Upper limb amputation in the course of skin metastases of rectal cancer

Zaledwie u około 4% pacjentów z przerzutowym rakiem jelita grubego stwierdza się przerzuty skórne. Są one złym czynnikiem prognostycznym ze względu na często towarzyszący rozsiew do narządów wewnętrznych, zwykle będący przyczyną zgonu. Przedstawiono przypadek 82-letniego chorego, którego zakwalifikowano do chemioterapii paliatywnej z zastosowaniem fluorouracylu i leukoworyny z powodu rozsiewu raka obytnicy do kości, płuc i skóry dłoni i przedramienia lewego, który nastąpił 4 lata po radykalnym leczeniu ogniska pierwotnego. U pacjenta wstępnie przeprowadzono paliatywną radioterapię zmian przerzutowych do kości kończyny dolnej lewej. Po pierwszym kursie chemioterapii stwierdzono ustąpienie krwawienia ze zmian skórnych i nasilenie martwicy w ich obrębie. Tuż po zakończeniu drugiego kursu z powodu masywnego krwawienia ze zmian skórnych amputowano kończynę górną lewą. Z powodu potwierdzonych zmian przerzutowych do mózgu chorego poddano paliatywnej radioterapii ośrodkowego układu nerwowego (OUN) i zakończono leczenie systemowe. Przerzuty nowotworowe do skóry rzadko są przyczyną poważnych komplikacji klinicznych, ale ze względu na możliwe infekcje i krwawienia stają się czasem powodem pogorszenia jakości życia pacjenta, a wyjątkowo mogą prowadzić do zgonu. Istotne jest więc nie tylko przyczynowe, specjalistyczne leczenie choroby nowotworowej, ale także postępowanie objawowe adekwatne do sytuacji klinicznej chorego.Skin metastases occur in 4% patients with metastatic colorectal cancer. They are interpretated as unfavourable prognostic factor. as accompanying multi-organ metastases which are more often the death cause. The authors are presenting the case of 82 years old patient qualified to pallitive chemotherapy with fluorouracyl and leucovorin due to rectal cancer metasteses to bones, lungs, and hand and lower arm skin in 4 years after radical therapy of focus primarius . The patient underwent palliative radiotherapy of bone metatstases to left arm. After first course of chemotherapy the bleeding from the skin metastases stopped and the necrosis increased. After the second chemotherapy course, the left arm amputation was done due to massive bleeding from the skin lesion. After confirming CNS metastases the brain was irradiated palliatively and the systemic therapy was finished. Skin metastases rarely can lead to severe clinical complications (eg. death) but because of potential infections and bleeding can decrease the patients´ quality of life. Therefore not only high qualified therpay of cancer is needed but adequate symptoms managemnet as well

The rp-process and new measurements of beta-delayed proton decay of light Ag and Cd isotopes

Recent network calculations suggest that a high temperature rp-process could explain the abundances of light Mo and Ru isotopes, which have long challenged models of p-process nuclide production. Important ingredients to network calculations involving unstable nuclei near and at the proton drip line are $\beta$-halflives and decay modes, i.e., whether or not $\beta$-delayed proton decay takes place. Of particular importance to these network calculation are the proton-rich isotopes $^{96}$Ag, $^{98}$Ag, $^{96}$Cd and $^{98}$Cd. We report on recent measurements of $\beta$-delayed proton branching ratios for $^{96}$Ag, $^{98}$Ag, and $^{98}$Cd at the on-line mass separator at GSI.Comment: 4 pages, uses espcrc1.sty. Proceedings of the 4th International Symposium Nuclei in the Cosmos, June 1996, Notre Dame/IN, USA, Ed. M. Wiescher, to be published in Nucl.Phys.A. Also available at ftp://ftp.physics.ohio-state.edu/pub/nucex/nic96-gs

Hindered E4 decay of the 12+ yrast trap in 52Fe

AbstractThe γ decay of the 12+ yrast trap in 52Fe has been measured for the first time. The two E4 γ-branches to the 8+ states are hindered with respect to other B(E4) reduced transition probabilities measured in the f7/2 shell. The interpretation of the data is given in the full pf shell model framework, comparing the results obtained with different residual interactions. It is shown that measurements of hexadecapole transition probabilities constitute a powerful tool in discriminating the correct configuration of the involved wavefunctions

Hindered E4 decay of the 12+ yrast trap in 52Fe

Abstract The γ decay of the 12 + yrast trap in 52Fe has been measured for the first time. The two E4 γ-branches to the 8 + states are hindered with respect to other B ( E 4 ) reduced transition probabilities measured in the f 7 / 2 shell. The interpretation of the data is given in the full pf shell model framework, comparing the results obtained with different residual interactions. It is shown that measurements of hexadecapole transition probabilities constitute a powerful tool in discriminating the correct configuration of the involved wavefunctions

Fine structure of the Gamow-Teller resonance revealed in the decay of Ho-150 2(-) isomer

The γ rays following the 72s 150Ho 2- Gamow-Teller β decay have been investigated with the CLUSTER CUBE setup, an array of six EUROBALL CLUSTER Ge detectors in close cubic geometry, providing a γ ray detection sensitivity of 2×10-5 per β-parent decay for γ-ray energies up to 5 MeV. The fine structure of the Gamow-Teller resonance at 4.4-MeV excitation in 150Dy has been studied. The resolved levels are compared with Shell Model predictions

LAMINATION OF HAND-MADE PAPERS

Under certain conditions the hand-made papers manufactured from rag fibres are exposed to attacks of micro-organisms thus suffering the degradation of cellulose content in fibres. Papers so contaminated are gradually loosing their original mechanical strength. * At the end of the 19th century a method has been found for strengthening of weakened papers by their lining with artificial parchment glued on by means of the starch glues. However, with the passing time artificial parchment is getting more and more brittle and looses its transparency whereas its removing from the weakened paper becomes very difficult and causes several considerable troubles. The weakened papers can also be laminated with silk chiffon or Japanese tissue paper, but here the faults common for the both methods of lamination consist in — difficulties to strip the linings from their beds in the case of need, advancing flavescence, loss of mechanical strength, and the susceptibility of starch glues to the action of micro- organisms and insects. All the above factors necessitate the considering of possibilities to apply other methods of lamination for hand-made papers. Method of lamination using acetylcellulose foil worked out by Barrow and its modifications applied successfully in several countries can be considered as proper one for lamination of machine-made papers, and in particular those containing groundwood. However, the hand-made papers change their texture apparently after processing of their surfaces. Lamination with the use of acetylcellulose foil partially solved in acetone appears to be a better method in application for old papers since it eliminates the need for high temperature and pressure but the acetylcellulose foil of high quality is required for this purpose. In the National Main Archiv of Old Record, Warsaw a method has been developed for lamination using the acetone solution of a c e ty lcellulose. The solution is rubbed on the paper and tissue paper by means of a painter’s brus/h enabling to laminate the paper on both sides or on one side only. However, the lamination on both sides is more labour-consuming operation and leads to the increased paper thickness but at the same time provides the higher mechanical strength. In the course of lamination by means of acetylcellulose acetone solution the toxic and highly inflammable vapours arise. Similar to the above method is lamination using the methylcellulose solution. The aqueous solution of methylcellulose is entirely odourless. The principle of lamination procedure is much the same as in the case of starch glue lamination with this sole exception that paper laminated with methylcellulose is much more resistant to the attacking microorganisms and at the same time shows considerable improvement of its mechanical strength