Methodological guide for the selection of the disposal sites of the overhead materials product of the disappearance, excavation, cutting and / or demolition performed in the projects of road infrastructure.

El objetivo general del trabajo de investigación es desarrollar una guía metodológica para la selección de los sitios de disposición de los materiales sobrantes (en adelante ZODMES) producto de las actividades realizadas en los proyectos de infraestructura vial en Colombia, para el logro de este objetivo se desarrolló inicialmente la identificación de los criterios técnicos, ambientales y sociales para la caracterización y selección de los ZODMES, arrojando así por cada componente diferentes criterios que influyen en la toma de decisiones con relación a la identificación y posterior selección de ZODMES. Así mismo, se determina por medio del trabajo investigativo el cumplimiento de la normatividad legal vigente aplicable a los sitios de disposición final de material sobrante, identificando los trámites, permisos y/o autorizaciones ambientales y sociales requeridas al momento de selección un sitio de disposición, de otra parte, para el componente técnico se especificaron las normas y manuales técnicos relacionados, esto con el propósito de consolidar la normatividad aplicable a cada una de las etapas de diseño de un ZODME.The general objective of the research work is a methodological guide for the selection of sites for the disposal of leftover materials (onwardsfor its acronyms in spanish ZODMES) product of the activities carried out in road infrastructure projects in Colombia, in order to achieve this objective. in making decisions regarding the identification and subsequent selection of ZODMES. Likewise, it will be determined through the investigative work the fulfillment of the current legal regulations applicable to the sites of final disposal of the remaining material, identifying the procedures, permits and / or environmental and social authorizations required at the time of the selection of a site of On the other hand, for the technical component, the norms and related technical manuals will be specified, this with the purpose of consolidating the regulations applicable to each one of the design stages of a ZODME.Universidad libre - Facultad de ingeniería - Especialización en Gerencia Ambienta

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Saber pedagógico en Corporeidad, bienestar y socioemocionalidad

Digital p. 186-Primera edició

Stroke etiologies in patients with COVID-19 : the SVIN COVID-19 multinational registry

Coronavirus disease 2019 (COVID-19) is associated with a small but clinically significant risk of stroke, the cause of which is frequently cryptogenic. In a large multinational cohort of consecutive COVID-19 patients with stroke, we evaluated clinical predictors of cryptogenic stroke, short-term functional outcomes and in-hospital mortality among patients according to stroke etiology. We explored clinical characteristics and short-term outcomes of consecutively evaluated patients 18 years of age or older with acute ischemic stroke (AIS) and laboratory-confirmed COVID-19 from 31 hospitals in 4 countries (3/1/20-6/16/20). Of the 14.483 laboratory-confirmed patients with COVID-19, 156 (1.1%) were diagnosed with AIS. Sixty-one (39.4%) were female, 84 (67.2%) white, and 88 (61.5%) were between 60 and 79 years of age. The most frequently reported etiology of AIS was cryptogenic (55/129, 42.6%), which was associated with significantly higher white blood cell count, c-reactive protein, and D-dimer levels than non-cryptogenic AIS patients (p</=0.05 for all comparisons). In a multivariable backward stepwise regression model estimating the odds of in-hospital mortality, cryptogenic stroke mechanism was associated with a fivefold greater odds in-hospital mortality than strokes due to any other mechanism (adjusted OR 5.16, 95%CI 1.41-18.87, p = 0.01). In that model, older age (aOR 2.05 per decade, 95%CI 1.35-3.11, p < 0.01) and higher baseline NIHSS (aOR 1.12, 95%CI 1.02-1.21, p = 0.01) were also independently predictive of mortality. Our findings suggest that cryptogenic stroke among COVID-19 patients carries a significant risk of early mortality. The online version contains supplementary material available at 10.1186/s12883-021-02075-

Dimensiones del hábitat popular latinoamericano

Estos textos nacen de la necesidad de guardar la memoria de un proceso de trabajo sobre dos temas de importancia para América Latina y el Caribe como son el hábitat popular y la inclusión social; tópicos con nombres tan propios en cada lugar de nuestra región –favelas, villas miseria, pueblos jóvenes, etc. Los libros analizan las condiciones y mecanismos de gestión y de acceso al suelo urbano y a la vivienda de calidad en nuestras ciudades poco democráticas y sin garantías; y por otro lado, indagan cómo nacen los hacedores, hombres y mujeres, en su vida cotidiana y en sus actividades de producción y reproducción social.Índice Presentación . . . . . . . . . 9 Prólogo . . . . . . . . . . . . 11 Teolinda Bolívar y Jaime Erazo Espinosa CAPÍTULO I. ANÁLISIS Y EFECTOS DE POLÍTICAS IMPLEMENTADAS EN AMÉRICA LATINA: COLOMBIA Y BRASIL ¿Ciudad prioritaria, ciudad social? Análisis de la política nacional de vivienda para familias de bajos ingresos en Bogotá (1991-2009) . . . . . 19 Óscar A. Alfonso R. Programas de regularización y formación de las plusvalías en las urbanizaciones informales . . . . . . 45 Por Antônio Augusto Veríssimo Capítulo II. Inter/secciones de la ciudad y el hábitat popular Nota introductoria al capítulo II . . . . . . . . . . 69 Benjamin Nahoum Mega crecimiento urbano de la ciudad de Panamá y su impacto sobre el hábitat y la vivienda popular . . . . . . . 75 Carlos David Castro-Gómez Habitar nuevos barrios de interés social en el área metropolitana de Buenos Aires: el espacio construido por el Estado y vivido por los vecinos . . . . . . . 101 María Cristina Cravino Las adversidades del hábitat en conjuntos habitacionales de población relocalizada . . . . . . . . . 121 Walter Fernando Brites Vivienda popular y seguridad pública: el proceso de “pacificación” en las favelas de Río de Janeiro . . . . . . . 143 Neiva Vieira da Cunha Capítulo III. Derecho a la ciudad, crisis y demandas ciudadanas Nota introductoria al capítulo IIII . . . . . . . . . 165 Pablo Vitale Derecho a la ciudad: personas sin hogar en la ciudad de Buenos Aires . . . . . 171 Griselda Palleres La participación ciudadana en la construcción de hábitat incluyente y sostenible: hacia la materialización del derecho a la ciudad . . . . . . . . . . . 187 Laura Cedrés Pérez La cuestión habitacional: crisis financieras, naturales, institucionales y de derechos . . . . . . . . . . 209 Ana Raquel Flores Capítulo IV. Problemas relacionados entre espacio público y hábitat Nota introductoria al capítulo IV . . . . . . . 237 Andrés Forero Perilla Disputas urbanas: el espacio y la diferenciación en el barrio . . . . . . . . 245 Laura Paniagua Arguedas El espacio público como derecho a la ciudad. Un recorrido por el patrimonio del centro histórico de Quito . . . . . . 267 Sonia Cueva Ortiz Pobreza urbana y desigualdad: la asistencia habitacional a personas en situación de calle en la ciudad de Buenos Aires . . . . . . . 295 Paula Cecilia Rosa Las representaciones femeninas del espacio urbano. Nuevas demandas para la construcción democrática e incluyente de la ciudad . . . . . . . . 311 María Antonieta Urquieta A. y Claudia Campillo T. Capítulo V. Mercados de suelo y vivienda: regularización y propiedad Nota introductoria . . . . . . . . . . . . 331 Oscar Ospina L. Aproximaciones para la reestructuración física y social de la vivienda popular en barrios de Caracas . . . . . . . . . . . . . . 337 Carmenofelia Machado Colmenares La encrucijada de la vivienda de interés social en Bogotá . . . . . . . . . . 353 Alex Smith Araque Solano y Yadira Caballero Quintero ¿Ser o no ser propietario? Notas en torno a la regularización de asentamientos precarios . . . . . . . . 403 María Laura Canestraro La necesidad de consolidar el derecho a la ciudad repensando los paradigmas de la titulación . . . . 423 Miguel Cavero Velaochaga Propiedad del suelo urbanizado: del derecho individual a la finalidad social. Prescribir lo que se abandona . . . . . 441 María Araceli Schettini, Eduardo Gandelman y Benjamín Nahoum Lotización irregular en Quito: impunidad y conflictividad social . . . . 465 Paula Castello Starkoff y Sonia Cueva Ortiz ANEXOS Grupo de Trabajo Hábitat Popular e Inclusión Social. Parte 2 I Reunión y I Congreso Latinoamericano y Caribeño de Hábitat Popular e Inclusión Social, Quito, del 7 al 9 de abril de 2010 . . . . . . . . . . 485 Teolinda Bolívar y Jaime Erazo Espinosa Autores . . . . . . . . . 49

Biodiversidad 2018. Reporte de estado y tendencias de la biodiversidad continental de Colombia

Las cifras y temáticas contenidos en el presente Reporte, aunque no son el panorama completo del estado del conocimiento de la biodiversidad en Colombia, son un compendio seleccionado de los temas que, desde el Instituto Humboldt, consideramos son relevantes y merecen ser discutidos por el público general. En muchos de los casos, las cifras no son esperanzadoras u son un llamado urgente a la acción. En otro casos son la evidencia de que se requieren acciones a nivel nacional, y más allá de esto, son muchas las iniciativas que están germinando desde los territorios, cada vez desde una mayor variedad de actores.Bogotá, D. C., Colombi

RecruitNet: A global database of plant recruitment networks

Plant recruitment interactions (i.e., what recruits under what) shape the composition, diversity, and structure of plant communities. Despite the huge body of knowledge on the mechanisms underlying recruitment interactions among species, we still know little about the structure of the recruitment networks emerging in ecological communities. Modeling and analyzing the community-level structure of plant recruitment interactions as a complex network can provide relevant information on ecological and evolutionary processes acting both at the species and ecosystem levels. We report a data set containing 143 plant recruitment networks in 23 countries across five continents, including temperate and tropical ecosystems. Each network identifies the species under which another species recruits. All networks report the number of recruits (i.e., individuals) per species. The data set includes >850,000 recruiting individuals involved in 118,411 paired interactions among 3318 vascular plant species across the globe. The cover of canopy species and open ground is also provided. Three sampling protocols were used: (1) The Recruitment Network (RN) protocol (106 networks) focuses on interactions among established plants (“canopy species”) and plants in their early stages of recruitment (“recruit species”). A series of plots was delimited within a locality, and all the individuals recruiting and their canopy species were identified; (2) The paired Canopy-Open (pCO) protocol (26 networks) consists in locating a potential canopy plant and identifying recruiting individuals under the canopy and in a nearby open space of the same area; (3) The Georeferenced plot (GP) protocol (11 networks) consists in using information from georeferenced individual plants in large plots to infer canopy-recruit interactions. Some networks incorporate data for both herbs and woody species, whereas others focus exclusively on woody species. The location of each study site, geographical coordinates, country, locality, responsible author, sampling dates, sampling method, and life habits of both canopy and recruit species are provided. This database will allow researchers to test ecological, biogeographical, and evolutionary hypotheses related to plant recruitment interactions. There are no copyright restrictions on the data set; please cite this data paper when using these data in publications

Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts.[Design]: We assessed 18,566 participants in the “Seguimiento Universidad de Navarra” (SUN) cohort followed-up during 188,891 person-years and 6790 participants in the “PREvencion con DIeta MEDiterránea” (PREDIMED) randomized trial representing 30,233 person-years of follow-up. DII scores were calculated in both cohorts from validated FFQs. Higher DII scores corresponded to more proinflammatory diets. A total of 230 and 302 deaths occurred in SUN and PREDIMED, respectively. In a random-effect meta-analysis we included 12 prospective studies (SUN, PREDIMED and 10 additional studies) that assessed the association between DII scores and all-cause mortality.[Results]: After adjusting for a wide array of potential confounders, the comparison between extreme quartiles of the DII showed a positive and significant association with all-cause mortality in both the SUN (hazard ratio [HR] = 1.85; 95% CI: 1.15, 2.98; P-trend = 0.004) and the PREDIMED cohort (HR = 1.42; 95% CI: 1.00, 2.02; P-trend = 0.009). In the meta-analysis of 12 cohorts, the DII was significantly associated with an increase of 23% in all-cause mortality (95% CI: 16%–32%, for the highest vs lowest category of DII).[Conclusion]: Our results provide strong and consistent support for the hypothesis that a pro-inflammatory diet is associated with increased all-cause mortality. The SUN cohort and PREDIMED trial were registered at clinicaltrials.gov as NCT02669602 and at isrctn.com as ISRCTN35739639, respectively.Supported by the official funding agency for biomedical research of the Spanish Government, Instituto de Salud Carlos III (ISCIII), through grants provided to research networks specifically developed for the trial (RTIC G03/140, to R.E.; RTIC RD 06/0045, to Miguel A. Martínez-González) and through Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERobn), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigación Sanitaria–Fondo Europeo de Desarrollo Regional (Proyecto de Investigación (PI) 04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, P11/02505, PI13/00462, PI13/00615, PI13/01090, PI14/01668, PI14/01798, PI14/01764), Ministerio de Ciencia e Innovación (Recursos y teconologia agroalimentarias(AGL)-2009-13906-C02 and AGL2010-22319-C03 and AGL2013-49083-C3-1- R), Fundación Mapfre 2010, the Consejería de Salud de la Junta de Andalucía (PI0105/2007), the Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana (Generalitat Valenciana Ayuda Complementaria (GVACOMP) 06109, GVACOMP2010-181, GVACOMP2011-151), Conselleria de Sanitat y, PI14/01764 AP; Atención Primaria (CS) 2010-AP-111, and CS2011-AP-042), and Regional Government of Navarra (P27/2011).). Drs. Shivappa and Hébert were supported by grant number R44DK103377 from the United States National Institute of Diabetes and Digestive and Kidney Diseases