Private philanthropy or policy transfer? The transnational norms of the Open Society Institute

The Open Society Institute (OSI) is a private operating and grant-making foundation that serves as the hub of the Soros Foundations Network, a group of autonomous national foundations around the world. OSI is a mechanism for the international diffusion of expertise and ‘best practices’ to post-communist countries and other democratising nations. Focusing on the ‘soft’ ideational and normative policy transfer, the article highlights the engagement in governance that comes with OSI transnational policy partnerships

Double-pass technique and compensation-comparison method in eyes with cataract

PURPOSE To clinically assess the objective scatter index (OSI) obtained from double-pass images and the log(s) parameter measured with the direct compensation-comparison psychophysical technique in eyes with cataract. SETTING Ophthalmology Service, Terrassa Hospital, Barcelona, Spain. DESIGN Prospective observational case series. METHODS The analysis comprised eyes diagnosed with nuclear, cortical, or posterior subcapsular cataracts and healthy eyes (control group). Patient examinations included assessment of the manifest subjective refraction, corrected distance visual acuity, contrast sensitivity, and cataract grade using the Lens Opacities Classification System III (LOCS III) score. The protocol also included the straylight (log[s]) measured by the C-Quant device, measurement of the objective optical quality (Strehl ratio and modulation transfer function cutoff frequency), and the OSI (HD Analyzer). RESULTS Significant correlations with LOCS III classification were found in terms of log(s) and OSI, although they were slightly stronger with OSI for all cataract types, which could be attributable to higher-order aberrations. The OSI and log(s) shared approximately 44% of the scattering estimation and to coincide on the visual function decline with scattering for the 3 cataract types evaluated. Limits to discriminate between healthy and cataractous eyes and sensitivity and specificity values were 1.15 (sensitivity 91%, specificity 100%) for log(s) and 1.18 (sensitivity 89%, specificity 100%) for OSI (P < .05). CONCLUSIONS Both instruments provide complementary information to diagnose cataracts and follow patients. Although backscattered light from deeper retinal layers can have an effect on OSI, the double-pass image provides information to grade different types of cataract when assessing cataractous eyes for treatment.Preprin

Analgesic prescribing trends in a national sample of older veterans with osteoarthritis: 2012-2017

Few investigations examine patterns of opioid and nonopioid analgesic prescribing and concurrent pain intensity ratings before and after institution of safer prescribing programs such as the October 2013 Veterans Health Administration system-wide Opioid Safety Initiative (OSI) implementation. We conducted a quasi-experimental pre–post observational study of all older U.S. veterans (≥50 years old) with osteoarthritis of the knee or hip. All associated outpatient analgesic prescriptions and outpatient pain intensity ratings from January 1, 2012 to December 31, 2016, were analyzed with segmented regression of interrupted time series. Standardized monthly rates for each analgesic class (total, opioid, nonsteroidal anti-inflammatory drug, acetaminophen, and other study analgesics) were analyzed with segmented negative binomial regression models with overall slope, step, and slope change. Similarly, segmented linear regression was used to analyze pain intensity ratings and percentage of those reporting pain. All models were additionally adjusted for age, sex, and race. Before OSI implementation, total analgesic prescriptions showed a steady rise, abruptly decreasing to a flat trajectory after OSI implementation. This trend was primarily due to a decrease in opioid prescribing after OSI. Total prescribing after OSI implementation was partially compensated by continuing increased prescribing of other study analgesics as well as a significant rise in acetaminophen prescriptions (post-OSI). No changes in nonsteroidal anti-inflammatory drug prescribing were seen. A small rise in the percentage of those reporting pain but not mean pain intensity ratings continued over the study period with no changes associated with OSI. Changes in analgesic prescribing trends were not paralleled by changes in reported pain intensity for older veterans with osteoarthritis

The battle between standards: TCP/IP vs OSI victory through path dependency or by quality?

Between the end of the 1970s and 1994 a fierce competition existed between two possible standards, TCP/IP and OSI, to solve the problem of interoperability of computer networks. Around 1994 it became evident that TCP/IP and not OSI had become the dominant standard. We specifically deal with the question whether the current dominance of the TCP/IP standard is the result of third degree path dependency or of choices based on assessments of it being technical-economically superior to the OSI standard and protocols

Multimedia Teleservices Modelled with the OSI Application Layer Structure

This paper looks into the communications capabilities that are required by distributed multimedia applications to achieve relation preserving information exchange. These capabilities are derived by analyzing the notion of information exchange and are embodied in communications functionalities. To emphasize the importance of the users' view, a top-down approach is applied. The (revised) OSI Application Layer Structure (OSI-ALS) is used to model the communications functionalities and to develop an architecture for composition of multimedia services with these functionalities. This work may therefore be considered an exercise to evaluate the suitability of OSI-ALS for composition of multimedia teleservices