Molecular detection of parasites (Trematoda, Digenea: Bucephalidae and Monorchiidae) in the European flat oyster Ostrea edulis (Mollusca: Bivalvia)

Members of the globally distributed bivalve family Ostreidae (oysters) have a significant role in marine ecosystems and include species of high economic importance. In this work, we report the occurrence of digenean parasites of the families Bucephalidae (Prosorhynchoides sp.) and Monorchiidae (Postmonorchis sp.) in Mediterranean native populations of Ostrea edulis (but not in the introduced Magallana gigas). Molecular detection was based on DNA sequencing of the ribosomal intergenic spacer 2 (ITS2) marker. The importance of detecting the presence of overlooked digenean parasites in Mediterranean oysters is discussed. © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

Hepatotoxicity induced by greater celandine (Chelidonium majus L.): a review of the literature

The available literature assessing Chelidonium majus L. (CM) hepatotoxicity potential, and its risk to benefit assessment has been reviewed in this paper. Identification of significant scientific literature was performed via the following research databases: Cochrane Central, Google Scholar, EMBASE, Medline, Science Direct, Scopus, Web of Science, using the following keywords: "Chelidonium majus", "greater celandine", "Hepatotoxicity", "Liver" "Injury", "Toxicity" individually investigated and then again in association. CM named also greater celandine, swallow-wort, or bai-qu-cai (Chinese), has been used for a long time in traditional Chinese medicine and phytotherapy. Its extracts have been claimed to display a wide variety of biological activities: antimicrobial, anti-inflammatory, spasmolytic, antineoplastic, hepatoprotective, and analgesic. Moreover, herbal medicine suggests this plant have numerous additional effects which have not yet been scientifically evaluated, such as antitussive, diuretic, and eye-regenerative. However, despite its claimed hepatoprotective effects, several hepatotoxicity cases have been reported to be probably or highly probably connected with CM exposure, after their evaluation through liver-targeted causality assessment methods. CM hepatotoxicity has been defined as a distinct form of herb-induced liver injury (HILI), due to an idiosyncratic reaction of the metabolic type. This evidence has to be considered in relationship with the absence of considerable benefits of CM therapy. Therefore, the risk to benefit ratio of the use of herbal products containing greater celandine can actually be considered as negative

Assessment of ground-motion amplification in the Fucino Basin (Central Italy) through seismic data

The Fucino basin (Central Italy) is one of the largest intermountain alluvial plain in the Appennines range. It has a tectonic origin related to the presence of important systems of faults located in its northern and eastern edges. Some of these faults are still active and capable of generating strong seismic events as the January 13th 1915 Ms 7.0 Avezzano earthquake (about 30000 casualties). Site effects related to the soft soils filling the basin can be very important also taking into account the presence of historical villages located at the edges of the basin and new settlements developed in the area. In this paper we show the preliminary results of a seismic network installed in the Fucino area in order to collect information about site amplification effects and geometry of the basin. A lake occupied the Fucino basin for many thousands of years and it was completely drained at the end of the 19th century. We analyze ambient seismic vibrations and recordings of about 150 local earthquakes mainly related to the seismic sequence of the April 6th 2009 Mw 6.3 L’Aquila event. Moreover the strongest events of L’Aquila sequence were analyzed at the three strong-motion permanent stations operating in the area. Using standard spectral techniques we investigate the variation of resonance frequencies within the basin. The ground motion recorded in the Fucino plain is mainly characterized by strong energy at low-frequencies (f < 1 Hz) affecting both horizontal and vertical components. This is particularly evident for stations deployed in correspondence of very thick deposits of sedimentary filling, where a significant increase of ground-motion amplitude and duration is caused by locally generated surface waves. The amplification at low-frequencies (< 1 Hz) on the horizontal components can reach up a factor of 10 in comparison to nearby stiff sites. However, we found evidences of seismic amplification phenomena also for stiff sites surrounding the basin, including stations of the Italian strong motion network. The independent geological information, the shallow shear-velocity profiles available for the basin can be combined with resonance frequencies of the sites for deriving representative geological sections to be used as base for future numerical 2D-3D modeling of the seismic wave propagation in the basin. Seismic modeling can be important to reduce the seismic hazard in the area

Performance of the diamond active target prototype for the PADME experiment at the DAΦ\PhiNE BTF

The PADME experiment at the DA$\Phi$NE Beam-Test Facility (BTF) is designed to search for the gauge boson of a new $\rm U(1)$ interaction in the process e$^+$e$^-\rightarrow\gamma$+$\rm A'$, using the intense positron beam hitting a light target. The $\rm A'$, usually referred as dark photon, is assumed to decay into invisible particles of a secluded sector and it can be observed by searching for an anomalous peak in the spectrum of the missing mass measured in events with a single photon in the final state. The measurement requires the determination of the 4-momentum of the recoil photon, performed by a homogeneous, highly segmented BGO crystals calorimeter. A significant improvement of the missing mass resolution is possible using an active target capable to determine the average position of the positron bunch with a resolution of less than 1 mm. This report presents the performance of a real size $\rm (2x2 cm^2)$ PADME active target made of a thin (50 $\mu$m) diamond sensor, with graphitic strips produced via laser irradiation on both sides. The measurements are based on data collected in a beam test at the BTF in November 2015.Comment: 7 pages, 10 figure

Semantic Web Technologies Meet BIM for Accessing and Understanding Cultural Heritage

Within the EU funded project INCEPTION – Inclusive Cultural Heritage in Europe through 3D semantic modelling, the key-targeted achievement is the development of a specific cloud based platform, in order to accomplish the main objectives of accessing, understanding and strengthening European Cultural Heritage by means of enriched 3D models. The whole INCEPTION project is based on the close connection between state-of-the-art architectural modeling technologies (BIM, Building Information Modeling) and the latest cutting-edge web technologies. The platform is grounded on semantic web technologies and makes extensive use of WebGL and RESTful APIs, in order to enrich heritage 3D models by using Semantic Web standards. The INCEPTION platform will be a space for interchange of information and for the dialogue among professionals, students, scholars, curators, non-expert users, etc. Furthermore, the Semantic Web structure interlinks the platform with external Cultural Heritage available linked data and makes it gradually enhanced by specific flexible data structures provided as project specific ontologies. The paper will describe solutions based on the match between BIM, Cloud and Semantic Web

A tough egg to crack: recreational boats as vectors for invasive goby eggs and transdisciplinary management approaches

Non-native invasive species are a major threat to biodiversity, especially in freshwater ecosystems. Freshwater ecosystems are naturally rather isolated from one another. Nonetheless, invasive species often spread rapidly across water sheds. This spread is to a large extent realized by human activities that provide vectors. For example, recreational boats can carry invasive species propagules as ‘aquatic hitch-hikers’ within and across water sheds. We used invasive gobies in Switzerland as a case study to test the plausibility that recreational boats can serve as vectors for invasive fish and that fish eggs can serve as propagules. We found that the peak season of boat movements across Switzerland and the goby spawning season overlap temporally. It is thus plausible that goby eggs attached to boats, anchors or gear may be transported across watersheds. In experimental trials we found that goby eggs show resistance to physical removal (90mN attachment strength of individual eggs) and stay attached if exposed to rapid water flow (2.8m s-138 for 1h). When exposing the eggs to air, we found that hatching success remained high (&gt;95%) even after eggs had been out of water for up to 24h. It is thus plausible that eggs survive during pick up, within water and overland transport by boats. We complemented the experimental plausibility tests with a survey on how decision makers from inside and outside academia rate the feasibility of managing recreational boats as vectors. We found consensus that an installation of a preventive boat vector management is considered an effective and urgent measure. This study advances our understanding of the potential of recreational boats to serve as vectors for invasive vertebrate species, and demonstrates that preventive management of recreational boats is considered feasible by relevant decision makers in- and outside academia

SAFE: a Self Adaptive Frame Enhancer FPGA-based IP-core for real-time space applications

Video-based navigation is an increasingly used procedure with hard real-time requirements and high computational effort. In this field, FPGA hardware accelleration supplyes low-cost and considerable performances enhancement. The video-based navigation algorithms extrapolate and correlates features from images, relying on their accuracy. Image enhancement provides more defined and contrasted frames, assuring high precision feature extraction. This work introduces an FPGA-based self-adaptive image enhancer. The IP-core is suitable for hard-real time applications, such as space applications, thanks to the guaranteed high-throughpu