Alien Registration- Sandstrom, Dora P. (New Sweden, Aroostook County)

https://digitalmaine.com/alien_docs/34404/thumbnail.jp

Alien Registration- Gardiner, Dora P. (Portland, Cumberland County)

https://digitalmaine.com/alien_docs/24120/thumbnail.jp

Chemical composition and anti-diabetic properties of Cytisus multiflorus

Bakground and aims: The interest on plants with potential medicinal properties has been increasing worldwide. In the Iberian Peninsula there are some endemic species known by the population for their pharmacologic activity with valorization potential that have not been yet characterized. The white Spanish broom (Cytisus multiflorus) is described as having anti-diabetic effect [1] and in a preliminary the hypoglycemic and hyper-insulinemic effect of an aqueous extract has been shown [2]. The aim of this work was to fractionate and analyse the composition of the aqueous extract of C. multiflorus flowering parts and evaluate its potential as an anti-diabetic agent. Materials and methods: The aqueous extract was primarily fractionated by SPE using water:methanol (W:Me) eluent (a 10% step-wise gradient W:Me from 100:0 to 0:100) followed by high performance liquid chromatography with diode array detector (HPLC-DAD). The most relevant fraction were analysed by LC-MS to determine the chemical composition. Total fenol content was determined by a modified Folin-Ciocalteau method and the anti-oxidant activity was evaluated by the DPPH mehod. Finally, the hipoglicemic potential was evaluated in vivo using glucose intolerant rats (GIR). Results: Eleven fractions of the bulk extract were obtained. Seven of these fractions (10, 30, 40, 50, 60, 70 e 80% Me) were found to have a relevant compounds, mostly flavonoid compounds, namely, rutin (50, 60 and 70% Me fractions), ferrulic acid (30% Me), referred as having hypoglicemic effect. The fractions obtained with 50 and 70% Me showed the highest content in phenol equivalents and the highest anti-oxidant effect were found in the 50 and 60% Me fractions. The 30 and 60% Me fraction had no effect on the post-prandial glicemia. Conclusions: The 30, 50, 60 and 70% Me fractions, due to their chemical composition and anti-oxidant effects were the most promising to have anti-diabetic effect. However, the 30 and 60% Me were found to be ineffective. The 50% Me fraction showed both a high content of flavonoid compounds and the highest anti-oxidant power which suggest that it may constitute the most promising one. The anti-diabetic properties of this fraction should be investigated. [1] Camejo-Rodrigues J. et al. (2003). J. Ethnopharmacol, 89, 199-209 [2] Célia M. Antunes, Laurinda R. Areias, Inês P. Vieira, Ana C. Costa, M. Teresa Tinoco, & Júlio Cruz-Morais (2009). Rev. Fitoterapia 9 (Supl.1): 91

Patient Safety Culture in Portuguese Primary

Introduction: According to the European Commission more than 37 million Primary Healthcare (PHC) users suffer Adverse Events (AE). When we talk about these unintentional and undesirable events, most of the time we are dealing with acts committed by competent and dedicated professionals, who often work in disorganized systems, and who are not very oriented towards patient safety and health care professional safety. The adoption of a safety culture is a proven useful tool to make AE less likely to occur and to minimize its consequences when these inevitably take place. Methods: The authors describe some pertinent issues that have made the evaluation of AE and Patient Safety Culture (PSC) in Portuguese PHC particularly challenging and describe the preliminary results of a project for the assessment of PSC using the Medical Office Survey on Patient Safety Culture (MOSOPSC). This instrument has been translated, adapted and validated by the authors for the study population. Results: Studies about AE in PHC are scarce, but admittedly necessary. Despite the socio-economic instability experienced in Portugal, the preliminary results obtained by the authors promise a proactive PSC with dedicated health professionals, working as a team and recognizing the problem of adverse events in PHC of the Madeira Island. Discussion: The concepts and methodologies used in other studies cannot simply be applied to specific populations. On the Madeira Island (one autonomous region of Portugal), the issue of patient safety (PS) is difficult to approach but, nevertheless, with information and discussion it was possible to measure the PSC in PHC. Conclusion: After some adjustments, the MOSOPSC questionnaire, in addition to assessing safety culture, has helped to initiate the dialogue and discussion on the issue of PS among the various professionals. This approach has allowed these professionals to anticipate and prevent the occurrence of AE and, whenever such is not possible, notify, discuss, share and learn from those same events.info:eu-repo/semantics/publishedVersio

Orbital quantization in the high magnetic field state of a charge-density-wave system

A superposition of the Pauli and orbital coupling of a high magnetic field to charge carriers in a charge-density-wave (CDW) system is proposed to give rise to transitions between subphases with quantized values of the CDW wavevector. By contrast to the purely orbital field-induced density-wave effects which require a strongly imperfect nesting of the Fermi surface, the new transitions can occur even if the Fermi surface is well nested at zero field. We suggest that such transitions are observed in the organic metal $\alpha$-(BEDT-TTF)$_2$KHg(SCN)$_4$ under a strongly tilted magnetic field.Comment: 14 pages including 4 figure

Adolescent substance use and peer use: a multilevel analysis of cross-sectional population data

Background: Limited evidence exists concerning the importance of social contexts in adolescent substance use prevention. In addition to the important role schools play in educating young people, they are important ecological platforms for adolescent health, development and behaviors. In this light, school community contexts represent an important, but largely neglected, area of research in adolescent substance use and prevention, particularly with regard to peer influences. This study sought to add to a growing body of literature into peer contexts by testing a model of peer substance use simultaneously on individual and school community levels while taking account of several well established individual level factors. Method: We analyzed population-based data from the 2009 Youth in Iceland school survey, with 7,084 participants (response rate of 83.5%) nested within 140 schools across Iceland. Multilevel logistic regression models were used to analyze the data. Results: School-level peer smoking and drunkenness were positively related to adolescent daily smoking and lifetime drunkenness after taking account of individual level peer smoking and drunkenness. These relationships held true for all respondents, irrespective of socio-economic status and other background variables, time spent with parents, academic performance, self-assessed peer respect for smoking and alcohol use, or if they have substance-using friends or not. On the other hand, the same relationships were not found with regard to individual and peer cannabis use. Conclusions: The school-level findings in this study represent context effects that are over and above individual-level associations. This holds although we accounted for a large number of individual level variables that studies generally have not included. For the purpose of prevention, school communities should be targeted as a whole in substance use prevention programs in addition to reaching to individuals of particular concern

Exploring The Relationship Between Gratitude And Economic Perceptions

This study explores the associations between consumer gratitude and perceptions of consumer confidence and economic welfare. From a random stratified sample of adults living in the southeastern U.S., the findings reveal that a grateful outlook is positively associated with favorable perceptions of the U.S. economy, state economy, future job growth, and future income earned. Additionally, the results indicate significant differences between grateful and ungrateful individuals in terms of their perceptions of the U.S. economy, job growth, and anticipated income for the upcoming year. The results suggest that managers may want to focus on developing strong relationships with grateful customers, given that grateful customers may help firms survive tough economic times

Modelação da Distribuição Espacial Potencial do Elefante Africano (Loxodonta africana, Blumenbach) na Reserva Especial de Maputo, Moçambique

V Conferência Nacional de Cartografia e Geodesia, Centro de Congressos do Laboratório Nacional de Engenharia Civil, Lisboa, Portugal, 19 a 20 de Abril de 2007.Nesta comunicação apresenta-se uma abordagem ao problema da modelação da distribuição espacial de espécies selvagens, aplicada ao caso específico do elefante africano. O objectivo é obter empiricamente um mapa da distribuição potencial do Elefante africano na Reserva Especial de Maputo (REM); integrando para esse fim métodos estatísticos e modelação geográfica. A referida distribuição é analisada tendo em conta as duas estações tipicamente influentes nos padrões comportamentais dos elefantes na REM (i. é. Inverno Vs. Verão). A avaliação dos modelos foi feita recorrendo à área sob as curvas ROC. Visto que o grau de incerteza associado á sua produção é múltiplo, e que a capacidade de calibração dos mesmos não se revelou melhor que a hipótese nula (ou seja, não haverá diferença entre os valores observados e os estimados pelo modelo). Verifica-se que, ambos os modelos classificam adequadamente os locais (habitats) que devem ser prioritários do ponto de vista da gestão e conservação, tendo como base de arbitragem o valor sob a curva ROC, indicativo da fiabilidade dos valores probabilísticos obtidos. Para ambos os modelos esses valores consideram-se “excelentes”: 0.863 (IC95%: 0.822 – 0.904) e 0.830 (IC95%: 0.781 - 0.878), respectivamente para o modelo de Verão e Inverno