DEVELOPMENT OF A CONTINUOUS NANOPARTICLE COATING WITH ELECTROSPRAYING

Coating of micron-sized particles (host particles) with nanoparticles can result in modifying the surface properties of host particles leading to various applications. This work presents a novel concept of combining the electrospraying of nanoparticles onto the charged particles entrained out of the fluidized bed for developing a continuous coating process. By controlling the processes to effectively charge and contact particles using electric forces, we are able to fine-tune the properties of the obtained nano-coated particles

Recommendations for future research in relation to pediatric pulmonary embolism: communication from the SSC of the ISTH

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142464/1/jth13902_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142464/2/jth13902.pd

Apixaban overdose in children: case report and proposed management. A brief communication from the Pediatric and Neonatal Thrombosis and Hemostasis SSC of ISTH

\ua9 2024 The Authors. Background: Direct oral anticoagulants are commonly prescribed for adults and increasingly also for children requiring anticoagulation therapy. While household medications should not be accessible to children, accidental, and intentional overdoses occur. Key Clinical Question: How should apixaban overdose in children be managed?. Clinical Approach: We present a case of an accidental overdose with the factor Xa antagonist apixaban in a young child and propose an approach to the management of cases of apixaban overdose in children. Conclusion: Given the increasing use of direct oral anticoagulants, it is important to have an approach to the management of overdose of these medications

A powerful and rapid approach to human genome scanning in small quantities of genomic DNA

Dense maps of short-tandem-repeat polymorphisms (STRPs) have allowed genome-wide searches for genes involved in a great variety of diseases with genetic influences, including common complex diseases. Generally for this purpose, marker sets with a 10 cM spacing are genotyped in hundreds of individuals. We have performed power simulations to estimate the maximum possible intermarker distance that still allows for sufficient power. In this paper we further report on modifications of previously published protocols, resulting in a powerful screening set containing 229 STRPs with an average spacing of 18·3 cM. A complete genome scan using our protocol requires only 80 multiplex PCR reactions which are all carried out using one set of conditions and which do not contain overlapping marker allele sizes. The multiplex PCR reactions are grouped by sets of chromosomes, which enables on-line statistical analysis of a set of chromosomes, as sets of chromosomes are being genotyped. A genome scan following this modified protocol can be performed using a maximum amount of 2.5 μg of genomic DNA per individual, isolated from either blood or from mouth swabs.link_to_subscribed_fulltex

Circular Polarization in Pulsar Integrated Profiles: Updates

We update the systematic studies of circular polarization in integrated pulse profiles by Han et al (1998). Data of circular polarization profiles are compiled. Sense reversals can occur in core or cone components, or near the intersection between components. The correlation between the sense of circular polarization and the sense of position angle variation for conal-double pulsars is confirmed with a much large database. Circular polarization of some pulsars has clear changes with frequency. Circular polarization of millisecond pulsars is marginally different from that of normal pulsars.Comment: 10 pages, 6 figures, accepted and will be published soon by Chinese Journal of Astronomy and Astrophysics (ChJAA

Rotation measure variations for 20 millisecond pulsars

We report on variations in the mean position angle of the 20 millisecond pulsars being observed as part of the Parkes Pulsar Timing Array (PPTA) project. It is found that the observed variations are dominated by changes in the Faraday rotation occurring in the Earth's ionosphere. Two ionospheric models are used to correct for the ionospheric contribution and it is found that one based on the International Reference Ionosphere gave the best results. Little or no significant long-term variation in interstellar RM was found with limits typically about 0.1 rad m$^{-2}$ yr$^{-1}$ in absolute value. In a few cases, apparently significant RM variations over timescales of a few 100 days or more were seen. These are unlikely to be due to localised magnetised regions crossing the line of sight since the implied magnetic fields are too high. Most probably they are statistical fluctuations due to random spatial and temporal variations in the interstellar electron density and magnetic field along the line of sight.Comment: Accepted for publication in Astrophysics & Space Scienc

Pulsar rotation measures and the magnetic structure of our Galaxy

We have obtained 63 rotation measures (RMs) from polarization observations of southern pulsars, of which 54 are new measurements and 3 are varied from previous values. The new pulsar RM data at high Galactic latitudes are mostly consistent with the antisymmetric RM distribution found previously. For the Galactic disc, evidence for a field reversal near the Perseus arm, and possibly another beyond it, is presented. Inside the Solar Circle, in addition to the two known field reversals in or near the Carina-Sagittartus arm and the Crux-Scutum arm, a further reversal in the Norma arm is tentatively identified. These reversals, together with the pitch angle derived from pulsar RM and stellar polarization distributions, are consistent with bisymmetric spiral (BSS) models for the large-scale magnetic field structure in the disc of our Galaxy. However, discrimination between models is complicated by the presence of smaller-scale irregularities in the magnetic field, as well as uncertainties in the theoretical modelling.Comment: 10pages; 8 figures; Accepted by MNRA