155 research outputs found
Flare energetics
In this investigation of flare energetics, researchers sought to establish a comprehensive and self-consistent picture of the sources and transport of energy within a flare. To achieve this goal, they chose five flares in 1980 that were well observed with instruments on the Solar Maximum Mission, and with other space-borne and ground-based instruments. The events were chosen to represent various types of flares. Details of the observations available for them and the corresponding physical parameters derived from these data are presented. The flares were studied from two perspectives, the impulsive and gradual phases, and then the results were compared to obtain the overall picture of the energics of these flares. The role that modeling can play in estimating the total energy of a flare when the observationally determined parameters are used as the input to a numerical model is discussed. Finally, a critique of the current understanding of flare energetics and the methods used to determine various energetics terms is outlined, and possible future directions of research in this area are suggested
Cluster coherent potential approximation for electronic structure of disordered alloys
We extend the single-site coherent potential approximation (CPA) to include
the effects of non-local disorder correlations (alloy short-range order) on the
electronic structure of random alloy systems. This is achieved by mapping the
original Anderson disorder problem to that of a selfconsistently embedded
cluster. This cluster problem is then solved using the equations of motion
technique. The CPA is recovered for cluster size , and the disorder
averaged density-of-states (DOS) is always positive definite. Various new
features, compared to those observed in CPA, and related to repeated scattering
on pairs of sites, reflecting the effect of SRO are clearly visible in the DOS.
It is explicitly shown that the cluster-CPA method always yields
positive-definite DOS. Anderson localization effects have been investigated
within this approach. In general, we find that Anderson localization sets in
before band splitting occurs, and that increasing partial order drives a
continuous transition from an Anderson insulator to an incoherent metal.Comment: 7 pages, 6 figures. submitted to PR
Nuclear Broadening Effects on Hard Prompt Photons at Relativistic Energies
We calculate prompt photon production in high-energy nuclear collisions. We
focus on the broadening of the intrinsic transverse momenta of the partons in
the initial state from nuclear effects, and their influence on the prompt
photon p_t distribution. Comparing to WA98 data from Pb+Pb collisions at SPS
energy we find evidence for the presence of nuclear broadening at high p_t in
this hard process. Below p_t=2.7 GeV the photon distribution is due to small
momentum transfer processes. At RHIC energy, the effect of intrinsic transverse
momentum on the spectrum of prompt photons is less prominent. The region
p_t=3-4 GeV would be the most promising for studying the nuclear broadening
effects at that energy. Below p_t=2-3 GeV the contribution from large momentum
transfers flattens out, and we expect that region to be dominated by soft
contributions.Comment: 19 pages, 3 figures, minor changes, a few references adde
The charged-hadron/pion ratio at the Relativistic Heavy Ion Collider
The hadron/pion ratio is calculated in 200 GeV AuAu collisions at
midrapidity, applying pQCD and non-universal transverse-momentum broadening.
Arguments are presented for such non-universality, and the idea is implemented
in a model, which explains the enhancement of the hadron/pion ratio in central
AuAu collisions. The model also describes the qualitative difference between
the recently-measured dAu nuclear enhancement factors for pions and charged
hadrons.Comment: 4 pages, 3 figure
Meson-induced correlations of nucleons in nuclear Compton scattering
The non-resonant (seagull) contribution to the nuclear Compton amplitude at
low energies is strongly influenced by nucleon correlations arising from meson
exchange. We study this problem in a modified Fermi gas model, where nuclear
correlation functions are obtained with the help of perturbation theory. The
dependence of the mesonic seagull amplitude on the nuclear radius is
investigated and the influence of a realistic nuclear density on this amplitude
is dicussed. We found that different form factors appear for the static part
(proportional to the enhancement constant ) of the mesonic seagull
amplitude and for the parts, which contain the contribution from
electromagnetic polarizabilities.Comment: 15 pages, Latex, epsf.sty, 9 eps figures
Estimates of hadron azimuthal anisotropy from multiparton interactions in proton-proton collisions at sqrt(s) = 14 TeV
We estimate the amount of collective "elliptic flow" expected at mid-rapidity
in proton-proton (p-p) collisions at the CERN Large Hadron Collider (LHC),
assuming that any possible azimuthal anisotropy of the produced hadrons with
respect to the plane of the reaction follows the same overlap-eccentricity and
particle-density scalings as found in high-energy heavy ion collisions. Using a
Glauber eikonal model, we compute the p-p eccentricities, transverse areas and
particle-multiplicities for various phenomenological parametrisations of the
proton spatial density. For realistic proton transverse profiles, we find
integrated elliptic flow v2 parameters below 3% in p-p collisions at sqrt(s) =
14 TeV.Comment: 17 pages, 9 figures. Very minor mods. Version to appear in EPJ-
Octreotide (long-acting release formulation) treatment in patients with graves' orbitopathy: clinical results of a four-month, randomized, placebo-controlled, double-blind study.
There are few effective, safe modalities for the management of Graves' ophthalmopathy (GO), a cell-mediated immune comorbidity of thyroid disease. Somatostatin analogs inhibit lymphocyte proliferation and activation, and accumulate in the orbital tissue of patients with GO. A double-blind, placebo-controlled study of a long-acting somatostatin analog [16 wk of long-acting release formulation of octreotide (octreotide-LAR)] was conducted in 51 patients with mild active GO with the aim of preventing deterioration and precluding the need for more aggressive therapeutic modalities, such as glucocorticoids or radiotherapy. No treatment effect was observed for the primary end point (a composite parameter defining the outcome as either success or failure on the basis of changes in class/grade of the severity index and Clinical Activity Scale of GO). The Clinical Activity Scale score was reduced for patients treated with octreotide-LAR, but without any significant difference with respect to patients receiving placebo. However, octreotide-LAR significantly reduced proptosis (as measured by exophthalmometry). This was associated with nonsignificant differences in favor of octreotide-LAR in a series of proptosis-related parameters: class III grade, opening of the upper eyelid, the difference in ocular pressure between primary position and upgaze, and extraocular muscle involvement. By magnetic resonance imaging evaluation the extraocular muscle volumes appeared reduced, but nonsignificantly. No significant correlation between the initial uptake of the somatostatin analog indium-labeled and the response to treatment was observed. One patient in the octreotide-LAR group developed gallstones. In this study, octreotide-LAR did not seem suitable to mitigate activity in mild GO. Surprisingly, it significantly reduced proptosis, one of the most debilitating symptoms of GO. Additional studies are warranted to define the benefit to risk ratio of the somatostatin analogs in this indication
Search for a new gauge boson in the Experiment (APEX)
We present a search at Jefferson Laboratory for new forces mediated by
sub-GeV vector bosons with weak coupling to electrons. Such a
particle can be produced in electron-nucleus fixed-target scattering and
then decay to an pair, producing a narrow resonance in the QED trident
spectrum. Using APEX test run data, we searched in the mass range 175--250 MeV,
found no evidence for an reaction, and set an upper limit of
. Our findings demonstrate that fixed-target
searches can explore a new, wide, and important range of masses and couplings
for sub-GeV forces.Comment: 5 pages, 5 figures, references adde
Prototype Tests for the CELESTE Solar Array Gamma--Ray Telescope
The CELESTE experiment will be an Atmospheric Cherenkov detector designed to
bridge the gap in energy sensitivity between current satellite and ground-based
gamma-ray telescopes, 20 to 300 GeV. We present test results made at the former
solar power plant, Themis, in the French Pyrenees. The tests confirm the
viability of using a central tower heliostat array for Cherenkov wavefront
sampling.Comment: LaTeX2e,30 pages including 14 figures, accepted for publication by
Nuclear Instruments & Methods Section
Pathogenic Mouse Hepatitis Virus or Poly(I:C) Induce IL-33 in Hepatocytes in Murine Models of Hepatitis.
International audienceThe IL-33/ST2 axis is known to be involved in liver pathologies. Although, the IL-33 levels increased in sera of viral hepatitis patients in human, the cellular sources of IL-33 in viral hepatitis remained obscure. Therefore, we aimed to investigate the expression of IL-33 in murine fulminant hepatitis induced by a Toll like receptor (TLR3) viral mimetic, poly(I:C) or by pathogenic mouse hepatitis virus (L2-MHV3). The administration of poly(I:C) plus D-galactosamine (D-GalN) in mice led to acute liver injury associated with the induction of IL-33 expression in liver sinusoidal endothelial cells (LSEC) and vascular endothelial cells (VEC), while the administration of poly(I:C) alone led to hepatocyte specific IL-33 expression in addition to vascular IL-33 expression. The hepatocyte-specific IL-33 expression was down-regulated in NK-depleted poly(I:C) treated mice suggesting a partial regulation of IL-33 by NK cells. The CD1d KO (NKT deficient) mice showed hepatoprotection against poly(I:C)-induced hepatitis in association with increased number of IL-33 expressing hepatocytes in CD1d KO mice than WT controls. These results suggest that hepatocyte-specific IL-33 expression in poly(I:C) induced liver injury was partially dependent of NK cells and with limited role of NKT cells. In parallel, the L2-MHV3 infection in mice induced fulminant hepatitis associated with up-regulated IL-33 expression as well as pro-inflammatory cytokine microenvironment in liver. The LSEC and VEC expressed inducible expression of IL-33 following L2-MHV3 infection but the hepatocyte-specific IL-33 expression was only evident between 24 to 32h of post infection. In conclusion, the alarmin cytokine IL-33 was over-expressed during fulminant hepatitis in mice with LSEC, VEC and hepatocytes as potential sources of IL-33
- …