3,406 research outputs found

    Evolution of A Distributed Live, Virtual, Constructive Environment for Human in the Loop Unmanned Aircraft Testing

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    NASA's Unmanned Aircraft Systems Integration in the National Airspace System Project is conducting human in the loop simulations and flight testing intended to reduce barriers associated with enabling routine airspace access for unmanned aircraft. The primary focus of these tests is interaction of the unmanned aircraft pilot with the display of detect and avoid alerting and guidance information. The project's integrated test and evaluation team was charged with developing the test infrastructure. As with any development effort, compromises in the underlying system architecture and design were made to allow for the rapid prototyping and open-ended nature of the research. In order to accommodate these design choices, a distributed test environment was developed incorporating Live, Virtual, Constructive, (LVC) concepts. The LVC components form the core infrastructure support simulation of UAS operations by integrating live and virtual aircraft in a realistic air traffic environment. This LVC infrastructure enables efficient testing by leveraging the use of existing assets distributed across multiple NASA Centers. Using standard LVC concepts enable future integration with existing simulation infrastructure

    Remaining Fatigue Lifetime Prediction for Retirement-for-Cause in Metals

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    A methodology is evaluated to predict the probability of specimen failure with subsequent fatigue, after a short surface crack has been detected in Al 2219-T851 alloy. Cracks are detected and tracked to failure using optical microscopy. Predictions of remaining lifetime distributions are made with a Monte Carlo procedure in conjunction with growth laws which model the effect of grains of differing size, shape and crystallographic orientation in the crack path on propagation rate. Because the surface of the alloy cyclically hardens, the average rate of crack growth is less for cracks formed later during fatigue. The predictive methodology successfully describes this phenomenon, as well as predicts the probability of early failure arising from the statistical nature of the growth process, for failure probabilities substantially smaller than conveniently measureable in the laboratory

    Message Latency Characterization of a Distributed Live, Virtual, Constructive Simulation Environment

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    A distributed test environment incorporating Live, Virtual, Constructive, (LVC) concepts was developed to execute standalone and integrated simulations and flight-tests that support unmanned aircraft research for NASAs Unmanned Aircraft Systems (UAS) in the National Airspace System (NAS) Project. The LVC components form the core infrastructure that supports simulation of UAS operations by integrating live and virtual aircraft in a realistic air traffic environment. This LVC infrastructure enables efficient testing by leveraging the use of existing distributed assets. The LVC concepts used for the UAS in the NAS project include live aircraft, flight simulators, and virtual air traffic control assets operating at facilities distributed across multiple NASA Centers. With a distributed network, however, there is a concern that message latency could impact the realism of a simulation and its data. The latencies associated with sending data among these distributed facilities were, therefore, measured to ensure that they fall within acceptable parameters. Several live and virtual test assets were integrated into the LVC infrastructure including NASA Armstrongs Ikhana MQ-9 unmanned aircraft, NASA Glenns S3-B manned aircraft, and the B747 flight simulator at NASA Ames. Average latencies from 100 to 150 milliseconds were observed between the LVC System running at NASA Ames and each of the participating NASA Centers under a light-to-moderate (fifty aircraft) traffic sample

    Economic Impacts from Increasing Pig Farrowing in Iowa

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    Hog production has historically been a significant, value-adding industry in Iowa. Sales of finishing hogs can result in gross income in the range of 2.5billionannually.Theeconomicactivitywouldbegreaterasthereareimpactsonupstreamanddownstreamsectorsoftheeconomy.Accountingfortheseimpactsleadstoagenerationofmorethan2.5 billion annually. The economic activity would be greater as there are impacts on upstream and downstream sectors of the economy. Accounting for these impacts leads to a generation of more than 3 billion of annual gross product in Iowa. Throughout the past three decades, the swine breeding herd in Iowa has experienced a decreasing trend, with relatively sharp declines coming since the early 1990’s. Producers have increasingly looked to other parts of North America for a supply of feeder pigs. This reflects a lost opportunity for the Iowa pork production industry. This study evaluates the viability and economic impact of expanding the number of sows farrowed in Iowa. We estimate the impacts to the aggregate state economy from a revival of pig farrowing. Our estimates of costs and returns to farrowing show the potential to generate much value added profit. These profits would benefit farm owners, managers, input suppliers, and processors, etc. These impacts will ripple throughout the economy including rural communities. A 5 million head increase in SEW pig production would require approximately 238,000 additional sows. The feed bill would be about 30millionwhilethelaborbillwouldbeabout30 million while the labor bill would be about 35 million. The income earned by employees and to those that sold the feed etc. goes toward buying other goods and services, multiplying the overall economic impact. In aggregate the addition of 5 million feeder/SEW pigs would produce $270 million of economic activity. A large part of this would occur in rural communities

    Multiple foil lunar environmental analyser (FLEA package) for the evaluation of meteoroid primary impact penetration, radiant, velocity and composition, meteoroid impact ejecta and comminution products, solar wind composition, medium energy solar flare composition, solar wind sputter rate, meteoroid bumper efficiency

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    The conception of a multiple thin foil sensor has been investigated and is suggested as a very valuable tool for the accumulation of data over long exposure periods on the lunar surface. Data will lead to the evaluation of specific parameters of the meteor environment, of the solar wind spectrum and of the overall environmental erosion rates from both impact and sputtering.by J.A.M. McDonnell and Otto E. Berg.Summary -- Introduction -- Proposal -- Scientific background -- Environmental stability of FLEA system -- Data evaluation -- Support details and personne

    Critical current degradation in HTS wires due to cyclic mechanical strain

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    HTS wires, which may be used in many devices such as magnets and rotating machines, may be subjected to mechanical strains from electromagnetic, thermal and centripetal forces. In some applications these strains will be repeated several thousand times during the lifetime of the device. We have measured critical current degradation due to repeated strain cycles for both compressive and tensile strains. Results for BSCCO-2223 HTS conductor samples are presented for strain values up to 0.5% and cycle numbers up to and beyond 10/sup 4/

    The impact of malaria parasites on dendritic cell–T cell interaction

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    Malaria is caused by apicomplexan parasites of the genus Plasmodium. While infection continues to pose a risk for the majority of the global population, the burden of disease mainly resides in Sub-Saharan Africa. Although immunity develops against disease, this requires years of persistent exposure and is not associated with protection against infection. Repeat infections occur due to the parasite's ability to disrupt or evade the host immune responses. However, despite many years of study, the mechanisms of this disruption remain unclear. Previous studies have demonstrated a parasite-induced failure in dendritic cell (DCs) function affecting the generation of helper T cell responses. These T cells fail to help B cell responses, reducing the production of antibodies that are necessary to control malaria infection. This review focuses on our current understanding of the effect of Plasmodium parasite on DC function, DC-T cell interaction, and T cell activation. A better understanding of how parasites disrupt DC-T cell interactions will lead to new targets and approaches to reinstate adaptive immune responses and enhance parasite immunity

    A new multi-center approach to the exchange-correlation interactions in ab initio tight-binding methods

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    A new approximate method to calculate exchange-correlation contributions in the framework of first-principles tight-binding molecular dynamics methods has been developed. In the proposed scheme on-site (off-site) exchange-correlation matrix elements are expressed as a one-center (two-center) term plus a {\it correction} due to the rest of the atoms. The one-center (two-center) term is evaluated directly, while the {\it correction} is calculated using a variation of the Sankey-Niklewski \cite{Sankey89} approach generalized for arbitrary atomic-like basis sets. The proposed scheme for exchange-correlation part permits the accurate and computationally efficient calculation of corresponding tight-binding matrices and atomic forces for complex systems. We calculate bulk properties of selected transition (W,Pd), noble (Au) or simple (Al) metals, a semiconductor (Si) and the transition metal oxide TiO2O_2 with the new method to demonstrate its flexibility and good accuracy.Comment: 17 pages, 5 figure

    NMFS / Interagency Working Group Evaluation of CITES Criteria and Guidelines.

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    EXECUTIVE SUMMARY: At present, the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) criteria used to assess whether a population qualifies for inclusion in the CITES Appendices relate to (A) size of the population, (B) area of distribution of the population, and (C) declines in the size of the population. Numeric guidelines are provided as indicators of a small population (less than 5,000 individuals), a small subpopulation (less than 500 individuals), a restricted area of distribution for a population (less than 10,000 km2), a restricted area of distribution for a subpopula-tion (less than 500 km2), a high rate of decline (a decrease of 50% or more in total within 5 years or two generations whichever is longer or, for a small wild population, a decline of 20% or more in total within ten years or three generations whichever is longer), large fluctuations (population size or area of distribution varies widely, rapidly and frequently, with a variation greater than one order of magnitude), and a short-term fluctuation (one of two years or less). The Working Group discussed several broad issues of relevance to the CITES criteria and guidelines. These included the importance of the historical extent of decline versus the recent rate of decline; the utility and validity of incorporating relative population productivity into decline criteria; the utility of absolute numbers for defining small populations or small areas; the appropriateness of generation times as time frames for examining declines; the importance of the magnitude and frequency of fluctuations as factors affecting risk of extinction; and the overall utility of numeric thresh-olds or guidelines

    Cardiopulmonary exercise testing before and after intravenous iron in preoperative patients: a prospective clinical study

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    Background: Anemia is associated with impaired physical performance and adverse perioperative outcomes. Iron-deficiency anemia is increasingly treated with intravenous iron before elective surgery. We explored the relationship between exercise capacity, anemia, and total hemoglobin mass (tHb-mass) and the response to intravenous iron in anemic patients prior to surgery.// Methods: A prospective clinical study was undertaken in patients having routine cardiopulmonary exercise testing (CPET) with a hemoglobin concentration ([Hb]) < 130 g.l⁻¹ and iron deficiency/depletion. Patients underwent CPET and tHb-mass measurements before and a minimum of 14 days after receiving intravenous (i.v.) Ferric derisomaltose (Monofer®) at the baseline visit. Comparative analysis of hematological and CPET variables was performed pre and post-iron treatment.// Results: Twenty-six subjects were recruited, of whom 6 withdrew prior to study completion. The remaining 20 (9 [45%] male; mean ± SD age 68 ± 10 years) were assessed 25 ± 7 days between baseline and the final visit. Following i.v. iron, increases were seen in [Hb] (mean ± SD) from 109 ± 14 to 116 ± 12 g l⁻¹ (mean rise 6.4% or 7.3 g l⁻¹, p =  < 0.0001, 95% CI 4.5–10.1); tHb-mass from 497 ± 134 to 546 ± 139 g (mean rise 9.3% or 49 g, p =  < 0.0001, 95% CI 29.4–69.2). Oxygen consumption at anerobic threshold (V˙O2 AT) did not change (9.1 ± 1.7 to 9.8 ± 2.5 ml kg⁻¹ min⁻¹, p = 0.09, 95% CI − 0.13 − 1.3). Peak oxygen consumption (V˙O2 peak) increased from 15.2 ± 4.1 to 16 ± 4.4 ml.kg.⁻¹ min⁻¹, p = 0.02, 95% CI 0.2–1.8) and peak work rate increased from 93 [67–112] watts to 96 [68–122] watts (p = 0.02, 95% CI 1.3–10.8).// Conclusion: Preoperative administration of intravenous iron to iron-deficient/deplete anemic patients is associated with increases in [Hb], tHb-mass, peak oxygen consumption, and peak work rate. Further appropriately powered prospective studies are required to ascertain whether improvements in tHb-mass and performance in turn lead to reductions in perioperative morbidity
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