allow one to work back from sliced
experimental observations to three-dimensional elastic constants.Comment: 5 pages, 2 figure
Toward the reflectance measurement of micro components
Today, the controls by reflection of optical coatings are most of the time made with flat samples thanks to commercial spectrophotometers. However, components become smaller and more complex, curvature radius of lenses or mirrors are larger, so that measures are not so accurate and sometimes are not possible. Flat samples don’t represent anymore the real reflection ability of the component. So to perform this kind of measurements, special devices are needed. A new means developed by the French Atomic Energy Commission (CEA) is proposed to fill in this gap. This device has a accuracy of 0.06% on flat sample over the 400 nm to 950 nm wavelength range with a spot size of 100 mm. It can measure the reflectance of samples even if their shapes are spherical. We investigate stainless steel balls and optical micro components (mirrors and lens) thanks to the tiny size of the analyzing spot of our reflectometer. Herein we introduce our first results on small optical components and show the limiting factors of our device
Non-Newtonian behavior and molecular structure of Cooee bitumen under shear flow:A non-equilibrium molecular dynamics study
The rheology and molecular structure of a model bitumen (Cooee bitumen) under shear are investigated in the non-Newtonian regime using non-equilibrium molecular dynamics simulations. The shear viscosity, normal stress differences, and pressure of the bitumen mixture are computed at different shear rates and different temperatures. The model bitumen is shown to be a shear-thinning fluid at all temperatures. In addition, the Cooee model is able to reproduce experimental results showing the formation of nanoaggregates composed of stacks of flat aromatic molecules in bitumen. These nanoaggregates are immersed in a solvent of saturated hydrocarbon molecules. At a fixed temperature, the shear-shinning behavior is related not only to the inter- and intramolecular alignments of the solvent molecules but also to the decrease of the average size of the nanoaggregates at high shear rates. The variation of the viscosity with temperature at different shear rates is also related to the size and relative composition of the nanoaggregates. The slight anisotropy of the whole sample due to the nanoaggregates is considered and quantified. Finally, the position of bitumen mixtures in the broad literature of complex systems such as colloidal suspensions, polymer solutions, and associating polymer networks is discussed
Progress towards an accurate determination of the Boltzmann constant by Doppler spectroscopy
In this paper, we present significant progress performed on an experiment
dedicated to the determination of the Boltzmann constant, k, by accurately
measuring the Doppler absorption profile of a line in a gas of ammonia at
thermal equilibrium. This optical method based on the first principles of
statistical mechanics is an alternative to the acoustical method which has led
to the unique determination of k published by the CODATA with a relative
accuracy of 1.7 ppm. We report on the first measurement of the Boltzmann
constant by laser spectroscopy with a statistical uncertainty below 10 ppm,
more specifically 6.4 ppm. This progress results from improvements in the
detection method and in the statistical treatment of the data. In addition, we
have recorded the hyperfine structure of the probed saQ(6,3) rovibrational line
of ammonia by saturation spectroscopy and thus determine very precisely the
induced 4.36 (2) ppm broadening of the absorption linewidth. We also show that,
in our well chosen experimental conditions, saturation effects have a
negligible impact on the linewidth. Finally, we draw the route to future
developments for an absolute determination of with an accuracy of a few ppm.Comment: 22 pages, 11 figure
Cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: implications for clinical trials
International audienceABSTRACT : INTRODUCTION : Early randomized clinical trials of autologous bone marrow cardiac stem cell therapy have reported contradictory results highlighting the need for a better evaluation of protocol designs. This study was designed to quantify and compare whole body and heart cell distribution after intracoronary or peripheral intravenous injection of autologous bone marrow mononuclear cells in a porcine acute myocardial infarction model with late reperfusion. METHODS : Myocardial infarction was induced using balloon inflation in the left coronary artery in domestic pigs. At seven days post-myocardial infarction, 1 x 10(8) autologous bone marrow mononuclear cells were labeled with fluorescent marker and/or 99mTc radiotracer, and delivered using intracoronary or peripheral intravenous injection (leg vein). RESULTS : Scintigraphic analyses and Upsilon-emission radioactivity counting of harvested organs showed a significant cell fraction retained within the heart after intracoronary injection (6 +/- 1.7% of injected radioactivity at 24 hours), whereas following peripheral intravenous cell injection, no cardiac homing was observed at 24 hours and cells were mainly detected within the lungs. Importantly, no difference was observed in the percentage of retained cells within the myocardium in the presence or absence of myocardial infarction. Histological evaluation did not show arterial occlusion in both animal groups and confirmed the presence of bone marrow mononuclear cells within the injected myocardium area. CONCLUSIONS : Intravenous bone marrow mononuclear cell injection was ineffective to target myocardium. Myocardial cell distribution following intracoronary injection did not depend on myocardial infarction presence, a factor that could be useful for cardiac cell therapy in patients with chronic heart failure of non-ischemic origin or with ischemic myocardium without myocardial infarction
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