519 research outputs found

    On the dynamic linkages between CO2 emissions, energy consumption and growth in Greece

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    This paper attempts to analyze the short-and long-run causal dynamic interactions between energy consumption, CO2 emissions and economic growth in Greece, using time-series techniques. To this end, annual data covering the period 1980-2012 are employed and tests for unit roots, the ARDL-bounds approach of cointegration, and Granger-causality based on error-correction models are applied. The results reveal strong feedback in the long-run between all the examined variables. For the shortrun, there is evidence of two-way causality in all examined pairs with only exception the direction CO2 towards GDP.peer-reviewe

    Multiple sclerosis presented as clinically isolated syndrome: the need for early diagnosis and treatment

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    Sigliti-Henrietta Pelidou, Sotirios Giannopoulos, Sotiria Tzavidi, Georgios Lagos, Athanassios P KyritsisDepartment of Neurology, University of Ioannina School of Medicine, GreeceObjective: To aid in the timely diagnosis of patients who present with clinically isolated syndrome (CIS).Patients and methods: We studied 25 patients (18 women, 7 men), originally presented in our clinic with a CIS suggestive of multiple sclerosis (MS). All patients underwent the full investigation procedure including routine tests, serology, cerebrospinal fluid (CSF) examinations, evoked potentials (EPs), and magnetic resonance imaging (MRI) of brain and cervical spinal cord. Patients were imaged at baseline, and every three months thereafter up to a year.Results: The CIS was consisted of optic neuritis in 12 cases, incomplete transverse myelitis (ITM) in 7 cases, Lhermitte sign in 2 cases, internuclear ophthalmoplegia (INO) in 2 cases, mild brainstem syndrome in 1 case, and tonic-clonic seizures in 1 case. Using the baseline and three-month scans 18/25 (72%) patients developed definite MS in one year of follow up while 7 (28%) had no further findings during this observation period. Immunomodulatory treatments were applied to all definite MS patients.Conclusion: In light of new treatments available, MRIs at 3 month intervals are helpful to obtain the definite diagnosis of MS as early as possible.Keywords: multiple sclerosis, clinically isolated syndrome, optic neuritis, transverse myeliti

    Water and protein dynamics in protein-water mixtures over wide range of composition

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    © 2012 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.[EN] Water and protein dynamics in two globular protein-water systems, water-lysozyme and water-BSA (bovine serum albumine), were studied by differential scanning calorimetry (DSC), dielectric relaxation spectroscopy (DRS) and thermally stimulated depolarization currents (TSDC) techniques. Water equilibrium sorption isotherms (ESI) measurements were also recorded at room temperature. The samples covered a wide range of composition, from practically dry solid pellets (2wt% of water) to dilute solutions (82wt% of water). Crystallization and melting events of water were studied by DSC and the amount of uncrystallized water was calculated. The evolution of dynamics with hydration level was followed for various dielectric relaxation processes, the emphasis being given to relaxation processes of polar groups on the surface of the proteins and of uncrystallized water molecules. A relationship between the formation of a conductive percolating water cluster and the saturation of the water process was found.This research has been co-financed by the European Union (European Social Fund - ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF) - Research Funding Program: Heracleitus II. Investing in knowledge society through the European Social Fund.Kyritsis, A.; Panagopoulou, A.; Pissis, P.; Sabater I Serra, R.; Gómez Ribelles, JL.; Shinyashiki, N. (2012). Water and protein dynamics in protein-water mixtures over wide range of composition. IEEE Transactions on Dielectrics and Electrical Insulation. 19(4):1239-1246. https://doi.org/10.1109/TDEI.2012.6259997S1239124619

    Gender specific association of decreased bone mineral density in patients with epilepsy

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    Objective To evaluate whether epilepsy or certain antiepileptic drugs render patients prone to develop low bone mineral density (BMD) and osteoporosis risk. Methods Thirty-eight (27 males, 11 females) consecutive adult epileptic patients receiving antiepileptic drugs (AEDs) and 71 control individuals matched for race, gender, age and body mass index (BMI) were subjected to dual energy X-ray absorptiometry (DXA). Results The mean lumbar spine and total hip BMD values were lower in the patients compared to control group (0.90±0.24g/cm2 vs 1.04±0.14g/cm2, p<0.001 and 0.92±0.14g/cm2 vs 0.99±0.13g/cm2, p=0.02, respectively). At the same skeletal sites, male patients had significantly reduced BMD compared to control males (0.90±0.21g/cm2 vs 1.03±0.15g/cm2, p=0.004 and 0.93±0.14g/cm2 vs 1.02±0.13g/cm2, p=0.009, respectively) while there was a trend but no significant differences in females. This BMD reduction was independent of AED type. Conclusion Adult epileptic, predominantly male patients have lower BMD and could be screened with densitometry for early diagnosis and prevention of osteoporosis

    Occupant Tenability in Single Family Homes: Part I—Impact of Structure Type, Fire Location and Interior Doors Prior to Fire Department Arrival

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    This paper describes an experimental investigation of the impact of structure geometry, fire location, and closed interior doors on occupant tenability in typical single family house geometries using common fuels from twenty-first century fires. Two houses were constructed inside a large fire facility; a one-story, 112 m2, 3-bedroom, 1-bathroom house with 8 total rooms, and a two-story 297 m2, 4-bedroom, 2.5-bathroom house with 12 total rooms. Seventeen experiments were conducted with varying fire locations. In all scenarios, two bedrooms had doors remaining open while the door remained closed in a third bedroom immediately adjacent to the open door bedrooms. Temperature and gas measurement at the approximate location of a crawling or crouching trapped occupant (0.9 m from the floor) were utilized with the ISO 13571 fractional effective dose (FED) methodology to characterize occupant tenability up to the point of firefighter intervention. The FED values for the fire room were higher for heat exposure than for toxic gases, while target rooms reached highest FED due to CO/CO2 exposure. The closed interior door decreased FED significantly, with the worst case scenario resulting in a 2% probability of receiving an incapacitating dose compared to the worst case scenario for an open bedroom of 93% probability of receiving an incapacitating dose. In fact, in 7 of the 17 experiments, the closed interior door resulted in a less than 0.1% chance of an occupant receiving an incapacitating dose prior to firefighter ‘intervention.’Funding was provided by U.S. Department of Homeland Security (Grant No. EMW-2010-FP-00661).Ope

    Occupant Tenability in Single Family Homes: Part II: Impact of Door Control, Vertical Ventilation and Water Application

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    This paper describes experimental investigations of fire service ventilation and suppression practices in full-scale residential structures, including a one-story, 112 m2, 3 bedroom, 1 bathroom house with 8 total rooms and a two-story 297 m2, 4 bedroom, 2.5 bathroom house with 12 total rooms. The two-story house featured a modern open floor plan, two-story great room and open foyer. Seventeen experiments were conducted varying fire location, ventilation locations, the size of ventilation openings and suppression techniques. The experimental series was designed to examine the impact of several different tactics on tenability: door control, vertical ventilation size, and exterior suppression. The results of these experiments examine potential occupant and firefighter tenability and provide knowledge the fire service can use to examine their vertical ventilation and exterior suppression standard operating procedures and training content. It was observed that door control performed better at controlling the thermal exposure to occupants than did fully opening the door. Additionally, the impact of increased vertical ventilation area was minimal, and only slightly reduced the thermal exposure to occupants in a few non-fire rooms. In the two-story structure, the non-fire rooms on the second floor consistently had larger thermal fractional effective rate (FER) values (approximately 2.59 the thermal risk to oocupants) than did the non-fire rooms on the first floor. Water application was also shown to reduce the thermal risk to occupants 60 s after water application 1/3rd the original values on second floor rooms of the two-story structure and by at least 1/5th of the original values on the first floor rooms of both structures. Data also showed that the impact of front door ventilation on the toxic gases exposure was minimal, as the toxic gases FER actually increased after front door ventilation for several experiments. However, after vertical ventilation there was a 30% reduction in the toxic gases exposure rate in two of the one-story structure experiments.Funding was provided by the Department of Homeland Security (Grant No. EMW-2010-FP-00661).Ope

    The ineffectiveness of CSR : understanding garment company commitments to living wages in global supply chains

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    In the face of pressure from civil society, unions and consumers to improve labour standards for the workers producing their goods, companies at the helm of global garment supply chains have made commitments to pay living wages within their supply chains. Harnessing insights from the critical political economy literature on corporate social responsibility (CSR), we investigate the actions of garment companies to meet these commitments. We do so through analysis of original data from a survey of 20 leading garment companies, which we co-developed in 2018-2019, as well as publicly available information for garment companies and relevant multi-stakeholder initiatives. Based on this data, we argue there is very little evidence to suggest companies have made meaningful progress towards achieving commitments to pay living wages in their supply chains, challenging widespread assumptions about CSR’s benefits to workers. We argue that in the face of mounting evidence of CSR ineffectiveness, including our own, there is a need for new political economy research into the benefits that companies derive from CSR commitments that deflect attention from their core business models and the uneven value distribution within global supply chains
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