28 research outputs found
Innovative Ansätze der Daseinsvorsorge in ländlichen Räumen - Lernen von Erfahrungen anderer europäischer Länder für Deutschland (InDaLE)
Das Forschungsprojekt InDaLE (Innovative Ansätze der Daseinsvorsorge in ländlichen Räumen – Lernen von Erfahrungen anderer europäischer Länder für Deutschland) untersuchte innovative Ansätze der Daseinsvorsorge in Österreich, Schweden, Schottland sowie Deutschland und prüfte deren Übertragbarkeit bzw. Anwendbarkeit auf ländliche Räume in Deutschland.
Die Broschüre enthält kompakte Projektinformationen, die wichtigsten Untersuchungsergebnisse und unsere darauf basierenden Handlungsempfehlungen
Petrarcas Trionfi in Malerei, Dichtung und Festkultur: Untersuchung zur Entstehung und Verbreitung eines florentinischen Bildmotivs auf cassoni und deschi da parto des 15. Jahrhunderts
Allegorische Triumphzüge in Malerei, Dichtung und Festkultur sind der Gegenstand dieser interdisziplinären Analyse, die den Bogen spannt von der Kunstgeschichte über die Literatur bis hin zur Theaterwissenschaft. Ausgehend von der motivgeschichtlichen Untersuchung zur Entstehung und Verbreitung eines florentinischen Bildmotivs auf cassoni und deschi da parto des 15. Jahrhunderts, gelingt es der Autorin, zu zeigen, daß die Entstehungsgeschichte dieser Bildmotive nicht allein kunsthistorisch zu fassen ist, sondern erst durch literarisch-philosophische und sozio-kulturelle Komponenten erklärt werden
Die Ermittlung eines fairen Preises fĂĽr risikobehaftete Anlagen
Alexandra OrtnerKlagenfurt, Alpen-Adria-Univ., Dipl.-Arb., 2012(VLID)241174
Policies for affordable rentals in Germany and Sweden – how do housing policies get implemented in planning and realised in growing cities?
Book of proceedings: Annual AESOP Congress, Spaces of Dialog for Places of Dignity, Lisbon, 11-14th July, 2017Cities with a growing population are faced with the challenge to offer sufficient and adequate living space to all income groups. Those with medium to high incomes and a certain financial flexibility have of course bigger prospects to choose from a wider range of available housing offers within the cities. In contrast, for inhabitants with low to medium incomes, it’s getting increasingly complicated to have access to affordable rentals, since the increasing demand for housing, e.g. because of the raise of single households, leads to rising prices and to a shortage of low-cost rental apartments. Further, increasing income differences and a large influx of refugees put extra pressure on the sector. That trend is well known to decision makers in housing policy in almost all European countries. In order to develop appropriate housing conditions for all inhabitants and to ensure equal living space conditions, housing policies are formulated on federal and state level. For instance, suppliers as well as demanders of rental apartments get support by financial subsidies like housing benefits or tax amortisations. Furthermore, the cities are requested to implement housing policies into their urban residential planning documents.Published versio
Gating Properties of Cav1.3 Calcium Channels: Insight from Alternative Splicing and Human Mutations
Multiple Symmetric Lipomatosis: A Cross-Sectional Study to Investigate Clinical Features and Patients’ Quality of Life
Within the subcutaneous adipose tissue diseases, multiple symmetric lipomatosis (MSL) (syn.: Launois Bensaude Syndrome, Morbus Madelung, benign symmetric lipomatosis) is rare. The pathogenesis of MSL remains unclear. We investigated the largest German cohort of MSL patients to obtain anamnestic data and quality of life with a standard questionnaire. Twenty-nine patients with confirmed MSL were included and filled in a questionnaire designed for this study. The questionnaire assessed common anamnestic factors, such as quality of life (EQ-5D-3L) and subjective treatment goals and success (“Patient-Benefit-Index-Lymphedema”, PBI-L). The gender distribution of the patients involved in the study was m/f: 1/4 (male: n = 6 (21%); female n = 23 (79%)). While the exact pathophysiology of MSL remains unclear, a subset of patients’ positive family history suggests a strong genetic factor, sometimes compatible with autosomal dominant inheritance. Patients with MSL showed lower health states (EQ VAS Score: m = 51, sd = 24, range = 0–90) than the German norm population (m = 77). Around two thirds (68%) of patients reported relevant benefits of therapy (liposuction/lipectomy). In our cohort about one third of the patients reported a positive family history for MSL-like features. Additionally, at least in some patients, a strong genetic factor, compatible with autosomal dominant inheritance, seems a possible major driver of MSL development. Alcohol consumption and MSL development has to be regarded as a controversial issue. Patients suffering from MSL have a clear decrease in quality of life and a marked wish for treatment
Creation and characterization of free-standing cryogenic targets for laser-driven ion acceleration
A technique for the creation of free-standing cryogenic targets for laser-driven ion acceleration is presented, which allows us to create solid state targets consisting of initially gaseous materials. In particular, the use of deuterium and the methods for its preparation as a target material for laser-driven ion acceleration are discussed. Moving in the phase diagram through the liquid phase leads to the substance covering an aperture on a cooled copper frame where it is solidified through further cooling. An account of characterization techniques for target thickness is given, with a focus on deducing thickness values from distance values delivered by chromatic confocal sensors
Adipose Tissue in Multiple Symmetric Lipomatosis Shows Features of Brown/Beige Fat
Introduction
Multiple symmetric lipomatosis (MSL) (syn.: Launois–Bensaude Syndrome, benign symmetric lipomatosis) is a rare disease of fatty tissue. The pathophysiology of MSL still remains unclear, although several approaches have been described in order to understand it. Beside morphological characteristics and some molecular cell biological approaches, little is known about the histological and immunohistochemical characterization of adipose tissue from patients with MSL.
Methods
From the 45 patients with MSL in our database, 10 were included in the study. Fat tissue samples were collected from affected and unaffected areas. The forearm served as a control area as this area is not affected in MSL. The specimens were analyzed after selected stainings were taken (hematoxylin–eosin = HE, Elastica van Gieson, Ladewig, CD200, CIDEA, myf5, p107, Prdm16, Sca-1, syndecan, UCP1, MAC387, Glut4).
Results
In patients suffering from MSL, no macroscopic or microscopic morphological difference could be found between affected and unaffected adipose tissue in HE stainings. The majority of samples showed positivity for UCP1 (9/10 clinically affected tissues, 7/10 clinically unaffected tissues) and CD200.
Conclusion
Marker profiles support the hypothesis that affected adipose tissue derives from brown or beige adipose tissue rather than from white fat.
Level of Evidence IV
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