5,314 research outputs found

    Postemergence application of herbicides in corn

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    The Iowa 2006 corn crop is mostly in the ground and much of it will be emerged by the end of the week. Planting progressed rapidly in late April prior to the current wet conditions, and this prolonged wet period will impact weed management plans for those fields planted prior to the rain but not treated with preemergence herbicides or nitrogen (N) fertilizer. This article is revised from a 2003 discussion and will describe two important issues

    Enquiry Pull Research: An Ethnomethodological Approach to Lean Construction Research or a Lean Approach to Ethnomethodological Research

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    This paper assembles some principals from three strands of thought: lean theory; ethnomethodology; and Wittgensteinian philosophy. These are considered with a view to their impact on research design and used here as a basis for an initial exploration of a candidate research topic, in order to illustrate this impact. Principles of Lean Theory are considered, along with those from Wittgensteinian social enquiry and Ethnomethodology, in order to suggest a strategy for Lean Research. These are applied to the intial consideration of a candidate research topic, in order to illustrate the argument

    PROVIDING A MEETING REMINDER TO AN INVITEE NOT IN ATTENDANCE AT A MEETING

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    How often, in this busy world in which we work, has a meeting invitee forgotten to join a meeting (in time or at all)? Let\u27s be honest—it happens all the time and sometimes it\u27s important that a particular invitee is present, particularly for meetings in which other attendees are relying on the invitee\u27s input during a meeting. Techniques presented herein provide for the ability for an absent invitee for a meeting to receive a reminder to join the potentially forgotten and, more importantly, potentially vital meeting when the absent invitee\u27s name is mentioned during the meeting

    Bacteria Source Tracking to Support Watershed Planning, Little Sac River, Southwest Missouri

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    The Little Sac Watershed in Greene and Polk Counties of southwest Missouri was placed on the 303d list for bacteria impairment in 1998 (WCO 2016). In 2006, a Total Maximum Daily Load (TMDL) was developed for the watershed to address bacteria impairments within the Little Sac River and an initial watershed management plan was finalized in 2010 (Baffaut 2006, WCO 2009). The Watershed Committee of the Ozarks (WCO) is presently updating that plan with the most recent information on bacteria within the watershed. As part of that process, the WCO has contracted the Ozarks Environmental and Water Resources Institute (OEWRI) at Missouri State University (MSU) to complete a bacteria source tracking study within the watershed to identify potential bacteria pollution sources. The purpose of this study is to collect water samples throughout the watershed and evaluate bacteria DNA using real-time PCR for specific marker genes that can help identify specific bacteria sources from different locations in the Little Sac River watershed

    Specific inhibition of binding of antistasin and [A103,106,108] antistasin 93–119 to sulfatide (Gal(3-SO4)β1-1Cer) by glycosaminoglycans

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    AbstractLeech-derived antistasin is a potent anticoagulant and antimetastatic protein that binds sulfatide (Gal(3-SO4)β1-1Cer)and sulfated polysaccharides. In this study, the synthetic fragment [A103,106,108] antistasin 93–119, which corresponds to the carboxyl terminus, showed specific and saturable binding to sulfatide. Binding was competitively blocked by glycosaminoglycans (GAGs) in the order: dextran sulfate 5000 ≅ dextran sulfate 500 0OO > heparin > dermatan sulfate ⪢ chondroitin sulfates A and C. This rank order of inhibitory potency was identical to that observed with whole antistasin. We suggest that residues 93–119 of antistasin represent a critical domain for binding GAGs and sulfated glycolipids

    N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis

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    The presence of the neuronal-specific N1-Src splice variant of the C-Src tyrosine kinase is conserved through vertebrate evolution, suggesting an important role in complex nervous systems. Alternative splicing involving a N1-Src specific microexon leads to a five or six amino acid insertion into the SH3 domain of Src. A prevailing model suggests that N1-Src regulates neuronal differentiation via cytoskeletal dynamics in the growth cone. Here we have investigated the role of n1-src in the early development of the amphibian Xenopus tropicalis, and find that n1-src expression is regulated in embryogenesis, with highest levels detected during the phases of primary and secondary neurogenesis. In situ hybridisation analysis, using locked nucleic acid (LNA) oligo probes complementary to the n1-src microexon indicate that n1-src expression is highly enriched in the open neural plate during neurula stages and in the neural tissue of adult frogs. Given the n1-src expression pattern, we investigated a possible role for n1-src in neurogenesis. Using splice site-specific antisense morpholino oligos, we are able to inhibit n1-src splicing, whilst preserving c-src expression. Differentiation of neurons in the primary nervous system is reduced in n1-src knockdown embryos, accompanied by a severely impaired touch response in later development. These data reveal an essential role for n1-src in amphibian neural development and suggest that alternative splicing of C-Src in the developing vertebrate nervous system evolved to regulate neurogenesis

    Radiocarbon record of solar variability and Holocene climatic change in coastal southern California

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    EXTRACT (SEE PDF FOR FULL ABSTRACT): Pollen analysis and 5 radiocarbon dates for a 687-cm core provide a detailed chronology of environmental change for San Joaquin Marsh at the head of Newport Bay, Orange County, California. Sediment deposition kept pace with sea level rise during the mid-Holocene, but after 4500 years BP, sea water regularly reached the coring site, and salt marsh was the local vegetation. Brief periods of dominance by fresh-water vegetation 3800, 2800, 2300 and after 560 years BP correlate global cooling events and (except the 3800-year BP event) with carbon-14 production anomalies. The coincidence of climate change and carbon-14 anomalies support a causal connection with solar variability, but regardless of the causal mechanism(s) the delta-carbon-14 curves provide a chronology for global, high-frequency climatic change comparable to that of Milankovitch cyclicity for longer time scales

    N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis

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    The presence of the neuronal-specific N1-Src splice variant of the C-Src tyrosine kinase is conserved through vertebrate evolution, suggesting an important role in complex nervous systems. Alternative splicing involving a N1-Src specific microexon leads to a five or six amino acid insertion into the SH3 domain of Src. A prevailing model suggests that N1-Src regulates neuronal differentiation via cytoskeletal dynamics in the growth cone. Here we have investigated the role of n1-src in the early development of the amphibian Xenopus tropicalis, and find that n1-src expression is regulated in embryogenesis, with highest levels detected during the phases of primary and secondary neurogenesis. In situ hybridisation analysis, using locked nucleic acid (LNA) oligo probes complementary to the n1-src microexon indicate that n1-src expression is highly enriched in the open neural plate during neurula stages and in the neural tissue of adult frogs. Given the n1-src expression pattern, we investigated a possible role for n1-src in neurogenesis. Using splice site-specific antisense morpholino oligos, we are able to inhibit n1-src splicing, whilst preserving c-src expression. Differentiation of neurons in the primary nervous system is reduced in n1-src knockdown embryos, accompanied by a severely impaired touch response in later development. These data reveal an essential role for n1-src in amphibian neural development and suggest that alternative splicing of C-Src in the developing vertebrate nervous system evolved to regulate neurogenesis

    Sagittarius A* Small Satellite Mission: Capabilities and Commissioning Preview

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    SSCI is leading a Defense Advanced Research Projects Agency (DARPA)-funded team launching a mission in June 2021, dubbed Sagittarius A*, to demonstrate key hardware and software technologies for on-orbit autonomy, to provide a software testbed for on-orbit developmental test & autonomous mission operations, and to reduce risk for future constellation-level mission autonomy and operations. In this paper, we present the system CONOPs and capabilities, system architectures, flight and ground software development status, and initial commissioning status. The system will fly on Loft Orbital’s YAM-3 shared LEO satellite mission, and includes SSCI’s onboard autonomy software suite running on an Innoflight CFC-400 processor with onboard Automatic Target Recognition (ATR). The autonomy payload has attitude control authority over the spacecraft bus and command authority of the imaging payload, and performs fully-autonomous onboard request handling, resource & task allocation, collection execution, ATR, and detection downlinking. The system is capable of machine-to -machine tip-and-cue from offboard cueing sources via cloud-based integrations. Requests for mission data are submitted to the satellite throughout its orbit from a tactical user level via a smartphone application, and ISR data products are downlinked and displayed at the tactical level on an Android Tactical Assault Kit (ATAK) smartphone. Follow-on software updates can be sent to the autonomy suite as over-the-air updates for on-orbit testing at any time during the on-orbit life of the satellite. Communications include GlobalStar inter-satellite communications for low rate task and status monitoring, and ground station links for payload data downloads. Planned demonstrations and opportunities will be discussed
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