Value Relevance of GRI Economic and Ethics/Integrity Disclosure among Listed Manufacturing Firms in Nigeria: The Role of Ownership Concentration

oai:ojs2.fujafr.fudutsinma.edu.ng:article/1This study evaluates the value relevance of GRI Economic and Ethics/Integrity Disclosures among listed Manufacturing Firms in Nigeria. It also investigates the role of ownership concentration in influencing the value relevance of GRI disclosures. The study adopted the purposive sampling technique to select a sample of 43 listed Manufacturing Firms on the Nigerian Exchange Group (NGX) for the 8-year period from 2014–2021. The study used the Ohlson (1995) model to analyze the value relevance of GRI Economic and Ethics/Integrity Disclosures. The results of the study showed that GRI Economic Disclosure, Ethics/Integrity Disclosure and Ownership Concentration are value relevant in the Nigerian listed Manufacturing Firms. Further, the study found that ownership concentration has a significant moderating influence on the value relevance of GRI Economic and Ethics/Integrity Disclosures among listed Manufacturing Firms in Nigeria. The results of the study provide evidence that listed Manufacturing Firms should pay special attention to GRI Economic and Ethics/Integrity Disclosures in order to enhance firm value and investor decision-making. The study contributes to the extant literature by being the first to investigate the value relevance of GRI Economic and Ethics/Integrity Disclosures and the role of ownership concentration among listed Manufacturing Firms in Nigeria. The study recommends that listed Manufacturing Firms should respond to the GRI Economic and Ethics/Integrity Disclosure requirements in order to enhance firm value

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Background Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack number. Participants, care givers, and those assessing outcomes were masked to allocation. We originally planned to enrol 15 000 women with a composite primary endpoint of death from all-causes or hysterectomy within 42 days of giving birth. However, during the trial it became apparent that the decision to conduct a hysterectomy was often made at the same time as randomisation. Although tranexamic acid could influence the risk of death in these cases, it could not affect the risk of hysterectomy. We therefore increased the sample size from 15 000 to 20 000 women in order to estimate the effect of tranexamic acid on the risk of death from post-partum haemorrhage. All analyses were done on an intention-to-treat basis. This trial is registered with ISRCTN76912190 (Dec 8, 2008); ClinicalTrials.gov, number NCT00872469; and PACTR201007000192283. Findings Between March, 2010, and April, 2016, 20 060 women were enrolled and randomly assigned to receive tranexamic acid (n=10 051) or placebo (n=10 009), of whom 10 036 and 9985, respectively, were included in the analysis. Death due to bleeding was significantly reduced in women given tranexamic acid (155 [1·5%] of 10 036 patients vs 191 [1·9%] of 9985 in the placebo group, risk ratio [RR] 0·81, 95% CI 0·65–1·00; p=0·045), especially in women given treatment within 3 h of giving birth (89 [1·2%] in the tranexamic acid group vs 127 [1·7%] in the placebo group, RR 0·69, 95% CI 0·52–0·91; p=0·008). All other causes of death did not differ significantly by group. Hysterectomy was not reduced with tranexamic acid (358 [3·6%] patients in the tranexamic acid group vs 351 [3·5%] in the placebo group, RR 1·02, 95% CI 0·88–1·07; p=0·84). The composite primary endpoint of death from all causes or hysterectomy was not reduced with tranexamic acid (534 [5·3%] deaths or hysterectomies in the tranexamic acid group vs 546 [5·5%] in the placebo group, RR 0·97, 95% CI 0·87-1·09; p=0·65). Adverse events (including thromboembolic events) did not differ significantly in the tranexamic acid versus placebo group. Interpretation Tranexamic acid reduces death due to bleeding in women with post-partum haemorrhage with no adverse effects. When used as a treatment for postpartum haemorrhage, tranexamic acid should be given as soon as possible after bleeding onset. Funding London School of Hygiene & Tropical Medicine, Pfizer, UK Department of Health, Wellcome Trust, and Bill & Melinda Gates Foundation

Bilaterally symmetrical foramina on the parietal bone of the bovine skull: a case report

Different bovine skull developmental defects have been reported with variable frequency of occurrence. We hereby report a bilaterally symmetrical parietal foramina in a processed skull meant for osteological practical at the Department of Veterinary Anatomy, University of Jos, Nigeria. The depths of each of the foramina were 4.3 cm, while the diameters were 1 cm. This appears to be the first report of such foramina in the skull of bovine in North Central Nigeria.Keywords: Bovine skull, Foramina, Parietal bone, Developmental defect

Histogenesis of the stomach of helmeted guinea fowl (Numida meleagris)

The histogenesis of the stomach (proventriculus and ventriculus) of helmeted guinea fowl (Numida meleagris) was studied using light microscopy and histochemical techniques. Fifteen (15) embryos were utilized for this study. The result showed that at 10th and 13th days of embryonic development, the primordial proventriculus and ventriculus were lined by pseudostratified columnar epithelium surrounded by mesenchyme connective tissue. At 19th day of embryonic development, the epithelium of the proventriculus and ventriculus as well as the proventricular glands was lined by simple cuboidal epithelium. Tunics; tunica muscularis and serosa were evident at this stage. At 23rd day of embryonic development, tubular glands of the ventriculus became canalized. The 27th day of embryonic develoment of the primordial proventriculus showed an organized glandular lobules, central cavity and prominent muscle layer while the ventriculus showed the presence of cuticle, simple tubular glands, loose connective tissues of the lamina propria and muscle layer. This study has shown that primordial stomach appeared to be completly differentiated to definitive stomach by the 27th day with the potential of commencing functional role.Keywords: Embryo, Proventriculus, Ventriculus, Guinea fowl, Numida meleagri

Bilaterally symmetrical foramina on the parietal bone of the bovine skull: a case report

Different bovine skull developmental defects have been reported with variable frequency of occurrence. We hereby report a bilaterally symmetrical parietal foramina in a processed skull meant for osteological practical at the Department of Veterinary Anatomy, University of Jos, Nigeria. The depths of each of the foramina were 4.3 cm, while the diameters were 1 cm. This appears to be the first report of such foramina in the skull of bovine in North Central Nigeria.Keywords: Bovine skull, Foramina, Parietal bone, Developmental defect