Incorporating an Environmental Management Plan in Water Utilities Management Systems to Reduce Water Loss; Case of Non-Revenue Water in Kisumu City, Kenya

One of the biggest issues facing water utilities is the water loss experienced during the distribution process. This study sought to examine water distribution process in Kisumu and formulate an Environmental Management Plan (EMP) to minimize water loss and mitigate their negative environmental impacts. A qualitative research approach and a case study research design were employed where 25 participants from Kisumu Water and Sanitation Company (KIWASCO) were interviewed in a Focus Group Discussion (FGD). Content analysis of the data collected indicated that water quality and quantity were greatly affected by water loss and the problems associated with them included water pollution due to introduction of contaminants when leakages or pipe bursts occur and water scarcity where the water utility was unable to make up for the amount of water lost. Water abstraction technique was also identified as a vital factor that determines how much water is lost even before it gets into the distribution system. Land/soil, socioeconomic and political environment were also some of the factors identified as they form the backbone of a functional EMP. The research concluded that as much as KIWASCO has a strategic plan to minimize these water losses, the goal entirely focuses on doing so for economic gains and not to address the associated negative environmental impacts hence the recommendation that there is need to incorporate an EMP in their management systems that will not only ensure high revenue generation but also guarantee the conservation of the said water resource to achieve environmental excellence

Annual cycle of the legume pod borer Maruca vitrata Fabricius (Lepidoptera: Crambidae) in southwestern Burkina Faso

Maruca vitrata is an economically significant insect pest of cowpea in sub-Saharan Africa. Understanding the seasonal population patterns of M. vitrata is essential for the establishment of effective pest management strategies. M. vitrata larval populations on cultivated cowpea and adult flying activities were monitored in addition to scouting for host plants and parasitoids during 2 consecutive years in 2010 and 2011 in southwestern Burkina Faso. Our data suggest that M. vitrata populations overlapped on cultivated cowpea and alternate host plants during the rainy season. During the cowpea off-season, M. vitrata maintained a permanent population on the wild host plants Mucuna poggei and Daniella oliveri. The parasitoid fauna include three species, Phanerotoma leucobasis Kri., Braunsia kriegeri End. and Bracon sp. Implications of these finding for pest management strategies are discussed

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders that often progress to chemotherapy-resistant secondary acute myeloid leukemia (sAML). We used whole-genome sequencing to perform an unbiased comprehensive screen to discover the somatic mutations in a sample from an individual with sAML and genotyped the loci containing these mutations in the matched MDS sample. Here we show that a missense mutation affecting the serine at codon 34 (Ser34) in U2AF1 was recurrently present in 13 out of 150 (8.7%) subjects with de novo MDS, and we found suggestive evidence of an increased risk of progression to sAML associated with this mutation. U2AF1 is a U2 auxiliary factor protein that recognizes the AG splice acceptor dinucleotide at the 3' end of introns, and the alterations in U2AF1 are located in highly conserved zinc fingers of this protein. Mutant U2AF1 promotes enhanced splicing and exon skipping in reporter assays in vitro. This previously unidentified, recurrent mutation in U2AF1 implicates altered pre-mRNA splicing as a potential mechanism for MDS pathogenesis

An assessment of the risk of Bt-cowpea to non-target organisms in West Africa

Cowpea (Vigna unguiculata Walp.) is the most economically important legume crop in arid regions of sub-Saharan Africa. Cowpea is grown primarily by subsistence farmers who consume the leaves, pods and grain on farm or sell grain in local markets. Processed cowpea foods such as akara (a deep-fat fried fritter) are popular in the rapidly expanding urban areas. Demand far exceeds production due, in part, to a variety of insect pests including, in particular, the lepidopteran legume pod borer (LPB) Maruca vitrata. Genetically engineered Bt-cowpea, based on cry1Ab (Event 709) and cry2Ab transgenes, is being developed for use in sub-Saharan Africa to address losses from the LBP. Before environmental release of transgenic cowpeas, the Bt Cry proteins they express need to be assessed for potential effects on non-target organisms, particularly arthropods. Presented here is an assessment of the potential effects of those Cry proteins expressed in cowpea for control of LPB. Based on the history of safe use of Bt proteins, as well as the fauna associated with cultivated and wild cowpea in sub-Saharan Africa results indicate negligible effects on non-target organisms

Rethinking women in survival entrepreneurship and wellbeing in Kenya

The interplay between entrepreneurship, regional development and culture creates different experiences for female entrepreneurs. Past research critically analyzes and acknowledges the role of entrepreneurship in enhancing gender empowerment, reduction of unemployment rates and the mitigation of extreme poverty in different societies. Furthermore, it acknowledges the existence of gender disparity, which varies across context and time. In Kenya, the entrepreneurship narrative highlights its role in unemployment reduction and income generation. Women empowerment has emerged as a major benefit of female entrepreneurship in Kenya (ADB, 2016). Historically, Kenyan women play a significant role in their households. The discourse on the gains of entrepreneurship is however silent about the implications of combining these roles on the overall well-being of female entrepreneurs. Of particular interest, is how their entrepreneurial experiences, contribute to their quality of life, overall physical, psycho-social and economic wellbeing. This chapter provides a theoretical overview of female entrepreneurship in Kenya that advocates for a focus on the physical, psychosocial and economic wellbeing of female entrepreneurs as an important aspect in assessing the overall success of entrepreneurial initiatives. This overview provides a framework that gives a matrix for contextual and holistic wellbeing of female entrepreneurs in Kenya