Schwannoma celular retroperitoneal

We present the case of a female patient, 35 years old, who had a complaint of sporadic left flank pain for 5 years. She said she had no comorbidities. The results of the laboratory tests did not show abnormalities. Previous ultrasonography of the urinary tract (without the use of color Doppler) described a possible single cyst postero-inferiorly to the left renal pelvis. In recent ultrasound we observed that topography massive oval formation markedly hypoechoic with discrete intermingled flow. Subsequent abdominal computed tomography and magnetic resonance imaging characterized retroperitoneal mass along the hilum of the left kidney, associated with renal dimensional reduction and ipsilateral hydronephrosis. Histological diagnosis after tumor excision: cell schwannoma (Antoni A histological standard only).Apresentamos o caso de paciente do gênero feminino, 35 anos, atendida com queixa de dores esporá- dicas no flanco esquerdo por 5 anos. Negou comorbidades. Exames laboratoriais sem anormalidades. Ultrassonografias prévias do aparelho urinário (sem o uso de Doppler colorido) descreveram possível cisto simples póstero-inferiormente a pelve renal esquerda. Em ultrassonografia recente observou-se, nessa topografia, volumosa formação ovalada, acentuadamente hipoecóica, com discreto fluxo de permeio. Tomografia computadorizada e ressonância magnética abdominais subsequentes caracterizaram massa retroperitoneal junto ao hilo do rim esquerdo, associada à redução dimensional renal e hidronefrose ipsilaterais. Diagnóstico histológico pós-exérese tumoral: schwannoma celular (somente padrão histológico Antoni A)

O império dos mil anos e a arte do "tempo barroco": a águia bicéfala como emblema da Cristandade

The article reveals that between the mid-17th century and the mid-18th century, in the ecclesiastical world of the religious orders (Jesuits, franciscans, Carmelites, Cistercians, Augustinian, etc.) and the episcopate, there was the progressive adoption of the imperial symbol, the double-headed eagle, attribute of the Christian Empire, the germanic Holy Roman Empire emblem. However, in the religious field, this imperial eagle of the baroque time appears without the political insignia (sword, scepter and the imperial orb), adorning altars, monstrances, trumphal archs, facades of temples, doors, walls, domes, pulpits, sacred washbasins, sculptures and paintings of the Virgin and Child, liturgical robes, etc.; therefore related to the cult and the dogmas of the Catholic faith - in artistic works, the association between the double eagle and the flesh-spirit or human-divine unity, axial principle of the Catholic faith, represented by Virgin-Mother and Christ, is often indicated directly. The research has located and identified numerous remnants of the double eagle emblem in religious field in Portugal and Spain and in their conquests and dominions in America, Asia and Africa, and also in Italy, and the historiography on painful birth of the modern era in the West has never realized this phenomenon. Symbolizing absolute power, universal power, these works with sacred significance, as the ecclesiastical discourse of the time, demonstrate movement occurred in religious plane. With the aim to assert not only spiritual but also temporal power of Christ and his mystical body, the Church was impelled by the idea of restoring the "Republica Christiana" or Christendon - disrupted by conflicts of power and faith - and of introducing a Universal Apostolic Monarchy extended to all mankind: the Empire of the Last Days, the Empire of Christ in the world, the fifth Empire

Reactive interstitial and reparative fibrosis as substrates for cardiac ectopic pacemakers and reentries

This book constitutes the refereed proceedings of the 4th International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2016, held in Granada, Spain, in April 2016. The 69 papers presented were carefully reviewed and selected from 286 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; biomedical image analysis; biomedical signal analysis; computational systems for modeling biological processes; eHealth; tools for next generation sequencing data analysis; assistive technology for people with neuromotor disorders; fundamentals of biological dynamics and maximization of the information extraction from the experiments in the biological systems; high performance computing in bioinformatics, computational biology and computational chemistry; human behavior monitoring, analysis and understanding; pattern recognition and machine learning in the -omics sciences; and resources for bioinformatics.Dangerous cardiac arrhythmias have been frequently associated with focal sources of fast pulses, i.e. ectopic pacemakers. However, there is a lack of experimental evidences that could explain how ectopic pacemakers could be formed in cardiac tissue. In recent studies, we have proposed a new theory for the genesis of ectopic pacemakers in pathological cardiac tissues: reentry inside microfbrosis, i.e., a small region where excitable myocytes and non-conductive material coexist. In this work, we continue this investigation by comparing different types of fibrosis, reparative and reactive interstitial fibrosis. We use detailed and modern models of cardiac electrophysiology that account for the micro-structure of cardiac tissue. In addition, for the solution of our models we use, for the first time, a new numerical algorithm based on the Uniformization method. Our simulation results suggest that both types of fibrosis can support reentries, and therefore can generate in-silico ectopic pacemakers. However, the probability of reentries differs quantitatively for the different types of fibrosis. In addition, the new Uniformization method yields 20-fold increase in cardiac tissue simulation speed and, therefore, was an essential technique that allowed the execution of over a thousand of simulations.Peer Reviewe