821 research outputs found
Similarity Analysis of Projectile Penetration into Concrete
This paper presents a dimensionless model for the depth of penetration (DOP) of a projectile penetrating into a concrete target, based on the similarity theory involving intermediate asymptotics, complete similarity, and incomplete similarity. The calculated numerical results are in good agreement with previous experimental data, including two sets of full-scale and twenty-four sets of sub-scale penetration of non-deformable projectiles into concrete targets. Moreover, compared with several empirical and semi-empirical DOP models, the new model is applicable within a relatively broader range, including the penetration of both sub-scale and full-scale projectiles. For the limitations of the validity, dimensionless parameters Π3 = ϕt/ϕ larger than 12, Π4 = (ϕ3fc)/(Mv02) smaller than 0.1, and the initial impact velocity of the projectile less than about 900 to 1000m/s are necessary for the model
Lighting up the LHC with Dark Matter
We show that simultaneously explaining dark matter and the observed value of
the muon's magnetic dipole moment may lead to yet unexplored photon signals at
the LHC. We consider the Minimal Supersymmetric Standard Model with
electroweakino masses in the few-to-several hundred GeV range, and opposite
sign of the Bino mass parameter with respect to both the Higgsino and Wino mass
parameters. In such region of parameter space, the spin-independent elastic
scattering cross section of a Bino-like dark matter candidate in direct
detection experiment is suppressed by cancellations between different
amplitudes, and the observed dark matter relic density can be realized via
Bino-Wino co-annihilation. Moreover, the observed value of the muon's magnetic
dipole moment can be explained by Bino and Wino loop contributions.
Interestingly, "radiative" decays of Wino-like neutralinos into the lightest
neutralino and a photon are enhanced, whereas decays into leptons are
suppressed. While these decay patterns weaken the reach of multi-lepton
searches at the LHC, the radiative decay opens a new window for probing dark
matter at the LHC through the exploration of parameter space regions beyond
those currently accessible. To complement the current electroweakino searches,
we propose searching for a single (soft) photon plus missing transverse energy,
accompanied by a hard initial state radiation jet
The Efficacy of Chinese Herbal Medicine as an Adjunctive Therapy for Advanced Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis
Many published studies reflect the growing application of complementary and alternative medicine, particularly Chinese herbal medicine (CHM) use in combination with conventional cancer therapy for advanced non-small cell lung cancer (NSCLC), but its efficacy remains largely unexplored. The purpose of this study is to evaluate the efficacy of CHM combined with conventional chemotherapy (CT) in the treatment of advanced NSCLC. Publications in 11 electronic databases were extensively searched, and 24 trials were included for analysis. A sum of 2,109 patients was enrolled in these studies, at which 1,064 patients participated in CT combined CHM and 1,039 in CT (six patients dropped out and were not reported the group enrolled). Compared to using CT alone, CHM combined with CT significantly increase one-year survival rate (RR = 1.36, 95% CI = 1.15-1.60, p = 0.0003). Besides, the combined therapy significantly increased immediate tumor response (RR = 1.36, 95% CI = 1.19-1.56, p<1.0E-5) and improved Karnofsky performance score (KPS) (RR = 2.90, 95% CI = 1.62-5.18, p = 0.0003). Combined therapy remarkably reduced the nausea and vomiting at toxicity grade of III-IV (RR = 0.24, 95% CI = 0.12-0.50, p = 0.0001) and prevented the decline of hemoglobin and platelet in patients under CT at toxicity grade of I-IV (RR = 0.64, 95% CI = 0.51-0.80, p<0.0001). Moreover, the herbs that are frequently used in NSCLC patients were identified. This systematic review suggests that CHM as an adjuvant therapy can reduce CT toxicity, prolong survival rate, enhance immediate tumor response, and improve KPS in advanced NSCLC patients. However, due to the lack of large-scale randomized clinical trials in the included studies, further larger scale trials are needed. © 2013 Li et al.published_or_final_versio
[1-(4-Chlorophenyl)-5-hydroxy-3-phenyl-1H-pyrazol-4-yl](thiophen-2-yl)methanone
In the title compound, C20H13ClN2O2S, the chlorophenyl, phenyl and thienoyl rings are oriented at dihedral angles 17.84 (7), 53.13 (8) and 34.03 (8)°, respectively, to the central pyrazole ring. An intramolecular O—H⋯O hydrogen bond occurs. In the crystal, pairs of bifurcated O—H⋯O hydrogen bonds link molecules into inversion dimers with R
2
2(12) graph-set motifs
Tell Me How to Survey: Literature Review Made Simple with Automatic Reading Path Generation
Recent years have witnessed the dramatic growth of paper volumes with plenty
of new research papers published every day, especially in the area of computer
science. How to glean papers worth reading from the massive literature to do a
quick survey or keep up with the latest advancement about a specific research
topic has become a challenging task. Existing academic search engines such as
Google Scholar return relevant papers by individually calculating the relevance
between each paper and query. However, such systems usually omit the
prerequisite chains of a research topic and cannot form a meaningful reading
path. In this paper, we introduce a new task named Reading Path Generation
(RPG) which aims at automatically producing a path of papers to read for a
given query. To serve as a research benchmark, we further propose SurveyBank, a
dataset consisting of large quantities of survey papers in the field of
computer science as well as their citation relationships. Each survey paper
contains key phrases extracted from its title and multi-level reading lists
inferred from its references. Furthermore, we propose a
graph-optimization-based approach for reading path generation which takes the
relationship between papers into account. Extensive evaluations demonstrate
that our approach outperforms other baselines. A Real-time Reading Path
Generation System (RePaGer) has been also implemented with our designed model.
To the best of our knowledge, we are the first to target this important
research problem. Our source code of RePaGer system and SurveyBank dataset can
be found on here.Comment: 16 pages, 12 figure
Local and remote forcing of interannual sea‐level variability at Nantucket Island
© The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Wang, O., Lee, T., Piecuch, C., Fukumori, I., Fenty, I., Frederikse, T., Menemenlis, D., Ponte, R., & Zhang, H. Local and remote forcing of interannual sea‐level variability at Nantucket Island. Journal of Geophysical Research: Oceans, 127(6), (2022): e2021JC018275, https://doi.org/10.1029/2021jc018275.The relative contributions of local and remote wind stress and air-sea buoyancy forcing to sea-level variations along the East Coast of the United States are not well quantified, hindering the understanding of sea-level predictability there. Here, we use an adjoint sensitivity analysis together with an Estimating the Circulation and Climate of the Ocean (ECCO) ocean state estimate to establish the causality of interannual variations in Nantucket dynamic sea level. Wind forcing explains 67% of the Nantucket interannual sea-level variance, while wind and buoyancy forcing together explain 97% of the variance. Wind stress contribution is near-local, primarily from the New England shelf northeast of Nantucket. We disprove a previous hypothesis about Labrador Sea wind stress being an important driver of Nantucket sea-level variations. Buoyancy forcing, as important as wind stress in some years, includes local contributions as well as remote contributions from the subpolar North Atlantic that influence Nantucket sea level a few years later. Our rigorous adjoint-based analysis corroborates previous correlation-based studies indicating that sea-level variations in the subpolar gyre and along the United States northeast coast can both be influenced by subpolar buoyancy forcing. Forward perturbation experiments further indicate remote buoyancy forcing affects Nantucket sea level mostly through slow advective processes, although coastally trapped waves can cause rapid Nantucket sea level response within a few weeks.This research was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration (80NM0018D0004). CGP was supported by NASA Sea Level Change Team awards 80NSSC20K1241 and 80NM0018D0004
catena-Poly[[bis(μ2-4-aminobenzenesulfonato-κ2 O:O)disilver]-bis(μ2-4,4′-bipyridine-κ2 N:N′)]
In the title compound, [Ag2(C6H6NO3S)2(C10H8N2)2]n, the AgI atom is four-coordinated by two N atoms from two symmetry-related 4,4′-bipyridine (bipy) and two O atoms from two independent 4-aminobenzenesulfonate (ABS) ligands. The two inter-chain AgI atoms are bridged by two independent ABS ligands through weak Ag—O bonds and Ag⋯Ag attractions, forming a ladder-like chain coordination polymer [Ag2(ABS)2(bipy)2]n parallel to [001], which is further linked to generate a two-dimensional structure via N—H⋯O hydrogen-bonding interactions
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