308 research outputs found
Convection-reaction equation based magnetic resonance electrical properties tomography (cr-MREPT)
Cataloged from PDF version of article.Images of electrical conductivity and permittivity
of tissues may be used for diagnostic purposes as well as for
estimating local specific absorption rate distributions. Magnetic
resonance electrical properties tomography (MREPT) aims at
noninvasively obtaining conductivity and permittivity images
at radio-frequency frequencies of magnetic resonance imaging
systems. MREPT algorithms are based on measuring the B1 field
which is perturbed by the electrical properties of the imaged
object. In this study, the relation between the electrical properties
and the measured B1 field is formulated for the first time as a
well-known convection-reaction equation. The suggested novel
algorithm, called âcr-MREPT,â is based on the solution of this
equation on a triangular mesh, and in contrast to previously
proposed algorithms, it is applicable in practice not only for
regions where electrical properties are relatively constant but also
for regions where they vary. The convective field of the convection-reaction
equation depends on the spatial derivatives of the
B1 field, and in the regions where its magnitude is low, a spot-like
artifact is observed in the reconstructed electrical properties
images. For eliminating this artifact, two different methods are
developed, namely âconstrained cr-MREPTâ and âdouble-excitation
cr-MREPT.â Successful reconstructions are obtained using
noisy and noise-free simulated data, and experimental data from
phantoms
Thermonuclear Supernovae: Simulations of the Deflagration Stage and Their Implications
Large-scale three-dimensional numerical simulations of the deflagration stage
of a thermonuclear supernova explosion show the formation and evolution of a
highly convoluted turbulent flame in a gravitational field of an expanding
carbon-oxygen white dwarf. The flame dynamics is dominated by the
gravity-induced Rayleigh-Taylor instability that controls the burning rate. The
thermonuclear deflagration releases enough energy to produce a healthy
explosion. The turbulent flame, however, leaves large amounts of unburnt and
partially burnt material near the star center, whereas observations imply these
materials only in outer layers. This disagreement could be resolved if the
deflagration triggers a detonation.Comment: 17 pages, 5 figures. To appear in Science, January 200
Structural, Electronic, and Magnetic Properties of LaNiâ ââTâ (T = Fe, Mn) Compounds
Structures and magnetic properties of the LaNi5-xFex and LaNi5-xMnx compounds have been investigated using neutron diffraction and first-principles tight-binding-linear-muffin-tin-orbital methods. Both neutron diffraction refinement data and total energy calculations show that the Fe and Mn atoms preferentially occupy the 3g sites in the hexagonal CaCu5-type structure. The calculated magnetic moments of Fe and Ni atoms are of 2.4-2.5ÎŒB and 0.2-0.5ÎŒB in LaNi5-xFex, respectively. The magnetic structure exhibits more localized moments at Fe atoms in LaNi5-xFex when x †1.0. Electronic structure calculations indicate that s-conduction electron spin polarization from the Ni or La atoms strongly interacts with Fe(Mn) d-spin moments in LaNi5-xFe(Mn)x (x â 0) compounds, which gives rise to a very large valence transferred hyperfine field on the Ni or La sites. This s-d hybridization may lead to an interaction among magnetic clusters in these kinds of materials and may cause a spin freezing effect at low temperature when the Fe(Mn) content is very low in LaNi5-xFe(Mn)x. Mn atoms show magnetic moments of 3.0ÎŒB per atom due to a large exchange splitting in LaNi5-xMnx (x â 0). LaNi4Mn is found to be ferrimagnetic, whereas antiferromagnetic exchange coupling between the Mn atoms is preferred for LaNi3Mn2. Both ferrimagnetic and ferromagnetic exchange interactions between Mn atoms are found in the LaNi2Mn3 compounds. The calculated results are in good agreement with the experimental neutron data
Spontaneous Transition of Turbulent Flames to Detonations in Unconfined Media
Deflagration-to-detonation transition (DDT) can occur in environments ranging
from experimental and industrial systems to astrophysical thermonuclear (type
Ia) supernovae explosions. Substantial progress has been made in explaining the
nature of DDT in confined systems with walls, internal obstacles, or
pre-existing shocks. It remains unclear, however, whether DDT can occur in
unconfined media. Here we use direct numerical simulations (DNS) to show that
for high enough turbulent intensities unconfined, subsonic, premixed, turbulent
flames are inherently unstable to DDT. The associated mechanism, based on the
nonsteady evolution of flames faster than the Chapman-Jouguet deflagrations, is
qualitatively different from the traditionally suggested spontaneous reaction
wave model, and thus does not require the formation of distributed flames.
Critical turbulent flame speeds, predicted by this mechanism for the onset of
DDT, are in agreement with DNS results.Comment: 4 pages, 3 figures; accepted to Physical Review Letter
Statistical modeling of health space based on metabolic stress and oxidative stress scores
Abstract
Background
Health space (HS) is a statistical way of visualizing individuals health status in multi-dimensional space. In this study, we propose a novel HS in two-dimensional space based on scores of metabolic stress and of oxidative stress.
Methods
These scores were derived from three statistical models: logistic regression model, logistic mixed effect model, and proportional odds model. HSs were developed using Korea National Health And Nutrition Examination Survey data with 32,140 samples. To evaluate and compare the performance of the HSs, we also developed the Health Space Index (HSI) which is a quantitative performance measure based on the approximate 95% confidence ellipses of HS.
Results
Through simulation studies, we confirmed that HS from the proportional odds model showed highest power in discriminating health status of individual (subject). Further validation studies were conducted using two independent cohort datasets: a health examination dataset from Ewha-Boramae cohort with 862 samples and a population-based cohort from the Korea association resource project with 3,199 samples.
Conclusions
These validation studies using two independent datasets successfully demonstrated the usefulness of the proposed HS
Micro-Electro-Mechanical-Systems (MEMS) and Fluid Flows
The micromachining technology that emerged in the late 1980s can provide micron-sized sensors and actuators. These micro transducers are able to be integrated with signal conditioning and processing circuitry to form micro-electro-mechanical-systems (MEMS) that can perform real-time distributed control. This capability opens up a new territory for flow control research. On the other hand, surface effects dominate the fluid flowing through these miniature mechanical devices because of the large surface-to-volume ratio in micron-scale configurations. We need to reexamine the surface forces in the momentum equation. Owing to their smallness, gas flows experience large Knudsen numbers, and therefore boundary conditions need to be modified. Besides being an enabling technology, MEMS also provide many challenges for fundamental flow-science research
Implication of backward contact tracing in the presence of overdispersed transmission in COVID-19 outbreaks
Introduction: Contact tracing has the potential to control outbreaks without the need for stringent physical distancing policies, e.g. civil lockdowns. Unlike forward contact tracing, backward contact tracing identifies the source of newly detected cases. This approach is particularly valuable when there is high individual-level variation in the number of secondary transmissions (overdispersion). Methods: By using a simple branching process model, we explored the potential of combining backward contact tracing with more conventional forward contact tracing for control of COVID-19. We estimated the typical size of clusters that can be reached by backward tracing and simulated the incremental effectiveness of combining backward tracing with conventional forward tracing. Results: Across ranges of parameter values consistent with dynamics of SARS-CoV-2, backward tracing is expected to identify a primary case generating 3-10 times more infections than a randomly chosen case, typically increasing the proportion of subsequent cases averted by a factor of 2-3. The estimated number of cases averted by backward tracing became greater with a higher degree of overdispersion. Conclusion: Backward contact tracing can be an effective tool for outbreak control, especially in the presence of overdispersion as is observed with SARS-CoV-2
Origins of the Ambient Solar Wind: Implications for Space Weather
The Sun's outer atmosphere is heated to temperatures of millions of degrees,
and solar plasma flows out into interplanetary space at supersonic speeds. This
paper reviews our current understanding of these interrelated problems: coronal
heating and the acceleration of the ambient solar wind. We also discuss where
the community stands in its ability to forecast how variations in the solar
wind (i.e., fast and slow wind streams) impact the Earth. Although the last few
decades have seen significant progress in observations and modeling, we still
do not have a complete understanding of the relevant physical processes, nor do
we have a quantitatively precise census of which coronal structures contribute
to specific types of solar wind. Fast streams are known to be connected to the
central regions of large coronal holes. Slow streams, however, appear to come
from a wide range of sources, including streamers, pseudostreamers, coronal
loops, active regions, and coronal hole boundaries. Complicating our
understanding even more is the fact that processes such as turbulence,
stream-stream interactions, and Coulomb collisions can make it difficult to
unambiguously map a parcel measured at 1 AU back down to its coronal source. We
also review recent progress -- in theoretical modeling, observational data
analysis, and forecasting techniques that sit at the interface between data and
theory -- that gives us hope that the above problems are indeed solvable.Comment: Accepted for publication in Space Science Reviews. Special issue
connected with a 2016 ISSI workshop on "The Scientific Foundations of Space
Weather." 44 pages, 9 figure
Standing waves for acoustic levitation
Standing waves are the most popular method to achieve acoustic trapping. Particles with greater acoustic impedance than the propagation medium will be trapped at the pressure nodes of a standing wave. Acoustic trapping can be used to hold particles of various materials and sizes, without the need of a close-loop controlling system. Acoustic levitation is a helpful and versatile tool for biomaterials and chemistry, with applications in spectroscopy and lab-on-a-droplet procedures. In this chapter, multiple methods are presented to simulate the acoustic field generated by one or multiple emitters. From the acoustic field, models such as the Gor'kov potential or the Flux Integral are applied to calculate the force exerted on the levitated particles. The position and angle of the acoustic emitters play a fundamental role, thus we analyse commonly used configurations such as emitter and reflector, two opposed emitters, or arrangements using phased arrays
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