171 research outputs found
Response of a Living Body to 8-Tesla Magnetic Field(Crystal Growth, Chemical Reaction and Biology)
A study was made to investigate body function in high magnetic field of 8-tesla. In order to avoid magnetic-field effect on the measuring system, long distance was placed between a experimental animal and the measuring system. Changes in contractility of the heart were measured from frogs. Heart and respiratory rates were recorded from rabbits. Contractility of the heart was increased with increasing magnetic fields from 0 to 8 tesla in frogs. Heart and respiratory rates were decreased with increasing magnetic fields from 0 to 8 tesla
An Attempt to Analyze the Transformation in the Concept of the Environment during Class Practice for a Childcare Contents “Environment”
“Environmentˮ has special meanings in early childhood education and care in Japan. The present study, we identified characteristic that is a problem faced by students in understanding the concept of the environment in a class on child care in the context of the “environmentˮ in a training school for child care providers. Specifically, this study used a sentence completion test to detect the transformation in the concept of environment in the students. These data were quantitatively analyzed using text mining. In addition, we examined the transformation in the environmental concept qualitatively. As a result, the tendency to use the captured environment as a method was seen, and some characteristics became clear. Based on these findings, we considered it necessary for class improvement to be expedited
Totally Laparoscopic Gastrectomy for Gastric Cancer Associated with Recklinghausen's Disease
This paper documents the first case of gastric cancer associated with Recklinghausen's disease, which was successfully treated by a totally laparoscopic operation. A 67-year-old woman with Recklinghausen's disease was referred to this department to undergo surgical treatment for early gastric cancer. The physical examination showed multiple cutaneous neurofibromas throughout the body surface, which made an upper abdominal incision impossible. Laparoscopic surgery requiring only small incisions was well indicated, and a totally laparoscopic distal gastrectomy with lymph node dissection was performed. Billroth I reconstruction was done intra-abdominally using a delta-shaped anastomosis. The patient followed a satisfactory postoperative course with no complications. Since the totally laparoscopic gastrectomy has many advantages over open surgery, it should therefore be preferentially used as a less invasive treatment in the field of gastric cancer
A Catalogue of Morphologically Classified Galaxies from the Sloan Digital Sky Survey: North Equatorial Region
We present a catalogue of morphologically classified bright galaxies in the
north equatorial stripe (230 deg) derived from the Third Data Release of
the Sloan Digital Sky Survey (SDSS). Morphological classification is performed
by visual inspection of images in the band. The catalogue contains 2253
galaxies complete to a magnitude limit of after Galactic extinction
correction, selected from 2658 objects that are judged as extended in the
photometric catalogue in the same magnitude limit. 1866 galaxies in our
catalogue have spectroscopic information. A brief statistical analysis is
presented for the frequency of morphological types and mean colours in the
catalogue. A visual inspection of the images reveals that the rate of
interacting galaxies in the local Universe is approximately 1.5% in the
sample. A verification is made for the photometric catalogue generated
by the SDSS, especially as to its bright end completeness.Comment: Accepted for publication in Astronomical Journal. Table 2 available
at http://www.icrr.u-tokyo.ac.jp/~fukugita/MCGpaper/table2.tx
Identification of functional clock-controlled elements involved in differential timing of Per1 and Per2 transcription
It has been proposed that robust rhythmic gene expression requires clock-controlled elements (CCEs). Transcription of Per1 was reported to be regulated by the E-box and D-box in conventional reporter assays. However, such experiments are inconclusive in terms of how the CCEs and their combinations determine the phase of the Per1 gene. Whereas the phase of Per2 oscillation was found to be the most delayed among the three Period genes, the phase-delaying regions of the Per2 promoter remain to be determined. We therefore investigated the regulatory mechanism of circadian Per1 and Per2 transcription using an in vitro rhythm oscillation-monitoring system. We found that the copy number of the E-box might play an important role in determining the phase of Per1 oscillation. Based on real-time bioluminescence assays with various promoter constructs, we provide evidence that the non-canonical E-box is involved in the phase delay of Per2 oscillation. Transfection experiments confirmed that the non-canonical E-box could be activated by CLOCK/BMAL1. We also show that the D-box in the third conserved segment of the Per2 promoter generated high amplitude. Our experiments demonstrate that the copy number and various combinations of functional CCEs ultimately led to different circadian phases and amplitudes
The phase-I study of a therapeutic vaccine to ATL patients with autologous dendritic cells pulsed with peptides corresponding to Tax-specific CTL epitopes
Missing western half of the Pacific Plate: Geochemical nature of the Izanagi-Pacific Ridge interaction with a stationary boundary between the Indian and Pacific mantles
The source mantle of the basaltic ocean crust on the western half of the Pacific Plate was examined using Pb–Nd–Hf isotopes. The results showed that the subducted Izanagi–Pacific Ridge (IPR) formed from both Pacific (180–∼80 Ma) and Indian (∼80–70 Ma) mantles. The western Pacific Plate becomes younger westward and is thought to have formed from the IPR. The ridge was subducted along the Kurile–Japan–Nankai–Ryukyu (KJNR) Trench at 60–55 Ma and leading edge of the Pacific Plate is currently stagnated in the mantle transition zone. Conversely, the entire eastern half of the Pacific Plate, formed from isotopically distinct Pacific mantle along the East Pacific Rise and the Juan de Fuca Ridge, largely remains on the seafloor. The subducted IPR is inaccessible; therefore, questions regarding which mantle might be responsible for the formation of the western half of the Pacific Plate remain controversial. Knowing the source of the IPR basalts provides insight into the Indian–Pacific mantle boundary before the Cenozoic. Isotopic compositions of the basalts from borehole cores (165–130 Ma) in the western Pacific show that the surface oceanic crust is of Pacific mantle origin. However, the accreted ocean floor basalts (∼80–70 Ma) in the accretionary prism along the KJNR Trench have Indian mantle signatures. This indicates the younger western Pacific Plate of IPR origin formed partly from Indian mantle and that the Indian–Pacific mantle boundary has been stationary in the western Pacific at least since the Cretaceous
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