1,132 research outputs found
Protection and maintenance of permanent pastures
peer reviewedAll farmers receiving direct payments are subject to compulsory cross-compliance which includes standards related to the maintenance and protection of permanent pastures. Questionnaire techniques and spatio-temporal analyses demonstrated that the ratio of permanent pasture area to agricultural land provides a simple tool for monitoring and controlling the protection of permanent pastures at the regional to Member State level. Huge variations in the ratio across Europe were related to the importance of permanent pastures, the interpretation of definitions, sources of information used, differences in calculation, and the presence of protective and/or sensitive zones.
Precautionary or complementary measures are in place in most Member States in order to prevent decreases in the ratio. The implementation of GAEC standards related to permanent pastures overlaps with the standard management requirements, national legislation and current agri-environmental programmes. The study advocates the establishment of a comprehensive geo-information platform consisting of a topologically correct inventory of all permanent pasture parcels in a 1:1 geo-referenced relation between IACS and LPIS; ancillary spatially explicit data such as orthophotos, remote sensing images and other thematic geo-databases; and, geodatabases with parcel information compiled for other monitoring purposes such as those within the framework of the Nitrates Directive or 2nd pillar support
<i>Cocconeis molesta</i> Kütz., <i>C. diaphana</i> W.Sm. and <i>C. dirupta</i> W.Greg. (Bacillariophyta): type material, ambiguities and possible synonymies
F.T. Kützing introduced Cocconeis molesta with only an uninformative description and a poor illustration: C. molesta has small, oblong valves and is an epiphyte. Another species, Cocconeis diaphana, described by William Smith, is said to have larger valves than C. molesta, with frustules that are relatively oblong. Smith described two forms: one with a distinct fascia on its raphe valve (var. β), the other without this feature. A third species, Cocconeis dirupta was described by Gregory, who expressed doubts that it differed from C. diaphana. Finally, Cocconeis molesta var. crucifera Grunow was first introduced in Van Heurck’s Atlas but was subsequently treated by Van Heurck as a synonym of C. molesta. No previous account has examined the type material of these species. In this paper, we undertake that task and examine type slides and raw material in order to discriminate these different taxa. We conclude by recognizing three species: Cocconeis molesta Kütz., C. diaphana W.Sm. and C. dirupta W.Greg. Cocconeis diaphana var. β is considered to be a synonym of C. dirupta and C. molesta var. crucifera is considered to be a synonym of C. molesta. Lectotypes are designated for C. diaphana and C. dirupta
Status of the light ion source developments at CEA/Saclay
ACC NIMInternational audienceSILHI (High Intensity Light Ion Source) is an ECR ion source producing high intensity proton ordeuteron beams at 95 keV. It is now installed in the IPHI site building, on the CEA/Saclay center. IPHI is a frontend demonstrator of high power accelerator. The source regularly delivers more than 130 mA protons in CWmode and already produced more than 170 mA deuterons in pulsed mode at nominal energy. The last beamcharacterisations, including emittance measurements, space charge compensation analysis and diagnosticimprovements, will be reported. Taking into account the SILHI experience, new developments are in progress tobuild and test a 5 mA deuteron source working in CW mode. This new source will also operate at 2.45 GHz andpermanent magnets will provide the magnetic configuration. This source, of which the design will be discussed,will have to fit in with the SPIRAL 2 accelerator developed at GANIL to produce Radioactive Ion Beams. TheH- test stand status is briefly presented here and detailed in companion papers.This work is partly supported by the European Commission under contract n°: HPRI-CT-2001-50021
Disorder-Driven Pretransitional Tweed in Martensitic Transformations
Defying the conventional wisdom regarding first--order transitions, {\it
solid--solid displacive transformations} are often accompanied by pronounced
pretransitional phenomena. Generally, these phenomena are indicative of some
mesoscopic lattice deformation that ``anticipates'' the upcoming phase
transition. Among these precursive effects is the observation of the so-called
``tweed'' pattern in transmission electron microscopy in a wide variety of
materials. We have investigated the tweed deformation in a two dimensional
model system, and found that it arises because the compositional disorder
intrinsic to any alloy conspires with the natural geometric constraints of the
lattice to produce a frustrated, glassy phase. The predicted phase diagram and
glassy behavior have been verified by numerical simulations, and diffraction
patterns of simulated systems are found to compare well with experimental data.
Analytically comparing to alternative models of strain-disorder coupling, we
show that the present model best accounts for experimental observations.Comment: 43 pages in TeX, plus figures. Most figures supplied separately in
uuencoded format. Three other figures available via anonymous ftp
Effects of ocean acidification on invertebrate settlement at volcanic CO<inf>2</inf> vents
We present the first study of the effects of ocean acidification on settlement of benthic invertebrates and microfauna. Artificial collectors were placed for 1 month along pH gradients at CO2 vents off Ischia (Tyrrhenian Sea, Italy). Seventy-nine taxa were identified from six main taxonomic groups (foraminiferans, nematodes, polychaetes, molluscs, crustaceans and chaetognaths). Calcareous foraminiferans, serpulid polychaetes, gastropods and bivalves showed highly significant reductions in recruitment to the collectors as pCO2 rose from normal (336-341 ppm, pH 8.09-8.15) to high levels (886-5,148 ppm) causing acidified conditions near the vents (pH 7.08-7.79). Only the syllid polychaete Syllis prolifera had higher abundances at the most acidified station, although a wide range of polychaetes and small crustaceans was able to settle and survive under these conditions. A few taxa (Amphiglena mediterranea, Leptochelia dubia, Caprella acanthifera) were particularly abundant at stations acidified by intermediate amounts of CO2 (pH 7. 41-7.99). These results show that increased levels of CO2 can profoundly affect the settlement of a wide range of benthic organisms. © 2010 Springer-Verlag
Source identification and distribution reveals the potential of the geochemical Antarctic sea ice proxy IPSO25
The presence of a di-unsaturated highly branched isoprenoid (HBI) lipid biomarker (diene II) in Southern Ocean sediments has previously been proposed as a proxy measure of palaeo Antarctic sea ice. Here we show that a source of diene II is the sympagic diatom Berkeleya adeliensis Medlin. Furthermore, the propensity for B. adeliensis to flourish in platelet ice is reflected by an offshore downward gradient in diene II concentration in >100 surface sediments from Antarctic coastal and near-coastal environments. Since platelet ice formation is strongly associated with super-cooled freshwater inflow, we further hypothesize that sedimentary diene II provides a potentially sensitive proxy indicator of landfast sea ice influenced by meltwater discharge from nearby glaciers and ice shelves, and re-examination of some previous diene II downcore records supports this hypothesis. The term IPSO25-Ice Proxy for the Southern Ocean with 25 carbon atoms-is proposed as a proxy name for diene II
Drugs in early clinical development for the treatment of osteosarcoma
Introduction: Osteosarcomas are the main malignant primary bone tumours found in children
and young adults. Conventional treatment is based on diagnosis and resection surgery,
combined with polychemotherapy. This is a protocol that was established in the 1970s.
Unfortunately, this therapeutic approach has reached a plateau of efficacy and the patient
survival rate has not improved in the last four decades. New therapeutic approaches are thus
required to improve the prognosis for osteosarcoma patients.
Areas covered: From the databases available and published scientific literature, the present
review gives an overview of the drugs currently in early clinical development for the
treatment of osteosarcoma. For each drug, a short description is given of the relevant
scientific data supporting its development.
Expert opinion: Multidrug targeted approaches are set to emerge, given the heterogeneity of
osteosarcoma subtypes and the multitude of therapeutic responses. The key role played by the
microenvironment in the disease increases the number of therapeutic targets (such as
macrophages or osteoclasts), as well as the master proteins that control cell proliferation or
cell death. Ongoing phase I/II trials are important steps, not only for identifying new therapies
with greater safety and efficacy, but also for better defining the role played by the
microenvironment in the pathogenesis of osteosarcoma
In situ measurement of bovine serum albumin interaction with gold nanospheres
Here we present in situ observations of adsorption of bovine serum albumin (BSA) on citratestabilized
gold nanospheres. We implemented scattering correlation spectroscopy as a tool to
quantify changes in the nanoparticle Brownian motion resulting from BSA adsorption onto the
nanoparticle surface. Protein binding was observed as an increase in the nanoparticle
hydrodynamic radius. Our results indicate the formation of a protein monolayer at similar albumin
concentrations as those found in human blood. Additionally, by monitoring the frequency and
intensity of individual scattering events caused by single gold nanoparticles passing the
observation volume, we found that BSA did not induce colloidal aggregation, a relevant result
from the toxicological viewpoint. Moreover, to elucidate the thermodynamics of the gold
nanoparticle-BSA association, we measured an adsorption isotherm which was best described by
an anti-cooperative binding model. The number of binding sites based on this model was
consistent with a BSA monolayer in its native state. In contrast, experiments using poly-ethylene
glycol capped gold nanoparticles revealed no evidence for adsorption of BSA
Tourisme
Si, selon Galilée, l\u27univers est un livre écrit par Dieu en caractères mathématiques, la ou les mondialisation(s) sont un univers laborieusement écrit par les hommes en histoires complexes et à des fins qu\u27ils ne maîtrisent guère !
Confusion, complexité, effets cachés, voire pervers... voilà qui autorise toutes les thèses, toutes les extrapolations - et qui donne a contrario toute sa valeur à ce travail dictionnairique d\u27approche fine et pondérée des points les plus significatifs de cet ensemble de phénomènes qui bouleversent la planète.
Thèmes généraux ("agriculture", "pauvreté") ou réalités spécifiques ("bourse", "libre circulation des personnes", "médias"), vocabulaire dédié ("glocal", "fracture numérique", "métropolisation") ou réflexif ("temps du monde", "universalisme"), l\u27utilisateur de cet ouvrage est convié à un vaste parcours où le sens se construit à la lecture des entrées et dans le jeu des renvois.
De courts essais d\u27auteur affrontent le débat et développent des points de vue plus personnels : "Développement durable, slogan ou voie d\u27avenir ?", "France, de l\u27avant-poste à l\u27arrière-garde ?", "Une gouvernance mondiale est-elle concevable ?"), etc.
Au total, une source d\u27information et un outil de réflexion incomparables sur les grands thèmes contemporains : dynamique des réseaux transnationaux, liens virtuel / réel, remodelage de la souveraineté étatique, "clash" des civilisations, responsabilité de l\u27Occident, gouvernance à l\u27échelle mondiale, péril écologique, etc.
Cet ouvrage, né de la concertation de géographes, politologues, sociologues, historiens, économistes et autres, sera pour chacun, étudiant, professionnel, lecteur cultivé, un véritable viatique pour l\u27exploration des nouveaux territoires de la pensée et de l\u27action humaines
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