Non-invasive thermometer based on proximity superconductor for ultra-sensitive calorimetry

We present radio-frequency thermometry based on a tunnel junction between a superconductor and proximitized normal metal. It allows operation in a wide range of biasing conditions. We demonstrate that the standard finite-bias quasiparticle tunneling thermometer suffers from large dissipation and loss of sensitivity at low temperatures, whereas thermometry based on zero bias anomaly avoids both these problems. For these reasons the latter method is suitable down to lower temperatures, here to about 25 mK. Both thermometers are shown to measure the same local temperature of the electrons in the normal metal in the range of their applicability

Nanoscale Quantum Calorimetry with Electronic Temperature Fluctuations

Motivated by the recent development of fast and ultra-sensitive thermometry in nanoscale systems, we investigate quantum calorimetric detection of individual heat pulses in the sub-meV energy range. We propose a hybrid superconducting injector-calorimeter set-up, with the energy of injected pulses carried by tunneling electrons. Treating all heat transfer events microscopically, we analyse the statistics of the calorimeter temperature fluctuations and derive conditions for an accurate measurement of the heat pulse energies. Our results pave the way for novel, fundamental quantum thermodynamics experiments, including calorimetric detection of single microwave photons.Comment: 6 pages, 3 figures plus supplemental material, 8 pages, 1 figur

Lateral and normal forces between patterned substrates induced by nematic fluctuations

We consider a nematic liquid crystal confined by two parallel flat substrates whose anchoring conditions vary periodically in one lateral direction. Within the Gaussian approximation, we study the effective forces between the patterned substrates induced by the thermal fluctuations of the nematic director. The shear force oscillates as function of the lateral shift between the patterns on the lower and the upper substrates. We compare the strength of this fluctuation-induced lateral force with the lateral van der Waals force arising from chemically structured adsorbed monolayers. The fluctuation-induced force in normal direction is either repulsive or attractive, depending on the model parameters.Comment: 9 pages, 9 figure

Quantifying Spatiotemporal Chaos in Rayleigh-B\'enard Convection

Using large-scale parallel numerical simulations we explore spatiotemporal chaos in Rayleigh-B\'enard convection in a cylindrical domain with experimentally relevant boundary conditions. We use the variation of the spectrum of Lyapunov exponents and the leading order Lyapunov vector with system parameters to quantify states of high-dimensional chaos in fluid convection. We explore the relationship between the time dynamics of the spectrum of Lyapunov exponents and the pattern dynamics. For chaotic dynamics we find that all of the Lyapunov exponents are positively correlated with the leading order Lyapunov exponent and we quantify the details of their response to the dynamics of defects. The leading order Lyapunov vector is used to identify topological features of the fluid patterns that contribute significantly to the chaotic dynamics. Our results show a transition from boundary dominated dynamics to bulk dominated dynamics as the system size is increased. The spectrum of Lyapunov exponents is used to compute the variation of the fractal dimension with system parameters to quantify how the underlying high-dimensional strange attractor accommodates a range of different chaotic dynamics

Speeding-up a quantum refrigerator via counter-diabatic driving

We study the application of a counter-diabatic driving (CD) technique to enhance the thermodynamic efficiency and power of a quantum Otto refrigerator based on a superconducting qubit coupled to two resonant circuits. Although the CD technique is originally designed to counteract non-adiabatic coherent excitations in isolated systems, we find that it also works effectively in the open system dynamics, improving the coherence-induced losses of efficiency and power. We compare the CD dynamics with its classical counterpart, and find a deviation that arises because the CD is designed to follow the energy eigenbasis of the original Hamiltonian, but the heat baths thermalize the system in a different basis. We also discuss possible experimental realizations of our model.Comment: 9 pages, 8 figure

Differentiation of definitive endoderm from human induced pluripotent stem cells on hMSCs feeder in a defined medium

Background: The Definitive Endoderm (DE) differentiation using the undefined media and non-human feeders can cause contaminations in the generated cells for therapeutic applications. Therefore, generating safer and more appropriate DE cells is needed. This study compared five different methods to establish an appropriate method for inducing an efficient DE differentiation from Human Induced Pluripotent Stem Cells (hiPSCs) on an appropriate feeder in a more defined medium. Methods: Human Induced Pluripotent Stem Cells (hiPSCs) were cultured on inactivated feeders. Passaged hiPSCs, without feeder, were incubated for three days with Activin-A and different endodermal differentiation media including 1-FBS, 2-B27, 3- ITS and albumin fraction-V, 4-B27 and ITS and 5-like the third medium. The feeder cells in the first four methods were Mouse Embryonic Fibroblasts (MEFs) and in the fifth method were human adult bone marrow Mesenchymal Stem Cells (hMSCs). DE markers FOXA2, SOX17 and CXCR4 and also pluripotency marker OCT4 were evaluated using qRT-PCR, as well as FOXA2 by the immunocytochemistry. Results: QRT-PCR analysis showed that after three days, the expression levels of DE and pluripotency markers in the differentiated hiPSCs among all five groups did not have any significant differences. Similarly, the immunocytochemistry analysis demonstrated that the differentiated hiPSCs expressed FOXA2, with no significant differences. Conclusion: Despite this similarity in the results, the third differentiation medium has more defined and cost effective components. Furthermore, hMSC, a human feeder, is safer than MEF. Therefore, the fifth method is preferable among other DE differentiation methods and can serve as a fundamental method helping the development of regenerative medicine. © 2016, Avicenna Journal of Medical Biotechnology. All rights reserved

Quantum trajectory analysis of single microwave photon detection by nanocalorimetry

We apply quantum trajectory techniques to analyze a realistic set-up of a superconducting qubit coupled to a heat bath formed by a resistor, a system that yields explicit expressions of the relevant transition rates to be used in the analysis. We discuss the main characteristics of the jump trajectories and relate them to the expected outcomes ("clicks") of a fluorescence measurement using the resistor as a nanocalorimeter. As the main practical outcome we present a model that predicts the time-domain response of a realistic calorimeter subject to single microwave photons, incorporating the intrinsic noise due to the fundamental thermal fluctuations of the absorber and finite bandwidth of a thermometer

Ultrasensitive Calorimetric Detection of Single Photons from Qubit Decay

We describe a qubit linearly coupled to a heat bath, either directly or via a cavity. The main focus of the paper is on calorimetric detection in a realistic circuit, specifically a solid-state qubit coupled to a resistor as an absorber. The bath in the model is formed of oscillators initially in the ground state with a distribution of energies and coupling strengths. A direct numerical solution of the Schrodinger equation for the full system including up to 106 oscillators in the bath verifies the expected decay process. We address quantitatively the question of separation of the qubit and bath by adding a cavity in between which by detuning allows one to adjust the decay rate into a convenient regime for detection purposes. Most importantly, we propose splitting a quantum to two uncoupled baths and performing a cross-correlation measurement of their temperatures. This technique enhances significantly the signal-to-noise ratio of the calorimeter.Peer reviewe