45 research outputs found

    Usage pattern of Library Resources and Services by the Students and Faculty Members of B.Ed Colleges Affiliated to Kuvempu University

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    This study explores user perception, the use of an academic library, and the correlation between user perception and library use. The findings indicate that the B.Ed College library is a preferred place to study and spend time during non-class times on campus. The frequent user activities in the library included individual study, reading, computer use, finding information, group study, using reference and information services, and meeting and socializing. The correlation between library use and each of the user activities was examined. The findings suggest that users perceive the B.Ed College library primarily as a place for learning and information seeking. The study shows how users perceive and use the library, and provides insights into how libraries can strengthen their place and advance their role in the academic community

    Knowledge and use of electronic information resources by Post graduate Engineering students of Karnataka state: A study

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    The present study is an attempt to know the knowledge and use of electronic information resources by post graduate engineering students studying in 16 Autonomous engineering colleges of Karnataka state. The study involved 1064 post graduate engineering students and found that 100% students use electronic information resources. The study also revealed that e-journals are the most preferred e-resources and the library notice board along with library websites are the major sources of creating awareness about the availability of e-resources. However, the trial and error method was highly used to use e-resources followed by self-study and library orientation. The study found that keyword search is highly preferred and the VTU consortium is a highly preferred gateway for accessing the e-resources. Engineering students lack the skill of selecting the right search term. Apart from this slow internet connectivity also hinders the effective use of e-resources

    User Satisfaction of Library Resources and Services: A Survey of Pre- University College Teachers in Karnataka, India

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    Present study examines the user satisfaction of library resources and services: A survey of pre-university college teachers in Karnataka, India. Well structured questionnaires were distributed among 125 teachers to collect their opinions regarding the frequency and purpose of visit to the library. Study also highlights the available information resources and services. From the study we found that the majority of the respondents 65 (63.73%) are male followed by female respondents 37 (36.27%). It is also observed that 86 (84.31%) respondents are from rural area. About 35.29% respondents are happy with availability of text books in library. It was found that 58.82% of respondents feel good with circulation service. Further an attempt has been made to give few suggestions based on the analysis of the data

    Medicine Research in India: A Scientometric Assessment of Publications during 2009 – 2018

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    The purpose of this paper is to qualitative analyse of medicine research output using select scientometric indicators with the aim of identifying top preparing countries, subject subthemes, organisations, authors and journals in the area. The present study has examined 29153 publications in medicine research, the present study deals with the Assessment of Indian medicine research output as reflected in Web of Science (WOS) database for the period 2009 to 2018 for identifying the research output in the field of medicine literature. It also provides a comparative evaluation and performance of different types of scientometric indicators, such as number of publications, number of citations, relative growth, doubling time, activity index and collaboration from India. The Indian medicine research has increased exponentially over the last decade

    PERCEPTION AND USAGE OF HEALTH INFORMATION SOURCES AND SERVICES AMONG THE URBAN COMMUNITY USERS OF PUBLIC LIBRARIES: A CASE STUDY OF BHADRAVATHI

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    The study examined the perception and usage of health information sources and services by the urban community users of public libraries. The study investigated 110 users from two public libraries in Bhadravathi. Findings revealed that majority of the users not enrolling library membership. 44.54% of users were visit library daily and large numbers of respondents were get health information through newspaper followed by television, advertisements and pamphlet/brochures. Education and sports were the most frequently preferred topics by the users. Arogya column published by Prajavani Kannada newspaper was most preferred newspaper column for getting health information by the users followed by VK Health column published by Vijaya Karnataka was stood in 2nd position to get health information by the users. Most of the users preferred Sudha, Gruhashobha and Taranga magazines to get health information. Stimulatingly, large number of the users frequently listen health related programs in Radio. The study also revealed that most of the users were aware about H1N1, DPT, Polio, BCG, TT, AIDS Control, 108 Arogya Kavacha, Malaria Cholera Dengue, Family Planning, Chicken Gunya district health programs of Karnataka state

    On the recurrence of Noctiluca scintillans bloom in Minnie Bay, Port Blair: Impact on water quality and bioactivity of extracts

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    A Noctiluca scintillans bloom in the coastal waters of Minnie Bay, Port Blair was studied. Physico-chemical and biological properties of bloom-infested waters were monitored during the bloom period lasting five days. The bloom appeared as a green streak along the entire coastline of Minnie Bay, with cell counts of 17 103 cells/ l. The bloom appeared as a sudden spurt in cell number and persisted for a period of 48 h. The antibacterial properties of extracts from this algal species were also investigated. Conspicuously, the bloom inhibited the common resident phytoplankton species. Total suspended solids showed a marked increase during day-one of bloom compared to ambient levels. The bloom appeared to be limited by dissolved inorganic nitrogen species availability. The differential growth of phytoplankton reveals the involvement of specific trigger factors for such blooms. From the present viewpoint, micro-scale studies on hydrobiological factors preceding the onset of bloom would reveal what cycle of events lead to a bloom and the causal factors of such blooms. However, prediction of occurrence of such blooms and in situ measurements are practical difficulties to be addressed. Since a similar bloom was reported earlier in 2001, it is worthwhile to keep a watch and investigate as to whether there is any anthropogenic or environmental cause for the recurrence of the bloom

    Facts and Treatment of Bullous Pemphigoid: A Review

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    Bullous pemphigoid (a type of pemphigoid) is an autoimmune pruritic skin disease that typically occurs in people aged over 60, that may involve the formation of blisters (bullae) in the space between the epidermal and dermal skin layers. It is classified as a type II hypersensitivity reaction, which involves formation of anti-hemidesmosome antibodies, causing a loss of keratinocytes to basement membrane adhesion. Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and in pemphigoid, the basal keratinocytes lose adhesion to the basement membrane. Pemphigus lesions are mediated directly by the autoantibodies, whereas the autoantibodies in pemphigoid fix complement and mediate inflammation. In both diseases, the autoantigens have been cloned and characterized; pemphigus antigens are desmogleins (cell adhesion molecules in desmosomes), and pemphigoid antigens are found in hemidesmosomes (which mediate adhesion to the basement membrane). This knowledge has enabled diagnostic testing for these diseases by enzyme-linked immunosorbent assays and dissection of various pathophysiological mechanisms, including direct inhibition of cell adhesion, antibody-induced internalization of antigen, and cell signaling. Understanding these mechanisms of disease has led to rational targeted therapeutic strategies

    Assessment of phytoplankton diversity, distribution, and environmental variables along the southeast coast of India

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    Coastal waters are dynamic because of anthropogenic activities that contribute nutrients and contaminants. These changes have the potential to alter patterns of primary production and thus pelagic food webs. Here, we investigated the spatial variation of the phytoplankton community and its response to changing environmental variables at 84 stations along the five coastal districts of Tamil Nadu (TN). During the present study, 85 phytoplankton species were recorded, such as diatoms (64), dinoflagellates (18), silicoflagellates (1), and Cyanophyceae (2). The maximum phytoplankton abundance was recorded on the Thanjavur coast and gradually decreased towards the south coast of Tamil Nadu. Among the phytoplankton community, 50% was dominated by pennate diatoms, attributed to higher NO3− concentrations in the coastal waters due to agricultural discharge. Cluster analysis revealed that Ramanathapuram and Tirunelveli formed a closed cluster, whereas Thanjavur and Pudukottai formed a separate closed cluster associated with higher nutrient and metal concentrations, highlighting the difference in physicochemical parameters between the northern and southern districts of the TN coast. Relatively high nutrient concentrations in the coastal waters of northern districts are of greater concern, which could impact the coastal ecosystem. Coastal eutrophication is becoming a widespread phenomenon, causing disruption in the food chain and ecosystem balances and hence requiring regular monitoring and management

    Pharmacoinformatic investigation of medicinal plants from East Africa

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    Medicinal plants have widely been used in the traditional treatment of ailments and have been proven effective. Their contribution still holds an important place in modern drug discovery due to their chemical, and biological diversities. However, the poor documentation of traditional medicine, in developing African countries for instance, can lead to the loss of knowledge related to such practices. In this study, we present the Eastern Africa Natural Products Database (EANPDB) containing the structural and bioactivity information of 1870 unique molecules isolated from about 300 source species from the Eastern African region. This represents the largest collection of natural products (NPs) from this geographical region, covering literature data of the period from 1962 to 2019. The computed physicochemical properties and toxicity profiles of each compound have been included. A comparative analysis of some physico-chemical properties like molecular weight, H-bond donor/acceptor, logP(o/w), etc. as well scaffold diversity analysis has been carried out with other published NP databases. EANPDB was combined with the previously published Northern African Natural Products Database (NANPDB), to form a merger African Natural Products Database (ANPDB), containing similar to 6500 unique molecules isolated from about 1000 source species (freely available at http://african-compounds.org). As a case study, latrunculins A and B isolated from the spongeNegombata magnifica(Podospongiidae) with previously reported antitumour activities, were identified via substructure searching as molecules to be explored as putative binders of histone deacetylases (HDACs)

    Gabapentin for chronic pelvic pain in women (GaPP2):a multicentre, randomised, double-blind, placebo-controlled trial

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    BackgroundChronic pelvic pain affects 2–24% of women worldwide and evidence for medical treatments is scarce. Gabapentin is effective in treating some chronic pain conditions. We aimed to measure the efficacy and safety of gabapentin in women with chronic pelvic pain and no obvious pelvic pathology.MethodsWe performed a multicentre, randomised, double-blind, placebo-controlled randomised trial in 39 UK hospital centres. Eligible participants were women with chronic pelvic pain (with or without dysmenorrhoea or dyspareunia) of at least 3 months duration. Inclusion criteria were 18–50 years of age, use or willingness to use contraception to avoid pregnancy, and no obvious pelvic pathology at laparoscopy, which must have taken place at least 2 weeks before consent but less than 36 months previously. Participants were randomly assigned in a 1:1 ratio to receive gabapentin (titrated to a maximum dose of 2700 mg daily) or matching placebo for 16 weeks. The online randomisation system minimised allocations by presence or absence of dysmenorrhoea, psychological distress, current use of hormonal contraceptives, and hospital centre. The appearance, route, and administration of the assigned intervention were identical in both groups. Patients, clinicians, and research staff were unaware of the trial group assignments throughout the trial. Participants were unmasked once they had provided all outcome data at week 16–17, or sooner if a serious adverse event requiring knowledge of the study drug occurred. The dual primary outcome measures were worst and average pain scores assessed separately on a numerical rating scale in weeks 13–16 after randomisation, in the intention-to-treat population. Self-reported adverse events were assessed according to intention-to-treat principles. This trial is registered with the ISRCTN registry, ISCRTN77451762.FindingsParticipants were screened between Nov 30, 2015, and March 6, 2019, and 306 were randomly assigned (153 to gabapentin and 153 to placebo). There were no significant between-group differences in both worst and average numerical rating scale (NRS) pain scores at 13–16 weeks after randomisation. The mean worst NRS pain score was 7·1 (standard deviation [SD] 2·6) in the gabapentin group and 7·4 (SD 2·2) in the placebo group. Mean change from baseline was −1·4 (SD 2·3) in the gabapentin group and −1·2 (SD 2·1) in the placebo group (adjusted mean difference −0·20 [97·5% CI −0·81 to 0·42]; p=0·47). The mean average NRS pain score was 4·3 (SD 2·3) in the gabapentin group and 4·5 (SD 2·2) in the placebo group. Mean change from baseline was −1·1 (SD 2·0) in the gabapentin group and −0·9 (SD 1·8) in the placebo group (adjusted mean difference −0·18 [97·5% CI −0·71 to 0·35]; p=0·45). More women had a serious adverse event in the gabapentin group than in the placebo group (10 [7%] of 153 in the gabapentin group compared with 3 [2%] of 153 in the placebo group; p=0·04). Dizziness, drowsiness, and visual disturbances were more common in the gabapentin group.InterpretationThis study was adequately powered, but treatment with gabapentin did not result in significantly lower pain scores in women with chronic pelvic pain, and was associated with higher rates of side-effects than placebo. Given the increasing reports of abuse and evidence of potential harms associated with gabapentin use, it is important that clinicians consider alternative treatment options to off-label gabapentin for the management of chronic pelvic pain and no obvious pelvic pathology.FundingNational Institute for Health Research
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