THE IMPACT OF FDI, EXPORT, ECONOMIC GROWTH, TOTAL FIXED INVESTMENT ON UNEMPLOYMENT IN TURKEY

The impact of Foreign Direct Investment, export, economic growth and total fixed investment on unemployment in Turkey for the period of 1987-2007 was examined. Johansen cointegration technique was applied to determine long run relationship. The empirical findings suggest that there are two cointegrating vectors during the concerned period of time in Turkey

Cytotoxicity and apoptotic effects of nickel oxide nanoparticles in cultured HeLa cells.

The aim of this study was to observe the cytotoxicity and apoptotic effects of nickel oxide nanoparticles on human cervix epithelioid carcinoma cell line (HeLa). Nickel oxide precursors were synthesized by an nickel sulphate-excess urea reaction in boiling aqueous solution. The synthesized NiO nanoparticles

Effect of Employee Participation and Patient Focus Approaches in the Scope of TQM on Hospital Performance

WOS:000568989100014In this study, it was aimed to investigate the effect of employee participation and patient focus, which are included in the total quality approach of 33 private hospitals within the borders of Ankara, on the performance of the hospital. Accordingly, relational screening model was used in the research. The universe of the research consists of senior managers such as chief physicians, chief assistants, hospital managers, hospital manager assistants, quality coordinators of 33 private hospitals actively serving within the borders of Ankara. Interviews were made with 308 hospital senior managers. Questionnaire was used as a data collection tool in quantitative research methods. In the research, face-to-face interviews were made with hospital managers. SPSS20 program was used in the analysis of research data. Introductory characteristics of hospital managers are shown with frequency and percentage. Participants' assessments of the scales are indicated with the mean and standard deviation. In the research, the effect of employee participation and patient focus on hospital performance within the scope of total quality management (TQM) was investigated by multiple linear regression analysis. The research data were evaluated within the 95% confidence interval. As a result, it was determined that employee participation and patient focus practices within the scope of TQM played an active role on hospital performance and positively affected them. In the study, they stated that private hospital managers gave high scores for employee participation and patient focus dimensions and that these processes were followed in their hospitals. In addition, administrators expressed a positive opinion about the performances of private hospitals

Parametric cost estimation system for light rail transit and metro trackworks

WOS: 000284863200170The main objective of this work is to develop early cost estimation models for light rail transit and metro trackworks using the multivariable regression and artificial neural network approaches. These two approaches were applied to a data set of 16 projects by using 17 parameters available at the early design phase. The regression analysis estimated the cost of testing samples with an error of 2.32%. On the other hand, artificial neural network estimated the cost with 5.76% error, which was slightly higher than the regression error. As a result, two successful cost estimation models have been developed depending on the findings of this paper. These models can effectively be utilized in the tender decision-making phase of projects with trackworks. (C) 2010 Elsevier Ltd. All rights reserved

Usefulness of CA 15-3 for breast or ovarian primary sites in metastatic adenocarcinoma of pleural fluid

Kilic, Murat/0000-0002-1377-2021WOS: 000302197000005This study was conducted to evaluate the diagnostic value of CA 15-3, mammaglobin, c-erbB-2, estrogen receptor (ER), progesterone receptor (PR), CK 20, and CA 125 for detecting metastatic breast and ovarian carcinoma in pleural fluids. The material under study consisted of 26 pleural effusions from invasive breast and ovarian cancer patients from the Hannover Cytopathology Institute. Expressions of these markers were studied using immunocytochemistry. All of the breast cancer cases studied showed a positive reaction with CA 15-3, while only 36% with mammaglobin, 21% with c-erbB-2, 36% with ER, and 7% with PR were positive. The sensitivities of CK 20, CA 15-3, and CA 125 as markers for metastatic ovarian carcinoma were 43%, 88%, and 55%, respectively. Our results indicate that CA 15-3 has a higher sensitivity than other tumor markers for diagnosing metastatic breast and ovarian carcinoma in pleural fluids

Pharmacokinetics of florfenicol after intravenous and intramuscular administration in New Zealand White rabbits

The pharmacokinetic disposition and bioavailability of florfenicol (FF) were determined after single intravenous (i.v.) and intramuscular (i.m.) administrations of 25 mg/kg b.w. to ten healthy New Zealand White rabbits. Plasma FF concentrations were determined by high-performance liquid chromatography (HPLC). The plasma pharmacokinetic values for FF were best described by a one-compartment open model. The elimination half-life (t(1/2 beta)) was different (p 0.05) after i.v. and i.m. administrations. FF was rapidly eliminated (t(1/2 beta) 1.49 +/- 0.23 h), slowly absorbed and high (F, 88.75 +/- 0.22%) after i.m. injection. In addition, FF was widely distributed to the body tissues (V-ss 0.98 +/- 0.05 L/kg) after im. injection. In this study the time that plasma concentration exceeded the concentration of 2 mu g/mL was approximately 6 h. For bacteria with MIC of 2 mu g/mL, frequent administration at this dose would be needed to maintain the concentration above the MIC. However, it is possible that rabbit pathogens may have MIC values less than 2 mu g/mL which would allow for less frequent administration. Further studies are necessary to identify the range of MIC values for rabbit pathogens and to identify the most appropriate PK-PD parameter needed to predict an effective dose. Crown Copyright (C) 2008 Published by Elsevier Ltd. All rights reserved

Over-The-Top Knot Placement Technique Enhances Tensile Stability of Tendon Repairs

Background: Currently a major concern for the surgical treatment of Achilles tendon rupture repairs is the creation of stable enough fixation to allow early range of motion. It was documented that the weakest point in a suture loop is the knot. Thus, we hypothesized that moving the knot away from the repair junction (over-the-top Krackow technique) would increase the strength of the repair. Materials and Methods: Transected bovine tendons were repaired by the traditional Krackow and over-the-top Krackow techniques using four suture materials (Fiberwire Nos. 5 and 2, Ethibond Nos. 5 and 2). Tendons were cyclically tested at incremental loads beginning from 50 N until 5-mm gap formation. Then all tendons were loaded to failure. The number of cycles to 5-mm gapping, ultimate failure loads and knot slip were compared using t-test and Mann-Whitney tests (with Tukey corrections for multiple comparisons). Results: Mean number of cycles to 5-mm gapping did not reveal significant differences (p = 0.113) between repair groups. Mean failure load of tendons repaired by over-the-top Krackow technique were significantly higher (p < 0.0001) for all four paired groups than tendons repaired by traditional Krackow technique. Ethibond No. 5, No. 2, and Fiberwire No. 2 suture repairs with over-the-top configuration did not reveal any knot slip. Conclusion: Over-the-top Krackow technique increases the ultimate failure load of repaired tendons. But 5-mm gapping resistivity was not enhanced either by the technique or the suture material. Clinical Relevance: The knot itself is a stress-riser in the suture loop so we suggest that freeing it from tension by our modificiation may achieve more durable repairs

Cytotoxicity and apoptotic effects of nickel oxide nanoparticles in cultured HeLa cells

The aim of this study was to observe the cytotoxicity and apoptotic effects of nickel oxide nanoparticles on humancervix epithelioid carcinoma cell line (HeLa). Nickel oxide precursors were synthesized by an nickel sulphate-excess ureareaction in boiling aqueous solution. The synthesized NiO nanoparticles (<200 nm) were investigated by X-ray diffractionanalysis and transmission electron microscopy techniques. For cytotoxicity experiments, HeLa cells were incubated in50-500 μg/mL NiO for 2, 6, 12 and 16 hours. The viable cells were counted with a haemacytometer using light microscopy.The cytotoxicity was observed low in 50-200 μg/mL concentration for 16 h, but high in 400-500 μg/mL concentration for2-6 h. HeLa cells' cytoplasm membrane was lysed and detached from the well surface in 400 μg/mL concentration NiOnanoparticles. Double staining and M30 immunostaining were performed to quantify the number of apoptotic cells in cultureon the basis of apoptotic cell nuclei scores. The apoptotic effect was observed 20% for 16 h incubation