12 research outputs found
ALGORITHMIC APPROACH TO RESEARCH DIAGNOSTIC ACTIVITY PROBLEMS OF FUTURE CLASS TEACHER
Abstract. The article raises the problem of the diagnostic activity of a future class teacher. The problem fieldof the research object is shown. Based on the experience of psychological and pedagogical literature, they studied the algorithmic approach to the diagnostic activity of a teacher, and the concept of "diagnostic activity algorithm" was considered. It is proved that, despite the existing theoretical reserve, it is necessary to study the diagnostic activity of a future class teacher in connection with the specificity of his future educational activity. Based on the analysis of the ascertaining experiment results, a conclusion is drawn about the need to develop diagnostic tasks that are necessary in the educational activity of future class leaders. Also, the authors see the need for the algorithmization of diagnostic tasks, the purpose of which is to train future educators to reflect on their diagnostic activity, its timely correction, andfurther planning.Keywords: algorithm, algorithmic approach, diagnostics, diagnostic activity, future class teacher, the training of future teacher-educators
Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury
Background: Acute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass was associated with postoperative acute kidney injury in a large pediatric cohort. Methods: This was a retrospective analysis of patients under 1 year old undergoing cardiac surgery with cardiopulmonary bypass between January 1, 2013, and January 1, 2020. Receiver operating characteristic curves across values ranging from 260 to 400 mL/min/m2 were used to identify the indexed oxygen delivery most significantly associated with acute kidney injury risk. Results: We included 980 patients with acute kidney injury occurring in 212 (21.2%). After adjusting for covariates associated with acute kidney injury, an indexed oxygen delivery threshold of 340 mL/min/m2 predicted acute kidney injury in STAT 4 and 5 neonates (area under the curve = 0.66, 95% CI = 0.60 – 0.72, sensitivity = 56.1%, specificity = 69.4%). An indexed oxygen delivery threshold of 400 mL/min/m2 predicted acute kidney injury in STAT 1-3 infants (area under the curve = 0.65, 95% CI = 0.58 – 0.72, sensitivity = 52.6%, specificity = 74.6%). Conclusion: Indexed oxygen delivery during cardiopulmonary bypass is a modifiable variable independently associated with postoperative acute kidney injury in specific pediatric populations. Strategies aimed at maintaining oxygen delivery greater than 340 mL/min/m2 in complex neonates and greater than 400 mL/min/m2 in infants may reduce the occurrence of postoperative acute kidney injury in the pediatric population
Національна доповідь про стан і перспективи розвитку освіти в Україні: монографія (До 30-річчя незалежності України)
The publication provides a comprehensive analysis of the state and development of national education over the 30 years of Ukraine’s independence, identifies current problems in education, ascertains the causes of their emergence, offers scientifically reasoned ways to modernise domestic education in the context of globalisation, European integration, innovative development, and national self-identification.
Designed for legislators, state officials, education institutions leaders, teaching and academic staff, the general public, all those who seek to increase the competitiveness of Ukrainian education in the context of civilisation changes.У виданні здійснено всебічний аналіз стану і розвитку національної освіти за 30-річний період незалежності України, визначено актуальні проблеми освітньої сфери, виявлено причини їх виникнення, запропоновано науково обґрунтовані шляхи модернізації вітчизняної освіти в умовах глобалізації, європейської інтеграції, інноваційного розвитку та національної самоідентифікації. Розраховано на законодавців, державних управлінців, керівників закладів освіти, педагогічних і науково-педагогічних працівників, широку громадськість, усіх, хто прагне підвищення конкурентоспроможності української освіти в контексті цивілізаційних змін
Integrated Subject-Language Training of Students of Engineering Specialization Based on Digital Technologies
Modern Federal State Educational Standards, the State Program of the Russian Federation "Development of Education in 2018-2025 years" RF DoD Program "E-University" imposes the higher education system requirements to increase interdisciplinary interaction (Krylov, 2019; Coyle, Hood & Marsh, 2010) on the basis of digital technologies (Titova, 2017; Pearce et al., 2011). The aim of the research is the theoretical justification of the ideas of integrated subject - language training at higher educational institutions in domestic science, as well as the ideas of Language for Special Purposes – LSP, English for Specific Purposes – ESP, General English - GE Content and language integrated learning – CLIL developed by foreign researchers (Gardiner, 1998; March, 2000), the definition of scientific approaches in the process of implementing ideas subject-language training in higher education system of the Russian Federation, experimental verification of the effectiveness of the implementation of the subject-language training on the basis of digital technologies in the educational process of higher school. Research methods: theoretical analysis and systematization of psychological and pedagogical researches of domestic and foreign authors on the study; empirical: quantitative and qualitative analyses of questionnaires among students of senior courses. The study involved 87 students 4th– 5th year of specialist's degree.The results of the conducted experimental work confirmed effectiveness of the educational process based on integrated subject - language training on the basis of digital technologies, focused on interdisciplinary interaction of professional and foreign language meaningful components. The implementation of integrated subject - language training on the basis of digital technologies in the educational process of the University will help to provide interaction between professional theoretical knowledge and foreign language communicative practices, providing motivation for self-education; rational use of the budget of educational classroom time and time spent on extracurricular self-study, through the realization by students of the practical relevance of the acquired knowledge; variable course content that allows for a differentiated approach to students based on digital technologies. The practical significance of the results of the study is the possibility of their use in the development of curricula, work programs, further research on this issue
Integrated Subject-Language Training of Students of Engineering Specialization Based on Digital Technologies
Modern Federal State Educational Standards, the State Program of the Russian Federation "Development of Education in 2018-2025 years" RF DoD Program "E-University" imposes the higher education system requirements to increase interdisciplinary interaction (Krylov, 2019; Coyle, Hood & Marsh, 2010) on the basis of digital technologies (Titova, 2017; Pearce et al., 2011). The aim of the research is the theoretical justification of the ideas of integrated subject - language training at higher educational institutions in domestic science, as well as the ideas of Language for Special Purposes – LSP, English for Specific Purposes – ESP, General English - GE Content and language integrated learning – CLIL developed by foreign researchers (Gardiner, 1998; March, 2000), the definition of scientific approaches in the process of implementing ideas subject-language training in higher education system of the Russian Federation, experimental verification of the effectiveness of the implementation of the subject-language training on the basis of digital technologies in the educational process of higher school. Research methods: theoretical analysis and systematization of psychological and pedagogical researches of domestic and foreign authors on the study; empirical: quantitative and qualitative analyses of questionnaires among students of senior courses. The study involved 87 students 4th– 5th year of specialist's degree.The results of the conducted experimental work confirmed effectiveness of the educational process based on integrated subject - language training on the basis of digital technologies, focused on interdisciplinary interaction of professional and foreign language meaningful components. The implementation of integrated subject - language training on the basis of digital technologies in the educational process of the University will help to provide interaction between professional theoretical knowledge and foreign language communicative practices, providing motivation for self-education; rational use of the budget of educational classroom time and time spent on extracurricular self-study, through the realization by students of the practical relevance of the acquired knowledge; variable course content that allows for a differentiated approach to students based on digital technologies. The practical significance of the results of the study is the possibility of their use in the development of curricula, work programs, further research on this issue
Antibacterial Effect of Acoustic Cavitation Promoted by Mesoporous Silicon Nanoparticles
As-prepared mesoporous silicon nanoparticles, which were synthesized by electrochemical etching of crystalline silicon wafers followed by high-energy milling in water, were explored as a sonosensitizer in aqueous media under irradiation with low-intensity ultrasound at 0.88 MHz. Due to the mixed oxide-hydride coating of the nanoparticles’ surfaces, they showed both acceptable colloidal stability and sonosensitization of the acoustic cavitation. The latter was directly measured and quantified as a cavitation energy index, i.e., time integral of the magnitude of ultrasound subharmonics. The index turned out to be several times greater for nanoparticle suspensions as compared to pure water, and it depended nonmonotonically on nanoparticle concentration. In vitro tests with Lactobacillus casei revealed a dramatic drop of the bacterial viability and damage of the cells after ultrasonic irradiation with intensity of about 1 W/cm2 in the presence of nanoparticles, which themselves are almost non-toxic at the studied concentrations of about 1 mg/mL. The experimental results prove that nanoparticle-sensitized cavitation bubbles nearby bacteria can cause bacterial lysis and death. The sonosensitizing properties of freshly prepared mesoporous silicon nanoparticles are beneficial for their application in mild antibacterial therapy and treatment of liquid media
Do changes in socio-demographic characteristics impact up-to-date immunization status between 3 and 24 months of age? A prospective study among an inner-city birth cohort in the United States.
Introduction: Low-income child populations remain under-vaccinated. Our objective was to determine differences in the relative importance of maternal health literacy and socio-demographic characteristics that often change during early childhood on up-to-date (UTD) immunization status among a low-income population. Methods: We performed secondary data analysis of a longitudinal prospective cohort study of 744 Medicaid-eligible mother-infant dyads recruited at the time of the infant's birth from an inner-city hospital in the United States and surveyed every 6 months for 24 months. Our primary outcome was infant UTD status at 24 months abstracted from a citywide registry. We assessed maternal health literacy with the Test of Functional Health Literacy in Adults (short version). We collected socio-demographic information via surveys at birth and every 6 months. We compared predictors of UTD status at 3, 7, and 24 months. Results: The cohort consisted of primarily African-American (81.5%) mothers with adequate health literacy (73.9%). Immunizations were UTD among 56.7% of infants at 24 months of age. Maternal health literacy was not a significant predictor of UTD immunization status. Instead, adjusted results showed that significant predictors of not-UTD status at 24 months were lack of a consistent health care location or “medical home” (OR 0.17, 95%CI 0.18–0.37), inadequate prenatal care (OR 0.48, 95%CI 0.25–0.95), and prior not-UTD status (OR 0.31, 95%CI 0.20–0.47). Notably, all upper confidence limits are less than 1.0 for these variables. Health care location type (e.g., hospital-affiliate, community-based, none) was a significant predictor of vaccine status at age 3 months, 7 months, and 24 months. Conclusions: Investing in efforts to support early establishment of a medical home to obtain comprehensive coordinated preventive care, including providing recommended vaccines on schedule, is a prudent strategy to improve vaccination status at the population level
Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury
Background: Acute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass was associated with postoperative acute kidney injury in a large pediatric cohort. Methods: This was a retrospective analysis of patients under 1 year old undergoing cardiac surgery with cardiopulmonary bypass between January 1, 2013, and January 1, 2020. Receiver operating characteristic curves across values ranging from 260 to 400 mL/min/m2 were used to identify the indexed oxygen delivery most significantly associated with acute kidney injury risk. Results: We included 980 patients with acute kidney injury occurring in 212 (21.2%). After adjusting for covariates associated with acute kidney injury, an indexed oxygen delivery threshold of 340 mL/min/m2 predicted acute kidney injury in STAT 4 and 5 neonates (area under the curve = 0.66, 95% CI = 0.60 – 0.72, sensitivity = 56.1%, specificity = 69.4%). An indexed oxygen delivery threshold of 400 mL/min/m2 predicted acute kidney injury in STAT 1-3 infants (area under the curve = 0.65, 95% CI = 0.58 – 0.72, sensitivity = 52.6%, specificity = 74.6%). Conclusion: Indexed oxygen delivery during cardiopulmonary bypass is a modifiable variable independently associated with postoperative acute kidney injury in specific pediatric populations. Strategies aimed at maintaining oxygen delivery greater than 340 mL/min/m2 in complex neonates and greater than 400 mL/min/m2 in infants may reduce the occurrence of postoperative acute kidney injury in the pediatric population
Machine learning models for early sepsis recognition in the neonatal intensive care unit using readily available electronic health record data.
BackgroundRapid antibiotic administration is known to improve sepsis outcomes, however early diagnosis remains challenging due to complex presentation. Our objective was to develop a model using readily available electronic health record (EHR) data capable of recognizing infant sepsis at least 4 hours prior to clinical recognition.Methods and findingsWe performed a retrospective case control study of infants hospitalized ≥48 hours in the Neonatal Intensive Care Unit (NICU) at the Children's Hospital of Philadelphia between September 2014 and November 2017 who received at least one sepsis evaluation before 12 months of age. We considered two evaluation outcomes as cases: culture positive-positive blood culture for a known pathogen (110 evaluations); and clinically positive-negative cultures but antibiotics administered for ≥120 hours (265 evaluations). Case data was taken from the 44-hour window ending 4 hours prior to evaluation. We randomly sampled 1,100 44-hour windows of control data from all times ≥10 days removed from any evaluation. Model inputs consisted of up to 36 features derived from routine EHR data. Using 10-fold nested cross-validation, 8 machine learning models were trained to classify inputs as sepsis positive or negative. When tasked with discriminating culture positive cases from controls, 6 models achieved a mean area under the receiver operating characteristic (AUC) between 0.80-0.82 with no significant differences between them. Including both culture and clinically positive cases, the same 6 models achieved an AUC between 0.85-0.87, again with no significant differences.ConclusionsMachine learning models can identify infants with sepsis in the NICU hours prior to clinical recognition. Learning curves indicate model improvement may be achieved with additional training examples. Additional input features may also improve performance. Further research is warranted to assess potential performance improvements and clinical efficacy in a prospective trial
Contenu et perception de la notion de « langue de migrants » en France et en Russie
Une réflexion est menée ici sur le contenu sémantique des notions utilisées pour désigner la langue propre aux migrants. Plusieurs termes sont en effet en concurrence pour nommer la même réalité. L’objectif est d’essayer de comprendre le métalangage employé afin de le rendre plus accessible. Il est procédé à une analyse comparée du contenu notionnel attaché aux langues parlées par les migrants en français et en russe. La recherche est centrée en trois étapes sur le contenu morphologique et sémantique des notions employées~: collecter, trier et tester les combinaisons de variables. L’analyse linguistique des notions fait l’objet de trois approches~: morphologique, syntaxique et sémantique, les modifications morpho-syntaxiques et morpho-sémantiques ont des conséquences sémantiques sur la notion.Plus limité, le lexique russe est analysé en deux temps~: recensement et comparaison de l’utilisation des notions dans les deux langues. Le champ lexical et sémantique russe paraît plus précis et l’usage des préfixes plus fréquent (langue d’immigration/langue d’émigration).Cette analyse sert à comprendre une vision différente de l’approche sociolinguistique de ces langues