Vitamin B12 induced acneiform eruption

A 47-year-old, north african, male patient, has recently been diagnosed with pernicious anemia, treated with weekly intramuscular hydroxocobalamin. 6 weeks after its initiation, the patient presented a sudden, extensive and monomorphic eruption of inflammatory papulo-pustules and nodules, affecting the face, and the trunk. The eruption was pruritic, and comedones were also present, on the chest. The patient was diagnosed with vitamin B12-induced acneiform eruption. Levels of vitamin B12 were normalized. Hydroxocobalamin was therefore stopped and lymecycline was started, allowing a complete resolution of the lesions within 3 months. Drug intake, sudden and uncommon age of onset, pruritus, a monomorphic pattern and an involvement of extra-seborrheic areas are features that distinguish acneiform eruptions from acne vulgaris

Corneal Manifestations of Tuberculosis: About 2 Cases

Abstract Corneal tuberculosis is a rare ophthalmic manifestation of tuberculosis. The purpose of this study is to present clinical and histopathological findings in two cases of corneal tuberculosis. We reported corneal manifestation of tuberculosis in two patients including granulomatous lesion at upper third of the cornea in the first case, and sectorial interstitial keratitis in the second one. The diagnosis was based on various anamnestic, clinical, histological and evolutive arguments. An anti-tuberculosis treatment was prescribed

Acquired Immunodeficiency Syndrome Revealed by Oral Kaposi’s Sarcoma

Kaposi’s sarcoma is the malignant proliferation of the endothelial cell vessels. It is a systemic, malignant and multifactor disease. It usually presents initially as violaceous cutaneous lesions. Outside of a known context of an immune deficiency, an isolated oral lesions may not think to Kaposi’s sarcoma. Hence the interest of the histological and immunohistochemical study. This paper reviews one such case of Kaposi’s sarcoma in a 42-year-old woman who present an isolated pigmented lesions of the tongue, related to Kaposi’s sarcoma, without cutaneous or visceral involvement, and which led to the discovery of acquired immunodeficiency syndrome (HIV). The stabilization was obtained with antiretroviral triple therapy.</p