375 research outputs found
Emotional Awareness During Bug Fixes – A Pilot Study
This study examines the effects of a programmer\u27s emotional awareness on progress while fixing bugs. The goal of the study is to capitalize on emotional awareness to ultimately increase progress made during software development. This process could result in improved software maintenance
Convection-reaction equation based magnetic resonance electrical properties tomography (cr-MREPT)
Cataloged from PDF version of article.Images of electrical conductivity and permittivity
of tissues may be used for diagnostic purposes as well as for
estimating local specific absorption rate distributions. Magnetic
resonance electrical properties tomography (MREPT) aims at
noninvasively obtaining conductivity and permittivity images
at radio-frequency frequencies of magnetic resonance imaging
systems. MREPT algorithms are based on measuring the B1 field
which is perturbed by the electrical properties of the imaged
object. In this study, the relation between the electrical properties
and the measured B1 field is formulated for the first time as a
well-known convection-reaction equation. The suggested novel
algorithm, called “cr-MREPT,” is based on the solution of this
equation on a triangular mesh, and in contrast to previously
proposed algorithms, it is applicable in practice not only for
regions where electrical properties are relatively constant but also
for regions where they vary. The convective field of the convection-reaction
equation depends on the spatial derivatives of the
B1 field, and in the regions where its magnitude is low, a spot-like
artifact is observed in the reconstructed electrical properties
images. For eliminating this artifact, two different methods are
developed, namely “constrained cr-MREPT” and “double-excitation
cr-MREPT.” Successful reconstructions are obtained using
noisy and noise-free simulated data, and experimental data from
phantoms
Emotional Awareness During Bug Fixes – A Pilot Study
This study examines the effects of a programmer\u27s emotional awareness on progress while fixing bugs. The goal of the study is to capitalize on emotional awareness to ultimately increase progress made during software development. This process could result in improved software maintenance
Thermonuclear Supernovae: Simulations of the Deflagration Stage and Their Implications
Large-scale three-dimensional numerical simulations of the deflagration stage
of a thermonuclear supernova explosion show the formation and evolution of a
highly convoluted turbulent flame in a gravitational field of an expanding
carbon-oxygen white dwarf. The flame dynamics is dominated by the
gravity-induced Rayleigh-Taylor instability that controls the burning rate. The
thermonuclear deflagration releases enough energy to produce a healthy
explosion. The turbulent flame, however, leaves large amounts of unburnt and
partially burnt material near the star center, whereas observations imply these
materials only in outer layers. This disagreement could be resolved if the
deflagration triggers a detonation.Comment: 17 pages, 5 figures. To appear in Science, January 200
Subchondral osteopenia and accelerated bone remodelling post-ovariectomy - a possible mechanism for subchondral microfractures in the aetiology of spontaneous osteonecrosis of the knee?
Osteopenia and subchondral microfractures are implicated in the aetiology of spontaneous osteonecrosis of the knee. The ovine tibia shows significant alterations of the trabecular architecture within the subchondral bone of the medial tibial plateau post-ovariectomy, including reduced trabecular bone volume fraction. We hypothesise that accelerated subchondral bone resorption may also play a role in increasing microfracture risk at this site. 23 sheep were examined in this study; 10 of the sheep underwent ovariectomy (OVX), while the remainder (n=13) were kept as controls (CON). Five fluorochrome dyes were administered intravenously at 12 week intervals via the jugular vein to both groups, to label sites of bone turnover. These animals were then sacrificed at 12 months post-operatively. Bone turnover was significantly increased in the OVX group in both trabecular bone (2.024 vs. 1.047, p = 0.05) and within the subchondral bone plate (4.68 vs. 0.69 # / mm2; p \u3c 0.001). In addition to the classically-described turnover visible along trabecular surfaces, we also found visual evidence of intra-trabecular osteonal remodelling. In conclusion, this study shows significant alterations in bone turnover in both trabecular bone and within the subchondral bone plate at one-year post-ovariectomy. Remodelling of trabecular bone was due to both classically described hemi-osteonal and intra-trabecular osteonal remodelling. The presence of both localised osteopenia and accelerated bone remodelling within the medial tibial plateau provide a possible mechanism for subchondral microfractures in the aetiology of spontaneous osteonecrosis of the knee. Further utilisation of the ovariectomised ewe may be useful for further study in this field
Fourier transform magnetic resonance current density imaging (FT-MRCDI) from one component of magnetic flux density
Fourier transform (FT)-based algorithms for magnetic resonance current density imaging (MRCDI) from one component of magnetic flux density have been developed for 2D and 3D problems. For 2D problems, where current is confined to the xy-plane and z-component of the magnetic flux density is measured also on the xy-plane inside the object, an iterative FT-MRCDI algorithm is developed by which both the current distribution inside the object and the z-component of the magnetic flux density on the xy-plane outside the object are reconstructed. The method is applied to simulated as well as actual data from phantoms. The effect of measurement error on the spatial resolution of the current density reconstruction is also investigated. For 3D objects an iterative FT-based algorithm is developed whereby the projected current is reconstructed on any slice using as data the Laplacian of the z-component of magnetic flux density measured for that slice. In an injected current MRCDI scenario, the current is not divergence free on the boundary of the object. The method developed in this study also handles this situation. © 2010 Institute of Physics and Engineering in Medicine
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