Flat conductor cable commercialization project

An undercarpet flat conductor cable and a baseboard flat conductor cable system were studied for commercialization. The undercarpet system is designed for use in office and commercial buildings. It employs a flat power cable, protected by a grounded metal shield, that terminates in receptacles mounted on the floor. It is designed to interface with a flat conductor cable telephone system. The baseboard system consists of a flat power cable mounted in a plastic raceway; both the raceway and the receptacles are mounted on the surface of the baseboard. It is designed primarily for use in residential buildings, particularly for renovation and concrete and masonry construction

Suing Foreign Officials in U.S. Courts: Upholding Separation of Powers by Limiting Judicial Abrogation of Immunity

This Note will propose the constitutional framework courts should implement when suits are brought against individual foreign officials post-Samantar, specifically arguing that the constitutional allocation of foreign affairs powers requires U.S. courts to broadly insulate foreign officials from suit absent authorization from a political branch. Part I examines the law of nations and its incorporation into the specific foreign relations powers delegated by the Constitution to the political branches, highlighting that the power to affect relations with foreign sovereigns resides in the political branches. Part II explains the Supreme Court’s development of foreign sovereign immunity and the act of state doctrine—which were both informed by the law of nations—leading up to its decision in Samantar. Part III analyzes Samantar after remand, with particular emphasis on the Fourth Circuit’s judicially created abrogation of immunity for foreign officials when plaintiffs allege violations of jus cogens norms of international law. This Part also describes the considerable problems, particularly constitutionally but also pragmatically, with recognition of a judicially created jus cogens exception to immunity. Part IV proposes the constitutional framework under which analysis of a foreign official’s amenability to suit should proceed. Specifically, this Note argues that the Constitution itself requires U.S. courts to abstain from entering a judgment against current and former officials of recognized foreign sovereigns, absent express authorization from a political branch. Therefore, the Fourth Circuit’s judicially created abrogation of immunity for allegations of jus cogens violations runs afoul of the separation of powers because it usurps the constitutionally delegated powers of the political branches to shape U.S. foreign relations. Courts should first employ two separate immunity doctrines in suits involving foreign officials: status-based immunity, which bars suits against sitting heads of state and foreign officials, and conduct-based immunity, which bars suits for acts committed by officials in their official capacities. Finally, when suit is brought against an individual who was or is an official of a recognized sovereign for acts committed in his official capacity and within his sovereign territory, U.S. courts should invoke the act of state doctrine to dismiss the suit because it is impermissible for American courts to “sit in judgment on the acts of the government of another, done within its own territory,” absent express authorization from a political branch. By refraining from entering judgment in suits against foreign officials, U.S. courts uphold the constitutional allocation of foreign affairs powers to the political branches

Suing Foreign Officials in U.S. Courts: Upholding Separation of Powers by Limiting Judicial Abrogation of Immunity

This Note will propose the constitutional framework courts should implement when suits are brought against individual foreign officials post-Samantar, specifically arguing that the constitutional allocation of foreign affairs powers requires U.S. courts to broadly insulate foreign officials from suit absent authorization from a political branch. Part I examines the law of nations and its incorporation into the specific foreign relations powers delegated by the Constitution to the political branches, highlighting that the power to affect relations with foreign sovereigns resides in the political branches. Part II explains the Supreme Court’s development of foreign sovereign immunity and the act of state doctrine—which were both informed by the law of nations—leading up to its decision in Samantar. Part III analyzes Samantar after remand, with particular emphasis on the Fourth Circuit’s judicially created abrogation of immunity for foreign officials when plaintiffs allege violations of jus cogens norms of international law. This Part also describes the considerable problems, particularly constitutionally but also pragmatically, with recognition of a judicially created jus cogens exception to immunity. Part IV proposes the constitutional framework under which analysis of a foreign official’s amenability to suit should proceed. Specifically, this Note argues that the Constitution itself requires U.S. courts to abstain from entering a judgment against current and former officials of recognized foreign sovereigns, absent express authorization from a political branch. Therefore, the Fourth Circuit’s judicially created abrogation of immunity for allegations of jus cogens violations runs afoul of the separation of powers because it usurps the constitutionally delegated powers of the political branches to shape U.S. foreign relations. Courts should first employ two separate immunity doctrines in suits involving foreign officials: status-based immunity, which bars suits against sitting heads of state and foreign officials, and conduct-based immunity, which bars suits for acts committed by officials in their official capacities. Finally, when suit is brought against an individual who was or is an official of a recognized sovereign for acts committed in his official capacity and within his sovereign territory, U.S. courts should invoke the act of state doctrine to dismiss the suit because it is impermissible for American courts to “sit in judgment on the acts of the government of another, done within its own territory,” absent express authorization from a political branch. By refraining from entering judgment in suits against foreign officials, U.S. courts uphold the constitutional allocation of foreign affairs powers to the political branches

Urban construction and safety project

Technology utilization projects in the area of urban construction and safety included the following: development of undercarpet and baseboard flat conductor cables, flood insurance studies, tornado safety engineering, the Project TECH house at the Langley Research Center, assistance to the City of Atlanta in their environmental habitability and resource allocation program, and market assessment of a solid state diesel engine controller. The flat conductor cable and the flood insurance studies are given particular attention

Wearable device to assist independent living.

Older people increasingly want to remain living independently in their own homes. The aim of the ENABLE project is to develop a wearable device that can be used both within and outside of the home to support older people in their daily lives and which can monitor their health status, detect potential problems, provide activity reminders and offer communication and alarm services. In order to determine the specifications and functionality required for development of the device user surveys and focus groups were undertaken and use case analysis and scenario modeling carried out. The project has resulted in the development of a wrist worn device and mobile phone combination that can support and assist older and vulnerable wearers with a range of activities and services both inside and outside of their homes. The device is currently undergoing pilot trials in five European countries. The aim of this paper is to describe the ENABLE device, its features and services, and the infrastructure within which it operates

Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is characterized by muscle degeneration and progressive weakness. There is considerable inter-patient variability in disease onset and progression, which can confound the results of clinical trials. Here we show that a common null polymorphism (R577X) in ACTN3 results in significantly reduced muscle strength and a longer 10\u2009m walk test time in young, ambulant patients with DMD; both of which are primary outcome measures in clinical trials. We have developed a double knockout mouse model, which also shows reduced muscle strength, but is protected from stretch-induced eccentric damage with age. This suggests that \u3b1-actinin-3 deficiency reduces muscle performance at baseline, but ameliorates the progression of dystrophic pathology. Mechanistically, we show that \u3b1-actinin-3 deficiency triggers an increase in oxidative muscle metabolism through activation of calcineurin, which likely confers the protective effect. Our studies suggest that ACTN3 R577X genotype is a modifier of clinical phenotype in DMD patients

A market in the making: the past, present and future of direct-to-consumer genomics

It is just over two decades since a small start-up firm called University Diagnostics launched a mail-order genetic testing service in the UK in 1996. That same year, the US-based Genetics and IVF Institute began marketing its BRCA tests for breast and ovarian cancer directly to consumers via newspaper ads. Two years later, Myriad Genetics (by then the sole provider of BRCA testing in the USA) launched a consumer advertising campaign that encompassed TV, radio and popular magazines (Parthasarathy 2007). By 2001, when UK nutrigenetics firm Sciona began marketing to consumers via its website, a new trend was emerging: the growth of the direct-to-consumer genetic testing (DTCGT) market was now interlinked with the increasing use of the internet as a medium for retail shopping. Genetics was beginning to move out of the clinic and into the marketplace