Successful Management of a Cornual Pregnancy with a Single High-Dose Laparoscopic Methotrexate Injection

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Methotrexate Therapy For Ectopic Pregnancies: A Tertiary Center Experience

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Chemotherapy During Pregnancy: Cases Of Hodgkin'S And Non-Hodgkin'S Lymphoma, Chronic Myeloid Leukemia, Breast Cancer, Nasopharyngeal Cancer, And Choriocarcinoma

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Hemorroidas E Complicações Relacionadas Na Gestação De Primigestas

ABSTRACT Purpose: To identify the effect of pregnancy on the development of external hemorrhoids and constipation. Subjects and methods: This pilot study involved 61 primigravid women without a history of perianal diseases. Each patient was examined and filled a questionnaire between the 11th and 14th gestational week prior to prenatal screening tests. Patients were re-examined and questioned in relation to perianal symptoms and hemorrhoidal changes again in the 24th and 37th gestational weeks. Results: A total of 5, 8, and 11 women had symptomatic external hemorrhoids with or without perianal complications in the 11-14th, 24th, and 37th gestational weeks, respectively. Meanwhile, 27, 25, and 29 women complained about constipation in the 11-14th, 24th, and 37th gestational weeks, respectively. Only 4 (6.6%) patients experienced painful hemorrhoids. The overall morbidity rate was 18% (11 cases). We found a statistically significant relationship between external hemorrhoids/perianal complications and gestation-induced constipation through logistic regression analysis (p < 0.001). Conclusion: Various risk factors and biological explanations exist for the high frequency of hemorrhoids during pregnancy. Because participants were primigravid women without a history of perianal complaints, findings suggest a direct effect of pregnancy itself on the development of external hemorrhoids/perianal symptoms