Il Dante di De Sanctis è ancora attuale?

My aim is to show the contemporary relevance of the work of Francesco De Sanctis, which has been intensively researched, but is now relegated to our past. However, his Dante, in contrast with his Petrarch, has timeless ethical, ideological and political qualities, while his Petrarch is still a negative example of the past and present defects of Italian. De Sanctis is still relevant in the sense that, with Dante, he favours a culture and language for ordinary people, an antidote to the diglossic situation of a ‘high’ language not only in the Renaissance but also that of the avant-garde and the technicalities of critical language. Last, but not least, the human example represented by Dante is a stronghold against the spread of what the Anglo-Polish anthropologist Bauman calls the man of “liquid modernity”

The Master athlete: An extraordinary physiological model of aging study, a delicate issue for cardiologists and sports physicians

The prolongation of average life in the industrialized countries and the definitive demonstration of preventive and therapeutic role of regular physical exercise and sport, have greatly increased the number of middle-aged and older subjects engaged in the regular practice of sports activities, not only for fun or healthy purposes, but also at competitive level. The creation by sports federations of age categories (five years in five years) has strengthened the agonistic nature of the activity. Master athletes compete not only against adversaries of the same age group but even against themselves and the Time flowing inexorably. At the scientific and clinical level, two are the fundamental implications of this phenomenon. The first is the positive effect of a regular and intense performance training, both anaerobic and aerobic power. In the latter, regular and intense training is able to slow down significantly (even 50%) the natural, progressive decline of cardiorespiratory functions observed in healthy sedentary subjects of the same age. The second, the reverse of the medal, is the difficulty encountered by sports physician and cardiologist to correctly interpret the clinical/instrumental features of the Master athlete who undergoes pre-participation screening for competitive sports. It is not always easy to differentiate the physiological, adaptive, changes of a middle-aged and older athlete from the pathological ones, related to cardiovascular disease, typical of aging, such as ischemic heart disease, arrhythmias, hypertension, valvular diseases. These difficulties can only be solved by having an adequate knowledge of the clinical and instrumental manifestations of the Master Athlete’s Heart and individual cardiopathies, and with the careful use of all modern cardiological instrumental investigations. In addition to echocardiography and maximal ECG stress-test (preferably cardio-pulmonary test), the magnetic resonance imaging with Gadolinium, and coronary tomography (TC) are playing a decisive role. [1

Tuberous sclerosis, cardiac rhabdomyomas and competitive Paralympic sports activity: a case report

We describe the case of a 20-year-old man suffering from tuberous sclerosis and an autistic disorder, already practicing swimming and athletics (running) at noncompetitive level. In the past, he was denied competitive sports due to multiple cardiac rhabdomyomas, the greatest of them slightly protruding from the septum into the left ventricle. He came to our Center for a new evaluation for competitive sport. An accurate echocardiographic and Doppler examination was substantially normal, a part of the presence of one rhabdomyoma, not causing left ventricular outflow obstruction. Furthermore, no significant arrhythmias and ECG abnormalities were observed at rest and during exercise stress test. For this reason, we decided to allow the young man to participate in competitive sports activity (Paralympic), with a close follow-up. After six years, there were no cardiovascular events and no changes in the clinical and instrumental cardiac findings

A propensity score analysis exploring the impact of adjuvant chemotherapy (aCT) in a multi-center series of resected early stage pure invasive lobular breast carcinoma (ILC)

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