187 research outputs found
Integrated Solid Oxide Fuel Cell Power System Characteristics Prediction
The main objective of this paper is to deduce the specific characteristics of the CHP 100kWe Solid Oxide Fuel Cell (SOFC) Power System from the steady state experimental data. From the experimental data, the authors have been developed and validated the steady state mathematical model. From the control room the steady state experimental data of the SOFC power conditioning are available and using the developed steady state mathematical model, the authors have been obtained the characteristic curves of the system performed by Siemens-Westinghouse Power Corporation. As a methodology the backward and forward power flow analysis has been employed. The backward power flow makes possible to obtain the SOFC power system operating point at different load levels, resulting as the load characteristic. By knowing the fuel cell output characteristic, the forward power flow analysis is used to predict the power system efficiency in different operating points, to choose the adequate control decision in order to obtain the high efficiency operation of the SOFC power system at different load levels. The CHP 100kWe power system is located at Gas Turbine Technologies Company (a Siemens Subsidiary), TurboCare brand in Turin, Italy. The work was carried out through the Energia da Ossidi Solidi (EOS) Project. The SOFC stack delivers constant power permanently in order to supply the electric and thermal power both to the TurboCare Company and to the national grid
Franco-American Salem Oral History: Roger L\u27Heureux
https://digitalcommons.salemstate.edu/fahc/1011/thumbnail.jp
Franco-American Salem Oral History: Georgette Pied
https://digitalcommons.salemstate.edu/fahc/1002/thumbnail.jp
Franco-American Salem Oral History: Armand Devoe
https://digitalcommons.salemstate.edu/fahc/1000/thumbnail.jp
A History of Saint Joseph’s Parish in Salem, Massachusetts: 1873-1948
This volume focuses attention on the centrality of St. Joseph’s parish (the people as well as the structures) in shaping, sustaining and celebrating the spiritual, cultural and linguistic life of French-Canadians and their descendants. Over seven decades, the parish grew in size and import, providing bilingual and classical education in its schools, organizing and launching social organizations, financial institutions and cultural events to assist its members with life in the United States, and offering a rich religious experience that helped generations of French-Canadian families maintain cultural, faith and linguistic connections to their ancestral homes. Written in 1948, on the occasion of the parish’s seventy-fifth anniversary, the authors not only trace the growth and transformation of St. Joseph’s but offer a close accounting of the place of the parish and its parishioners in the civic, economic and ecclesiastical life of the city, the region, the Commonwealth and even the global church.
Originally published Published by the Laurier Association, 1948
Translated from French by Dr. Elizabeth Blood, Salem State University
Edited with an Introduction by Dr. Elizabeth Duclos-Orsello, Salem State Universityhttps://digitalcommons.salemstate.edu/fchc/1001/thumbnail.jp
Franco-American Salem Oral History: Diane Charette
https://digitalcommons.salemstate.edu/fahc/1001/thumbnail.jp
New endoscopic over-the-scope clip system for treatment of a chronic post-surgical tracheoesophageal fistula
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Binding cooperativity of membrane adhesion receptors
The adhesion of cells is mediated by receptors and ligands anchored in
apposing membranes. A central question is how to characterize the binding
affinity of these membrane-anchored molecules. For soluble molecules, the
binding affinity is typically quantified by the binding equilibrium constant
K3D in the linear relation [RL] = K3D [R][L] between the volume concentration
[RL] of bound complexes and the volume concentrations [R] and [L] of unbound
molecules. For membrane-anchored molecules, it is often assumed by analogy that
the area concentration of bound complexes [RL] is proportional to the product
[R][L] of the area concentrations for the unbound receptor and ligand
molecules. We show here (i) that this analogy is only valid for two planar
membranes immobilized on rigid surfaces, and (ii) that the thermal roughness of
flexible membranes leads to cooperative binding of receptors and ligands. In
the case of flexible membranes, the area concentration [RL] of receptor-ligand
bonds is proportional to the square of [R][L] for typical lengths and
concentrations of receptors and ligands in cell adhesion zones. The cooperative
binding helps to understand why different experimental methods for measuring
the binding affinity of membrane-anchored molecules have led to values
differing by several orders of magnitude.Comment: 9 pages, 4 figures; to appear in Soft Matte
Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse
Receptor-ligand couples in the cell-cell contact interface between a T cell and an antigen-presenting cell form distinct geometric patterns and undergo spatial rearrangement within the contact interface. Spatial segregation of the antigen and adhesion receptors occurs within seconds of contact, central aggregation of the antigen receptor then occurring over 1-5 min. This structure, called the immunological synapse, is becoming a paradigm for localized signaling. However, the mechanisms driving its formation, in particular spatial segregation, are currently not understood. With a reaction diffusion model incorporating thermodynamics, elasticity, and reaction kinetics, we examine the hypothesis that differing bond lengths (extracellular domain size) is the driving force behind molecular segregation. We derive two key conditions necessary for segregation: a thermodynamic criterion on the effective bond elasticity and a requirement for the seeding/nucleation of domains. Domains have a minimum length scale and will only spontaneously coalesce/aggregate if the contact area is small or the membrane relaxation distance large. Otherwise, differential attachment of receptors to the cytoskeleton is required for central aggregation. Our analysis indicates that differential bond lengths have a significant effect on synapse dynamics, i.e., there is a significant contribution to the free energy of the interaction, suggesting that segregation by differential bond length is important in cell-cell contact interfaces and the immunological synapse
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