8 research outputs found
High-Resolution Patterned Cellular Constructs by Droplet-Based 3D Printing
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/08/2017
- Field of study
AbstractBioprinting is an emerging technique for the fabrication of living tissues that allows cells to be arranged in predetermined three-dimensional (3D) architectures. However, to date, there are limited examples of bioprinted constructs containing multiple cell types patterned at high-resolution. Here we present a low-cost process that employs 3D printing of aqueous droplets containing mammalian cells to produce robust, patterned constructs in oil, which were reproducibly transferred to culture medium. Human embryonic kidney (HEK) cells and ovine mesenchymal stem cells (oMSCs) were printed at tissue-relevant densities (107 cells mL−1) and a high droplet resolution of 1 nL. High-resolution 3D geometries were printed with features of ≤200 μm; these included an arborised cell junction, a diagonal-plane junction and an osteochondral interface. The printed cells showed high viability (90% on average) and HEK cells within the printed structures were shown to proliferate under culture conditions. Significantly, a five-week tissue engineering study demonstrated that printed oMSCs could be differentiated down the chondrogenic lineage to generate cartilage-like structures containing type II collagen.</jats:p
Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial
- Author
- Abdel-Rahman Emaad
- Abhayaratna Walter
- Abramof Ness Rosane
- Acosta Idalia
- Adams Atoya
- Adawi Faiad
- Adler Sharon
- Ahmed Fayzal
- Aizenberg Diego
- Ajani Dilawar
- Al-Karadsheh Amer
- Albota Adrian
- Alferi Dino
- Alicic Radica
- Alla Sreedhara
- Allison D
- Almeida Edgar
- Alpizar Salazar Melchor
- Amer Joseph
- Amod Aslam
- Andrawis Nabil
- Antonio Bossi Carlo
- Antsiferov Mikhail
- Antunes Daniela
- Araki Hideo
- Arango Clara
- Arcos Edgar
- Arif Ahmed
- Arif Imrozia
- Arkhipov Mikhail
- Armaly Zaher
- Aroca Gustavo
- Asprusten Emil
- Atar Shaul
- Avila Pardo Sandro
- Awad Ahmed
- Axthelm Christoph
- Azizad Masoud
- Azizah Aziz Nor
- B Brouwer C
- Babikova Jana
- Babkin Andrey
- Badak Ozer
- Bahrami Michael
- Bajcsi Dora
- Baker John
- Bala Cornelia
- Ballesteros Rosa
- Bansal Shweta
- Barag Steven
- Barakzoy Ahmad
- Baranov Vitaliy
- Barbarash Olga
- Barbonta Hortensia
- Barney Mark
- Barre Paul
- Barrera Sandra
- Barreto Carlos
- Barreto Germ\ue1n
- Bartolacci In\ue9s
- Bashir Khalid
- Bashkin Amir
- Bastidas Adrian Miriam
- Bautista Albert
- Bautista Jose
- Bech Jesper
- Beddhu Srinivasan
- Beltr\ue1n L\uf3pez Nelly
- Ben Chetrit Sydney
- Benitez Diego
- Benjamin Sabrina
- Berar Yanay Noa
- Berenji Ramin
- Bertram Pitt
- Bertsch John
- Besada Diego
- Bhana Sindeep
- Bhargava Anuj
- Bilz Stefan
- Birkenfeld Andreas
- Birriel Jose
- Bittar Julio
- Blanco Guillermo
- Bleich David
- Boletis Ioannis
- Bondarets Iryna
- Bonora Enzo
- Bornfreund Jonathan
- Boshnyashka Radostina
- Botelho Roberto
- Botero Rodrigo
- Botsyurko Volodymyr
- Bouarich Hanane
- Brada Michal
- Brandao Ilidio
- Brar Harjeet
- Braun Hermann
- Brezina Jiri
- Brian Susan
- Brietzke Stephen
- Brito Claudia
- Bruchfeld Annette
- Bruno Giorda Carlo
- Brusco Osvaldo
- Bu Ruifang
- Bucek Petr
- Buganova Ingrid
- Burgner Anna
- Busch Klaus
- Busch Robert
- Butrymowicz Patrycja
- C Bakker R
- C\ue1rdenas Tatiana
- Caceaune Elena
- Cai Hanqing
- Calabr\uf2 Paolo
- Calero Francesca
- Canadas Rafael
- Canani Luis
- Caramori Maria
- Cardona Jose
- Cariou Bertrand
- Carlo Maggi Davide
- Carlos Palma Juan
- Carlos Prieto Juan
- Carlson Brian
- Carpio Jose
- Carvalho Rui
- Case Christopher
- Castro Cristina
- Catindig Elizabeth
- Catrinoiu Doina
- Cayli Murat
- Cereto Castro Fernando
- Cerqueira Maria
- Chahin Mariano
- Chang Chiz-Tzung
- Chantrel Fran\ue7ois
- Chen Dejun
- Chen Nan
- Chen Qinkai
- Cheng Jinluo
- Chernikova Viktoriia
- Chernin Gil
- Chernyavskaya Elena
- Chew Wong Alfredo
- Christina Nowack
- Chuang Lee-Ming
- Chung ChoonHee
- Ciechanowski Kazimierz
- Cieslik Grazyna
- Cigarr\ue1n Guldris Secundino
- Cimino Roberto
- Clavel Sylvaine
- Clodi Martin
- Cobos Jorge
- Colman Peter
- Colquhoun David
- Constantin Ciprian
- Contzen Christel
- Conway James
- Coronel Julian
- Cortes-Maisonet Gregorio
- Cortes-Maisonet Gregorio
- Cournoyer Serge
- Crawford Veronica
- Cristina Gregorini Maria
- Cruz Humberto
- Cruzado Garrit Josep
- Cure Carlos
- Curiac Dan
- Cutfield Rick
- Dandillaya Ramprasad
- Dang Cuong
- Danos Peter
- Darawsha Mahmud
- de \uc1lvaro Fernando
- de Paula Rogerio
- Deerochanawong Chaicharn
- Degenhardt Stefan
- Demko Arkadiy
- Derwahl Karl
- Dhanireddy Soni
- Din Zia
- Distiller Larry
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- Dolores Mart\uednez Esteban M\uaa
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- Dong Junwu
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- Drexel Heinz
- Du Yuming
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- E Costa Fernando Teixeira
- Ebenbichler Christoph
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- Eliasson Ken
- Emdin Michele
- Engelen Wendy
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- Frank Malin
- Frias Juan
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- Vega Damaris
- Velaviciene Audrone
- Vencio Sergio
- Verges Bruno
- Verlan Nadezhda
- Vi\uf1es Gloria
- Vijayaraman Arutchelvam
- Vila Lobos Ana
- Villagordoa Mesa Juan
- Villegas Iv\ue1n
- Vitou Louise
- Vlad Adrian
- Vlasenko Maryna
- Vorokhobina Natalya
- Wainstein Julio
- Wainstein Julio
- Walsh Michael
- Wan Ronald Ma Ching
- Wang Hao
- Wang Jianqin
- Wang Li
- Wang Lihua
- Wang Xinjun
- Wanner Christoph
- Wasilewska Katarzyna
- Wassermann Alfredo
- Wei Jiali
- Weisnagel Stanley
- Weissman Peter
- Whaley-Connell Adam
- Wierusz-Wysocka Bogna
- Wilderman Igor
- Winston Jonathan
- Wise Jonathan
- Wittert Gary
- Wnetrzak-Michalska Renata
- Wong Yuk-Ki
- Wu Chaoqing
- Wu Mai-Szu
- Wu Ming-Ju
- Wu Tianfeng
- Wudi Krisztina
- Wuerzner Gregoire
- Wynne Katie-Jane
- Xing Changying
- Xiong Fei
- Xu Ning
- Xu Xudong
- Yagil Yoram
- Yajima Ken
- Yakhontov Davyd
- Yale Jean-Francois
- Yamada Daishiro
- Yamada Masayo
- Yamagata Kazuo
- Yamakawa Fumiko
- Yamakawa Ken
- Yamasaki Yoshimitsu
- Yambe Yuko
- Yanai Hidekatsu
- Yang Jinkui
- Yasuda Tetsuyuki
- Yenicerioglu Yavuz
- Yeung Vincent
- Yilmaz Huseyin
- Yin Aiping
- Yoncheva-Mihaylova Mariana
- Young Park Cheol
- Yuan Lee Li
- Yupanqui Hern\ue1n
- Yuryev Michael
- Zakharova Elena
- Zalevskaya Alsu
- Zanozina Olga
- Zaoui Philippe
- Zeig Steven
- Zeng Longyi
- Zhang Hao
- Zhang Yanlin
- Zhang Ying
- Zhao Zhiquan
- Zhdanova Elena
- Zheng Hongguang
- Zhong Ling
- Zhong Liyong
- Zhu Dalong
- Zhukova Larisa
- Zilahi Zsolt
- Zsom Marianna
- Zukermann Robert
- Zykova Tatyana
- Publication venue
- 'S. Karger AG'
- Publication date
- 01/01/2019
- Field of study
Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials.
Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure.
Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen.
Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049
Facile preparation and processing of aqueous dispersions of tris (8-hydroxyquinoline) aluminium (III) photoluminescent nanoparticles
- Publication venue
- Publication date
- 01/01/2009
- Field of study
Artificial Cytoskeletal Structures within Enzymatically Active Bio-inorganic Protocells
- Publication venue
- Publication date
- 01/01/2013
- Field of study
Cell paintballing using optically targeted coacervate microdroplets
- Author
- Publication venue
- 'Royal Society of Chemistry (RSC)'
- Publication date
- 01/01/2015
- Field of study
A dynamic holographic assembler was used to “paintball” stem cells with coacervate microdroplets loaded with protein, oligonucleotide or molecular dye.</p
Automation and Experience of Controlled Crystal Dehydration: Results from the European Synchrotron HC1 Collaboration
- Author
- Abergel C.
- Adachi H.
- Alexandre Gobbo
- Awad W.
- Berger M. A.
- Berman H. M.
- Bourenkov G. P.
- Bowler M. G.
- Bowler M. W.
- Brejc K.
- Brockhauser S.
- Brockhauser S.
- Chruszcz M.
- Cipriani F.
- Cramer P.
- de Sanctis D.
- Delagenière S.
- Dobbek H.
- Dobrianov I.
- Eikenberry E. F.
- Einstein J. R.
- Engel M.
- Esnouf R. M.
- Florent Cipriani
- Flory P. J.
- Flory P. J.
- Flot D.
- Fratini A. V.
- Gabadinho J.
- Gati C.
- Gupta V.
- Hall J. P.
- Hall J. P.
- Hellmich J.
- Henrich S.
- Heras B.
- Heras B.
- Hu N. J.
- Huggins M. L.
- Huxley H. E.
- Incardona M. F.
- Juan Sanchez-Weatherby
- Kadlec J.
- Kiefersauer R.
- Kiefersauer R.
- Koch M.
- Kuo A.
- Kyrieleis O. J. P.
- Larabi A.
- Leal R. M. F.
- Li J.
- Lomakin I. B.
- Longenecker K. L.
- Makde R. D.
- Malinauskaite L.
- Manfred S. Weiss
- Marjolein M. G. M. Thunnissen
- Matthew W. Bowler
- Michael G. Bowler
- Mueller U.
- Nakamura A.
- Newman J.
- Nurizzo D.
- Oliete R.
- Olof Svensson
- Owen R. L.
- Owen R. L.
- Pellegrini E.
- Perutz M. F.
- Pickford M. G.
- Powell H. R.
- Rajendran C.
- Raoult F.-M.
- Royant A.
- Russi S.
- Sadeghi R.
- Sadeghi R.
- Sam M. D.
- Sanchez-Weatherby J.
- Sandor Brockhauser
- Sauter N. K.
- Silvia Russi
- Sjogren T.
- Strong M.
- Svensson G.
- Thomas L-M. Sorensen
- Thomas Ursby
- Ursby T.
- Uwe Mueller
- Vijayalakshmi L.
- Viola R.
- Wakatsuki S.
- Warkentin M.
- Wheeler M. J.
- Yap T. L.
- Zerrad L.
- Zhang Z.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesuyi Abidemi
- Adeyeye Ademola
- Adham Walid
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adnan Ahmad Bin
- Adu-Aryee Niiarmah
- Afana Samah
- Afandy Ahmed
- Afifi Ahmed Mohamed
- Africa South
- Agalianos Christos
- Agarwal Arnav
- Agbedinu Kwabena
- Agius Marija
- Aglan Amro
- Aguilar Wendy Leslie Messa
- Aguilar-Jimenez Jose
- Aguilera Maria Lorena
- Aguilera Omar
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahmed Ahmed
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Emad Ali
- Ahmed Hala
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahmed Soliman Magdy
- Ahounou Ernest Yemalin Stephane
- Aigrain Yves
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi E
- Ajiboye Anthony
- Akatibo Emmanuel
- Akeel Nouf
- Akoto Elliot
- Al-Aarag Asmaa Abdel-Rahman
- Al-Azraqi Israa Abdullah Aziz
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-Faifi Jubran J
- Al-faqawi Maha
- Al-farram Hadeel
- Al-Hameedi Hasan Ismael Ibraheem
- Al-Hasani Ruqaya Kadhim Mohammed Jawad
- Al-khatib Ahmed
- Al-Mallah Abdullah
- Al-Marakby Dina
- Al-Mousa Mashael
- Al-Nahrawi Safwat
- Al-Obaedi Ossama
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-shammari Abeer
- Al-Slaibi Ibrahim
- Al-taher Taher
- Alada Muslimat
- Alahmady Omar
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Alamoudi Uthman
- Albeladi Bandar
- Albiety Adel
- Aldalaq Ahmad
- Aldhafeeri Salman
- Aledrisy Mohannad
- Alexander Philip
- Alexandre Challine
- Alfarsi Muayad Ahmed
- Alghamdi Ahmed
- Alghamdi Basim
- Alghamdi Masood
- Alghamdi Mohammed Saleh A.
- Algohary Osama
- Alhabli Ibrahim
- Alhady Khaled
- Alhassan Basmah
- Alhazmi Wedyan
- Alhendy Mohammed
- Alherz Mohammad
- Ali Ahmad
- Ali Ahmed
- Ali Ased
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Farah Mahmoud
- Ali Hussein
- Ali Safia
- Ali Samuel Sani
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Alihonou Thierry
- Alimi Quentin
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Aljohani Emad
- Aljohani Saud
- Alkaaki Aroub
- Alkammash Abdelrahman
- Alkelani Muhammad
- Alkhabbaz Dalia
- Allam Meran
- Allam Mostafa
- Allam Yomna
- Allegri Andrea
- Allen John Lee Y
- Almallah Ahmad
- Almanon Christel Leanne
- Almoflihi Abdullah
- Almuallem Sultan
- Almy Jack
- Alnaby Mohamed Hassab
- Alnawam Ehab
- Alnuqaydan Saleh A.
- Alnusairat Aseel
- Alomar Ibrahim N.
- Alqahtani Enas
- Alqahtani Saleh
- Alrahawy Mahmoud
- Alrajraji Mawaddah
- Alrifaie Ahmad
- AlRowais Mohammed
- Alsaggaf Mohammed
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Althwainy Amani
- Altibi Ahmed
- Altinel Yuksel
- Altoe Fernanda
- Altwigry Abdulrahman M.
- Altwijri Abdulaziz
- Alvarez Ismael Isaac Zelada
- Alvi Abdul Rehman
- Alwafai Mohammad Ghassan
- Aly Abouelatta Khairy
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alyami Rifan
- AlYoussef Ibrahim
- Alzahrani Ahmed
- Alzahrani Mohammed
- Alzayat Thuraya
- Aman Nowrin F.
- Amandito Radhian
- Ambrozeviciute Viktorija
- Ameen Mohamed
- Amer Mohamed A
- Amin Hager Abdul Aziz
- Amin Jasim
- Amin Shadid Al
- Amjad Mohammadasim
- Ammar Mohamed
- Ammar Mohamed Sabry
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson-Knight Hannah
- Andersson Linda
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Antar Sarah
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Abdul Wahid
- Anwar Nourhan
- Anwer Wahid
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aql Shaimaa
- Aquilino Fabrizio
- Arachchi Prasad Pitigala
- Arachchige Lalith Asanka Jayasooriya Jayasooriya
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Araujo Rafael
- Arcudi Claudio
- Ardley Rohan
- Arenas Andy
- Aristizã¡bal Fred Alexander Naranjo
- Arman Sam
- Armellini Andrea
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arsyad Hasbi Maulana
- Arthur Tom
- Arulampalam Tan
- Aruldas Neerav
- Asal Mohamed
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Asele Frehun Ayele
- Ashal Gehad El
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Ashton Annelisse
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Assouto Pamphile A
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Ali Amin Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Atkinson Kieran
- Atobatele Kazeem
- Attallah Noura A.
- Attar Samaa Mahmoud Al
- Attard Myranda
- Attia Attia
- Attia Attia Mohamed
- Augestad Knut Magne
- Aung Kyaw Phyo
- Austraite Aiste
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awuku-Asabre Joseph
- Awwad Saad Al
- Ayad Sara
- Ayandipo Omobolaji O
- Ayyar Shruti
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azmitia José René Arévalo
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badr Ahmed
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin M
- Badwi Nermin Mohamed
- Badwy Assmaa
- Bahar Suraya
- Baheeg Mohamad
- Bailey Karen
- Baird Alan
- Bakhaidar Mohamad
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Baldacchino Matthew
- Balducci Genoveffa
- Balila Reem Mohammed Hassan
- Balkan Ali Zeynel Abidin
- Ball Alasdair
- Ballouhey Quentin
- Balmaceda Rubén
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamicha Anastasia
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baraka Heba
- Barakat Sara Abd Elmageed
- Barendegere Venerand
- Barkolias Christos
- Barnabas Gandau Naa
- Barneo Luis
- Barrantes Ana Maria Sandoval
- Barrawi Fayez Elian Al
- Barreda Luis Miguel Alvarez
- Barrientos Linda Alvi Madrid
- Barrios Emanuel
- Barrios Emmanuel
- Basilicò Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Celeste Del
- Basso Stefano M. M
- Bastawis Fatema Al
- Basto Carlos Alejandro Arroyo
- Bautista Ana Cecilia Manchego
- Beasley William
- Bedada Alemayehu Ginbo
- Bediako-Bowan Antoinette
- Behar Nebil
- Beisa Virgilijus
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleño Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Bermúdez Ysabel Esthefany Alejos
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bezzina Maureen
- Bhangu Aneel
- Bhat Sriram
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Birindelli Arianna
- Birring Amerdip
- Björklund Ida
- Blanco Ruth
- Blencowe Natalie
- Bliksøen Marte
- Blower Emma
- Boakye-Yiadom Kwaku
- Bocchetti Tommaso
- Bode Chris
- Bode Christopher
- Boijsen Magnus
- Bonavia Karl
- Bonavina Luigi
- Bondin John
- Bondurri Andrea
- Boni Davide De
- Boni Silvia
- Bonnard Arnaud
- Bonney William
- Bono Phoebe De
- Borda-Luque Giuliano
- Borg Elaine
- Borin Eva
- Bortolasi Luca
- Botero Jaime Andres Montoya
- Botes Stefan
- Bottini Corrado
- Botto Nathalie
- Bouali Ourdia
- Bougard Heather
- Boukhal Khaoula
- Bowabsak Alaa
- Bowe Ross
- Bowley Doug
- Bradulskis Saulius
- Bratu Matei
- Bratu Matei Razvan
- Bratu Razvan-Matei
- Braungart Sarah
- Bravo Jorge Armando Chungui
- Bray Lemuel Davies
- Breitenstein Stefan
- Bréaud Jean
- Brincat Svetlana Doris
- Brocca Antonella La
- Broch Aline
- Brown Damien
- Brown James
- Brown Jason
- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Bugeja Roberta
- Buisson Philippe
- Bukari Mohammed
- Burger Sule
- Burmistrovas Andrius
- Burns Hannah
- Bustangi Nasir
- Butt Muhammad Talha
- Cabrera Carla Cecilia Ramãrez
- Cacurri Alban
- Cadogan Diana Duarte
- Cahill Ronan
- Callan Rory
- Calua Alexander Canta
- Camacho Rony
- Cameron Brian
- Camilleri Georgette Marie
- Camilleri-Brennan John F.
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canto Massimiliano Dal
- Capito Carmen
- Carabott Kurt
- Cardozo Jorge Torres
- Cardozo Ramón Augusto Melo
- Careta Maíra Cassa
- Carlucci Michele
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Carreira Jo-Anne
- Cassar Kristina
- Castillo Vanessa Dina Palomino
- Castro Manuel Rodriguez
- Catani Marco
- Cautiero Roberto
- Cecilia Tolg
- Celis Jose María Vergara
- Cengiz Yücel
- Ceriani Chiara
- Chachulski Witold
- Chai Chu-Ann
- Chai Feng Yih
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Chang Kate Yu-Ching
- Chapman Stephen J
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Tzu-Ling
- Chenn Roxanne
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chew Luen Shaun
- Chibuye Chali
- Chiesa Deborah
- Chin Pui Xin
- Chiong Jose Antonio Cabala
- Chiu Selina
- Chiu Selina Man Yeng
- Choi Philip
- Chong Bryon Frankie Hon Khi
- Chong Chean Leung
- Chong Choon Seng
- Chong Hoong-Yin
- Chow Crystal Yern Nee
- Chu Kathryn
- Chung Kuet Jun
- Chung Siyi
- Ciccioli Eleonora
- Cirocchi Roberto
- Ciubotaru Cezar
- Claire Raquillet
- Clarissa Audrey
- Clegg-Lamptey Joe-Nat
- Clement Keiran David
- Clements Joshua Michael
- Clerico Giuseppe
- Clifford Caroline
- Cloro Luigi Maria
- Coccolini Federico
- Cocker DM
- Cocorullo Gianfranco
- Cohen David Monterroso
- Coletta Diego
- Coletti Massimo
- Colombani Jean-Francois
- Cona Camilla
- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C.
- Connor Katie
- Conte Annalisa lo
- Contreras-Vergara Ana Lucia
- Coomber Ross
- Coompson Christian Lari
- Corbellini Carlo
- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Correa Juan Camilo
- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Cross Kate
- Cruz Danilo Herrera
- Cruz Herman
- Cucumazzo Stefano
- Curletti Gianluca
- Currow Chelise
- Cury Alyne Daltri Lazzarini
- D'aguzan Nicole
- D'amours Scott K
- D'cruz Reuban
- Dabboor Majd
- Dabbour Kareem
- Dabessa Daniel
- Dablouk Mohamed
- Dablouk Mohammed Osman
- Dagoe Enoch
- Dahab Ali Abo El
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
- Dambrauskas Zilvinas
- Dan Ionasc
- Danelli Piergiorgio
- Daniyan Muhammad
- Danys Donatas
- Dao Weihei
- Daqeeq Abdullah
- Dar Manzoor
- Dar Wasim
- Dardenne Sabrina
- Darweesh Mariam
- Darwish Abdelrhman KZ
- Das Andre
- Das Kaustuv
- Das Suparna
- Dassah Victor
- Davies James
- Davies Justine
- Davor Anthony
- Dawnay Giles
- Dawood Khaled
- Dawoud Hossam
- Dayie Makafui
- Deane Chelsea
- Debrah Sam
- Deckelbaum Dan L
- Decoud Horacio Paredes
- Dedekind Britta
- Dedey Florence
- Deen Khaled Naser El
- Deichsel Fabian
- Delforge Xavier
- Delgado Juan Marcelo
- Delgado Mitchelle Solange De Fã Tima Linares
- Dell Angela
- Denewar Adel
- Depalma Norma
- Deputy Mohammed
- Der Yishan
- Dervenis Christos
- Despotidis Vasileios
- Desta Semay
- Deutschmann Peter
- Devadasar Giridhar H
- Dénakpo Max
- Dharamshi Hasnain Abbas
- Diab Ahmed
- Diaconescu Bogdan
- Diaconescu Ionut-Bogdan
- Dias Stephen
- Diaz-Zorrilla Carmina
- Dickfos Marilla
- Dijan Emilio
- Dimech Thea
- Dindyal Shiva
- Djivoh Fernande
- Domini Edgar
- Dorani Radin Mohd Nurrahman Radin
- Dossou Francis
- Dousset Bertrand
- Dragatas Deividas
- Drake Thomas M
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- Elgendy Fatimah I
- Elgheriany Mohammed
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- Elnajjar Mahmoud A.
- Elnemr Abdelrhman Essam
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- Elsawy Amira
- Elsayed Makki
- Elsayed Mohammed
- Elsayed Nada Ahmed Reda
- Elsayed Nadin
- Elsayed Zaynab M
- Elsebaaye Abdelrhman Osama
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- Har Prisca A. L.
- Haraux Elodie
- Haroun Abdelrahman
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- Kandil Ahmedali M
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- Kirby Andrew
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- Kiudelis Mindaugas
- Kjellin Ann
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- Knight Stephen R
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- Morsi Ashraf
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- Morton Dion
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- Morton Robert
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- Mostafa Hassan Ali
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- Muralha Nuno
- Musa Ahmed Elgaili Khalid
- Musleh Aseel
- Mustafa Mennat-Allah
- Mustafa Mohamed
- Mustafa Mousa
- Musyoka Caroluce K
- Mutabazi Alphonse Zeta
- Muzio Elena
- Nabawi Ayman
- Nada Fathee
- Nadeem Najwa
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- Nashat Mohamed
- Nashidengo Puyearashid
- Nasir Abdulrasheed A
- Nasir Wan Nurul ‘Ain Wan Mohd
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- Natalie Hani
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- null null
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- Rudzenskaite Anele
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- Saad Mahmoud M.
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- Sabe Ahmad
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- Sabeeh Lubna
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- Saidbadr Ahmed
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- Sakr Rokia
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- Salah Osama Mohamed
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- Sam Zi Hao
- Samalavicius Narimantas E.
- Samaniego Camila Sanchez
- Samaraweera Dulan Irusha
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- Saravia Fridiz
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- Selvaggi Francesco
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- Servin Gustavo Rodolfo Pertersen
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- Seyoum Nebyou
- Sfougaris Dimitrios
- Sgroi Giovanni
- Shaalan Mohamed
- Shabkah Alaa
- Shachykava Tatsiana
- Shah Apar
- Shah Jamie
- Shah Rohi
- Shaharuddin Shahadatul
- Shaheen Alaa
- Shahine Ahmed
- Shahzad Noman
- Shaikh Nihaal
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- Shalabi Ahmad
- Shalaby Mahmoud
- Shalaby Mostafa
- Shamasneh Ala
- Shamsedine Ahmed W.
- Shamsi Ghina Shamim
- Sharpin Claire
- Shatkar Veereanna
- Shaw Catherine A
- Shawki Marwan
- Shawky Martina Yusuf
- Shawqi Muhammad
- Sheehan Jacqueline
- Shehata Sherif
- Sherman Thomas
- Sheshe Abdulrahman
- Sheshe Abdurrahaman
- Sheta Ahmed
- Shimy Gamal
- Shiwani Haaris A.
- Shiwani Hunain
- Sholadoye Tunde
- Shoura Yousra El
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- Shu Sebestian
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- Siguantay Miguel
- Sii Samuel S. Y.
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- Sleem Mohamed
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- Song Jiheon
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- Staerkle Ralph F
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- Tale Luis
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- Tawfik Badreldin Adel
- Tawfik Gehad
- Teasdale Ella
- Tedeschi Umberto
- Tedjaatmadja Chintya
- Telfah Muwaffaq Mezeil
- Tembo Thelma
- Temoche Edilberto
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- Teufelberger Gerfried
- Tew Yong Yong
- Tewari Shirish
- Thabet Waleed
- Thanusan Vimalakanthan
- Tharmalingam Shivanee
- Theodosopoulos Theodosios
- Thollot Aurore
- Thomas Efeson
- Thomas Hannah S
- Thompson Ben
- Thorarinsdottir Hildur
- Thorell Anders
- Thorsen Kenneth
- Ticona Willy Alcca
- Timothy Oyediran Kehinde
- Ting Jesse Ron Swire
- Toeema Aliaa Gamal
- Toit Frederick Du
- Tolba Hager
- Tolg Cecilia
- Tolonen Matti
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- Torres Shalon Guevara
- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Aung Kyaw
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turner Megan
- Tutino Roberta
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- Tyler Robert
- Tze R. Goh Ern
- Tze Reuben Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ugalde Paul
- Ukwenya Yahaya
- Uluşahin Mehmet
- Upadhyaya Vijaid
- Upchurch Emma
- Urbanavicius Linas
- Urniežius Zigmantas
- Urquizu Mario Contreras
- Usaityte Ausrine
- Uščinas Laimonas
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- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldaña María
- Valioulis Ioannis
- Vargas Marvin
- Varkalys Karolis
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Vega Gustavo Miguel Machain
- Velasquez Ricardo
- Velásquez Armando José Román
- Velásquez Carlos Iván Pérez
- Vella-Baldacchino Martinique
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venugopal Caranj
- Verjee Azmina
- Vermaas Maarten
- Veronese Ezio
- Vianna Julia Guasti Pinto
- Vicario Erika
- Vida Lucian Corneliu
- Vilčinskas Mantas
- Villa Roberta
- Villalobos Santiago
- Vimalachandran Dale
- Vincent Joe
- Violi Paola
- Višinskas Petras
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- Vlachogiorgos Apostolos
- Vollmer Sebastian
- Voulgaris Evangelos
- Wael Noha
- Wagener Mark
- Waleed Hamza
- Walędziak Maciej
- Walsh Michael
- Waqar Muhammad
- Warda Mahmoud
- Warren Oliver
- Waterman Ade
- Watts Anna
- Weber Beatrix
- Weber Per
- Weiser Thomas G
- Wheeler James
- Whitaker John
- White Timothy
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Wild Jonathan R L
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Witherspoon Paul
- Wogensen Fredrik
- Woin Evelina
- Wold Trude Beate
- Wolf Bernhard
- Wondimu Sahlu
- Wondoh Paul
- Wong Chee Siong
- Wong Chui Yee
- Wong Hong Yee
- Wood Greta
- Woodward Helen
- Worku Mengistu
- Worku Tewodros
- Wredberg Cecilia
- Wright Naomi J
- Xerri Thelma
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yaseen Tahir
- Yaseen Tahir Muhammad
- Yavuz Mehmet Ali
- Ye Joselyn
- Yeang Li Jing
- Yeo Lee Shi
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yip Chingwan
- Yip Sebastian Bernardo Shu
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yong Cheryl Ou
- Yong Guo Liang
- Youssef Daniel
- Youssef Haney
- Youssef Mohamed
- Youssif Jehad Hassan
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zachariades Dimitris-Christos
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zalabia Mohamed F
- Zamarin Kresimir
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zardab Ali
- Zegarra Sergio
- Zerihun Abebe Bekele
- Zhang Zhongtao
- Zheng Fei
- Zidan Hagar
- Zidan Mohamed
- Ziff Oliver
- Zil-E-Ali Ahsan
- Zohair Ahmed
- Zuber Markus
- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesuyi Abidemi
- Adeyeye Ademola
- Adham Walid
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adnan Ahmad Bin
- Adu-Aryee Niiarmah
- Afana Samah
- Afandy Ahmed
- Afifi Ahmed Mohamed
- Africa South
- Agalianos Christos
- Agarwal Arnav
- Agbedinu Kwabena
- Agius Marija
- Aglan Amro
- Aguilar Wendy Leslie Messa
- Aguilar-Jimenez Jose
- Aguilera Maria Lorena
- Aguilera Omar
- Aguilera-Arevalo Maria-Lorena
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- Akeel Nouf
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- Al-Aarag Asmaa Abdel-Rahman
- Al-Azraqi Israa Abdullah Aziz
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- Al-Faifi Jubran J
- Al-faqawi Maha
- Al-farram Hadeel
- Al-Hameedi Hasan Ismael Ibraheem
- Al-Hasani Ruqaya Kadhim Mohammed Jawad
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- Azizeldine Mohammed G.
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- D'amours Scott K
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- Dablouk Mohamed
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- Deckelbaum Dan L
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- Dossou Francis
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- Dragatas Deividas
- Drake Thomas M
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- El-Kashef Hussein
- El-Latif Nadia Khalid Abd
- El-Ma'doul Angham Solaiman
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- El-Sehily Ahmed
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- El-Sheemy Hatem
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- Elabdin Hagir Zain
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- Elazayem Ahmed Abo
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- Elbisomy Khaled Hesham
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- Elfarargy Arwa
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- Elgendy Fatimah I
- Elgheriany Mohammed
- Elhadad Alaa
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- Elhendawy Abdelaziz Osman Abdelaziz
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- Elhusseiny Ahmed Abd Elmoen
- Elkadsh Iman
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- Elkelany Ahmed
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- Elkholy Ahmed
- Elkholy Shimaa Said
- Elkolaly Salma Said
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- Elmashala Amjad
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- Elnagar Ahmedglal
- Elnajjar Mahmoud A.
- Elnemr Abdelrhman Essam
- Elrazek Aly Abd
- Elsabbagh Nourhan
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- Elsawy Amira
- Elsayed Makki
- Elsayed Mohammed
- Elsayed Nada Ahmed Reda
- Elsayed Nadin
- Elsayed Zaynab M
- Elsebaaye Abdelrhman Osama
- Elsehimy Mohamed
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Kareem
- Elshafay Abd Elrahman
- Elshami Mohamedraed
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- Elsheikh Shereen
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- Elsherbiny Abdallah Salah
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- Elsobky Soaad
- Elsorogy Diaa Eldin Abdelazeem Amin
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- Elzahed Nada
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- Farag Ahmed
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- Farfan Erick Samuel Florez
- Farhad Mustafa
- Farhan-Alanie Muhamed M H
- Farinella Eriberto
- Farmakis Konstantinos
- Farouk Sara Amr Mohamed
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- Fattah Ahmad Abdel
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- Fergany Alaa
- Fergusson Stuart J
- Fermani Claudio
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- Foco Maurizio
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- Fowler Alexander J
- Fozard Thomas
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- Furqan Muhammad Mohsin
- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
- Gad Mariam O.
- Gadelkarim Mohamed
- Gadhvi Vijay
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- Gheith Ahmed
- Ghetia Millika
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- Ghoneem Mohamed
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- Giardino Francesco Ruben
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- Gilbert Richard
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- Giles James
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- Gohar Muhammad El-Saied Ahmad Muhammad
- Gokani Shyam
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- Gosling Simon
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- Hajeh Haidar
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- Halawany Mohamed El
- Halhouli Oday
- Hall Nigel J
- Hall Tom Falconer
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- Hamad Maha Gamal Mohamad
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- Hanoun Sakhaa
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- Hantour Usama
- Hany Ethar
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- Sanchez Belen
- Sanchez Diana
- Sander Anthony
- Sandler Simone
- Santos Diogo Vinicius dos
- Saqlain Muhammad
- SAR Hong Kong
- Saravia Fridiz
- Sarmah Panchali
- Sarsik Sameh
- Sarwary Sayed
- Sasia Diego
- Satoskar Rajeev
- Satoskar Savni
- Sauvat Frederique
- Saverio Salomone Di
- Saw Jian Er
- Sayed Abdelrahman
- Sayed Farrag
- Sayed Gehad Samir El
- Sayed Islam Magdy El
- Sayed Marwa
- Sayma Eman Adel
- Scalabre Aurelien
- Schadde Erik
- Schiavone Roberto
- Schivo Debora
- Schmid Roger
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- Schoewe Christin
- Schuetz Tobias
- Schultz Johannes Kurt
- Scicluna Ruth
- Segundo Luiz Carlos Barros De Castro
- Seif Mostafa
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- Seisa Mohamed
- Seisay Sam
- Selvaggi Francesco
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- Semeda Nourhan
- Senanayake Wanigasekara Senanayake Mudiyanselage Kithsiri Janakantha
- Servin Gustavo Rodolfo Pertersen
- Setiawan Jonny
- Seto Djifid Morel
- Seyoum Nebyou
- Sfougaris Dimitrios
- Sgroi Giovanni
- Shaalan Mohamed
- Shabkah Alaa
- Shachykava Tatsiana
- Shah Apar
- Shah Jamie
- Shah Rohi
- Shaharuddin Shahadatul
- Shaheen Alaa
- Shahine Ahmed
- Shahzad Noman
- Shaikh Nihaal
- Shaker Heba
- Shaker Ramadan
- Shaker Ramdan
- Shakshouk Hend Adel Gawad
- Shalabi Ahmad
- Shalaby Mahmoud
- Shalaby Mostafa
- Shamasneh Ala
- Shamsedine Ahmed W.
- Shamsi Ghina Shamim
- Sharpin Claire
- Shatkar Veereanna
- Shaw Catherine A
- Shawki Marwan
- Shawky Martina Yusuf
- Shawqi Muhammad
- Sheehan Jacqueline
- Shehata Sherif
- Sherman Thomas
- Sheshe Abdulrahman
- Sheshe Abdurrahaman
- Sheta Ahmed
- Shimy Gamal
- Shiwani Haaris A.
- Shiwani Hunain
- Sholadoye Tunde
- Shoura Yousra El
- Shu Sebastian
- Shu Sebestian
- Shubianok Maryna
- Shwky Ayman
- Siaw Jia Yng
- Sieda Basem
- Sierra Sebastian
- Siguantay Miguel
- Sii Samuel S. Y.
- Sila George Christian Manrique
- Sila George Manrique
- Sileri Pierpaolo
- Silva Luana Ayres Da
- Silvani Paolo
- Silvestre Barbara Pereira
- Silvestri Vania
- Simioni Andrea
- Simoes Romeo Lages
- Simutis Gintaras
- Sishuba Nosisa
- Sivaganesh Sivasuriya
- Skardžiukaitė Austė
- Skehan Jennifer
- Skelly Brendan
- Slam Mohamed Abd El
- Slapelyte Evelina
- Sleem Ahmad Saber
- Sleem Mohamed
- Smart Neil
- Snaith Ailsa Claire
- Snyder Elizabeth
- Sobnach Sanju
- Soeselo Daniel Ardian
- Solaini Leonardo
- Soley Rafael
- Soliman Abdelrahman
- Soliman Ahmed
- Soliman Ahmed Ragab
- Soliman Noha Abdullah
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- Soliman Samar
- Soliman Yasmin
- Solis Ludwing Alexander Zeta
- Sollazzo Viviana
- Song Jiheon
- Soon Wai Cheong
- Souaibou Yacoubou Imorou
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- Spence Richard
- Spina Andrew
- Sproule Lorraine
- Sreedharan Anjana
- Sroor Fathy
- Sruogiene Elena Zdanyte
- Staerkle Ralph F
- Starr Nichole
- Steccanella Francesca
- Stefanopoulos Anastasios
- Stock Simon
- Stoddart Michael
- Straten Stephanie Van
- Strazdas Andrius
- Strupas Kestutis
- Stuva Jessica Patricia Gonzales
- Styles Kristian
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- Subaie Norah Al
- Subocius Andrejus
- Suleiman Siyaka Itopa
- Sund Malin
- Sundstrom Sami Martin
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- Swann Joanna
- Syibrah Khuzaimah Zahid
- Sykes Mark
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- Szeto Kylie Joan-yi
- Søreide Jon Arne
- Søreide Kjetil
- Tabiri Stephen
- Tackie Enoch
- Taddei Antonio
- Tade Adesoji
- Taha Emad Mohamed Saeed
- Tahboub Haya
- Taher Ayman And
- Taher Mustafa Mohammed
- Taieb Chouikh
- Taiwo Agboola
- Taiwo Ogechukwu
- Talaat Muhammed
- Tale Fernando
- Tale Luis
- Talukder Shagorika
- Talving Peep
- Tammam Ahmed
- Tan Choy Ling
- Tan Jessica Juliana
- Tan Joel Kin
- Tan Keith Say Kwang
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- Tan Yi Koon
- Tanase Andrei
- Tarek Adham
- Tarek Areej
- Tarek Dina
- Targa Simone
- Tariq Sherif
- Tata Mahadevan Deva
- Tatagiba Luiza Sarmento
- Tawfik Badreldin Adel
- Tawfik Gehad
- Teasdale Ella
- Tedeschi Umberto
- Tedjaatmadja Chintya
- Telfah Muwaffaq Mezeil
- Tembo Thelma
- Temoche Edilberto
- Teo Shuang Yi
- Tessera Gaetano
- Teufelberger Gerfried
- Tew Yong Yong
- Tewari Shirish
- Thabet Waleed
- Thanusan Vimalakanthan
- Tharmalingam Shivanee
- Theodosopoulos Theodosios
- Thollot Aurore
- Thomas Efeson
- Thomas Hannah S
- Thompson Ben
- Thorarinsdottir Hildur
- Thorell Anders
- Thorsen Kenneth
- Ticona Willy Alcca
- Timothy Oyediran Kehinde
- Ting Jesse Ron Swire
- Toeema Aliaa Gamal
- Toit Frederick Du
- Tolba Hager
- Tolg Cecilia
- Tolonen Matti
- Tolotra Todisoa Emmanuella Christina
- Tori Sayeeda Aktar
- Torres Carla Pierina García
- Torres Shalon Guevara
- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Aung Kyaw
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turner Megan
- Tutino Roberta
- Tverskis Zygimantas
- Tyler Robert
- Tze R. Goh Ern
- Tze Reuben Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ugalde Paul
- Ukwenya Yahaya
- Uluşahin Mehmet
- Upadhyaya Vijaid
- Upchurch Emma
- Urbanavicius Linas
- Urniežius Zigmantas
- Urquizu Mario Contreras
- Usaityte Ausrine
- Uščinas Laimonas
- Utter Maria
- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldaña María
- Valioulis Ioannis
- Vargas Marvin
- Varkalys Karolis
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Vega Gustavo Miguel Machain
- Velasquez Ricardo
- Velásquez Armando José Román
- Velásquez Carlos Iván Pérez
- Vella-Baldacchino Martinique
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venugopal Caranj
- Verjee Azmina
- Vermaas Maarten
- Veronese Ezio
- Vianna Julia Guasti Pinto
- Vicario Erika
- Vida Lucian Corneliu
- Vilčinskas Mantas
- Villa Roberta
- Villalobos Santiago
- Vimalachandran Dale
- Vincent Joe
- Violi Paola
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- Vlachogiorgos Apostolos
- Vollmer Sebastian
- Voulgaris Evangelos
- Wael Noha
- Wagener Mark
- Waleed Hamza
- Walędziak Maciej
- Walsh Michael
- Waqar Muhammad
- Warda Mahmoud
- Warren Oliver
- Waterman Ade
- Watts Anna
- Weber Beatrix
- Weber Per
- Weiser Thomas G
- Wheeler James
- Whitaker John
- White Timothy
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Wild Jonathan R L
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Witherspoon Paul
- Wogensen Fredrik
- Woin Evelina
- Wold Trude Beate
- Wolf Bernhard
- Wondimu Sahlu
- Wondoh Paul
- Wong Chee Siong
- Wong Chui Yee
- Wong Hong Yee
- Wood Greta
- Woodward Helen
- Worku Mengistu
- Worku Tewodros
- Wredberg Cecilia
- Wright Naomi J
- Xerri Thelma
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yaseen Tahir
- Yaseen Tahir Muhammad
- Yavuz Mehmet Ali
- Ye Joselyn
- Yeang Li Jing
- Yeo Lee Shi
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yip Chingwan
- Yip Sebastian Bernardo Shu
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yong Cheryl Ou
- Yong Guo Liang
- Youssef Daniel
- Youssef Haney
- Youssef Mohamed
- Youssif Jehad Hassan
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zachariades Dimitris-Christos
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zalabia Mohamed F
- Zamarin Kresimir
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zardab Ali
- Zegarra Sergio
- Zerihun Abebe Bekele
- Zhang Zhongtao
- Zheng Fei
- Zidan Hagar
- Zidan Mohamed
- Ziff Oliver
- Zil-E-Ali Ahsan
- Zohair Ahmed
- Zuber Markus
- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially